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Journal Articles

Regulation of Iron Homeostasis By PTG-300 Improves Disease Parameters in Mouse Models for Beta-Thalassemia and Hereditary Hemochromatosis

Roopa Taranath, PhD, Gregory Bourne, PhD, Li Zhao, MD PhD, Brian Frederick, MS, Chelsea King, BA, David Liu, PhD

Blood (2019) 134 (Supplement_1): 3540.

https://doi.org/10.1182/blood-2019-129309

Published: 2019

Journal Articles

Phase 2 Clinical Trial Results for Bitopertin, an Oral Glycine Transporter 1 Inhibitor, in Patients with Non-Transfusion Dependent Beta-Thalassemia

Ali Taher, MD PhD, Vip Viprakasit, MD DPhil, Maria Domenica Cappellini, MD, Dominik Kraus, PhD, Patrick Cech, PhD, Volz Dietmar, PhD, Erica Winter, PharmD, Norman Alan Mazer, MD PhD, Stephane Nave, MD, Juergen Dukart, PhD, Franziska Schaedeli Stark, PhD, Annette Koerner, PhD, Omar Khwaja, MD PhD, Ricardo Hermosilla, DVM, PhD

Blood (2018) 132 (Supplement 1): 3635.

https://doi.org/10.1182/blood-2018-99-114776

Published: 2018

Journal Articles

A Selective ORAL GLYT1 Inhibitor, Improves Anemia and RED CELL Survival in a MOUSE MODEL of Beta-Thalassemia

Carlo Brugnara, MD, Anja Harmeier, Lucia De Franceschi, MD, Alessandro Matte, Michael Winter, Annette Koerner, Omar Khwaja, Thomas Singer, Elisabetta Beneduce, Enrica Federti, Angela Siciliano

Blood (2016) 128 (22): 1284.

https://doi.org/10.1182/blood.V128.22.1284.1284

Published: 2016

Journal Articles

Administration of Minihepcidins to Animals Affected By β-Thalassemia Major Reduces Anemia and Splenomegaly

Roberta Chessa, PhD, Ritama Gupta, MSc, Carla Casu, PhD, Robert E Fleming, MD, Yelena Ginzburg, Brian MacDonald, MB, ChB, PhD, Stefano Rivella, PhD

Blood (2016) 128 (22): 259.

https://doi.org/10.1182/blood.V128.22.259.259

Published: 2016

Journal Articles

Combination of Tmprss6 -ASO and the Iron Chelator Deferiprone Improves Erythropoiesis and Reduces Iron Overload in a Mouse Model of Beta-Thalassemia

Carla Casu, PhD, Mariam Aghajan, PhD, Rea Oikonomidau, MD, Shuling Guo, PhD, Brett P. Monia, PhD, Stefano Rivella, PhD

Blood (2014) 124 (21): 4024.

https://doi.org/10.1182/blood.V124.21.4024.4024

Published: 2014

Journal Articles

Treatment With Minihepcidin Peptide Improves Anemia and Iron Overload In a Mouse Model Of Thalassemia Intermedia

Carla Casu, PHD, Adam Goldberg, Elizabeta Nemeth, PhD, Tomas Ganz, MD, PhD, Sara Gardenghi, PhD, Brian MacDonald, Stefano Rivella, PhD

Blood (2013) 122 (21): 431.

https://doi.org/10.1182/blood.V122.21.431.431

Published: 2013

Journal Articles

Target TMPRSS6 Using Antisense Technology for the Treatment of Hereditary Hemochromatosis and β-Thalassemia

Shuling Guo, PhD, Carla Casu, Sara Gardenghi, PhD, Sheri Booten, Andy Watt, Susan Freier, Ph.D, Stefano Rivella, PhD, Brett P. Monia, PhD

Blood (2012) 120 (21): 481.

https://doi.org/10.1182/blood.V120.21.481.481

Published: 2012

Journal Articles

Removal of Macrophages From the Erythroid Niche Impairs Stress Erythropoiesis but Improves Pathophysiology of Polycythemia Vera and Beta-Thalassemia

Pedro Ramos, PhD, Carla Casu, PhD, Sara Gardenghi, PhD, Laura Breda, Ph.D, Bart J Crielaard, PhD, Ritama Gupta, Undergraduate student, Ella Guy, Maria F Mariongiu, PhD, Ross L. Levine, Omar Abdel-Wahab, PhD, Benjamin L. Ebert, Nico van Rooijen, PhD, Saghi Ghaffari, MD, PhD, Robert W Grady, PhD, Patricia Giardina, MD, Stefano Rivella, PhD

Blood (2012) 120 (21): 81.

https://doi.org/10.1182/blood.V120.21.81.81

Published: 2012

Journal Articles

Plasma Protein Oxidation and Triglyceride Levels in Sickle Cell Anemia.

Yesim Oztas, MD, Selma Unal, MD, Nuriman Ozgunes, PhD

Blood (2009) 114 (22): 2578.

https://doi.org/10.1182/blood.V114.22.2578.2578

Published: 2009

Journal Articles

Cysteine 93 of Hemoglobin Beta Chain Is the Major Target of Oxidation During Red Blood Cell Storage.

Grady R. Blacken, PhD, Yi Wang, PhD, Jose A. Lopez, MD, Xiaoyun Fu, PhD

Blood (2009) 114 (22): 4040.

https://doi.org/10.1182/blood.V114.22.4040.4040

Published: 2009

Journal Articles

Peroxiredoxin-2 (Prx2) Membrane Displacement is A New Additional Factor to the Severity of β-Thalassemic Mouse Red Cell Membrane Damage.

Alessandro Mattè, Philip S. Low, PhD, Franco Turrini, Mariarita Bertoldi, Maria Estela Campanella, Antonella Pantaleo, Angela Siciliano, Lucia De Franceschi, MD

Blood (2009) 114 (22): 2009.

https://doi.org/10.1182/blood.V114.22.2009.2009

Published: 2009

NARROW

Regulation of Iron Homeostasis By PTG-300 Improves Disease Parameters in Mouse Models for Beta-Thalassemia and Hereditary Hemochromatosis

Phase 2 Clinical Trial Results for Bitopertin, an Oral Glycine Transporter 1 Inhibitor, in Patients with Non-Transfusion Dependent Beta-Thalassemia

A Selective ORAL GLYT1 Inhibitor, Improves Anemia and RED CELL Survival in a MOUSE MODEL of Beta-Thalassemia

Administration of Minihepcidins to Animals Affected By β-Thalassemia Major Reduces Anemia and Splenomegaly

Combination of Tmprss6 -ASO and the Iron Chelator Deferiprone Improves Erythropoiesis and Reduces Iron Overload in a Mouse Model of Beta-Thalassemia

Treatment With Minihepcidin Peptide Improves Anemia and Iron Overload In a Mouse Model Of Thalassemia Intermedia

Target TMPRSS6 Using Antisense Technology for the Treatment of Hereditary Hemochromatosis and β-Thalassemia

Removal of Macrophages From the Erythroid Niche Impairs Stress Erythropoiesis but Improves Pathophysiology of Polycythemia Vera and Beta-Thalassemia

Plasma Protein Oxidation and Triglyceride Levels in Sickle Cell Anemia.

Cysteine 93 of Hemoglobin Beta Chain Is the Major Target of Oxidation During Red Blood Cell Storage.

Peroxiredoxin-2 (Prx2) Membrane Displacement is A New Additional Factor to the Severity of β-Thalassemic Mouse Red Cell Membrane Damage.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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