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Journal Articles

Mutations and Copy Number Gains of the BCL2 Family Members Mediate Resistance to Venetoclax in Multiple Myeloma (MM) Patients

Paola Neri, MD PhD, Ranjan Maity, PhD, Jean-Baptiste Alberge, Sarthak Sinha, BSc, Justin Donovan, Madison Kong, Fajer Hasan, Arzina Jaffer, Lawrence H. Boise, PhD, Nizar Bahlis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 572.
https://doi.org/10.1182/blood-2019-127593
Published: 2019
Journal Articles

T Cell Activation By OKT3 Is a Function of the Percent Monocytes in PBMC of Healthy Donors and MDS Patients

Alison Tarke, Valentina Ferrari, BA, Hannah Fields, Luca Ferrari, Franco Ferrari, PhD, Tiffany N Tanaka, MD, Rafael Bejar, MD PhD, Antonella Vitiello, Dr. Pharm., Thomas A Lane, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4870.
https://doi.org/10.1182/blood-2019-131474
Published: 2019
Journal Articles

STAT1 Transcriptional Response Predicts Molecular Responses of PB-Derived Clonogenic Cells from MPN Patients to Interferon Alpha

Milena Kalmer, MSc, Kristina Feldberg, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, MD, Nicolas Chatain, Steffen Koschmieder
Journal: Blood
Blood (2019) 134 (Supplement_1): 1679.
https://doi.org/10.1182/blood-2019-122676
Published: 2019
Journal Articles

Up-Regulation of the mRNA Expression and Plasma Activity of PADI4in Sickle Cell Anemia during Acute Crisis

Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, MSc, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson da Silva Araujo, MD PhD, Antonio Roberto Lucena-Araújo, PhD, Pedro Vieira da Silva Neto, Adriana Malheiro, PhD, Nelson Abrahim Fraiji, MD PhD, Fernando Ferreira Costa, MD PhD, Marcos André Cavalcanti Bezerra, PhD, Magnun Nueldo Nunes Santos, MSc, PhD, Erich V De Paula, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2257.
https://doi.org/10.1182/blood-2019-125630
Published: 2019
Journal Articles

DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N 6 -Methyladenine

Xiaochang Liu, PhD, Jiuxia Pang, Christopher Seiler, Ryan Kempen, Hao Liu, Aref Al-Kali, MD, Y. Natalia Tretyakova, Mark Litzow, MD, Shujun Liu
Journal: Blood
Blood (2019) 134 (Supplement_1): 2513.
https://doi.org/10.1182/blood-2019-130490
Published: 2019
Journal Articles

PI3Kδ Inhibition Enhances Sensitivity of Primary High-Risk Childhood B-Cell Acute Lymphoblastic Leukemia Cells to Glucocorticoid Chemotherapy

Jessica A.O. Zimmerman, MD, Mimi Fang, Arunkumar Modi, MBBS, MPH, Adam Dupuy, PhD, Sarah K. Tasian, MD, Miles A. Pufall, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2572.
https://doi.org/10.1182/blood-2019-129205
Published: 2019
Journal Articles

Prothrombotic State, Platelet Activation and Netosis in Systemic Lupus Erythematosus

Elena Monzón Manzano, Ihosvany Fernandez-Bello, Raul Justo Sanz, Larissa Valor, Francisco Javier López-Longo, Angel Robles, Teresa Álvarez Roman, Miguel A Canales, MD PhD, Victor Jimenez-Yuste, Nora Butta, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1141.
https://doi.org/10.1182/blood-2019-127991
Published: 2019
Journal Articles

Characterizing the Anti-Apoptotic Dependencies of T-Cell Prolymphocytic Leukemia Identifies HDAC and JAK/STAT Pathway Inhibitors As Promising Combination Partners to Augment Bcl-2 Targeted Killing By Venetoclax

Charles Herbaux, MD MSc, Christoph Kornauth, Stéphanie Poulain, MD PhD, Olivier Tournilhac, Mary C Collins, BA, Rebecca Valentin, MD, Stephen Jun Fei Chong, PhD, Jehan Dupuis, MD, Adrien Daniel, Micha Srour, MD, Cecile Tomowiak, MD, Kamel Laribi, MD, Damien Roos-Weil, Cedric Rossi, MD PhD, Nicolas Vanlangendonck, MSc, Cecile Leyronnas, Fatiha Merabet, MD, Jean Valère Malfuson, MD, Mourad Tiab, Samuel Ng, MD PhD, Franck Morschhauser, MD, Philipp Bernhard Staber, MD PhD, Matthew S. Davids, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 807.
https://doi.org/10.1182/blood-2019-126773
Published: 2019
Journal Articles

Utilizing Multiparametric Flow Cytometry to Identify Patients with Primary Plasma Cell Leukemia at Diagnosis

Laura A Evans, Dragan Jevremovic, MD PhD, Bharat Nandakumar, Francis K. Buadi, MB, CHB, Angela Dispenzieri, MD, David Dingli, MD PhD, Martha Q. Lacy, MD, Suzanne R. Hayman, MD, Prashant Kapoor, MD, Ronald S. Go, MD, Nelson Leung, MD, Amie Fonder, PA-C, MS, Miriam A. Hobbs, APRN, CNP, DNP, Yi L. Hwa, APRN, CNP, DNP, Eli Muchtar, MD, Rahma M Warsame, MD, Taxiarchis Kourelis, MD, Stephen J Russell, MD PhD, John A. Lust, MD PhD, Yi Lin, MD PhD, Mustaqeem Siddiqui, MD, Robert A. Kyle, MD, Morie A Gertz, MD, S. Vincent Rajkumar, MD, Shaji K. Kumar, MD, Wilson I Gonsalves, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4334.
https://doi.org/10.1182/blood-2019-126777
Published: 2019
Journal Articles

Reduced Antigen Presentation May Contribute to Immunomodulatory Drug Resistance in Multiple Myeloma

David G. Coffey, MD, Ola Landgren, MD PhD, Yuexin Xu, PhD, Dickran Kazandjian, MD, Trevor J. Pugh, PhD, Sacha Gnjatic, PhD, Edus H. Warren, MD PhD, Damian J. Green, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4367.
https://doi.org/10.1182/blood-2019-126222
Published: 2019
Journal Articles

Leukemic Stem Cell Phenotype Is Associated with Mutational Profile in Acute Myeloid Leukemia

Ja Min Byun, MD, Dong-Yeop Shin, MD PhD, Youngil Koh, Sung-Soo Yoon, MD PhD, Junshik Hong, MD, Inho Kim, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3852.
https://doi.org/10.1182/blood-2019-126373
Published: 2019
Journal Articles

Molecular Mechanisms of Primary Resistance to Azacitidine in MDS/AML Patients - Data of the Hellenic MDS Study Group

Vassiliki Mpakou, PhD, Aris Spathis, PhD, Anthi Bouhla, MD, Frieda Kontsioti, PhD, Zoi Tsakiraki, MD, Sotirios Papageorgiou, MD PhD, Efthimia Mpazani, MD, Irene Glezou, MD, Konstantinos Gkodopoulos, MD, Georgia Stavroulaki, MD, Athanasios Galanopoulos, MD PhD, Argiris Symeonidis, MD PhD, Nora-Athina Viniou, MD PhD, Kalliopi Zafeiropoulou, Ioannis Kotsianidis, MD PhD, Periklis Foukas, MD PhD, Vassiliki Pappa, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5403.
https://doi.org/10.1182/blood-2019-122424
Published: 2019
Journal Articles

Expression of CD47 and Calr in Myeloproliferative Neoplasms and Myelodysplastic Syndrome: Potential New Therapeutical Targets

Kristian Boasman, BSc, MSc, Matthew J Simmonds, PhD, Ciro R Rinaldi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5031.
https://doi.org/10.1182/blood-2019-128422
Published: 2019
Journal Articles

Overexpression and Targeted Activation of the Protein Phosphatases SHP-1 Abrogates Survival Pathways in Large Granular Lymphocyte Leukemia (LGLL)

Mario Angelo Pagano, Elena Tibaldi, Giulia Calabretto, Antonella Teramo, Luca Dell'Amico, Gabriella Donà, Gregorio Barilà, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Valentina Trimarco, Monica Facco, Francesco Piazza, Gianpietro Semenzato, Anna Maria Brunati, Renato Zambello
Journal: Blood
Blood (2019) 134 (Supplement_1): 2798.
https://doi.org/10.1182/blood-2019-129883
Published: 2019
Journal Articles

Trial in Progress: Feasibility and Validation Study of the LSC17 Score in Acute Myeloid Leukemia Patients

Tracy Murphy, MDFRCP,FRCPath, Stanley W.K. Ng, PhD, Tong Zhang, Ian King, PhD, Andrea Arruda, Jaime O. Claudio, PhD, Narmin Ibrahimova, Fiona Ferrera, Chantal Rockwell, Zhibin Lu, Natalie Stickle, Carl Virtanen, MSc, Brian Leber, MD, Mitchell Sabloff, MD, Mark D. Minden, MD PhD, Tracy L. Stockley, PhD FCCMG, FACMG, Steven M Chan, MD PhD, Jean C.Y. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2682.
https://doi.org/10.1182/blood-2019-130532
Published: 2019
Journal Articles

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Xiuli Wang, PhD, Miriam Walter, Ryan Urak, Laura Lim, Vibhuti Vyas, MS, Sally Mokhtari, PhD, Don J. Diamond, PhD, Angelo Cardoso, PhD, John Zaia, MD, Stephen J. Forman, MD, Ryotaro Nakamura, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3247.
https://doi.org/10.1182/blood-2019-131843
Published: 2019
Journal Articles

Inter-Cell Networking Profiling Enables Comprehensive Characterization of Immune-Mediated Activity of Anti-CD38 Therapy through Ex-Vivo Analysis of Multiple Myeloma Patients

Alice Bettelli, MS, Rita Ruggiano, Silvia Bocchi, Laura Rocchi, PhD, Andrea Faenza, PhD, Enrica Borsi, Carolina Terragna, Elena Zamagni, MD, Marina Martello, Marco Bettelli, Laura Rambelli, Viviana Guadagnuolo, Nicola Pecorari, Luca Giulianelli, Matteo Pisani, Dario Biscarini, Michele Cavo, Roberto Guerrieri, Massimo Bocchi, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3372.
https://doi.org/10.1182/blood-2019-126894
Published: 2019
Journal Articles

Expression of Notch Pathway Components in Primary Samples of Allogeneic Hematopoietic Cell Transplant Patients with Chronic Graft Versus Host Disease

Marcos Paulo Colella, MD, Fernanda Soares Niemann, MSc, Beatriz Corey Morini, Matheus Lopes, PhD, Francisco José Penteado Aranha, MD PhD, Afonso Celso Vigorito, MD PhD, Sara T Olalla Saad, PhD, Patricia Favaro, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5600.
https://doi.org/10.1182/blood-2019-128785
Published: 2019
Journal Articles

Peripheral Blood Cell Sorting Strategies for Transcriptomic Analysis in Chronic Myelomonocytic Leukemia

Moritz Binder, MDMPH, Ryan Carr, MD PhD, Nathalie Droin, PhD, Abhishek A Mangaonkar, MBBS, Giacomo Coltro, MD, Luciana L Almada, PhD, David Marks, PhD, Kurt Berger, Terra Lasho, PhD, Naseema Gangat, MBBS, Christopher Pin, PhD, Martin Fernandez-Zapico, MD, Eric Solary, MD PhD, Mrinal M Patnaik, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4232.
https://doi.org/10.1182/blood-2019-122187
Published: 2019
Journal Articles

Reduced Number and Function of Endothelial Progenitor Cells in Patients with Beta Thalassemia Major

Galia Spectre, Pinhas Stark, MD, Arza Steimatzky, MD, Pia Raanani, MD, Dorit Lev, PhD, Ran Kornowski, MD, Idit Pazgal, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2247.
https://doi.org/10.1182/blood-2019-129851
Published: 2019