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Journal Articles

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Paul Kerbs, MSc, Johannes Bagnoli, Wolfgang Hiddemann, MD PhD, Wolfgang Enard, PhD, Sebastian Theurich, MD, Philipp A. Greif, MD PD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1453.
https://doi.org/10.1182/blood-2019-128378
Published: 2019
Journal Articles

Inhibition of Fatty Acid Metabolism Re-Sensitizes Resistant Leukemia Stem Cells to Venetoclax with Azacitidine

Courtney L Jones, PhD, Brett M. Stevens, PhD, Rachel Culp-Hill, BS, Angelo Dalessandro, PhD, Anna Krug, BS, Madeline Goosman, Shanshan Pei, PhD, Daniel A Pollyea, MD, Craig T Jordan, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1272.
https://doi.org/10.1182/blood-2019-125773
Published: 2019
Journal Articles

Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells

Harold K. Elias, MD, Christina Spevak, PhD, Lavanya Kannan, PhD, Mohamed A.E. Ali, MD PhD, Gaelle H Martin, PhD, Shanmugapriya Selvaraj, MS, William S Eng, Guangjie Zhao, BS, Amanda Ernlund, PhD, Vinagolu Rajasekhar, PhD, Carolien M Woolthuis, MD PhD, Robert J Schneider, PhD, Christopher Y. Park, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1180.
https://doi.org/10.1182/blood-2019-131333
Published: 2019
Journal Articles

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Hee-Don Chae, PhD, Lara C. Murphy, MD, Michele Donato, PhD, Alex G. Lee, PhD, E. Alejandro Sweet-Cordero, MD PhD, Parveen Abidi, PhD, Henrique Bittencourt, MD PhD, Norman J. Lacayo, MD, Gary Van Houten Dahl, MD, Catherine Aftandilian, MD, Kara L. Davis, DO, Min Huang, PhD, Nathan Sumarsono, BS, Michele Redell, MD PhD, Cecilia H. Fu, MD, I-Ming L. Chen, DVM, MS, Todd A Alonzo, PhD, Elizabeth A. Eklund, MD, Jason R. Gotlib, MD MS, Purvesh Khatri, PhD, Nobuko Hijiya, MD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4246.
https://doi.org/10.1182/blood-2018-99-119974
Published: 2018
Journal Articles

Relapsed Acute Myeloid Leukemia Is Less Sensitive to Venetoclax + Azacitidine Due to Leukemia Stem Cell Resistance Driven By Fatty Acid Metabolism and Can be Overcome By Pharmacologic Inhibition of CPT1

Daniel A Pollyea, MD, Courtney L Jones, PhD, Brett M Stevens, PhD, Shanshan Pei, PhD, Angelo D'Alessandro, PhD, Rachel Culp-Hill, BS, Diana Abbott, PhD, Andrew Hammes, MS, James Dugan, MD, Jonathan A Gutman, MD, Enkhtsetseg Purev, MD PhD, Clayton Smith, MD, Craig T Jordan, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 432.
https://doi.org/10.1182/blood-2018-99-111507
Published: 2018
Journal Articles

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

Alexandra Sipol, Andreas Petry, Erik Hameister, Agnes Görlach, Jürgen Ruland, Stefan Burdach, Poul Sorensen
Journal: Blood
Blood (2018) 132 (Supplement 1): 3888.
https://doi.org/10.1182/blood-2018-99-114014
Published: 2018
Journal Articles

Tissue Resident Memory Cells

Thomas S Kupper, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-5.
https://doi.org/10.1182/blood-2018-99-109534
Published: 2018
Journal Articles

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Shin Hasegawa, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Hiroki Kato, MD, PhD, Yuki Sato, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, Ritsuko Shimizu, MD PhD, Masayuki Yamamoto, MD PhD, Hideo Harigae, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3781.
https://doi.org/10.1182/blood.V130.Suppl_1.3781.3781
Published: 2017
Journal Articles

Functional SCD1 Is Critical for Acute Lymphoblastic Leukaemia Maintenance in the Central Nervous System

Orianne Olivares, Antony Cousins, Elke Markert, Sergey Tumanov, Gillian Mackay, Jurre Kamphorst, Karen Keeshan, Pawel Herzyk, Eyal Gottlieb, Christina Halsey
Journal: Blood
Blood (2017) 130 (Supplement 1): 2608.
https://doi.org/10.1182/blood.V130.Suppl_1.2608.2608
Published: 2017
Journal Articles

Novel Fatty Acid Oxidation Inhibitor Avocatinb Induces AMPK-Dependent Apoptosis of AML Cells Co-Cultured with BM-Adipocytes

Yoko Tabe, Kazumasa Sekihara, PhD, Kaori Saitoh, Vivian Ruvolo, MS, Takashi Miida, MD PhD, Michael Andreeff, MD PhD, Paul A Spagnuolo, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3947.
https://doi.org/10.1182/blood.V128.22.3947.3947
Published: 2016
Journal Articles

Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia

Lai N Chan, PhD, Daniel Braas, Christian Hurtz, PhD, Seyedmehdi Shojaee, PhD, Behzad Kharabi Masouleh, MD, Huimin Geng, PhD, Thomas Ernst, MD, Andreas Hochhaus, MD, Thomas Graeber, PhD, Markus Muschen, MDPhD
Journal: Blood
Blood (2014) 124 (21): 783.
https://doi.org/10.1182/blood.V124.21.783.783
Published: 2014
Journal Articles

Fatty Acid Metabolism Provides a Potential Therapeutic Target To Treat Graft-Versus-Host Disease

Craig A. Byersdorfer, M.D., Ph.D., Victor Tkachev, Stefanie Goodell, Jacob Swanson, James L.M. Ferrara, M.D., D.Sc.
Journal: Blood
Blood (2013) 122 (21): 2002.
https://doi.org/10.1182/blood.V122.21.2002.2002
Published: 2013
Journal Articles

Targeting The Interactions Of Fatty Acid Metabolism With PI3K/mTOR and MAPK As a Novel Therapeutic Strategy In Diffuse Large B-Cell Lymphoma (DLBCL)

Ravi Dashnamoorthy, PhD, Frederick Lansigan, MD, Wilson L Davis, III, B.S., William B Kinlaw, III, MD, Ronald Gartenhaus, Andrew M Evens, DO, MSc
Journal: Blood
Blood (2013) 122 (21): 5133.
https://doi.org/10.1182/blood.V122.21.5133.5133
Published: 2013
Journal Articles

Fatty Acid Metabolism in Diffuse Large B-Cell Lymphoma (DLBCL): Interaction with Oncogenic Cell Signaling Pathways and the Identification of a Novel Treatment Paradigm.

Ravi Dashnamoorthy, Ph.D., Frederick Lansigan, MD, Wilson L Davis, III, B.S., Nancy Kuemmerle, DO, PhD, William B Kinlaw, III, MD, Andrew M. Evens, DO, MSc
Journal: Blood
Blood (2012) 120 (21): 2711.
https://doi.org/10.1182/blood.V120.21.2711.2711
Published: 2012
Journal Articles

Functional Analysis of FOXO3A Involved in Erythroid Differentiation

Hai Wang, Yadong Yang, Hongzhu QU, Xiuyan Ruan, Zhaojun Zhang, Qian Xiong, Heyuan Qi, George Stamatoyannopoulos, John A. Stamatoyannopoulos, MD, Xiangdong Fang
Journal: Blood
Blood (2012) 120 (21): 4731.
https://doi.org/10.1182/blood.V120.21.4731.4731
Published: 2012
Journal Articles

Functional Enrichment Analysis by David in Transgenic MYCN Zebrafish Model

Li-Jing Shen, Fang-Yuan Chen, Lan-Fang Cao, Yong Zhang, Hua Zhong
Journal: Blood
Blood (2012) 120 (21): 5114.
https://doi.org/10.1182/blood.V120.21.5114.5114
Published: 2012
Journal Articles

Distinct Metabolic Dependency of Normal and Leukemic Cells in a Mouse Model

Rushdia Z. Yusuf, MBBS, MPH, Sanket S. Acharya, BA, MBS, Vionnie Yu, PhD, Borja Saez, PhD, Mildred Duvet, Elizabeth Scadden, BA, Gohar Warraich, Clary Clish, PhD, Michael Churchill, BS, John Doench, PhD, David J. Logan, PhD, Colleen Cook, BA, Sudeshna Das, PhD, Adam Brown, PhD, Stephen M. Sykes, Shrikanta Chattopadhyay, MD, Anne E. Carpenter, PhD, Mathew Vander Heiden, MD, PhD, Scott A. Armstrong, MD, PhD, Siddhartha Mukherjee, MD, PhD, Benjamin L. Ebert, MD, D.Phil, David T. Scadden, MD
Journal: Blood
Blood (2011) 118 (21): 759.
https://doi.org/10.1182/blood.V118.21.759.759
Published: 2011
Journal Articles

Targeting Anaplerotic Pathways That Support Fatty Acid Metabolism as a Therapeutic Strategy for Hematological Malignancies: The Achilles’ Heel of the Warburg Effect.

Ismael J. Samudio, PhD, Michael Fiegl, PhD, Marina Konopleva, MD, PhD, Kumar Kaluarachchi, PhD, John S. McMurray, PhD, BS, Borys Korchin, Karen Clise Dwyer, PhD, Romain Harmancey, PhD, Patrick Guthrie, BS, Heinrich Taegtmeyer, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1631.
https://doi.org/10.1182/blood.V112.11.1631.1631
Published: 2008