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Journal Articles

Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus

Robert Silasi, Ravi S. Keshari, Girija Regmi, Cristina Lupu, Constantin Georgescu, Joe H. Simmons, Michael Wallisch, Tia C. L. Kohs, Joseph J. Shatzel, Sven R. Olson, Christina U. Lorentz, Cristina Puy, Erik I. Tucker, David Gailani, Sidney Strickland, András Gruber, Owen J. T. McCarty, Florea Lupu

Blood (2021) 138 (2): 178–189.

https://doi.org/10.1182/blood.2020009345

Published: 2021

Includes: Supplemental data

Journal Articles

Protease activity in single-chain prekallikrein

Ivan Ivanov, Ingrid M. Verhamme, Mao-fu Sun, Bassem Mohammed, Qiufang Cheng, Anton Matafonov, S. Kent Dickeson, Kusumam Joseph, Allen P. Kaplan, David Gailani

Blood (2020) 135 (8): 558–567.

https://doi.org/10.1182/blood.2019002224

Published: 2020

Includes: Supplemental data

Journal Articles

Host and Tumor Factor XII Drive Ovarian Cancer Maintenance and Progression

Evi X Stavrou, MD, Kara L. Bane, M.Sc., Peronne Joseph, M.Sc., Anil Belur Nagaraj, PhD, Analisa Difeo, PhD

Blood (2019) 134 (Supplement_1): 2384.

https://doi.org/10.1182/blood-2019-125862

Published: 2019

Journal Articles

Factor XII Deficiency in ECMO Patients

Katherine Regling, DO, Sarah Ramiz, MD, Meera B. Chitlur, MD

Blood (2019) 134 (Supplement_1): 4965.

https://doi.org/10.1182/blood-2019-131614

Published: 2019

Journal Articles

Age-Associated Changes of Coagulation Test and Coagulation Factor Activities in Healthy Chinese Children

Min Zhou, Xiaobo Luo, Qing Zhang, Xiaolan Yang, Xiaojing Li, Renchi Yang, MD

Blood (2019) 134 (Supplement_1): 4924.

https://doi.org/10.1182/blood-2019-123175

Published: 2019

Journal Articles

Regulation of Coagulation by Polyphosphate

Nicola J. Mutch, BSc, PhD

Blood (2019) 134 (Supplement_1): SCI-18.

https://doi.org/10.1182/blood-2019-121062

Published: 2019

Journal Articles

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Steven de Maat, Wariya Sanrattana, Reiner K. Mailer, Naomi M. J. Parr, Martin Hessing, Robert M. Koetsier, Joost C. M. Meijers, Gerard Pasterkamp, Thomas Renné, Coen Maas

Blood (2019) 134 (19): 1658–1669.

https://doi.org/10.1182/blood.2019000481

Published: 2019

Includes: Supplemental data

Journal Articles

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani

Blood (2019) 133 (10): 1152–1163.

https://doi.org/10.1182/blood-2018-06-860270

Published: 2019

Includes: Supplemental data

Journal Articles

Exosome Polyphosphate Mediates the Activation of FXII By Cancer Cell-Derived Exosomes

Dewen You, PhD, Suman Kundu, MBA, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith R. McCrae, MD

Blood (2018) 132 (Supplement 1): 3800.

https://doi.org/10.1182/blood-2018-99-117308

Published: 2018

Journal Articles

Coagulation Factor XII Plays an Important Role in Procoagulant Activity of Apoptotic Cells

Aizhen Yang, Yi Wu, MD PhD

Blood (2018) 132 (Supplement 1): 2457.

https://doi.org/10.1182/blood-2018-99-118223

Published: 2018

Journal Articles

Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways

Narcis I. Popescu, Robert Silasi, Ravi S. Keshari, Alanson Girton, Tarea Burgett, Sacha S. Zeerleder, David Gailani, Andras Gruber, Florea Lupu, K. Mark Coggeshall

Blood (2018) 132 (8): 849–860.

https://doi.org/10.1182/blood-2017-10-813618

Published: 2018

Includes: Supplemental data

Journal Articles

Heestermans M, Salloum-Asfar S, Salvatori D, Laghmani EH, Luken BM, Zeerleder SS, Spronk HMH, Korporaal SJ, Wagenaar GTM, Reitsma PH, van Vlijmen BJM. Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice. Blood . 2016;127(21):2630-2637.

Blood (2018) 131 (26): 2996.

https://doi.org/10.1182/blood-2018-05-854596

Published: 2018

Journal Articles

Coagulation factor XII in thrombosis and inflammation

Coen Maas, Thomas Renné

Blood (2018) 131 (17): 1903–1909.

https://doi.org/10.1182/blood-2017-04-569111

Published: 2018

Journal Articles

The Anti-Factor XII Antibody AB052 Is Antithrombotic without Hemostatic Impairment in a Primate Model of Extracorporeal Membrane Oxygenation

Michael Wallisch, PhD, Erik I Tucker, PhD, Christina U Lorentz, PhD, Jennifer Johnson, RLATG, Marschelle R Carris, BA, Owen JT McCarty, PhD, Monica T Hinds, PhD, András Gruber, MD

Blood (2017) 130 (Supplement 1): 236.

https://doi.org/10.1182/blood.V130.Suppl_1.236.236

Published: 2017

Journal Articles

Comparison of FXII Activation in Human Plasma By Extracellular Vesicles from Cancer Cells Versus Non-Transformed Cells

Dewen You, PhD, Victor Chatterjee, MD, Suman Kundu, MBA, Mohamed Samour, MBBS, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 3705.

https://doi.org/10.1182/blood.V130.Suppl_1.3705.3705

Published: 2017

Journal Articles

Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice

Zu-Lin Chen, Alexey S. Revenko, Pradeep Singh, A. Robert MacLeod, Erin H. Norris, Sidney Strickland

Blood (2017) 129 (18): 2547–2556.

https://doi.org/10.1182/blood-2016-11-753202

Published: 2017

Includes: Supplemental data

Journal Articles

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Qiufang Cheng, S. Kent Dickeson, Ingrid M. Verhamme, Jonas Emsley, David Gailani

Blood (2017) 129 (11): 1527–1537.

https://doi.org/10.1182/blood-2016-10-744110

Published: 2017

Includes: Supplemental data

Journal Articles

Contact ignition by single-chain XIIa

Joost C. M. Meijers, Alvin H. Schmaier

Blood (2017) 129 (11): 1411–1412.

https://doi.org/10.1182/blood-2017-02-763532

Published: 2017

Journal Articles

Emerging anticoagulant strategies

James C. Fredenburgh, Peter L. Gross, Jeffrey I. Weitz

Blood (2017) 129 (2): 147–154.

https://doi.org/10.1182/blood-2016-09-692996

Published: 2017

Journal Articles

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

Pavan K. Bendapudi, MD, Karen Deceunynck, PhD, Secil Koseoglu, PhD, Roelof Hendrik Bekendam, MD, Shauna D Mason, Jon Kenniston, Robert C. Flaumenhaft, MD PhD

Blood (2016) 128 (22): 258.

https://doi.org/10.1182/blood.V128.22.258.258

Published: 2016

NARROW

Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus

Protease activity in single-chain prekallikrein

Host and Tumor Factor XII Drive Ovarian Cancer Maintenance and Progression

Factor XII Deficiency in ECMO Patients

Age-Associated Changes of Coagulation Test and Coagulation Factor Activities in Healthy Chinese Children

Regulation of Coagulation by Polyphosphate

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Exosome Polyphosphate Mediates the Activation of FXII By Cancer Cell-Derived Exosomes

Coagulation Factor XII Plays an Important Role in Procoagulant Activity of Apoptotic Cells

Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways

Heestermans M, Salloum-Asfar S, Salvatori D, Laghmani EH, Luken BM, Zeerleder SS, Spronk HMH, Korporaal SJ, Wagenaar GTM, Reitsma PH, van Vlijmen BJM. Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice. Blood . 2016;127(21):2630-2637.

Coagulation factor XII in thrombosis and inflammation

The Anti-Factor XII Antibody AB052 Is Antithrombotic without Hemostatic Impairment in a Primate Model of Extracorporeal Membrane Oxygenation

Comparison of FXII Activation in Human Plasma By Extracellular Vesicles from Cancer Cells Versus Non-Transformed Cells

Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Contact ignition by single-chain XIIa

Emerging anticoagulant strategies

Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure

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American Society of Hematology

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American Society of Hematology

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