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Journal Articles

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Stevan P. Tofovic, Edwin K. Jackson, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 2266.

https://doi.org/10.1182/blood-2019-130882

Published: 2019

Journal Articles

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Meixian Huang, Amit Verma, MBBS, Ke Zeng, MD PhD, Mi-Ae Lyu, PhD, Mitsutaka Nishimoto, MD PhD, Hongbing Ma, MD PhD, Zheng Yin, PhD, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 4446.

https://doi.org/10.1182/blood-2019-131948

Published: 2019

Journal Articles

Ectonucleosidase CD39 Is Highly Expressed on ATLL Cells and Suppresses the Immune Response through the Adenosine Pathway

Yasuhiro Nagate, MD, Sachiko Ezoe, MD PhD, Jiro Fujita, MD PhD, Takafumi Yokota, MD PhD, Michiko Ichii, MD PhD, Akira Tanimura, Yukiko Doi, Tomoaki Ueda, Jun Toda, MD, Hirohiko Shibayama, MD PhD, Kenji Oritani, MD PhD, Yuzuru Kanakura, MD PhD

Blood (2018) 132 (Supplement 1): 3720.

https://doi.org/10.1182/blood-2018-99-118555

Published: 2018

Journal Articles

Extracellular ATP and CD39 Regulates Mitochondrial Function and Cytarabine Resistance through Intrinsic PKA-ATF-PGC1a Pathway in Acute Myeloid Leukemia

Jean-Emmanuel Sarry, PhD, Christian Recher, MD PhD, Nesrine Aroua, PhD

Blood (2018) 132 (Supplement 1): 2737.

https://doi.org/10.1182/blood-2018-99-112534

Published: 2018

Journal Articles

The Role of CD39/CD73/Ado/A2AR Axis and HIF-1α in Chronic Lymphocytic Leukemia

Yiqing Cai, Lili Feng, MD PhD, Dai Yuan, MD, Qian Wang, Xin Wang, MD PhD

Blood (2018) 132 (Supplement 1): 4406.

https://doi.org/10.1182/blood-2018-99-115732

Published: 2018

Journal Articles

Novel Evidence That the Ectonucleotidases CD39 and CD73, Which Are Expressed on Hematopoietic Stem/Progenitor Cells (HSPCs), Regulate Mobilization and Homing - Studies in CD39-/- and CD73-/- Mice and with Small-Molecule CD39 and CD73 Inhibitors

Mateusz Adamiak, PhD, Kamila Bujko, MS, Anna Lenkiewicz, PhD, Magdalena Kucia, PhD DSci, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSci

Blood (2018) 132 (Supplement 1): 2060.

https://doi.org/10.1182/blood-2018-99-110631

Published: 2018

Journal Articles

Evaluation of T Cell Compartment By Mass Cytometry Reveals Distinct Patterns of Expression of Exhaustion Markers in Chronic Lymphocytic Leukemia

Blood (2017) 130 (Supplement 1): 4283.

https://doi.org/10.1182/blood.V130.Suppl_1.4283.4283

Published: 2017

Journal Articles

Exploring the Cord Blood T Cell Compartment with Mass Cytometry Reveals the Existence of Memory CD4, CD8 and Regulatory T Cell Pools in the Fetal Period

Muharrem Muftuoglu, MD, Li Li, MD, Juan Jimenez, BS, Duncan Mak, BSc, MPhil, Jared K Burks, PhD, Bingqian Hu, MS, Hila Shaim, MD, Nobuhiko Imahashi, MD PhD, Francesca Lorraine Wei Inng Lim, MD, Pinaki P Banerjee, PhD, Mustafa H Bdiwi, MD, Lucila Nassif Kerbauy, MD, Mecit Kaplan, BS, Darius Armstrong James, MD, Richard E Champlin, MD, Elizabeth J Shpall, MD, Katayoun Rezvani, MD PhD

Blood (2017) 130 (Supplement 1): 4467.

https://doi.org/10.1182/blood.V130.Suppl_1.4467.4467

Published: 2017

Journal Articles

CD39 and CD73 Activity Are Protective in a Mouse Model of Antiphospholipid Antibody-Induced Miscarriage

Harshal Nandurkar, MDPhD, Anushka Samudra, MSc, Karen Dwyer, MBBS, PhD FRACP, Carly Selan, BSc, Sussana Freddi, Mandana Nikpour, Michael Hickey, Karlheinz Peter, Simon Robson, Maithili Sashindranath, Peter Cowan

Blood (2017) 130 (Supplement 1): 459.

https://doi.org/10.1182/blood.V130.Suppl_1.459.459

Published: 2017

Journal Articles

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

Tiziana Vaisitti, PhD, Sara Serra, PhD, Cinzia Bologna, PhD, Nicoletta Vitale, PhD, Stefania Gobessi, PhD BS, Dimitar G Efremov, MD PhD, Silvia Deaglio, MD

Blood (2017) 130 (Supplement 1): 1721.

https://doi.org/10.1182/blood.V130.Suppl_1.1721.1721

Published: 2017

Journal Articles

Acute Myeloid Leukemia (AML) Blasts Influence the Gene Expression Signature and Co-Signaling Receptor Expression of CD8 + T Cells

Hanna A. Knaus, MD, Sofia Berglund, MD PhD, Hubert Hackl, PhD, Raúl Montiel-Esparza, MD, Mark J. Levis, MD PhD, Judith E Karp, MD, Ivana Gojo, MD, Leo Luznik, MD

Blood (2016) 128 (22): 1700.

https://doi.org/10.1182/blood.V128.22.1700.1700

Published: 2016

Journal Articles

High-Throughput Characterization and New Insight into the Role of Tumor Associated Macrophages (TAMs) in Multiple Myeloma (MM)

Paula Arana, Aintzane Zabaleta, Marta Lasa, Patricia Maiso, PhD, Diego Alignani, Tomas Jelinek, MD, Victor Segura, PhD, Wouter van den Bossche, Cristina Teodosio, Daniela Damasceno, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, Joan Bladé, Jacques J.M. van Dongen, MD PhD, Jesus San Miguel, MD PhD, Alberto Orfao, MD PhD, Bruno Paiva, PhD

Blood (2016) 128 (22): 482.

https://doi.org/10.1182/blood.V128.22.482.482

Published: 2016

Journal Articles

Maturation and Phenotypic Diversity of Human CD4 + Regulatory T Cells in Umbilical Cord Blood and Peripheral Blood from Healthy Donors

Tiago R Matos, MD MSc, Hongye Liu, Masahiro Hirakawa, MD PhD, Ana Cristina Alho, MD, Jerome Ritz, MD

Blood (2015) 126 (23): 2357.

https://doi.org/10.1182/blood.V126.23.2357.2357

Published: 2015

Journal Articles

Activated Human iNKT Cells in Pediatric Sickle Cell Disease Patients and in Culture Upregulate Ectonucleotidase CD39 and Adenosine a 2A Receptor

Jennifer C. Yu, MD, Gene W. Lin, MD PhD, Jenny Kim, MD, Joel Linden, PhD

Blood (2014) 124 (21): 2734.

https://doi.org/10.1182/blood.V124.21.2734.2734

Published: 2014

Journal Articles

Kindlin-2 regulates hemostasis by controlling endothelial cell–surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism

Elzbieta Pluskota, Yi Ma, Kamila M. Bledzka, Katarzyna Bialkowska, Dmitry A. Soloviev, Dorota Szpak, Eugene A. Podrez, Paul L. Fox, Stanley L. Hazen, James J. Dowling, Yan-Qing Ma, Edward F. Plow

Blood (2013) 122 (14): 2491–2499.

https://doi.org/10.1182/blood-2013-04-497669

Published: 2013

Includes: Supplemental data

Journal Articles

TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses

Heather B. Cohen, Katharine T. Briggs, John P. Marino, Katya Ravid, Simon C. Robson, David M. Mosser

Blood (2013) 122 (11): 1935–1945.

https://doi.org/10.1182/blood-2013-04-496216

Published: 2013

Includes: Supplemental data

Journal Articles

Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?

Jan David Hohmann, Xiaowei Wang, Stefanie Krajewski, Carly Selan, Carolyn A. Haller, Andreas Straub, Elliot L. Chaikof, Harshal H. Nandurkar, Christoph E. Hagemeyer, Karlheinz Peter

Blood (2013) 121 (16): 3067–3075.

https://doi.org/10.1182/blood-2012-08-449694

Published: 2013

Includes: Supplemental data

Journal Articles

CD39 target practice

Debra K. Newman

Blood (2013) 121 (16): 3061–3062.

https://doi.org/10.1182/blood-2013-02-484469

Published: 2013

Journal Articles

Platelet Reactivity and CD39 Ectonucleotidase Activities in Cryptogenic Stroke

Aaron J Marcus, MD, Joan HF Drosopoulos, PhD, Kim E Olson, MD, Ranjini Anand, MS, Dana Leifer, MD, Jorge R Kizer, MD

Blood (2012) 120 (21): 3397.

https://doi.org/10.1182/blood.V120.21.3397.3397

Published: 2012

Journal Articles

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Aisha V. Sauer, Immacolata Brigida, Nicola Carriglio, Raisa Jofra Hernandez, Samantha Scaramuzza, Daniela Clavenna, Francesca Sanvito, Pietro L. Poliani, Nicola Gagliani, Filippo Carlucci, Antonella Tabucchi, Maria Grazia Roncarolo, Elisabetta Traggiai, Anna Villa, Alessandro Aiuti

Blood (2012) 119 (6): 1428–1439.

https://doi.org/10.1182/blood-2011-07-366781

Published: 2012

Includes: Supplemental data

NARROW

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Ectonucleosidase CD39 Is Highly Expressed on ATLL Cells and Suppresses the Immune Response through the Adenosine Pathway

Extracellular ATP and CD39 Regulates Mitochondrial Function and Cytarabine Resistance through Intrinsic PKA-ATF-PGC1a Pathway in Acute Myeloid Leukemia

The Role of CD39/CD73/Ado/A2AR Axis and HIF-1α in Chronic Lymphocytic Leukemia

Novel Evidence That the Ectonucleotidases CD39 and CD73, Which Are Expressed on Hematopoietic Stem/Progenitor Cells (HSPCs), Regulate Mobilization and Homing - Studies in CD39-/- and CD73-/- Mice and with Small-Molecule CD39 and CD73 Inhibitors

Evaluation of T Cell Compartment By Mass Cytometry Reveals Distinct Patterns of Expression of Exhaustion Markers in Chronic Lymphocytic Leukemia

Exploring the Cord Blood T Cell Compartment with Mass Cytometry Reveals the Existence of Memory CD4, CD8 and Regulatory T Cell Pools in the Fetal Period

CD39 and CD73 Activity Are Protective in a Mouse Model of Antiphospholipid Antibody-Induced Miscarriage

Hyper-Activation of the Adenosinergic Axis in the Eμ-TCL1 Chronic Lymphocytic Leukemia Mouse Model Offers Therapeutic Opportunities

Acute Myeloid Leukemia (AML) Blasts Influence the Gene Expression Signature and Co-Signaling Receptor Expression of CD8 + T Cells

High-Throughput Characterization and New Insight into the Role of Tumor Associated Macrophages (TAMs) in Multiple Myeloma (MM)

Maturation and Phenotypic Diversity of Human CD4 + Regulatory T Cells in Umbilical Cord Blood and Peripheral Blood from Healthy Donors

Activated Human iNKT Cells in Pediatric Sickle Cell Disease Patients and in Culture Upregulate Ectonucleotidase CD39 and Adenosine a 2A Receptor

Kindlin-2 regulates hemostasis by controlling endothelial cell–surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism

TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses

Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?

CD39 target practice

Platelet Reactivity and CD39 Ectonucleotidase Activities in Cryptogenic Stroke

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

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American Society of Hematology

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American Society of Hematology

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