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Journal Articles

HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation

Dijiong Wu, MD, Man Li, PhD, Lianjun Zhang, PhD, Jing Qi, PhD, Chun-Wei David Chen, PhD, Xin He, PhD, Yinghui Zhu, PhD, Haojie Dong, PhD, Jie Sun, PhD, Ling Li, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 642.
https://doi.org/10.1182/blood-2019-124134
Published: 2019
Journal Articles

Fatal Dysfunction and Fragmentation of Thrombin-Stimulated Platelets

Oleg V. Kim, PhD, Tatiana A. Nevzorova, PhD, Elmira R. Mordakhanova, Izabella A. Andrianova, Giang Le Minh, Mark S. Alber, PhD, Olga Vagin, PhD, Rustem I. Litvinov, MD PhD, John W. Weisel, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 521.
https://doi.org/10.1182/blood-2018-99-112703
Published: 2018
Journal Articles

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Xin He, PhD, Yinghui Zhu, PhD, Haojie Dong, PhD, Sierra Min Li, Zonghui Ding, PhD, Jie Sun, PhD, Juan Du, MDPhD, Hanying Wang, PhD, Lianjun Zhang, PhD, Yudao Shen, PhD, Hairui Su, BS, PhD, Samer K. Khaled, MD, Dandan Zhao, MD, Lei Zhang, PhD, Robert Hickey, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Xinyang Zhao, PhD, Jian Jin, PhD, Nadia Carlesso, MD PhD, Jianjun Chen, PhD, Yang Xu, MD, Guido Marcucci, Ling Li, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 760.
https://doi.org/10.1182/blood-2018-99-112766
Published: 2018
Journal Articles

Ruxolitinib-Induced Defects in DNA Repair Cause Sensitivity to PARP Inhibitors in Myeloproliferative Neoplasms

Margaret Nieborowska-Skorska, Silvia Maifrede, Yashodhara Dasgupta, Katherine Sullivan, Bac Viet Le, Martyna Solecka, Lucia Kubovcakova, Morgan Nawrocki, Martin Kirschner, MD, Huaqing Zhao, Josef T. Prchal, MD, Katarzyna Piwocka, Alison R. Moliterno, MD, Steffen Koschmieder, Anthony R Green, PhD FRCP, FRCPath, FMedSci, Radek C. Skoda, MD, Tomasz Skorski
Journal: Blood
Blood (2017) 130 (Supplement 1): 2938.
https://doi.org/10.1182/blood.V130.Suppl_1.2938.2938
Published: 2017
Journal Articles

Dasatinib Enhances Targeting of Human AML Leukemia Stem Cells by Chemotherapeutic Agents Via Activation of p53

Cedric Dos Santos, Ph.D, Tinisha McDonald, YinWei Ho, Liu Hongjun, Allen Lin, Stephen J Forman, MD, Kuo Ya-Huei, Ph.D, Ravi Bhatia, MD
Journal: Blood
Blood (2012) 120 (21): 3590.
https://doi.org/10.1182/blood.V120.21.3590.3590
Published: 2012
Journal Articles

Cytoprotective Autophagy Induction by Imatinib Mesylate In Non-BCR-ABL Expressing Cells

Keisuke Miyazawa, MD, PhD, Tadashi Ohtomo, Shota Moriya, Munekazu Naito, MD, PhD, Masahiko Kuroda, MD, PhD, Masahiro Itoh, MD, PhD, Akio Tomoda, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 4937.
https://doi.org/10.1182/blood.V116.21.4937.4937
Published: 2010
Journal Articles

Enhanced Elimination of 6-Mercaptopurine or Methotrexate-Treated Acute Lymphoblastic Leukemia Cells by Natural Killer Lymphocytes In Vitro: A Potential Mechanism of Action of Maintenance Chemotherapy

Abdual H. Siddiqui, MBBS, MD, Mohammad Bhuiyan, MD, PhD, Akila Muthukumar, MD, Steven Buck, Yaddanapudi Ravindranath, MD, Sureyya Savasan, MD
Journal: Blood
Blood (2010) 116 (21): 2128.
https://doi.org/10.1182/blood.V116.21.2128.2128
Published: 2010
Journal Articles

Towards Effective Immunotherapy of Multiple Myeloma: Enhanced Elimination of Myeloma Cells by Combination of Lenalidomide with the Human CD38 Monoclonal Antibody Daratumumab

Michael S. van der Veer, Michel de Weers, Berris van Kessel, Shulamiet Wittebol, Joost M Bakker, Paul W.H.I. Parren, Henk M Lokhorst, Tuna Mutis, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3059.
https://doi.org/10.1182/blood.V116.21.3059.3059
Published: 2010
Journal Articles

Role of the SIRT1 Deacetylase in Survival and Imatinib Resistance of CML CD34+ Progenitors.

Ling Li, PhD, Liang Li, MD, PhD, Hongfeng Yuan, PhD, Wenyong Chen, PhD, Ravi Bhatia, MD
Journal: Blood
Blood (2009) 114 (22): 189.
https://doi.org/10.1182/blood.V114.22.189.189
Published: 2009
Journal Articles

Cell Cycle Entry Potentiates Elimination of Chemotherapy-Resistant Human AML Stem Cells.

Yoriko Saito, MD, Naoyuki Uchida, MD, PhD, Satoshi Tanaka, Mariko Tomizawa-Murasawa, Nahoko Suzuki, Shinsuke Takagi, MD, Yuho Najima, MD, Yuki Aoki, MD, Akiko Sone, Atsushi Wake, MD, Shuichi Taniguchi, MD, PhD, Leonard D. Shultz, PhD, Fumihiko Ishikawa, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1422.
https://doi.org/10.1182/blood.V114.22.1422.1422
Published: 2009
Journal Articles

Treatment with Pegylated Interferon Alpha 2a in Combination with the Bcl-Xl Inhibitor ABT-737 Specifically Targets JAK2V617F Positive Hematopoietic Progenitor Cells From Patients with Polycythemia Vera.

Min Lu, PhD, Wei Zhang, Daniel Yoo, Dmitriy Berenzon, Yan Li, Xiaoli Wang, MD, PhD, Adam Austin, John Mascarenhas, MD, Mingjiang Xu, MD, PhD, Ronald Hoffman, MD
Journal: Blood
Blood (2009) 114 (22): 3916.
https://doi.org/10.1182/blood.V114.22.3916.3916
Published: 2009