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Journal Articles

Alterations of Gut Microbiome Accelerate Multiple Myeloma Progression By Increasing the Relative Abundances of Nitrogen Recycling Bacteria

Xingxing Jian, PhD, Yinghong Zhu, Jian Ouyang, Qian Lei, Jiliang Xia, PhD, Jingyu Zhang, Jiaojiao Guo, Jinuo Wang, MD, Jingchao Lin, Mingming Su, Yongjun Guan, Guancheng Li, PhD, Minghua Wu, PhD, Jian Li, MD, Juanjuan Xiang, PhD, Lu Xie, PhD, Lugui Qiu, MD PhD, Wei Jia, PhD, Wen Zhou, PhD

Blood (2019) 134 (Supplement_1): 688.

https://doi.org/10.1182/blood-2019-125051

Published: 2019

Journal Articles

Pilot Study of Telmisartan (Micardis) for Prevention of Acute Graft Vs. Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation: Interim Analysis

Sujatha Iyengar, PhD, Scott D. Rowley, MD, Caixin Zhan, Michele L. Donato, MD, Themba Nyirenda, PhD, David H. Schwartz, MD PhD

Blood (2019) 134 (Supplement_1): 4546.

https://doi.org/10.1182/blood-2019-129378

Published: 2019

Journal Articles

Hematopoietic Phf6 Deletion in Mice Causes HSC Depletion and Expansion of Myeloid Progenitors

Roman Verner, Gabrielle Ochoco, Patrick Somers, Cristian Taborda, Vikram R Paralkar, MD

Blood (2018) 132 (Supplement 1): 3829.

https://doi.org/10.1182/blood-2018-99-120041

Published: 2018

Journal Articles

Inhibition of ATR Potentiates Acute Myeloid Leukemia Cells to the RNA Pol I Transcription Inhibitor CX-5461

Margaret Shatara, MD, Tingting Wang, Xinyu Li, Holly Edwards, BS, Jeffrey W. Taub, MD, Hai Lin, MD, Yubin Ge, PhD

Blood (2018) 132 (Supplement 1): 5224.

https://doi.org/10.1182/blood-2018-99-113937

Published: 2018

Journal Articles

Novel Combination Therapy Targeting rDNA Transcription and Histone Deacetylation Provides Effective Treatment for Multiple Myeloma, and Synergises in Bortezomib-Resistant MM

Kylee H Maclachlan, BSc, MBChB, FRACP, FRCPA, Andrew Cuddihy, PhD, Nadine Hein, PhD, Carleen Cullinane, PhD, Simon J. Harrison, MBBS,MRCP,FRCPath,FRACP,PhD, Ross Hannan, PhD, Gretchen Poortinga, PhD

Blood (2018) 132 (Supplement 1): 1945.

https://doi.org/10.1182/blood-2018-99-113765

Published: 2018

Journal Articles

Novel Combination Therapies with the RNA Polymerase I Inhibitor CX-5461 Significantly Improve Efficacy in Multiple Myeloma

Kylee H Maclachlan, FRACP,FRCPA, Andrew Cuddihy, PhD, Nadine Hein, PhD, Carleen Cullinane, PhD, Simon J. Harrison, MBBS,MRCP,FRCPath,FRACP,PhD, Ross Hannan, PhD, Gretchen Poortinga, PhD

Blood (2017) 130 (Supplement 1): 1805.

https://doi.org/10.1182/blood.V130.Suppl_1.1805.1805

Published: 2017

Journal Articles

Differences in Fecal Microbiota in Long-Term Adolscent/Young Adult Hodgkin Lymphoma Survivors and Their Unaffected Twins

Nancy Huang, PhD, Amie Hwang, PhD MPH, Venu Lagishetty, PhD, Marta Epeldegui, PhD, M.S., Yang Yu, M.S., Laura Buchanan, R.N., Guoqin Yu, PhD, Bharat N. Nathwani, MD, Josh Millstein, PhD, Thomas M. Mack, MD, M.P.H., Otoniel Martinez-Maza, PhD, Jonathan Jacobs, MD, PhD, Wendy Cozen, DO,MPH

Blood (2017) 130 (Supplement 1): 4084.

https://doi.org/10.1182/blood.V130.Suppl_1.4084.4084

Published: 2017

Journal Articles

Microbial Exposure Regulates the Development of Anti-Blood Group Antibodies

Connie M. Arthur, PhD, Harold Clifford Sullivan, MD, Christian Gerner-Smidt, Nourine Ahmed-Kamili, Ashley Bennett, Seema R. Patel, PhD, Steve Henry, Sean R. Stowell, MD PhD

Blood (2016) 128 (22): 20.

https://doi.org/10.1182/blood.V128.22.20.20

Published: 2016

Journal Articles

Chronic Transfusion and Iron Overload Modify the Mouse Gut Microbiome

Francesca La Carpia, PhD, Boguslaw Wojczyk, PhD, Abdelhadi Rebbaa, PhD, Amy Tang, MD BS, Eldad A. Hod, MD

Blood (2016) 128 (22): 200.

https://doi.org/10.1182/blood.V128.22.200.200

Published: 2016

Journal Articles

Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1

Le Xuan Truong Nguyen, Yunqin Lee, Lenore Urbani, Paul J. Utz, Anne W. Hamburger, John B. Sunwoo, Beverly S. Mitchell

Blood (2015) 125 (16): 2519–2529.

https://doi.org/10.1182/blood-2014-12-616433

Published: 2015

Includes: Supplemental data

Journal Articles

Lenalidomide Induced Degradation of Aiolos Disrupts RNA Polimerase I Activity and Ribosomal Biogenesis in Myeloma Cells

Ines Tagoug, PhD, Jiri Slaby, MD, Paola E. Neri, MD PhD, Justin Simms, Jackie Babich, Ranjan Maity, PhD, Li Ren, PhD, Howie Wu, Nizar J Bahlis, MD

Blood (2014) 124 (21): 3422.

https://doi.org/10.1182/blood.V124.21.3422.3422

Published: 2014

Journal Articles

Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells

Le Xuan Truong Nguyen, Steven M. Chan, Tri Duc Ngo, Aparna Raval, Kyeong Kyu Kim, Ravindra Majeti, Beverly S. Mitchell

Blood (2014) 124 (4): 579–589.

https://doi.org/10.1182/blood-2013-12-544726

Published: 2014

Includes: Supplemental data

Journal Articles

Activation Of Akt Enhances Ribosomal RNA Synthesis In AML Cells Through a Novel Isoform Of TIF-1A and Inhibition Of Filamin A Cleavage

Le Xuan Truong Nguyen, PhD, Min Huang, Steven M. Chan, MD, PhD, Ravi Majeti, MD, PhD, Beverly S. Mitchell

Blood (2013) 122 (21): 1266.

https://doi.org/10.1182/blood.V122.21.1266.1266

Published: 2013

Journal Articles

Reduced rRNA expression and increased rDNA promoter methylation in CD34 + cells of patients with myelodysplastic syndromes

Aparna Raval, Kunju J. Sridhar, Shripa Patel, Brit B. Turnbull, Peter L. Greenberg, Beverly S. Mitchell

Blood (2012) 120 (24): 4812–4818.

https://doi.org/10.1182/blood-2012-04-423111

Published: 2012

Includes: Supplemental data

Journal Articles

Increased γH2AX Foci in Old Hematopoietic Stem Cells Are Independent of the DNA Damage Response and Linked to Inefficient DNA Replication/Transcription

Johanna Flach, Sietske Bakker, PhD, Pauline Conroy, Damien Reynaud, PhD, Michelle M. Le Beau, PhD, Ciaran Morrison, PhD, Emmanuelle Passegué, PhD

Blood (2012) 120 (21): 1207.

https://doi.org/10.1182/blood.V120.21.1207.1207

Published: 2012

Journal Articles

Identification of Novel Fusion Genes with 28S Ribosomal DNA in Hematologic Malignancies

Satoru Kobayashi, Tomohiko Taki, MD, PhD, Hisao Nagoshi, MD, Yoshiaki Chinen, MD, Yuichi Yokokawa, MD, Hirokazu Kanegane, MD, PhD, Yosuke Matsumoto, MD, PhD, Junya Kuroda, MD, PhD, Shigeo Horiike, MD, PhD, Kazuhiro Nishida, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2012) 120 (21): 4418.

https://doi.org/10.1182/blood.V120.21.4418.4418

Published: 2012

Journal Articles

Relationship Between Intestinal Marginal Zone B-Cell Lymphoma and Enterobacterias Including Camphylobacter Jejuni

Sung Yong Oh, Won Seog Kim, Seok Jin Kim, MD, PhD, Junshik Hong, Soon Il Lee, Jae Hoon Lee, MD, Young Rok Do, M.D., Min Kyung Kim, Ho Sup Lee, Cheolwon Suh, MD, Seong Yoon Yi, Jong Hyun KIm, sook Hee Hong

Blood (2011) 118 (21): 5224.

https://doi.org/10.1182/blood.V118.21.5224.5224

Published: 2011

Journal Articles

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias

Nadine Hein, PhD, Megan J Bywater, PhD, Kim Stanley, BSc, Inge Verbrugge, PhD, Carlene Cullinane, PhD, Adele Baker, PhD, Hannes Zuber, PhD, Amy Rappaport, PhD, Denis Drygin, PhD, Nanni Huser, PhD, Josh Bliesath, PhD, David M Ryckman, PhD, William G Rice, PhD, Scott W Lowe, PhD, Ricky W Johnstone, PhD, Richard B Pearson, PhD, Grant A. McArthur, MD, PhD, FRACP, MBBS, Ross D Hannan, PhD

Blood (2011) 118 (21): 1548.

https://doi.org/10.1182/blood.V118.21.1548.1548

Published: 2011

Journal Articles

Ribosomal RNA Expression In CD34+ Hematopoietic Progenitor Cells Inversely Correlates with Ribosomal DNA Methylation In Myelodysplastic Syndromes.

Aparna Raval, PhD, Daniel A Pollyea, MD, Kunju J Shridhar, PhD, Shripa Patel, Peter L. Greenberg, MD, Beverly S. Mitchell, MD

Blood (2010) 116 (21): 1682.

https://doi.org/10.1182/blood.V116.21.1682.1682

Published: 2010

Journal Articles

Utility of PCR Amplification and DNA Microarray Hybridization in 16S rDNA for Rapid Diagnosis of Bacteremia Associated with Hematological Malignancies.

Eiju Negoro, Hiromichi Iwasaki, MD, PhD, Katunori Tai, Satoshi Ikegaya, Mitsunobu Shimadzu, Ph.D., Takanori Ueda, MD, PhD

Blood (2009) 114 (22): 1635.

https://doi.org/10.1182/blood.V114.22.1635.1635

Published: 2009

NARROW

Alterations of Gut Microbiome Accelerate Multiple Myeloma Progression By Increasing the Relative Abundances of Nitrogen Recycling Bacteria

Pilot Study of Telmisartan (Micardis) for Prevention of Acute Graft Vs. Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation: Interim Analysis

Hematopoietic Phf6 Deletion in Mice Causes HSC Depletion and Expansion of Myeloid Progenitors

Inhibition of ATR Potentiates Acute Myeloid Leukemia Cells to the RNA Pol I Transcription Inhibitor CX-5461

Novel Combination Therapy Targeting rDNA Transcription and Histone Deacetylation Provides Effective Treatment for Multiple Myeloma, and Synergises in Bortezomib-Resistant MM

Novel Combination Therapies with the RNA Polymerase I Inhibitor CX-5461 Significantly Improve Efficacy in Multiple Myeloma

Differences in Fecal Microbiota in Long-Term Adolscent/Young Adult Hodgkin Lymphoma Survivors and Their Unaffected Twins

Microbial Exposure Regulates the Development of Anti-Blood Group Antibodies

Chronic Transfusion and Iron Overload Modify the Mouse Gut Microbiome

Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1

Lenalidomide Induced Degradation of Aiolos Disrupts RNA Polimerase I Activity and Ribosomal Biogenesis in Myeloma Cells

Interaction of TIF-90 and filamin A in the regulation of rRNA synthesis in leukemic cells

Activation Of Akt Enhances Ribosomal RNA Synthesis In AML Cells Through a Novel Isoform Of TIF-1A and Inhibition Of Filamin A Cleavage

Reduced rRNA expression and increased rDNA promoter methylation in CD34 + cells of patients with myelodysplastic syndromes

Increased γH2AX Foci in Old Hematopoietic Stem Cells Are Independent of the DNA Damage Response and Linked to Inefficient DNA Replication/Transcription

Identification of Novel Fusion Genes with 28S Ribosomal DNA in Hematologic Malignancies

Relationship Between Intestinal Marginal Zone B-Cell Lymphoma and Enterobacterias Including Camphylobacter Jejuni

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias

Ribosomal RNA Expression In CD34+ Hematopoietic Progenitor Cells Inversely Correlates with Ribosomal DNA Methylation In Myelodysplastic Syndromes.

Utility of PCR Amplification and DNA Microarray Hybridization in 16S rDNA for Rapid Diagnosis of Bacteremia Associated with Hematological Malignancies.

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American Society of Hematology

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American Society of Hematology

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