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Journal Articles

Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2

Laura J. Braun, Rebekka I. Stegmeyer, Kerstin Schäfer, Stefan Volkery, Silke M. Currie, Birgit Kempe, Astrid F. Nottebaum, Dietmar Vestweber

Blood (2020) 136 (5): 627–639.

https://doi.org/10.1182/blood.2019003442

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

TNF-Induced Vaso-Occlusive and Inflammatory Processes in Mice with Sickle Cell Anemia Are Abrogated By the Platelet Activation Inhibitor, Prasugrel

Hanan Chweih, M.Sc., Juliete A.F. Silva, PhD, Erica M.F. Gotardo, PhD, Pamela L. Brito, B.Sc, Guilherme G.O. Barbosa, PhD, Flavia Garcia, PhD, Wilson A. Ferreira, Jr., PhD, Flavia C. Leonardo, PhD, Carla F. Franco-Penteado, PhD, Fernando F. Costa, MD, PhD, Nicola Conran, PhD

Blood (2018) 132 (Supplement 1): 2354.

https://doi.org/10.1182/blood-2018-99-118633

Published: 2018

Journal Articles

Tannic Acid Inhibits Protein Disulfide Isomerase, Platelet Activation and Thrombus Formation

Li Zhu, MD PhD

Blood (2018) 132 (Supplement 1): 2418.

https://doi.org/10.1182/blood-2018-99-114418

Published: 2018

Journal Articles

The Ribonucleotide Reductase Inhibitor, Didox, Reduces the In Vivo Vascular Inflammation and Oxidative Stress Induced By Acute Hemolysis

Nicola Conran, PhD, Juliete A.F. Silva, PhD, Erica M.F. Gotardo, PhD, Hanan Chweih, M.Sc., Lediana I. Miguel, M.Sc., Flávia Costa Leonardo, PhD, Wilson A. Ferreira, Jr., PhD, Bo E. Hedlund, PhD, Howard L. Elford, PhD, Fernando F. Costa, MD, PhD

Blood (2018) 132 (Supplement 1): 1034.

https://doi.org/10.1182/blood-2018-99-119224

Published: 2018

Journal Articles

The Clinical-Stage sGC Stimulator IW-1701 Prevents Increase of Plasma Biomarkers of Intravascular Inflammation and Suppresses Leukocyte-Endothelial Interactions in Tnfα-Treated Mice

Boris Tchernychev, Susanne Feil, Peter Germano, William Warren, Elisabeth Lonie, Robert Feil, Todd G Milne, John Hadcock, Yueh-Tyng Chien, Mark G Currie, Regina Margaret Graul

Blood (2017) 130 (Supplement 1): 447.

https://doi.org/10.1182/blood.V130.Suppl_1.447.447

Published: 2017

Journal Articles

Rock Inhibitor Fasudil Reduces Leukocyte-Endothelium Interactions in the Microvasculature of a Sickle Cell Mouse Model of Allergic Inflammation

Athos Rodrigues Moraes, Hanan Chweih, BSc, Nicola Conran, PhD, Kleber Yotsumoto Fertrin, MD PhD, Fernando Ferreira Costa, MD PhD, Carla Fernanda Franco-Penteado, BSc, PhD

Blood (2017) 130 (Supplement 1): 961.

https://doi.org/10.1182/blood.V130.Suppl_1.961.961

Published: 2017

Journal Articles

Chronic Administration of the PDE9 Inhibitor PF-04447943 Reduces Leukocyte-Platelet Aggregates and Markers of Endothelial Activation in a Mouse Model of Sickle Cell Disease

Reema Jasuja, Elizabeth Parks, John E. Murphy, Debra D Pittman

Blood (2016) 128 (22): 1293.

https://doi.org/10.1182/blood.V128.22.1293.1293

Published: 2016

Journal Articles

Therapeutic Activity of Peg Albumin in Transgenic Mouse Model of Sickle Cell Disease Is a Function of the Pattern of Pegylation

Devendra Lingojwar, PhD, Savita Bhutoria, PhD, Fantao Meng, PhD, Sangeetha Thangaswamy, PhD, Henny H Billett, MD, Caterina Minniti, MD, Amy Tsai, PhD, Marcos Intaglietta, PhD, Craig A Branch, PhD, Seetharama A Acharya, PhD

Blood (2016) 128 (22): 4848.

https://doi.org/10.1182/blood.V128.22.4848.4848

Published: 2016

Journal Articles

The Endothelin Receptor Etb Plays a Crucial Role for Recruitment of Neutrophils to the Vascular Wall in Sickle Cell Disease

Bérengere Koehl, MD, Pierre Nivoit, PhD, Wassim El Nemer, PhD, Catia Pereira, Valentine Brousse, MD, Lea Guyonnet, Anna Chipont, Olivia Lenoir, Malika Benkerrou, MD, Yves Colin Aronovicz, PhD, Pierre-Louis Tharaux, Caroline Le Van Kim, PhD

Blood (2016) 128 (22): 857.

https://doi.org/10.1182/blood.V128.22.857.857

Published: 2016

Journal Articles

Platelet Surface PDI Controls the Ligand-Binding Function of Glycoprotein Ibalpha and Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

Kyungho Kim, PhD, Jing Li, PhD, Robert K Andrews, PhD, Joyce Chiu, PhD, Philip Hogg, PhD, Jaehyung Cho, PhD

Blood (2015) 126 (23): 235.

https://doi.org/10.1182/blood.V126.23.235.235

Published: 2015

Journal Articles

Co-Administration of Hydroxyurea and a Specific AKT2 Inhibitor Has Beneficial Effects on Acute Vaso-Occlusive Events and Survival in Sickle Cell Disease Mice

Jing Li, PhD, Andrew Barazia, Kyungho Kim, PhD, Jaehyung Cho, PhD

Blood (2015) 126 (23): 3383.

https://doi.org/10.1182/blood.V126.23.3383.3383

Published: 2015

Journal Articles

Therapeutic Efficacy of Semisynthetic Supra Perfusion Resuscitation Fluids, EAF Peg Alb and EAF Peg Hb, Are Differentiated By Their Cerebral Effects in Animal Models of Sickle Cell Disease

Craig A Branch, MS, PhD, Min-Hui Cui, PhD, Sangeetha Thangaswamy, PhD, Nicholas Branch, Seetharama Acharya

Blood (2015) 126 (23): 773.

https://doi.org/10.1182/blood.V126.23.773.773

Published: 2015

Journal Articles

Neutrophil DREAM Is a Novel Regulator for Beta2 Integrin Function through NF-Kappab Signaling and Modulates Neutrophil Recruitment during Vascular Inflammation

Andrew Barazia, Jing Li, PhD, Kyungho Kim, PhD, Chinnaswamy Tiruppathi, PhD, Jaehyung Cho, PhD

Blood (2015) 126 (23): 888.

https://doi.org/10.1182/blood.V126.23.888.888

Published: 2015

Journal Articles

PDE-9 Inhibition Combined with Hydroxyurea Is Beneficial in Vaso-Occlusive Crisis in Mouse Model of Sickle Cell Disease

Reema Jasuja, Sunita Patel Hett, Joachim Fruebis, PhD, Debra Pittman

Blood (2014) 124 (21): 2694.

https://doi.org/10.1182/blood.V124.21.2694.2694

Published: 2014

Journal Articles

Thrombus Structure Regulates Plasma Loss after Vascular Injury in Vivo

John Douglas Welsh, Joshua P Taliaferro, Timothy J. Stalker, PhD, Scott L. Diamond, PhD, Lawrence F. Brass, MD PhD

Blood (2014) 124 (21): 4162.

https://doi.org/10.1182/blood.V124.21.4162.4162

Published: 2014

Journal Articles

Therapeutic Amelioration of Vaso-Occlusion and Blood Flow Impairment in Transgenic Sickle Mice By the Antioxidant Flavonoid Quercetin

Sangeetha Thangaswamy, PhD, Henny H Billett, MD, Craig A. Branch, PhD, Sandra M. Suzuka, M.S., Seetharama A Acharya, PhD

Blood (2014) 124 (21): 4054.

https://doi.org/10.1182/blood.V124.21.4054.4054

Published: 2014

Journal Articles

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue

Max Lerchenberger, Bernd Uhl, Konstantin Stark, Gabriele Zuchtriegel, Annekathrin Eckart, Meike Miller, Daniel Puhr-Westerheide, Marc Praetner, Markus Rehberg, Alexander G. Khandoga, Kirsten Lauber, Steffen Massberg, Fritz Krombach, Christoph A. Reichel

Blood (2013) 122 (5): 770–780.

https://doi.org/10.1182/blood-2012-12-472944

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

In Vivo Interrogation of a Human Von Willebrand Type A Domain.

Thomas Diacovo, MD, Hairu Zhou, MSc, Jianchun Chen, PhD

Blood (2012) 120 (21): 2176.

https://doi.org/10.1182/blood.V120.21.2176.2176

Published: 2012

Journal Articles

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Valerie Tutwiler, Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent M. Hayes, Sergei V. Zaytsev, PhD, X. Long Zheng, MD, PhD, Douglas B. Cines, MD, Steven E. McKenzie, MD, PhD, John W. Weisel, Ph.D., Mortimer Poncz, MD, Lubica Rauova, MD, PhD

Blood (2012) 120 (21): 635.

https://doi.org/10.1182/blood.V120.21.635.635

Published: 2012

Journal Articles

Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands

Won Ho Yang, Claudia Nussbaum, Prabhjit K. Grewal, Jamey D. Marth, Markus Sperandio

Blood (2012) 120 (5): 1015–1026.

https://doi.org/10.1182/blood-2012-04-424366

Published: 2012

Includes: Supplemental data

NARROW

Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2

TNF-Induced Vaso-Occlusive and Inflammatory Processes in Mice with Sickle Cell Anemia Are Abrogated By the Platelet Activation Inhibitor, Prasugrel

Tannic Acid Inhibits Protein Disulfide Isomerase, Platelet Activation and Thrombus Formation

The Ribonucleotide Reductase Inhibitor, Didox, Reduces the In Vivo Vascular Inflammation and Oxidative Stress Induced By Acute Hemolysis

The Clinical-Stage sGC Stimulator IW-1701 Prevents Increase of Plasma Biomarkers of Intravascular Inflammation and Suppresses Leukocyte-Endothelial Interactions in Tnfα-Treated Mice

Rock Inhibitor Fasudil Reduces Leukocyte-Endothelium Interactions in the Microvasculature of a Sickle Cell Mouse Model of Allergic Inflammation

Chronic Administration of the PDE9 Inhibitor PF-04447943 Reduces Leukocyte-Platelet Aggregates and Markers of Endothelial Activation in a Mouse Model of Sickle Cell Disease

Therapeutic Activity of Peg Albumin in Transgenic Mouse Model of Sickle Cell Disease Is a Function of the Pattern of Pegylation

The Endothelin Receptor Etb Plays a Crucial Role for Recruitment of Neutrophils to the Vascular Wall in Sickle Cell Disease

Platelet Surface PDI Controls the Ligand-Binding Function of Glycoprotein Ibalpha and Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

Co-Administration of Hydroxyurea and a Specific AKT2 Inhibitor Has Beneficial Effects on Acute Vaso-Occlusive Events and Survival in Sickle Cell Disease Mice

Therapeutic Efficacy of Semisynthetic Supra Perfusion Resuscitation Fluids, EAF Peg Alb and EAF Peg Hb, Are Differentiated By Their Cerebral Effects in Animal Models of Sickle Cell Disease

Neutrophil DREAM Is a Novel Regulator for Beta2 Integrin Function through NF-Kappab Signaling and Modulates Neutrophil Recruitment during Vascular Inflammation

PDE-9 Inhibition Combined with Hydroxyurea Is Beneficial in Vaso-Occlusive Crisis in Mouse Model of Sickle Cell Disease

Thrombus Structure Regulates Plasma Loss after Vascular Injury in Vivo

Therapeutic Amelioration of Vaso-Occlusion and Blood Flow Impairment in Transgenic Sickle Mice By the Antioxidant Flavonoid Quercetin

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue

In Vivo Interrogation of a Human Von Willebrand Type A Domain.

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands

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American Society of Hematology

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American Society of Hematology

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