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Journal Articles

AML onco-niche: villain or ally?

Marta Derecka

Blood (2021) 138 (7): 504–506.

https://doi.org/10.1182/blood.2021012299

Published: 2021

Journal Articles

Circulating Extracellular Vesicles from Patients with Sickle Cell Disease Progressively Disrupt Different Types of Endothelial Intercellular Junctions

Gabrielle Lapping-Carr, MD, Joanna Gemel, PhD, Yifan Mao, Eric C. Beyer, MD PhD

Blood (2019) 134 (Supplement_1): 4823.

https://doi.org/10.1182/blood-2019-123268

Published: 2019

Journal Articles

Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation

Abhishek K Singh, PhD, Karin Golan, PhD, Mark J Althoff, BS, Ekaterina Petrovich-Kopitman, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Mayla Bertagna, MSc, Daniel Gonzalez-Nieto, PhD, Luis C Barrio, MD PhD, Tsvee Lapidot, PhD, Jose A Cancelas, MD PhD

Blood (2018) 132 (Supplement 1): 872.

https://doi.org/10.1182/blood-2018-99-118292

Published: 2018

Journal Articles

Connexin-43 Is a Negative Regulator of Mitochondrial Fission, Mitophagy and Apoptosis of Dividing Hematopoietic Stem Cells through the Drp1-Pink1 Axis

Blood (2018) 132 (Supplement 1): 639.

https://doi.org/10.1182/blood-2018-99-118663

Published: 2018

Journal Articles

Efficient Delivery of Antiapoptotic Signals from Marrow Stromal Cells to Acute Lymphoblastic Leukemia Cells Is Associated with Differential Expression of Genes Related to the Membrane and to Regulation of Apoptosis and Is Dependent in Part on Gap Junction Function

Craig A. Mullen, MD PhD, Sana Usmani, DO, Leti Nunez, BS, Olena Tkachenko, MD

Blood (2016) 128 (22): 5066.

https://doi.org/10.1182/blood.V128.22.5066.5066

Published: 2016

Journal Articles

Mitochondria Transfer from Hematopoietic Stem and Progenitor Cells to Pdgfrα + /Sca-1 - /CD48 dim BM Stromal Cells Via CX43 Gap Junctions and AMPK Signaling Inversely Regulate ROS Generation in Both Cell Populations

Karin Golan, PhD, Ashley Wellendorf, Yuji Takihara, MD PhD, Anju Kumari, PhD, Eman Khatib-Massalha, Msc, Orit Kollet, PhD, Hui Cheng, PhD, Tao Cheng, MD, Mark J. Althoff, Shiri Gur-Cohen, PhD, Tomer Itkin, PhD, Marie-Dominique Fillipi, PhD, Jose A Cancelas, MD PhD, Toshio Suda, MD PhD, Tsvee Lapidot, PhD

Blood (2016) 128 (22): 5.

https://doi.org/10.1182/blood.V128.22.5.5

Published: 2016

Journal Articles

PPAR-γ Agonists Induce Growth Arrest of Kit/AML1-ETO Leukemia Cells Acting on Diverse Pathways

Valter Agosti, MD PhD, Daniela Talarico, Agostina Urzino, Raghavendra Vasudeva Murthi, PhD, Aurora Anna Rita Nocera, PhD, Emilia Dora Giovannone

Blood (2014) 124 (21): 5211.

https://doi.org/10.1182/blood.V124.21.5211.5211

Published: 2014

Journal Articles

Deletion Of Core Binding Factors Runx1 and Runx2 Leads To Perturbed Hematopoiesis In Multiple Lineages

John Anto Pulikkan, PhD, Xue Liting, Rachel Gerstein, PhD, Merav Socolovsky, PhD, Lucio H. Castilla, PhD

Blood (2013) 122 (21): 46.

https://doi.org/10.1182/blood.V122.21.46.46

Published: 2013

Journal Articles

Hematopoietic Stem Cells and Their BM Stromal Microenvironment Share a Dynamic Inverse Metabolic State During Quiescence and Proliferation Via ROS Transfer Between The Two Populations

Karin Golan, MSc, Aya Ludin, DMD, PhD, Tomer Itkin, PhD, Shiri Cohen-Gur, MSc, Orit Kollet, PhD, Xin-Jiang Lu, PhD, Alexander Kalinkovich, MD, PhD, Maria Maryanovich, PhD, Atan Gross, PhD, Tsvee Lapidot, PhD

Blood (2013) 122 (21): 587.

https://doi.org/10.1182/blood.V122.21.587.587

Published: 2013

Journal Articles

Hyperangiotensinemia Induces Stem Cell/Progenitor Mobilization and De-Adhesion From BM Endothelial Cells Through AT2R Signaling and Inhibition of RhoA Activity

Kyung-Hee Chang, PhD, Ramesh C Nayak, Ph.D., Katie Bezold, Ashley Ficker, Swarnava Roy, PhD, Xuan Zhou, Megan Pirman, Susan Dunn, Yi Zheng, PhD, Punam Malik, MD, Jose A. Cancelas, M.D. PhD

Blood (2012) 120 (21): 3466.

https://doi.org/10.1182/blood.V120.21.3466.3466

Published: 2012

Journal Articles

Osteolineage Connexin 43 Expression Is Required for Stromal Support of Leukemic Stem Cells in Vitro and in Vivo

Julia Tasset, Ashley Ficker, Susan Dunn, Jose A. Cancelas, M.D. PhD.

Blood (2012) 120 (21): 4090.

https://doi.org/10.1182/blood.V120.21.4090.4090

Published: 2012

Journal Articles

Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors

Daniel Gonzalez-Nieto, Lina Li, Anja Kohler, Gabriel Ghiaur, Eri Ishikawa, Amitava Sengupta, Malav Madhu, Jorden L. Arnett, Rebecca A. Santho, Susan K. Dunn, Glenn I. Fishman, David E. Gutstein, Roberto Civitelli, Luis C. Barrio, Matthias Gunzer, Jose A. Cancelas

Blood (2012) 119 (22): 5144–5154.

https://doi.org/10.1182/blood-2011-07-368506

Published: 2012

Includes: Supplemental data

Journal Articles

ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet ‘Favorable' Genetic Category

Blood (2011) 118 (21): 417.

https://doi.org/10.1182/blood.V118.21.417.417

Published: 2011

Journal Articles

Single Nucleotide Polymorphism Array (SNP-A) Genomic Profiling of Mantle Cell Lymphoma (MCL) Against a Large Control Database Reveals Recurring Copy Number Alterations (CNAs) and Copy Neutral Loss of Heterozygosity (CN-LOH)

Michael J. Rauh, MD, PhD, Juraj Bodo, MD, Eric Hsi, MD, Bill Richendollar, Yuka Sugimoto, MD, PhD, Jaroslaw P Maciejewski, MD, PhD, FACP, Christine L. O'Keefe, PhD, Stephen D. Smith, MD

Blood (2010) 116 (21): 2001.

https://doi.org/10.1182/blood.V116.21.2001.2001

Published: 2010

Journal Articles

Connexin Expression by Human Primary AML Cells

Brynjar Foss, MSc, PhD, Lars Rune Sæterdal, Anita Ryningen, Anne M. Øyan, Øystein Bruserud

Blood (2010) 116 (21): 2147.

https://doi.org/10.1182/blood.V116.21.2147.2147

Published: 2010

Journal Articles

Connexin-43 Regulates the Cell Cycle Entry of Hematopoietic Stem Cells within the Stem Cell Niche.

Daniel Gonzalez-Nieto, PhD, Gabriel Ghiaur, MD, PhD, Lina Li, DDS, PhD, Jorden Arnett, Susan Dunn, Glenn Fishman, MD, David Gutstein, Roberto Civitelli, Jose Cancelas, MD, PhD

Blood (2009) 114 (22): 1500.

https://doi.org/10.1182/blood.V114.22.1500.1500

Published: 2009

Journal Articles

Connexin-43 Expression Regulates the Migration of Hematopoietic Stem Cells and Progenitors towards and From Bone Marrow.

Daniel Gonzalez-Nieto, PhD, Kyung-Hee Chang, PhD, Anja Koehler, Jorden Arnett, Susan Dunn, Lina Li, DDS, PhD, Gabriel Ghiaur, MD, PhD, Amitava Sengupta, PhD, Glenn Fishman, MD, David Gutstein, MD, PhD, Roberto Civitelli, MD, Luis Barrio, MD, PhD, Matthias Gunzer, PhD, Jose Cancelas, MD, PhD

Blood (2009) 114 (22): 562.

https://doi.org/10.1182/blood.V114.22.562.562

Published: 2009

Journal Articles

Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

Keishi Otsu, Shonit Das, Sandra D. Houser, Sadiqa K. Quadri, Sunita Bhattacharya, Jahar Bhattacharya

Blood (2009) 113 (18): 4197–4205.

https://doi.org/10.1182/blood-2008-09-176198

Published: 2009

Includes: Supplemental data

Journal Articles

Functional SDF-1 Secretion from BM Stromal Cells Is a Cell Contact-Dependent Event Mediated by Cx43 and Cx45 Gap-Junctions

Amir Schajnovitz, MSc, Tomer Itkin, MSc, Aya Ludin, DMD, MSc, Alexander Kalinkovich, MD, PhD, Kfir Lapid, MSc, Rony Seger, PhD, Tsvee Lapidot, PhD

Blood (2008) 112 (11): 319.

https://doi.org/10.1182/blood.V112.11.319.319

Published: 2008

Journal Articles

N-Cadherin and Cadherin-11 Play Vital Roles in the Cell-Cell Contact between Hematopoietic Progenitor Cells and Mesenchymal Stromal Cells.

Wolfgang Wagner, MD, PhD, Frederik Wein, Anke Diehlmann, Rainer Saffrich, PhD, Patrick Wuchter, MD, Christoph Roderburg, MD, Volker Eckstein, PhD, Anthony D. Ho, MD

Blood (2007) 110 (11): 1406.

https://doi.org/10.1182/blood.V110.11.1406.1406

Published: 2007

NARROW

AML onco-niche: villain or ally?

Circulating Extracellular Vesicles from Patients with Sickle Cell Disease Progressively Disrupt Different Types of Endothelial Intercellular Junctions

Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation

Connexin-43 Is a Negative Regulator of Mitochondrial Fission, Mitophagy and Apoptosis of Dividing Hematopoietic Stem Cells through the Drp1-Pink1 Axis

Efficient Delivery of Antiapoptotic Signals from Marrow Stromal Cells to Acute Lymphoblastic Leukemia Cells Is Associated with Differential Expression of Genes Related to the Membrane and to Regulation of Apoptosis and Is Dependent in Part on Gap Junction Function

Mitochondria Transfer from Hematopoietic Stem and Progenitor Cells to Pdgfrα + /Sca-1 - /CD48 dim BM Stromal Cells Via CX43 Gap Junctions and AMPK Signaling Inversely Regulate ROS Generation in Both Cell Populations

PPAR-γ Agonists Induce Growth Arrest of Kit/AML1-ETO Leukemia Cells Acting on Diverse Pathways

Deletion Of Core Binding Factors Runx1 and Runx2 Leads To Perturbed Hematopoiesis In Multiple Lineages

Hematopoietic Stem Cells and Their BM Stromal Microenvironment Share a Dynamic Inverse Metabolic State During Quiescence and Proliferation Via ROS Transfer Between The Two Populations

Hyperangiotensinemia Induces Stem Cell/Progenitor Mobilization and De-Adhesion From BM Endothelial Cells Through AT2R Signaling and Inhibition of RhoA Activity

Osteolineage Connexin 43 Expression Is Required for Stromal Support of Leukemic Stem Cells in Vitro and in Vivo

Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors

ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet ‘Favorable' Genetic Category

Single Nucleotide Polymorphism Array (SNP-A) Genomic Profiling of Mantle Cell Lymphoma (MCL) Against a Large Control Database Reveals Recurring Copy Number Alterations (CNAs) and Copy Neutral Loss of Heterozygosity (CN-LOH)

Connexin Expression by Human Primary AML Cells

Connexin-43 Regulates the Cell Cycle Entry of Hematopoietic Stem Cells within the Stem Cell Niche.

Connexin-43 Expression Regulates the Migration of Hematopoietic Stem Cells and Progenitors towards and From Bone Marrow.

Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

Functional SDF-1 Secretion from BM Stromal Cells Is a Cell Contact-Dependent Event Mediated by Cx43 and Cx45 Gap-Junctions

N-Cadherin and Cadherin-11 Play Vital Roles in the Cell-Cell Contact between Hematopoietic Progenitor Cells and Mesenchymal Stromal Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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