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Journal Articles

CD3-Activating Bi-Specific Antibody Targeting CD19 on B Cells in Mono- and Bi-Valent Format

Yumin CUI, PhD, Zhihua Huang, MSc, Xinfeng Zhang, PhD, Wuzhong Shen, MSc, Hanyang Chen, PhD, Zaiqing Wen, PhD, Bo Qi, MSc, Lan Luo, MSc, Ying Tan, Yun Wu, PhD, Ada Kung, PhD, Xiaoqiang Yan, PhD

Blood (2018) 132 (Supplement 1): 4169.

https://doi.org/10.1182/blood-2018-99-112819

Published: 2018

Journal Articles

Patients with CD3G mutations reveal a role for human CD3γ in T reg diversity and suppressive function

Jared H. Rowe, Ottavia M. Delmonte, Sevgi Keles, Brian D. Stadinski, Adam K. Dobbs, Lauren A. Henderson, Yasuhiro Yamazaki, Luis M. Allende, Francisco A. Bonilla, Luis I. Gonzalez-Granado, Seyma Celikbilek Celik, Sukru N. Guner, Hasan Kapakli, Christina Yee, Sung-Yun Pai, Eric S. Huseby, Ismail Reisli, Jose R. Regueiro, Luigi D. Notarangelo

Blood (2018) 131 (21): 2335–2344.

https://doi.org/10.1182/blood-2018-02-835561

Published: 2018

Includes: Supplemental data

Journal Articles

A ROR1 Bispecific T Cell Engager for the Treatment of Chronic Lymphocytic Leukaemia Demonstrates Enhanced Function Following Ibrutinib Treatment

Satyen Gohil, BSc, MBBS, MRCP, FRCPath, Solange Rosa Paredes-Moscosso, Micaela Harrasser, Mohamed El-Kholy, Emma Morris, FRCPath, MA, MBBChir, PhD MRCP, Amit Nathwani, MD PhD, Marco Della Peruta, PhD

Blood (2017) 130 (Supplement 1): 4316.

https://doi.org/10.1182/blood.V130.Suppl_1.4316.4316

Published: 2017

Journal Articles

Targeting T-Cell Malignancies with Chimeric Antigen Receptors Using Two Structurally Different Antigen Binding Domains Against CD5

Sunil S Raikar, MD, Lauren C Fleischer, Robert Moot, B.S., Na Yoon Paik, B.S., Kristopher Knight, B.S., Christopher B Doering, PhD, H. Trent Spencer, PhD

Blood (2017) 130 (Supplement 1): 4462.

https://doi.org/10.1182/blood.V130.Suppl_1.4462.4462

Published: 2017

Journal Articles

Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing

Mark J. Osborn, PhD, Beau R Webber, PhD, Friederike Knipping, Cara-lin Lonetree, Anthony DeFeo, Amber McElroy, Colby Starker, PhD, Richard Gabriel, Sarah Merkel, Keli L. Hippen, PhD, Daniel Voytas, PhD, Christof von Kalle, MD, Manfred Schmidt, PhD, Jeffrey S. Miller, MD, Jordan Jarjour, PhD, Alexander Astrakhan, PhD, Andrew M Scharenberg, MD, Jakub Tolar, MD, PhD, Bruce R. Blazar, MD

Blood (2015) 126 (23): 2045.

https://doi.org/10.1182/blood.V126.23.2045.2045

Published: 2015

Journal Articles

Precocious Differentiation of Somatic and Pluripotent Stem Cells Bearing Pre-Arranged TCR

Nicholas Klemen, MD, Raul Vizcardo, PhD, Linda Tran, BS, Nicholas P. Restifo, MD

Blood (2015) 126 (23): 847.

https://doi.org/10.1182/blood.V126.23.847.847

Published: 2015

Journal Articles

MiR-181b in Chronic Lymphocytic Leukemia B Cells Is Regulated By Cellular Interaction with CD4+ T Cells and Increases the CTL Toxicity Versus the Leukemic Clone

Mirco di Marco, PhDstudent, Serena Veschi, Rosa Visone, Giuseppe Leone, Paola Lanuti, Sara Pagotto, PhD, Felice Pepe, Stefania Pacillo, Claudia Curcio, Marco Marchisio, Sebastiano Miscia, Idanna Innocenti, MD, Francesco Autore, Barbara Vannata, Mario Di Gioacchino, Renato Mariani-Costantini, Luca Laurenti, MD, Angelo Veronese

Blood (2015) 126 (23): 4134.

https://doi.org/10.1182/blood.V126.23.4134.4134

Published: 2015

Journal Articles

Development of a Bispecific Antibody-Releasing Stem Cell System for the Eradication of Acute Myeloid Leukemia Blasts Via Redirected Immune Effector Cells

Roberta Aliperta, M.Sc., Marc Cartellieri, PhD, Anja Feldmann, PhD, Claudia Arndt, M.Sc., Stefanie Koristka, M.Sc., Irene Michalk, M.Sc., Martin Bornhäuser, MD, Armin Ehninger, PhD, Gerhard Ehninger, MD, Michael P. Bachmann, PhD

Blood (2014) 124 (21): 4810.

https://doi.org/10.1182/blood.V124.21.4810.4810

Published: 2014

Journal Articles

TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD

Sara Mastaglio, MD, Pietro Genovese, PhD, Zulma Magnani, MSc, Elena Provasi, PhD, Angelo Lombardo, PhD, Andreas Reik, Nicoletta Cieri, MD, Fabio Ciceri, Claudio Bordignon, MD, Michael C. Holmes, PhD, Philip D Gregory, PhD, Luigi Naldini, MD, PhD, Chiara Bonini, MD

Blood (2013) 122 (21): 2898.

https://doi.org/10.1182/blood.V122.21.2898.2898

Published: 2013

Journal Articles

Enhancing The Efficacy and Specificity Of Antibody-Based T Cell Retargeting Strategies Against Hematological Malignancies

Claudia Arndt, M.Sc., Marc Cartellieri, PhD, Roberta Aliperta, M.Sc., Stefanie Koristka, M.Sc., Irene Michalk, M.Sc., Martin Bornhäuser, MD, Gerhard Ehninger, MD, Michael Bachmann, PhD, Anja Feldmann, PhD

Blood (2013) 122 (21): 930.

https://doi.org/10.1182/blood.V122.21.930.930

Published: 2013

Journal Articles

Safe and Effective Re-Induction Of Complete Remissions In Adults With Relapsed B-ALL Using 19-28z CAR CD19-Targeted T Cell Therapy

Blood (2013) 122 (21): 69.

https://doi.org/10.1182/blood.V122.21.69.69

Published: 2013

Journal Articles

Enhancing the Efficacy of T Cell Receptor (TCR) Gene Therapy by Co-Transfer of TCR and Additional CD3 Molecules Into CD4+ T Cells

Emma K Nicholson, MD, Maryam Ahmadi, PhD, Angelika Holler, Rebecca Pike, PhD, Ben Carpenter, MD, Sharyn Thomas, PhD, Sara Ghorashian, MD, Shao-An Xue, PhD, Hans Stauss, MD, PhD, Emma Morris, MD, PhD

Blood (2012) 120 (21): 2044.

https://doi.org/10.1182/blood.V120.21.2044.2044

Published: 2012

Journal Articles

Human Peripheral CD34+ γδ T Cells Can Transdifferentiate into αβ T Cells.

Hendrik Ziegler, Jan Haarer, Marco Sterk, Hans-Georg Rammensee, Prof., Rupert Handgretinger, MD, Karin Schilbach, PhD

Blood (2012) 120 (21): 2312.

https://doi.org/10.1182/blood.V120.21.2312.2312

Published: 2012

Journal Articles

Key Survival Pathways and Chemotherapeutic Sensitivity of Breast Implant Associated Anaplastic Large Cell Lymphomas,

Melissa G Lechner, PhD, Connor Church, Carolina Megiel, Rikki S Bass, Garry S Brody, MD, Alan L. Epstein, MD, PhD

Blood (2011) 118 (21): 3739.

https://doi.org/10.1182/blood.V118.21.3739.3739

Published: 2011

Journal Articles

The Feature of CD3γ, CD3δ and CD3ε Gene Expression in Benzene-Exposed and Benzene- Poisoned Workers

Bo Li, Jing Jing Fan, Jing Ru Wang, Yun Yu Chen, Shao Hua Chen, Li Jian Yang, Yu Wei, Wei Wei Liu, Jia Yu Chen, Yang Qiu Li

Blood (2011) 118 (21): 4929.

https://doi.org/10.1182/blood.V118.21.4929.4929

Published: 2011

Journal Articles

Redirection of Immune Effector Cells by Bispecific Antibody Systems for the Treatment of Acute Myeloid Leukemia

Claudia Arndt, Anja Feldmann, Stefanie Koristka, Irene Michalk, Marc Cartellieri, Slava Stamova, Malte von Bonin, Martin Bornhäuser, MD, Gerhard Ehninger, MD, Michael Bachmann

Blood (2011) 118 (21): 1528.

https://doi.org/10.1182/blood.V118.21.1528.1528

Published: 2011

Journal Articles

TCR expression; quantitative easing by CD3

Helen E. Heslop

Blood (2011) 118 (13): 3452–3453.

https://doi.org/10.1182/blood-2011-08-369025

Published: 2011

Journal Articles

CD3 limits the efficacy of TCR gene therapy in vivo

Maryam Ahmadi, Judith W. King, Shao-An Xue, Cécile Voisine, Angelika Holler, Graham P. Wright, Jonathan Waxman, Emma Morris, Hans J. Stauss

Blood (2011) 118 (13): 3528–3537.

https://doi.org/10.1182/blood-2011-04-346338

Published: 2011

Journal Articles

First Generation Chimeric Antigen Receptor Display Functional Defects In Key Signal Pathways Upon Antigen Stimulation

Johannes Duell, Sarah Lurati, Marcus Dittrich, Tanja Bedke, Martin Pule, Hermann Einsele, MD, Claudia Rossig, MD, Max S Topp

Blood (2010) 116 (21): 2088.

https://doi.org/10.1182/blood.V116.21.2088.2088

Published: 2010

Journal Articles

Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor–CD3 expression in enteropathy-associated T-cell lymphoma

Jennifer M. L. Tjon, Wieke H. M. Verbeek, Yvonne M. C. Kooy-Winkelaar, Binh H. Nguyen, Arno R. van der Slik, Allan Thompson, Mirjam H. M. Heemskerk, Marco W. J. Schreurs, Liesbeth H. A. Dekking, Chris J. Mulder, Jeroen van Bergen, Frits Koning

Blood (2008) 112 (13): 5103–5110.

https://doi.org/10.1182/blood-2008-04-150748

Published: 2008

Includes: Supplemental data

NARROW

CD3-Activating Bi-Specific Antibody Targeting CD19 on B Cells in Mono- and Bi-Valent Format

Patients with CD3G mutations reveal a role for human CD3γ in T reg diversity and suppressive function

A ROR1 Bispecific T Cell Engager for the Treatment of Chronic Lymphocytic Leukaemia Demonstrates Enhanced Function Following Ibrutinib Treatment

Targeting T-Cell Malignancies with Chimeric Antigen Receptors Using Two Structurally Different Antigen Binding Domains Against CD5

Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing

Precocious Differentiation of Somatic and Pluripotent Stem Cells Bearing Pre-Arranged TCR

MiR-181b in Chronic Lymphocytic Leukemia B Cells Is Regulated By Cellular Interaction with CD4+ T Cells and Increases the CTL Toxicity Versus the Leukemic Clone

Development of a Bispecific Antibody-Releasing Stem Cell System for the Eradication of Acute Myeloid Leukemia Blasts Via Redirected Immune Effector Cells

TCR Gene Editing Achieved In a Single Round Of T Cell Activation Is Sufficient To Redirect T Cell Specificity and Prevent GvHD

Enhancing The Efficacy and Specificity Of Antibody-Based T Cell Retargeting Strategies Against Hematological Malignancies

Safe and Effective Re-Induction Of Complete Remissions In Adults With Relapsed B-ALL Using 19-28z CAR CD19-Targeted T Cell Therapy

Enhancing the Efficacy of T Cell Receptor (TCR) Gene Therapy by Co-Transfer of TCR and Additional CD3 Molecules Into CD4+ T Cells

Human Peripheral CD34+ γδ T Cells Can Transdifferentiate into αβ T Cells.

Key Survival Pathways and Chemotherapeutic Sensitivity of Breast Implant Associated Anaplastic Large Cell Lymphomas,

The Feature of CD3γ, CD3δ and CD3ε Gene Expression in Benzene-Exposed and Benzene- Poisoned Workers

Redirection of Immune Effector Cells by Bispecific Antibody Systems for the Treatment of Acute Myeloid Leukemia

TCR expression; quantitative easing by CD3

CD3 limits the efficacy of TCR gene therapy in vivo

First Generation Chimeric Antigen Receptor Display Functional Defects In Key Signal Pathways Upon Antigen Stimulation

Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor–CD3 expression in enteropathy-associated T-cell lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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