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Journal Articles

Management of pyruvate kinase deficiency in children and adults

Free
Rachael F. Grace, Wilma Barcellini
Journal: Blood
Blood (2020) 136 (11): 1241–1249.
https://doi.org/10.1182/blood.2019000945
Published: 2020
Journal Articles

Inhibition of Complement C1s with Sutimlimab in Patients with Cold Agglutinin Disease (CAD): Results from the Phase 3 Cardinal Study

Free
Alexander Röth, Wilma Barcellini, Shirley D'Sa, Yoshitaka Miyakawa, Catherine M Broome, Marc Michel, David J. Kuter, Bernd Jilma, Tor Henrik Anderson Tvedt, Stella Lin, Xiaoyu Jiang, Caroline Reuter, William Hobbs, Sigbjørn Berentsen
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-2.
https://doi.org/10.1182/blood-2019-132490
Published: 2019
Journal Articles

Lactate Dehydrogenase to Carboxyhemoglobin Ratio As a Biomarker of Heme Release to Heme Processing Is Associated with Higher Tricuspid Regurgitant Jet Velocity and Early Death in Sickle Cell Disease

Free
Annelies J. Van Vuren, MD, Laurel Mendelsohn, BS, Richard van Wijk, PhD, Caterina P. Minniti, MD, John Baird, MD, Gregory J Kato, MD, Eduard J. van Beers, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2274.
https://doi.org/10.1182/blood-2019-124048
Published: 2019
Journal Articles

Opioid Analgesics Are Associated with Albuminuria in Adult Patients with Sickle Cell Anemia

Free
Ashley Thrower, BS, Zhou Laura, Vimal K. Derebail, MD, David Wichlan, Ashley Smith, RN, Jianwen Cai, PhD, Kenneth I. Ataga, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2308.
https://doi.org/10.1182/blood-2019-131368
Published: 2019
Journal Articles

Treatment of Delayed Hemolytic Transfusion Reactions in Sickle Cell Disease Patients By an Anti-C5 Antibody

Free
Aline Floch, MD MSc, Alexandre Morel, MD, Fabian Zanchetta-Balint, Catherine Cordonnier-Jourdin, PharmD, Slimane Allali, MD, Maximilien Grall, MD, Ghislaine Ithier, MD, Benjamin Carpentier, MD, Sadaf Pakdaman, Jean-Claude Merle, MD, Radjiv Goulabchand, MD, Tackwa Khalifeh, MD, Ana Berceanu, MD, Christelle Chantalat-Auger, MD, Véronique Frémeaux-Bacchi, MD, Marc Michel, Armand Mekontso-Dessap, MD PhD, Anoosha Habibi, France Pirenne, MD PhD, Pablo Bartolucci, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2458.
https://doi.org/10.1182/blood-2019-127176
Published: 2019
Journal Articles

Pancreatic Iron Deposition Following the Role of Iron Loading Among Transfusion Dependent Sickle Cell Disease Egyptian Children and Young Adults

Free
Mohsen Saleh Elalfy, MD, Khalid Allam, MD, Ahmed Ibrahim, MD, Basant Mosaad, MD, Fatma Soliman Elsayed Ebeid, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4828.
https://doi.org/10.1182/blood-2019-123683
Published: 2019
Journal Articles

Soluble P-Selectin Levels in Patients with Sickle Cell Disease Reflect Platelets' Activation Rather Than Endothelial Dysfunction

Free
Ersi Voskaridou, Mantzou Aimilia, PhD, Pagona Flevari, MD, Maria Dimopoulou, MD, Veroniki Komninaka, MD, Konstantina Repa, MD, Ioannis Papassotiriou, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4829.
https://doi.org/10.1182/blood-2019-122524
Published: 2019
Journal Articles

Symptomatic Bilirubin Gallstones in Patients with PNH Treated with Eculizumab

Free
David J. Araten, MD, H. Leon Pachter, Robert J Dring, Elliot Newman, Steven M Cohen
Journal: Blood
Blood (2019) 134 (Supplement_1): 4795.
https://doi.org/10.1182/blood-2019-124571
Published: 2019
Journal Articles

Paroxysmal Cold Hemoglobinuria Successfully Treated with Complement Inhibition

Free
Sarah A Lau-Braunhut, MD, Hannah Stone, Griffin Collins, MD, Sigbjørn Berentsen, MD PhD, Matt Zinter, MD, Benjamin Braun, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4798.
https://doi.org/10.1182/blood-2019-126365
Published: 2019
Journal Articles

Thrombotic Thrombocytopenia Purpura Case Series in Skmc 2016-2017

Free
Mohamed Abu Haleeqa, MBBS, Hanan Al Raeesi, MBBS, Fatima Alkaabi, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4799.
https://doi.org/10.1182/blood-2019-126479
Published: 2019
Journal Articles

Trial in Progress: Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Global Study of Fostamatinib for the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Free
Nichola Cooper, MD MRCP, Isabel Gorham, BS RN, Ann M. Lowe, MD, Robert P. Numerof, PhD, Sandy Tong, MD, David J. Kuter
Journal: Blood
Blood (2019) 134 (Supplement_1): 4800.
https://doi.org/10.1182/blood-2019-126544
Published: 2019
Journal Articles

Association of Endothelial Biomarkers with Cerebral MRI Perfusion Analysis in Patients with Sickle Cell Disease

Free
Liza Afzali-Hashemi, Lena Vaclavu, PhD, Erfan Nur, MD PhD, Aart J Nederveen, PhD, Bart J. Biemond, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1000.
https://doi.org/10.1182/blood-2019-124688
Published: 2019
Journal Articles

Progression of Albuminuria in Sickle Cell Anemia: A Multicenter, Longitudinal Study

Free
Omar Niss, MD, Adam Lane, PhD, Monika Asnani, PhD, Marianne McPherson Yee, MD MSc, Ashok Raj, Susan E Creary, MD, Courtney D. Fitzhugh, MD, Prasad V. Bodas, MD, Santosh L. Saraf, MD, Sharada Sarnaik, MD, Charles T. Quinn, MD, Prasad Devarajan, MD, Punam Malik, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1004.
https://doi.org/10.1182/blood-2019-125860
Published: 2019
Journal Articles

Updated Results of a Phase II Study of Reduced-Intensity Chemotherapy with Mini-Hyper-CVD in Combination with Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Free
Nicholas J. Short, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD, Xuelin Huang, PhD, Nitin Jain, MD, Koji Sasaki, MD, Rita Khouri, Naval G. Daver, MD, Naveen Pemmaraju, MD, Joseph D. Khoury, MD, Jeffrey L. Jorgensen, MD PhD, Yesid Alvarado, MD, Marina Y Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Tapan M. Kadia, MD, Musa E. Yilmaz, MD, Gautam M. Borthakur, MD, Jan A. Burger, MD PhD, Steven M. Kornblau, MD, William G. Wierda, MD PhD, Courtney D. DiNardo, MD MSc, Alessandra Ferrajoli, MD, Jovitta Jacob, RN, Meagan Rostykus, RN, Rebecca Garris, MSc, Marygrace Ward, RDC, Binru Huang, RDC, Corabelle Encarnacion, RDC, Christopher Loiselle, BS, Susan M. O'Brien, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 823.
https://doi.org/10.1182/blood-2019-125136
Published: 2019
Journal Articles

Increased Mortality and Bleeding in a Large Cohort of Patients on Heparin Anticoagulation Therapy with Discordant Anti-Factor Xa Activity and Activated Partial Thromboplastin Time (PTT); Implications for Clinical Management

Free
Saurabh Gombar, MD PhD, Derek Boothroyd, PhD, Anandi Krishnan, PhD, Husham Sharifi, MD, Joe Hsu, MD, James Zehnder, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 712.
https://doi.org/10.1182/blood-2019-132112
Published: 2019
Journal Articles

Final Clinical Results of a Phase II Study of High Dose Cytarabine Followed By Pembrolizumab in Relapsed/Refractory AML

Free
Joshua F Zeidner, MD, Benjamin G. Vincent, MD, Sonia Esparza, MD, Anastasia Ivanova, PhD, Dominic T. Moore, MPH, MS, Matthew C Foster, MD, Catherine C. Coombs, MD, Katarzyna Jamieson, MD, Hendrik W. Van Deventer, MD, Laura Blanchard, William Churchwell, Cassiopeia Frank, Sean Gallagher, Melissa Matson, AGPCNP-BC, Ashley Reed, Nancy Vogler, Jonathan Webster, MD, Gabrielle T. Prince, MD, Amy E. DeZern, MD, B. Douglas Smith, MD, Mark J. Levis, MD, Leo Luznik, MD, Jonathan S Serody, MD, Ivana Gojo, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 831.
https://doi.org/10.1182/blood-2019-126065
Published: 2019
Journal Articles

Characterization of the Severe Phenotype of Pyruvate Kinase Deficiency

Free
Hanny Al-Samkari, MD, Eduard J. van Beers, MD PhD, D Holmes Morton, MD, Wilma Barcellini, MD, Stefan W. Eber, MD, Bertil Glader, MD PhD, Hassan M. Yaish, MD, Satheesh Chonat, MD, Kevin H. M. Kuo, MDMSc,FRCPC, Nina Kollmar, MD, Jenny M. Despotovic, DO, MS, Dagmar Pospisilova, Prof MD PhD, Christine M. Knoll, MD, Janet L. Kwiatkowski, MD MSCE, Yves D. Pastore, MD, Alexis A. Thompson, MD MPH, Marcin W. Wlodarski, MD PhD, Yaddanapudi Ravindranath, MBBS, Jennifer A. Rothman, MD, Heng Wang, MD PhD, Suzanne Holzhauer, MD MSc, Vicky R. Breakey, BSc,MDFRCPC, Madeleine M. Verhovsek, MD FRCPC, Joachim B. Kunz, MD, Sujit Sheth, MD, Mukta Sharma, MD MPH, Melissa J. Rose, DO, Heather Bradeen, Melissa A. McNaull, MD, Kathryn Addonizio, BS, Hasan Al-Sayegh, Wendy B. London, PhD, Rachael F. Grace, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 949.
https://doi.org/10.1182/blood-2019-125352
Published: 2019
Journal Articles

A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+ B-Acute Lymphoblastic Leukemia (B-ALL): Results from Children's Oncology Group Protocol AALL1621

Free
Maureen M O'Brien, MD, Lingyun Ji, PhD, Nirali N. Shah, MD, Susan R. Rheingold, MD, Deepa Bhojwani, MD, Joanna S. Yi, MD, Constance M. Yuan, MD PhD, Andrew C Harris, MD, Patrick A. Brown, MD, Michael J. Borowitz, MD PhD, Olga Militano, PharmD, Meenakshi Devidas, PhD, Elizabeth A. Raetz, MD, Lia Gore, MD, Mignon L. Loh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 741.
https://doi.org/10.1182/blood-2019-128977
Published: 2019
Journal Articles

Resolution of Sickle Cell Disease Manifestations in Patients Treated with Lentiglobin Gene Therapy: Updated Results from the Phase 1/2 Hgb-206 Group C Study

Free
Julie Kanter, MD, John F. Tisdale, MD, Markus Y. Mapara, MD PhD, Janet L. Kwiatkowski, MD MSCE, Lakshmanan Krishnamurti, MD, Manfred Schmidt, PhD, Alexandra L. Miller, Francis J. Pierciey, Jr., Wenmei Huang, PhD MS, Jean-Antoine Ribeil, MD PhD, Alexis A. Thompson, MD MPH, Mark C. Walters, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 990.
https://doi.org/10.1182/blood-2019-128894
Published: 2019
Journal Articles

Sequential CD19- and Bcma-Specific Chimeric Antigen Receptor T Cell Treatment for RRMM: Report from a Single Center Study

Free
Lingzhi Yan, Zhi Yan, Jingjing Shang, Xiaolan Shi, Song Jin, Liqing Kang, Su Qu, Jin Zhou, Huizhu Kang, Ruju Wang, Ying Yao, Jing Wang, Weiqin Yao, Guanghua Chen, Lei Yu, Depei Wu, MD PhD, Fu Cheng Cheng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 578.
https://doi.org/10.1182/blood-2019-129740
Published: 2019