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Journal Articles

An Adaptive Design Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients with Non-Primary Hemophagocytic Lymphohistiocytosis

Veronica Asnaghi, MD, Maria Ballabio, MD, Philippe Jacqmin, Kathy de Graaf, Cristina De Min, MD

Blood (2019) 134 (Supplement_1): 2333.

https://doi.org/10.1182/blood-2019-123995

Published: 2019

Journal Articles

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

Blood (2018) 131 (5): 533–545.

https://doi.org/10.1182/blood-2017-10-812859

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Outcome of Children with Primary Immune-Deficiencies (PIDs) Enrolled in a Phase I-II Trial Based on the Infusion of BPX-501 Donor T Cells Genetically Modified with a Novel Suicide Gene (inducible Caspase 9, iC9) after T-Cell Depleted HLA-Haploidentical Allogeneic Stem Cell Transplantation (haplo-HSCT)

Neena Kapoor, MD, Alice Bertaina, MD PhD, Pietro Merli, MD, Swati Naik, MD, Waseem Qasim, MBBS PhD, Mary Slatter, MD, Reem Elfeky, MD, Barbarella Lucarelli, MD, Monika Smogorzewska, PhD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Annemarie Moseley, MD PhD, Franco Locatelli, MD

Blood (2016) 128 (22): 72.

https://doi.org/10.1182/blood.V128.22.72.72

Published: 2016

Journal Articles

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype

Blood (2016) 127 (25): 3154–3164.

https://doi.org/10.1182/blood-2015-11-679902

Published: 2016

Includes: Supplemental data

Journal Articles

Impairment of IL-17 Immunity to Candida and IFN-g Immunity to Mycobacterium in Humans with Bi-Allelic Rorc mutations

Satoshi Okada, MD PhD, Janet Markle, PhD, Masao Kobayashi, MD PhD, Jacinta Bustamante, MD PhD, Jean-Laurent Casanova, MD PhD

Blood (2015) 126 (23): 205.

https://doi.org/10.1182/blood.V126.23.205.205

Published: 2015

Journal Articles

MSMD Patients with IFN-g-STAT1 Signaling Defect Present Enhanced Osteoclastogenesis and Bone Resorption

Shiho Nishimura, MD, Miyuki Tsumura, PhD, Osamu Hirata, MD PhD, Reiko Kagawa, MD, Yoko Mizoguchi, MD PhD, Satoshi Okada, MD PhD, Masao Kobayashi, MD PhD

Blood (2015) 126 (23): 3591.

https://doi.org/10.1182/blood.V126.23.3591.3591

Published: 2015

Journal Articles

Natural Toll-like Receptor Agonists for in Situ Vaccination Lymphoma Immunotherapy

Paul Peng, PhD, Joshua Brody, MD, Linda Hammerich, PhD

Blood (2015) 126 (23): 4002.

https://doi.org/10.1182/blood.V126.23.4002.4002

Published: 2015

Journal Articles

An Optimized, Ex Vivo Log-Scale Expansion of UCB-Derived Myeloid Dcs, Towards Efficient Cancer Immunotherapy

Eleni Gounari, Anastasia Papadopoulou, PhD, Minas Yiangou, Prof, Angeliki E Xagorari, PhD, Achilles Anagnostopoulos, MD, Evangelia Yannaki, MD, Panayotis Kaloyannidis, MD

Blood (2014) 124 (21): 2441.

https://doi.org/10.1182/blood.V124.21.2441.2441

Published: 2014

Journal Articles

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4 + T cells

Solenne Vigne, Gaby Palmer, Praxedis Martin, Céline Lamacchia, Deborah Strebel, Emiliana Rodriguez, Maria L. Olleros, Dominique Vesin, Irene Garcia, Francesca Ronchi, Federica Sallusto, John E. Sims, Cem Gabay

Blood (2012) 120 (17): 3478–3487.

https://doi.org/10.1182/blood-2012-06-439026

Published: 2012

Includes: Supplemental data

Journal Articles

Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation

Blood (2011) 118 (21): 2045.

https://doi.org/10.1182/blood.V118.21.2045.2045

Published: 2011

Journal Articles

A Novel Mutation K673R In STAT1 Impaired the STAT1 Signal Transduction In a dominant– Negative Manner Identified In a Japanese Boy with MSMD

Yoko Mizoguchi, MD, Miyuki Tsumura, B.Sc., Satoshi Okada, MD, Hidemasa Sakai, MD, Ryuta Nishikomori, MD, Shin'ichiro Yasunaga, MD, Motoaki Ohtsubo, PhD, Takuji Murata, MD, Hideto Obata, MD, Takahiro Yasumi, MD, Toshio Heike, MD, Tatsutoshi Nakahata, MD, Yoshihiro Takihara, MD, Masao Kobayashi, MD

Blood (2010) 116 (21): 1734.

https://doi.org/10.1182/blood.V116.21.1734.1734

Published: 2010

Journal Articles

TLR2-dependent eosinophil interactions with mycobacteria: role of α-defensins

Virginie Driss, Fanny Legrand, Emmanuel Hermann, Sylvie Loiseau, Yann Guerardel, Laurent Kremer, Estelle Adam, Gaëtane Woerly, David Dombrowicz, Monique Capron

Blood (2009) 113 (14): 3235–3244.

https://doi.org/10.1182/blood-2008-07-166595

Published: 2009

Includes: Supplemental data

Journal Articles

Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo

Sanchita Bhatnagar, Kazuhiko Shinagawa, Francis J. Castellino, Jeffrey S. Schorey

Blood (2007) 110 (9): 3234–3244.

https://doi.org/10.1182/blood-2007-03-079152

Published: 2007

Journal Articles

A Novel Mutation 774del4 in IFNGR1 , Which Produces Truncated Form of Interferon γ Receptor 1, Causes a Dominant-Negative Effect on Interferon γ Signal Transduction.

Satoshi Okada, MD, Nobutsune Ishikawa, M.D., Kenichirou Shirao, M.D., Hiroshi Kawaguchi, M.D., Miyuki Tsumura, Ph.D., Yoshinori Ohno, Ph.D., Shin’ichiro Yasunaga, Ph.D., Motoaki Ohtsubo, Ph.D., Yoshihiro Takihara, Ph.D., Masao Kobayashi, M.D.

Blood (2006) 108 (11): 1246.

https://doi.org/10.1182/blood.V108.11.1246.1246

Published: 2006

Journal Articles

The β-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria

Mahesh Yadav, Jeffrey S. Schorey

Blood (2006) 108 (9): 3168–3175.

https://doi.org/10.1182/blood-2006-05-024406

Published: 2006

Journal Articles

Multicolor Fluorescence In Situ Hybridization (M-FISH) in Highly Aggressive B-Cell Lymphomas with 8q24/MYC Involvement Revealed the Heterogeneity of 13q Abnormalities with Unexpected Partial Gains.

Violaine Havelange, Geneviève Ameye, Evelyne Callet-Bauchu, Nicole Dastugue, Carole Barin, Dominique Penther, Lucienne Michaux, Anne Hagemeijer, Miikka Vikkula, Hélène Antoine-Poirel

Blood (2006) 108 (11): 2068.

https://doi.org/10.1182/blood.V108.11.2068.2068

Published: 2006

Journal Articles

Neutrophil stimulation with Mycobacterium bovis bacillus Calmette-Guérin (BCG) results in the release of functional soluble TRAIL/Apo-2L

Troy J. Kemp, Aaron T. Ludwig, James K. Earel, Jill M. Moore, Rebecca L. VanOosten, Bonita Moses, Kevin Leidal, William M. Nauseef, Thomas S. Griffith

Blood (2005) 106 (10): 3474–3482.

https://doi.org/10.1182/blood-2005-03-1327

Published: 2005

Journal Articles

Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes

Valérie Abadie, Edgar Badell, Patrice Douillard, Danielle Ensergueix, Pieter J. M. Leenen, Myriam Tanguy, Laurence Fiette, Sem Saeland, Brigitte Gicquel, Nathalie Winter

Blood (2005) 106 (5): 1843–1850.

https://doi.org/10.1182/blood-2005-03-1281

Published: 2005

Includes: Supplemental data

Journal Articles

Genetic control of myeloproliferation in BXH-2 mice

Karine Turcotte, Susan Gauthier, Loukia-Maria Mitsos, Chaim Shustik, Neal G. Copeland, Nancy A. Jenkins, Jean-Christophe Fournet, Paul Jolicoeur, Philippe Gros

Blood (2004) 103 (6): 2343–2350.

https://doi.org/10.1182/blood-2003-06-1852

Published: 2004

Journal Articles

Naturally occurring anti–IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans

Conny Höflich, Robert Sabat, Simone Rosseau, Bettina Temmesfeld, Hortense Slevogt, Wolf-Dietrich Döcke, Gerald Grütz, Christian Meisel, Elke Halle, Ulf B. Göbel, Hans-Dieter Volk, Norbert Suttorp

Blood (2004) 103 (2): 673–675.

https://doi.org/10.1182/blood-2003-04-1065

Published: 2004

NARROW

An Adaptive Design Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients with Non-Primary Hemophagocytic Lymphohistiocytosis

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype

Impairment of IL-17 Immunity to Candida and IFN-g Immunity to Mycobacterium in Humans with Bi-Allelic Rorc mutations

MSMD Patients with IFN-g-STAT1 Signaling Defect Present Enhanced Osteoclastogenesis and Bone Resorption

Natural Toll-like Receptor Agonists for in Situ Vaccination Lymphoma Immunotherapy

An Optimized, Ex Vivo Log-Scale Expansion of UCB-Derived Myeloid Dcs, Towards Efficient Cancer Immunotherapy

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4 + T cells

Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation

A Novel Mutation K673R In STAT1 Impaired the STAT1 Signal Transduction In a dominant– Negative Manner Identified In a Japanese Boy with MSMD

TLR2-dependent eosinophil interactions with mycobacteria: role of α-defensins

Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo

A Novel Mutation 774del4 in IFNGR1 , Which Produces Truncated Form of Interferon γ Receptor 1, Causes a Dominant-Negative Effect on Interferon γ Signal Transduction.

The β-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria

Multicolor Fluorescence In Situ Hybridization (M-FISH) in Highly Aggressive B-Cell Lymphomas with 8q24/MYC Involvement Revealed the Heterogeneity of 13q Abnormalities with Unexpected Partial Gains.

Neutrophil stimulation with Mycobacterium bovis bacillus Calmette-Guérin (BCG) results in the release of functional soluble TRAIL/Apo-2L

Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes

Genetic control of myeloproliferation in BXH-2 mice

Naturally occurring anti–IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans

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American Society of Hematology

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American Society of Hematology

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