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Journal Articles

Discovery of DWP213388, a Potent ITK and BTK Selective Dual Inhibitor with Excellent Efficacy and Safety, for Treating Gvhd

Deokki Eom, BS, Jae Hun Jung, Eun Kyung KIM, PhD, Wolyoung Kim, Qingri Li, Jaehyun Jung, Sohee Im, Yong Dae Shin, Hyaejung Hyun, Joon Seok Park

Blood (2019) 134 (Supplement_1): 4426.

https://doi.org/10.1182/blood-2019-126839

Published: 2019

Journal Articles

Restoring Innate and Adaptive Immune Repertoire in Multiple Myeloma for Therapeutic Application

Rafael Alonso Fernández, MD, Laetitia Pierre-Louis, Rao Prabhala, Yan Xu, MD, Joaquin Martinez-Lopez, MD PhD, Takahiro Miyazaki, Mehmet Kemal Samur, PhD, Loui Madakamutil, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4398.

https://doi.org/10.1182/blood-2019-128767

Published: 2019

Journal Articles

Low Numbers of CD27 - IgD - 'Double Negative' Senescent B-Cells Early after Reduced Intensity T Cell Depleted Haematopoietic Stem Cell Transplantation Are Predictive of Subsequent Chronic GvHD

Francesca Kinsella, PhD MRCP, FRCPath, Harriet Protheroe, MBChB BSc, Hayden Pearce, BSc. (Hons.), PhD, Charlotte F Inman, BVSc, PhD, Suzy A Eldershaw, BSc. (Hons.), PhD, Joanne Croudace, PhD, Ben E Abbotts, BSc. (Hons.), MSc., Jianmin Zuo, PhD, Ram K Malladi, FRCPath, Charles Craddock, FRCP, FRCPath, Paul Moss, MBBS, PhD FRCP

Blood (2019) 134 (Supplement_1): 4529.

https://doi.org/10.1182/blood-2019-131130

Published: 2019

Journal Articles

Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd

Jonathan C Poe, PhD, Dadong Zhang, PhD, Jichun Xie, PhD, Rachel A. DiCioccio, BS, Xiaodi Qin, MS, Jiyuan Fang, MS, Vincent T. Ho, MD, Jeremy J. Rose, MS, Steven Z. Pavletic, MD MS, Frances T. Hakim, PhD, Wei Jia, MD PhD, Amy N. Suthers, PhD, Mitchell E. Horwitz, MD, David A. Rizzieri, MD, William C. McManigle, MD, Nelson J. Chao, MD, Kouros Owzar, PhD, Stefanie Sarantopoulos, MD PhD

Blood (2019) 134 (Supplement_1): 874.

https://doi.org/10.1182/blood-2019-130928

Published: 2019

Journal Articles

CLL B Cells Develop Resistance to Ibrutinib By Reinvigorating the IL-4R - IL-4 Axis Blocked By Bruton's Tyrosine Kinase Inhibitors Including Acalabrutinib and Zanubrutinib

Shih-Shih Chen, PhD, Constantine S. Tam, MBBS (Hons), MD, Alan G. Ramsay, BSc,MSc,PhD, Priyadarshini Ravichandran, Natalia C. Couto-Francisco, Michael Ibrahim, Gerardo Ferrer, PhD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, He Zhou, Jacqueline C Barrientos, MD, Kanti R Rai, MD, Nicholas Chiorazzi, MD

Blood (2019) 134 (Supplement_1): 477.

https://doi.org/10.1182/blood-2019-127255

Published: 2019

Journal Articles

Unswitched Memory B Cell Deficiency Is Associated with Acute Chest Syndrome and Stroke in Sickle Cell Disease

Sameera Bhamidipati, MA, Venee N. Tubman, MD, Norma Estrada, Charles Minard, PhD

Blood (2019) 134 (Supplement_1): 1010.

https://doi.org/10.1182/blood-2019-128575

Published: 2019

Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

CD Maps - Dynamic Profiling of CD1 to CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets

Karel Fišer, PhD, Tomas Kalina, MD PhD, Martin Perez-Andres, Daniela Kužílková, PhD, Pablo Engel, Marta Cuenca, PhD, Elena Blanco Álvarez, Sophinus J.W. Bartol, Menno C. van Zelm

Blood (2019) 134 (Supplement_1): 4878.

https://doi.org/10.1182/blood-2019-128123

Published: 2019

Journal Articles

Vaccination with Live Attenuated Virus Vaccines in Four Pediatric Patients with CML While on Imatinib Treatment

Claudia Bettoni Da Cunha-Riehm, MD, Verena Hildebrand, MD, Michaela Nathrath, MD PhD, Markus Metzler, MD PhD, Meinolf Suttorp, MD PhD

Blood (2019) 134 (Supplement_1): 5903.

https://doi.org/10.1182/blood-2019-122219

Published: 2019

Journal Articles

Dynamics of the Bone Marrow Microenvironment during Leukemic Progression Revealed By Codex Hyper-Parameter Tissue Imaging

Christian Schuerch, MD PhD, Graham L. Barlow, BA, Salil S. Bhate, MMath, Nikolay Samusik, PhD, Garry P. Nolan, PhD, Yury Goltsev, PhD

Blood (2018) 132 (Supplement 1): 935.

https://doi.org/10.1182/blood-2018-99-111708

Published: 2018

Journal Articles

The Expression of BTK/p-BTK Is Different between CD5 + and CD5 - B Lymphocyte from Autoimmune Hemolytic Anemia/Evans Syndromes

Limin Xing, Yingying Qu, Ningning Duan, Zonghong Shao, MD

Blood (2018) 132 (Supplement 1): 4886.

https://doi.org/10.1182/blood-2018-99-114339

Published: 2018

Journal Articles

Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution

Ronan Chaligne, PhD, Federico Gaiti, PhD, Franco Izzo, PhD, Steven Kothen-Hill, MS, Hongcang Gu, Kevin Huang, BS, Davide Risso, PhD, Rafael Schulman, BS, Ryan M Brand, Stanley C Lee, PhD, Asaf Poran, Kye-Tae Kim, PhD, Alessandro Pastore, Alicia Alonso, Andreas Gnirke, Catherine J. Wu, MD, Omar I Abdel-Wahab, MD, Alexander Meissner, PhD, Dan A. Landau, MD PhD

Blood (2018) 132 (Supplement 1): 1312.

https://doi.org/10.1182/blood-2018-99-115596

Published: 2018

Journal Articles

Resistance of Natural Killer and T Cells to Venetoclax Allows for Combination Treatment with Cancer Immunotherapy Agents

Elisabeth A Lasater, PhD, An D Do, Luciana Burton, Yijin Li, Erin Williams, Jason Oeh, Luciana Molinero, Elicia Penuel, Deepak Sampath, Monique Dail, Marcia Belvin, Teiko Sumiyoshi, Elizabeth A Punnoose, Jeffrey Venstrom, Aparna Raval

Blood (2018) 132 (Supplement 1): 1118.

https://doi.org/10.1182/blood-2018-99-116405

Published: 2018

Journal Articles

Circulating B Cell Subsets from Untreated Diffuse Large B Cell Lymphoma (DLBCL) Patients Resemble Those of Patients with Autoimmune Disease

Jean L. Koff, MD, Kevin S. Cashman, PhD, Vivien Warren, Kira Smith, PhD, Christopher R Flowers, MD MS, Ignacio Sanz, MD

Blood (2018) 132 (Supplement 1): 4221.

https://doi.org/10.1182/blood-2018-99-119031

Published: 2018

Journal Articles

Deep Immunoprofiling of the Bone Marrow Microenvironmental Changes Underlying the Multistep Progression of Multiple Myeloma

Mary H Young, PhD, Sam A Danziger, Alison Fitch, Frank Schmitz, MD PhD, Jake Gockley, PhD, Mark McConnell, PhD, David Reiss, PhD, Wilbert B. Copeland, PhD, Sarah K Johnson, PhD, Katie Newhall, PhD, Robert Hershberg, MD PhD, Teri Foy, PhD, Alexander Ratushny, PhD, Brian A Walker, PhD, Andrew Dervan, Gareth Morgan, MD

Blood (2018) 132 (Supplement 1): 243.

https://doi.org/10.1182/blood-2018-99-113042

Published: 2018

Journal Articles

Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individuals

Felicia A. Tucci, Simo Kitanovski, Patricia Johansson, Ludger Klein-Hitpass, Alisan Kahraman, Jan Dürig, Daniel Hoffmann, Ralf Küppers

Blood (2018) 131 (5): 546–557.

https://doi.org/10.1182/blood-2017-09-805762

Published: 2018

Includes: Supplemental data

Journal Articles

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

Rao Prabhala, PhD, Shree Acharya, MS, Megan Stekla, BS, Srikanth Talluri, PhD, Raphael Szalat, MD, Puru Nanjappa, Michael A Lopez, BS, Kenneth Wen, BS, Chaitanya Yenumula, MD, Alexander Heubeck, BS, Yu-Tzu Tai, PhD, Ansh Mehta, MBBS, Mariateresa Fulciniti, PhD, Suzan Lazo-Kallanian, BS, John Daley, PhD, Paul G Richardson, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 3049.

https://doi.org/10.1182/blood.V130.Suppl_1.3049.3049

Published: 2017

Journal Articles

IRF5 Loss Impairs TLR9/BCR-Induced B Cell Activation, Proliferation and Plasmablast Differentiation through Erk1-Myc Signaling

Betsy Barnes, DPhil, Saurav De, Aaron Winkler, Baohong Zhang

Blood (2017) 130 (Supplement 1): 3580.

https://doi.org/10.1182/blood.V130.Suppl_1.3580.3580

Published: 2017

Journal Articles

B-Cell Differentiation Dependent Classification of Diffuse Large B-Cell Lymphoma By the Nanostring Technology

Thomas Yssing Michaelsen, BS, Rasmus Froberg Brøndum, Senior Bioinformatician, Julia Richter, PhD, Wolfram Klapper, MD, Mads Albertsen, Associate Professor, Hans Erik Johnsen, MD Professor, Karen Dybkær, Professor, Tarec Christoffer El-Galaly, MD PhD, Martin Bøgsted, Professor

Blood (2017) 130 (Supplement 1): 3995.

https://doi.org/10.1182/blood.V130.Suppl_1.3995.3995

Published: 2017

Journal Articles

Impact of Pre-Emptive Rituximab Treatment for Epstein-Barr Virus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation: A Longitudinal Study of 110 Patients

Nicolas Stocker, MD, Myriam Labopin, MD PhD, Inès Boussen, MD, Baptiste Lamarthée, PhD, Florent Malard, MDPhD, Agnès Bonnin, Vincent Marechal, PhD, Corinne Amiel, MD, Frédérique Quignon, PhD, Joël Gozlan, MD, Giorgia Battipaglia, MD, Remy Duléry, MD, Federica Giannotti, MD, Annalisa Ruggeri, MD, Béatrice Gaugler, PhD, Mohamad Mohty, MD PhD, Eolia Brissot, MDPhD

Blood (2017) 130 (Supplement 1): 4519.

https://doi.org/10.1182/blood.V130.Suppl_1.4519.4519

Published: 2017

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Discovery of DWP213388, a Potent ITK and BTK Selective Dual Inhibitor with Excellent Efficacy and Safety, for Treating Gvhd

Restoring Innate and Adaptive Immune Repertoire in Multiple Myeloma for Therapeutic Application

Low Numbers of CD27 - IgD - 'Double Negative' Senescent B-Cells Early after Reduced Intensity T Cell Depleted Haematopoietic Stem Cell Transplantation Are Predictive of Subsequent Chronic GvHD

Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd

CLL B Cells Develop Resistance to Ibrutinib By Reinvigorating the IL-4R - IL-4 Axis Blocked By Bruton's Tyrosine Kinase Inhibitors Including Acalabrutinib and Zanubrutinib

Unswitched Memory B Cell Deficiency Is Associated with Acute Chest Syndrome and Stroke in Sickle Cell Disease

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

CD Maps - Dynamic Profiling of CD1 to CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets

Vaccination with Live Attenuated Virus Vaccines in Four Pediatric Patients with CML While on Imatinib Treatment

Dynamics of the Bone Marrow Microenvironment during Leukemic Progression Revealed By Codex Hyper-Parameter Tissue Imaging

The Expression of BTK/p-BTK Is Different between CD5 + and CD5 - B Lymphocyte from Autoimmune Hemolytic Anemia/Evans Syndromes

Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution

Resistance of Natural Killer and T Cells to Venetoclax Allows for Combination Treatment with Cancer Immunotherapy Agents

Circulating B Cell Subsets from Untreated Diffuse Large B Cell Lymphoma (DLBCL) Patients Resemble Those of Patients with Autoimmune Disease

Deep Immunoprofiling of the Bone Marrow Microenvironmental Changes Underlying the Multistep Progression of Multiple Myeloma

Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individuals

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

IRF5 Loss Impairs TLR9/BCR-Induced B Cell Activation, Proliferation and Plasmablast Differentiation through Erk1-Myc Signaling

B-Cell Differentiation Dependent Classification of Diffuse Large B-Cell Lymphoma By the Nanostring Technology

Impact of Pre-Emptive Rituximab Treatment for Epstein-Barr Virus Reactivation after Allogeneic Hematopoietic Stem Cell Transplantation: A Longitudinal Study of 110 Patients

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