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Characterizing C5 Inhibition with the SMART-Ig Anti-hC5 Antibody Crovalimab in PNH Patients Using Free Available Paratopes

Alexandre Sostelly, M.Eng., PhD, Antoine Soubret, Christoph Bucher, MD, Simon Buatois, Jean-Eric Charoin, Gregor Jordan, Barbara Klughammer, PhD, Andreas Dieckmann, Taku Fukuzawa, PhD, Keisuke Gotanda, Kenji Shinomiya, Sung-Soo Yoon, MD PhD, Jens P. Panse, Junichi Nishimura, MD PhD, Alexander Röth, MD PhD, Zsolt Nagy, MD PhD, Régis Peffault de Latour, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1227.
https://doi.org/10.1182/blood-2019-126911
Published: 2019
Journal Articles

Redirecting T-Cells Against AML in a Multidimensional Targeting Space Using T-Cell Engaging Antibody Circuits (TEAC)

Eleanor Minogue, BSc, David Millar, PhD, Yan Chuan, PhD, Songfa Zhang, MD PhD, Korneel Grauwet, PhD, Mei Guo, Adam Langenbucher, Cyril H Benes, James Heather, PhD, Jeremy Minshull, PhD, Michael S. Lawrence, PhD, Rupa Narayan, David M. Langenau, PhD, Timothy A. Graubert, MD, Mark Cobbold
Journal: Blood
Blood (2019) 134 (Supplement_1): 2653.
https://doi.org/10.1182/blood-2019-127634
Published: 2019
Journal Articles

Ex Vivo Assessment of Tnb-383B, a Bcma-Bispecific Antibody, Against Primary Tumor and Endogenous T Cells from Relapsing Multiple Myeloma Patients

David M. Foureau, PhD, Manisha Bhutani, MD, Myra Robinson, MS, Fei Guo, PhD, Duy Pham, Shelley Force Aldred, Ben Buelow, MD PhD, Katherine Rigby, Elise Tjaden, Marina Leonidas, Shebli Atrash, Ami P Ndiaye, NP, James Symanowski, PhD, Peter M. Voorhees, MD, Saad Z. Usmani, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1940.
https://doi.org/10.1182/blood-2018-99-118881
Published: 2018
Journal Articles

CD33 DE2 Transcript Variant Encoded By Splicing Polymorphism Is Devoid of Antibody Binding Site and Lacks Response to CD33 Directed Antibody Drug Conjugates

Katherine Tarlock, MD, Jatinder Lamba, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2661.
https://doi.org/10.1182/blood.V130.Suppl_1.2661.2661
Published: 2017
Journal Articles

ZW38, a Novel Azymetric Bispecific CD19-Directed CD3 T Cell Engager Antibody Drug Conjugate with Controlled T Cell Activation and Improved B Cell Cytotoxicity

Gordon Ng, PhD MSc, BSc, Thomas Spreter, PhD, Rupert Davies, PhD, Grant Wickman, PhD
Journal: Blood
Blood (2016) 128 (22): 1841.
https://doi.org/10.1182/blood.V128.22.1841.1841
Published: 2016
Journal Articles

Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin alphaIIbbeta3

Jianghai Zhu, PhD, Jieqing Zhu, PhD, Daniel W. Bougie, PhD, Richard H. Aster, MD, Timothy A. Springer, PhD
Journal: Blood
Blood (2015) 126 (23): 1063.
https://doi.org/10.1182/blood.V126.23.1063.1063
Published: 2015
Journal Articles

Chystallographic Evidence of Autologous Recognition By a Clonotypic B Cell Receptor in Chronic Lymphocytic Leukemia

Maria Gounari, PhD, Claudia Minici, PhD, Marcus Dühren-von Minden, Schneider Dunja, Alkhatib Alabbas, Übelhart Rudolf, Andreas Agathangelidis, Stavroula Ntoufa, Nicholas Chiorazzi, MD, Hassan Jumaa, Kostas Stamatopoulos, Massimo Degano, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4129.
https://doi.org/10.1182/blood.V126.23.4129.4129
Published: 2015
Journal Articles

Deuterium-Hydrogen Exchange Coupled With Mass Spectrometry Revealed A Novel Autoantibody Binding Epitope and Substrate Recognition Site In ADAMTS13 Protease,

Veronica C. Casina, Ph.D, Wenbing Hu, Ph.D., Hayley A. Hanby, B.S., Don L. Siegel, M.D., Ph.D, Leland Mayne, Ph.D., S. Walter Englander, Ph.D., X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 455.
https://doi.org/10.1182/blood.V122.21.455.455
Published: 2013
Journal Articles

Restricted Pairing of Immunoglobulin Heavy and Light Chains Expressed by Chronic Lymphocytic Leukemia B Cells Is Predicated on the Heavy Chain CDR3.

George F. Widhopf, PhD, Craig J. Goldberg, BS, Traci L. Toy, BS, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2094.
https://doi.org/10.1182/blood.V106.11.2094.2094
Published: 2005
Journal Articles

Differential Expression of CD180 and sIgM by B Chronic Lymphocytic Leukaemia Cells (B-CLL) Using Mutated and Unmutated IgVh Genes.

Nino Porakishvili, PhD, Nino Kulikova, PhD, Maria Manoussaka, PhD, Andrew P. Jewell, PhD, Pierre Y. Youinou, PhD, S. Nedelec, PhD, Kwee Yong, PhD, Amit Nathwani, MD, B. Heelan, PhD, Terry Hamblin, MD, P. Wallace, PhD, P. Ely, PhD, Ed Clarke, PhD, Peter M. Lydyard, PhD
Journal: Blood
Blood (2004) 104 (11): 2807.
https://doi.org/10.1182/blood.V104.11.2807.2807
Published: 2004
Journal Articles

Variability of PECAM-1 Expression on Blood Cells.

Melanie S. Berken, Ph.D., Debra K. Newman, Ph.D., Peter J. Newman, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3885.
https://doi.org/10.1182/blood.V104.11.3885.3885
Published: 2004
Journal Articles

Inhibition of malarial parasite invasion by monoclonal antibodies against glycophorin A correlates with reduction in red cell membrane deformability

G Pasvol, JA Chasis, N Mohandas, DJ Anstee, MJ Tanner, AH Merry
Journal: Blood
Blood (1989) 74 (5): 1836–1843.
https://doi.org/10.1182/blood.V74.5.1836.1836
Published: 1989