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Journal Articles

Integrated Multi-Level Omics to Characterize Bortezomib Resistance in Multiple Myeloma

Blood (2019) 134 (Supplement_1): 5534.

https://doi.org/10.1182/blood-2019-132001

Published: 2019

Journal Articles

A CK1δ/CK1ε Regulated Metabolic Circuit Is a Therapeutic Vulnerability for Multiple Myeloma

Karen L Burger, PhD, Mark B. Meads, PhD, Anders Berglund, Paula S. Oliveira, Allison Distler, Praneeth Reddy Sudalagunta, PhD, Timothy Jacobson, Jamie Teer, PhD, Eric A. Welsh, PhD, Hongyue Dai, PhD, John M. Koomen, PhD, Alugubelli Raghunandan Reddy, Gabriel De Avila, Alexandre Tungesvik, MD, William Roush, PhD, Ariosto Siqueira Silva, PhD, Kenneth H. Shain, MD PhD, John Cleveland, PhD

Blood (2019) 134 (Supplement_1): 5537.

https://doi.org/10.1182/blood-2019-130830

Published: 2019

Journal Articles

Proteometabolomics of Melphalan Resistance in Multiple Myeloma

David C. Koomen, BS, Joy D. Guingab, PhD, Paula S. Oliveira, Bin Fang, PhD, Min Liu, PhD, Eric A. Welsh, PhD, Mark B. Meads, PhD, Tuan Nguyen, Laurel E. Meke, Steven A. Eschrich, PhD, Timothy J. Garrett, PhD, John M. Koomen, PhD, Kenneth H. Shain, MD PhD

Blood (2018) 132 (Supplement 1): 5619.

https://doi.org/10.1182/blood-2018-99-117747

Published: 2018

Journal Articles

Systems Biology Analysis Identifies Targetable Vulnerability Networks to Proteasome Inhibitors in Multiple Myeloma

Mark B. Meads, PhD, Rafael Renatino Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Paula S. Oliveira, Dario M. Magaletti, Bin Fang, PhD, Maria D Coelho Siqueira Silva, MSc, Amit Kulkarni, PhD, Hongyue Dai, PhD, William S. Dalton, PhDMD, Ion Petre, PhD, John M. Koomen, PhD, Ariosto Siqueira Silva, PhD, Kenneth H. Shain, MD PhD

Blood (2018) 132 (Supplement 1): 950.

https://doi.org/10.1182/blood-2018-99-120269

Published: 2018

Journal Articles

A CK1δ/CK1ε-to-β-Catenin Circuit Is a Therapeutic Vulnerability for Primary and Drug Resistant Multiple Myeloma

Karen L Burger, PhD, Mark B. Meads, PhD, Ariosto Siqueira Silva, PhD, Paula Oliveira, Tuan Nguyen, Allison Distler, Maria Coelho Siqueira Silva, Timothy Jacobson, Jamie Teer, PhD, Hongyue Dai, PhD, William Roush, PhD, John Cleveland, PhD, Kenneth H Shain, MD PhD

Blood (2017) 130 (Supplement 1): 591.

https://doi.org/10.1182/blood.V130.Suppl_1.591.591

Published: 2017

Journal Articles

Proteomic Analysis Reveals IRAK4 As a Therapeutic Target in Chronic Lymphocytic Leukemia

Christina Wu, PhD, Ekaterina Vinogradova, PhD, Fitzgerald Lao, Emily Nan, Katie Ta, Karen Messer, PhD, Michael Choi, MD, Benjamin F. Cravatt, PhD, Dennis A. Carson, MD

Blood (2017) 130 (Supplement 1): 3838.

https://doi.org/10.1182/blood.V130.Suppl_1.3838.3838

Published: 2017

Journal Articles

Identification of Target Pathways of Acquired IMiD and Proteasome Inhibitor Resistance in Multiple Myeloma

Mark B. Meads, PhD, Paula Oliveira, Bin Fang, Praneeth Sudalagunta, PhD, Maria D Coelho Siqueira Silva, MSc, Tuan Nguyen, Allison Distler, Salah-Eddin Komrokji, Aunshka Collins, Hongyue Dai, PhD, John M. Koomen, Ariosto Siqueira Silva, PhD, Kenneth H Shain, MD PhD

Blood (2017) 130 (Supplement 1): 4411.

https://doi.org/10.1182/blood.V130.Suppl_1.4411.4411

Published: 2017

Journal Articles

A New Multi-Factor Risk Score System Depending on Gene Mutation and Overexpression for Predicting the Outcome in AML1-ETO-Positive Acute Myeloid Leukemia

Guo-Pan Yu, MD, Changxin Yin, Fuqun Wu, Dan Xu, Zhongxin Zheng, Ling Jiang, PhD MD, Fang Chen, Xuejie Jiang, MD, Qifa Liu, Fanyi Meng

Blood (2017) 130 (Supplement 1): 5088.

https://doi.org/10.1182/blood.V130.Suppl_1.5088.5088

Published: 2017

Journal Articles

MiR-144 Targets APP to Regulate AML1/ETO+ Leukemia Cell Migration Via p-ERK/c-Myc/MMP-2 Pathway

Fanyi Meng, Ling Jiang, PhD MD, Wei Meng, PhD, Guo-Pan Yu, MD, Yin Changxin, Zhixiang Wang, PhD, Xuejie Jiang, MD, Qifa Liu

Blood (2017) 130 (Supplement 1): 5093.

https://doi.org/10.1182/blood.V130.Suppl_1.5093.5093

Published: 2017

Journal Articles

Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice

Ilaria Canobbio, Caterina Visconte, Stefania Momi, Gianni Francesco Guidetti, Marta Zarà, Jessica Canino, Emanuela Falcinelli, Paolo Gresele, Mauro Torti

Blood (2017) 130 (4): 527–536.

https://doi.org/10.1182/blood-2017-01-764910

Published: 2017

Journal Articles

Identification of Target Pathways Induced By the Multiple Myeloma Tumor Microenvironment Using Activity-Based Protein Profiling and Ex Vivo Protein Kinase Inhibitor Screening

Mark B Meads, PhD, Paula Oliveira, BS, Allison Distler, B.S., Maria Silva, M.Sc, Karen Burger, PhD, Bin Fang, PhD, Aunshka Collins, BS, John L. Cleveland, PhD, John M. Koomen, PhD, Ariosto Silva, PhD, Dmitri Rebatchouk, PhD, Kenneth H. Shain, MD PhD, William R. Roush, PhD

Blood (2016) 128 (22): 3288.

https://doi.org/10.1182/blood.V128.22.3288.3288

Published: 2016

Journal Articles

Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells Towards Cytostatics

Fabian Koczian, Jan Vomacka, Binje Vick, PhD, Britta F Hettich, Uli Kazmaier, Stephan A Sieber, Irmela Jeremias, MD, Angelika M Vollmar, Simone Braig

Blood (2016) 128 (22): 2319.

https://doi.org/10.1182/blood.V128.22.2319.2319

Published: 2016

Journal Articles

APP Gene Involves in the Regulation of Cell Apoptosis in AML1-ETO-Positive Leukemia Via SCF/c-Kit Signaling Pathway

Guopan Yu, Ling Jiang, Changxin Yin, Zhixiang Wang, Hongsheng Zhou, Xuejie Jiang, Qifa Liu, MD, Fanyi Meng

Blood (2015) 126 (23): 3647.

https://doi.org/10.1182/blood.V126.23.3647.3647

Published: 2015

Journal Articles

APP Gene Is Correlated with C-KIT Mutations and Indicates Poor Disease Outcome in AML1-ETO-Positive Acute Myeloid Leukemia

Guopan Yu, MD, Ling Jiang, MDPhD, Fan Yi Meng, MD, Changxin Yin, Zhixiang Wang, MD, Hongsheng Zhou, MDPhD, Xuejie Jiang, MDPhD, Qingxiu Zhong, MD, Rui Cao, Libin Liao

Blood (2014) 124 (21): 942.

https://doi.org/10.1182/blood.V124.21.942.942

Published: 2014

Journal Articles

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

Vanessa Schneider, Lars Bullinger, MD, PhD, Lu Zhang, Markus Rojewski, Markus Wiesneth, Susanne Hofmann, Marlies Goetz, Hubert Schrezenmeier, MD, Ulla Botzenhardt, Thomas F.E. Barth, Konstanze Doehner, MD, Hartmut Doehner, MD, Jochen Greiner, MD

Blood (2013) 122 (21): 2624.

https://doi.org/10.1182/blood.V122.21.2624.2624

Published: 2013

Journal Articles

Molecular Mechanism Of Regulation Of Extramedullary Infiltration In AML1/ETO Positive Acute Myeloid Leukemia By APP/ERK/MMP-2

Guopan Yu, MD, Fan Yi Meng, MD, Ling Jiang, MD/PH.D, Changxin Yin, MD, Zhixiang Wang, MD, Hongsheng Zhou, Xuejie Jiang, MD/PH.D, Lingxiu Zhang, MD, Rui Cao, Libin Liao, MB

Blood (2013) 122 (21): 3769.

https://doi.org/10.1182/blood.V122.21.3769.3769

Published: 2013

Journal Articles

Identification of AADACL1 As a Novel Regulator of Human Platelets Via Chemoproteomics

Stephen P. Holly, PhD, Jae Won Chang, PhD, Sherry Niessen, PhD, Yacine Boulaftali, PhD, Matthew C. Smith, Ryan M. Phillips, Justin L. Black, Raymond Piatt, Weiwei Li, PhD, Andrew S. Weyrich, PhD, Wolfgang Bergmeier, PhD, Benjamin F. Cravatt, PhD, Leslie V. Parise, PhD

Blood (2012) 120 (21): 381.

https://doi.org/10.1182/blood.V120.21.381.381

Published: 2012

Journal Articles

Exon Skipping and Alternative Splicing of CPB2 mRNA in Multiple Cell Types Results in Variants of TAFI That Are Inactive and Not Secretable

Joellen H. H. Lin, M.Sc., Mathieu Garand, Ph.D., Branislava Zagorac, B.Sc., Anastassia Filipieva, B.Sc., Marlys L Koschinsky, Ph.D., Michael B Boffa, Ph.D.

Blood (2011) 118 (21): 1189.

https://doi.org/10.1182/blood.V118.21.1189.1189

Published: 2011

Journal Articles

Expression and Role of APP Gene in Acute Myeloid Leukemia.

Fanyi Meng, Wei Wang, Zoufang Huang, Ming Huang, Lixiang Liu

Blood (2009) 114 (22): 4691.

https://doi.org/10.1182/blood.V114.22.4691.4691

Published: 2009

Journal Articles

Structural and Functional Significance of Amino Acid Lysine192 (chymotrypsin numbering) in Factor XIa and Factor VIIa.

Amy E Schmidt, Sayeh Agah, Mao-fu Sun, Kaillathe Padmanabhan, Duilio Cascio, David Gailani, S. Paul Bajaj

Blood (2008) 112 (11): 2030.

https://doi.org/10.1182/blood.V112.11.2030.2030

Published: 2008

NARROW

Integrated Multi-Level Omics to Characterize Bortezomib Resistance in Multiple Myeloma

A CK1δ/CK1ε Regulated Metabolic Circuit Is a Therapeutic Vulnerability for Multiple Myeloma

Proteometabolomics of Melphalan Resistance in Multiple Myeloma

Systems Biology Analysis Identifies Targetable Vulnerability Networks to Proteasome Inhibitors in Multiple Myeloma

A CK1δ/CK1ε-to-β-Catenin Circuit Is a Therapeutic Vulnerability for Primary and Drug Resistant Multiple Myeloma

Proteomic Analysis Reveals IRAK4 As a Therapeutic Target in Chronic Lymphocytic Leukemia

Identification of Target Pathways of Acquired IMiD and Proteasome Inhibitor Resistance in Multiple Myeloma

A New Multi-Factor Risk Score System Depending on Gene Mutation and Overexpression for Predicting the Outcome in AML1-ETO-Positive Acute Myeloid Leukemia

MiR-144 Targets APP to Regulate AML1/ETO+ Leukemia Cell Migration Via p-ERK/c-Myc/MMP-2 Pathway

Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice

Identification of Target Pathways Induced By the Multiple Myeloma Tumor Microenvironment Using Activity-Based Protein Profiling and Ex Vivo Protein Kinase Inhibitor Screening

Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells Towards Cytostatics

APP Gene Involves in the Regulation of Cell Apoptosis in AML1-ETO-Positive Leukemia Via SCF/c-Kit Signaling Pathway

APP Gene Is Correlated with C-KIT Mutations and Indicates Poor Disease Outcome in AML1-ETO-Positive Acute Myeloid Leukemia

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

Molecular Mechanism Of Regulation Of Extramedullary Infiltration In AML1/ETO Positive Acute Myeloid Leukemia By APP/ERK/MMP-2

Identification of AADACL1 As a Novel Regulator of Human Platelets Via Chemoproteomics

Exon Skipping and Alternative Splicing of CPB2 mRNA in Multiple Cell Types Results in Variants of TAFI That Are Inactive and Not Secretable

Expression and Role of APP Gene in Acute Myeloid Leukemia.

Structural and Functional Significance of Amino Acid Lysine192 (chymotrypsin numbering) in Factor XIa and Factor VIIa.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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