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Journal Articles

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

Benjamin Watkins, Yvonne Suessmuth, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Muna Qayed, MD MSc, Kathryn Pellegrini, Steven Bosinger, Amelia Langston, MD, John T. Horan, MDMPH, Bruce R. Blazar, MD, Leslie Kean, MD PhD

Blood (2019) 134 (Supplement_1): 596.

https://doi.org/10.1182/blood-2019-131955

Published: 2019

Journal Articles

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Acute Leukemia in Children

Larisa Shelikhova, MD, Rimma Khismatullina, MD, Michael Maschan, MD MSc, Alexey A. Maschan, MD, Irina Kalinina, MD, Elena Kurnikova, Yakov Muzalevsky, Alexey Kazachenok, Dmitriy Pershin, Alexander Popov, MD PhD, Galina Novichkova, MD PhD, Dmitriy Balashov, MD PhD, Daria Shasheleva, MD, Svetlana Kashpor, Evgeny Gluhanyuk

Blood (2019) 134 (Supplement_1): 150.

https://doi.org/10.1182/blood-2019-129765

Published: 2019

Journal Articles

Abatacept Is Effective for Gvhd Prophylaxis after Unrelated Donor Stem Cell Transplantation (URD SCT) for Severe Sickle Cell Disease (SCD)

Alexander I. Ngwube, MD, Niketa C. Shah, MD, David Jacobsohn, MD, Edward Dela Ziga, MD, Shalini Shenoy, MD

Blood (2019) 134 (Supplement_1): 370.

https://doi.org/10.1182/blood-2019-126405

Published: 2019

Journal Articles

Elimination of Acute GvHD with Three Doses of Abatacept Prophylaxis Combined with Post-Transplant Cyclophosphamide after Myeloablative Treosulfan-Based Conditioning in the HLA Identical Sibling and Unrelated (10-12/12) Peripheral Blood Stem Cell Donor Setting: Improved Safety and Efficacy Compared to Alemtuzumab Prophylaxis

Amit Patel, MBBS,PhDFRCPath,MRCP, Jun Yong, MBChB, MRCP(UK)

Blood (2019) 134 (Supplement_1): 4540.

https://doi.org/10.1182/blood-2019-130184

Published: 2019

Journal Articles

Haploidentical Stem Cell Transplantation with TCR Alpha/Beta and CD19 Depletion in Adult Patients with Hematological Malignancies

Maria V. Dovydenko, MD PhD, Elena N. Parovichnikova, MD PhD, Larisa A. Kuzmina, MD PhD, Vera A. Vasilyeva, MD PhD, Mikhail Yu. Drokov, MD PhD, Olga M. Koroleva, MD, Ekaterina D. Mikhaltsova, MD PhD, Natalia N. Popova, MD, Zoya V. Konova, Anna A. Dmitrova, MD, Ulyana V. Maslikova, MD, Olga S. Starikova, MD, Tatiana V. Gaponova, MD PhD, Denis V. Kamelskih, MD, Michael Maschan, MDMSc, Valeriy G. Savchenko, MD PhD

Blood (2019) 134 (Supplement_1): 5648.

https://doi.org/10.1182/blood-2019-131316

Published: 2019

Journal Articles

Itolizumab As a Potential Therapeutic for the Prevention and Treatment of Graft Vs Host Disease

Cherie Tracy Ng, PhD MPH, Jeanette Ampudia, BSc, Robert J. Soiffer, MD, Jerome Ritz, MD, Stephen Connelly, PhD MBA

Blood (2019) 134 (Supplement_1): 5603.

https://doi.org/10.1182/blood-2019-122787

Published: 2019

Journal Articles

Flow Cytometry-Based Pre-Transplant Minimal Residual Disease Detection Strongly Impacts on the Outcome of Haploidentical Transplantation with Αβ T Cell Depletion in Pediatric Acute Lymphoblastic Leukemia

Blood (2019) 134 (Supplement_1): 4618.

https://doi.org/10.1182/blood-2019-129792

Published: 2019

Journal Articles

Management of Cytopenias in CTLA4 Haploinsufficiency Using Abatacept and Sirolimus

Gulbu Uzel, MD, Djuro Karanovic, MD, Hua Su, PhD, Amy Rump, Anahita Agharahimi, Steven M. Holland, MD, V. Koneti Rao, MD FRCPA

Blood (2018) 132 (Supplement 1): 2409.

https://doi.org/10.1182/blood-2018-99-120185

Published: 2018

Journal Articles

Targeting Immune Dysregulation in Childhood Evans Syndrome

Amanda Bell Grimes, MD, Taylor Kim, MD, Susan E. Kirk, PA-C, Michele P. Lambert, MD, Rachael F. Grace, MD, Jenny M. Despotovic, DO, MS

Blood (2018) 132 (Supplement 1): 3564.

https://doi.org/10.1182/blood-2018-99-110734

Published: 2018

Journal Articles

CD28 Induces Metabolic Fitness in Multiple Myeloma for ROS-Dependent Survival

Adam Utley, BS, BA, Peng Peng, Wensheng Liu, Daniella Ventrone, Kelvin P. Lee, MD

Blood (2018) 132 (Supplement 1): 3220.

https://doi.org/10.1182/blood-2018-99-119496

Published: 2018

Journal Articles

Replacement of Polyclonal Anti-Thymocyte Globulin By Targeted Immunomodulation Is Associated with Improved Outcome of Alfa\Beta T Cell-Depleted Hematopoietic Stem Cells Transplantation in Children with Acute Leukemia

Blood (2018) 132 (Supplement 1): 481.

https://doi.org/10.1182/blood-2018-99-116007

Published: 2018

Journal Articles

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Pediatric Leukemia

Blood (2018) 132 (Supplement 1): 2084.

https://doi.org/10.1182/blood-2018-99-116355

Published: 2018

Journal Articles

Phase 1 clinical trial evaluating abatacept in patients with steroid-refractory chronic graft-versus-host disease

Blood (2018) 131 (25): 2836–2845.

https://doi.org/10.1182/blood-2017-05-780239

Published: 2018

Includes: Supplemental data

Journal Articles

CTLA4Ig Primed Donor Lymphocyte Infusions (DLI): A Novel Approach to Natural Killer Cell Immunotherapy Following Haploidentical PBSC Transplantation for Advanced Hematological Malignancies

Sarita Rani Jaiswal, MD BSc, Prakash Bhakuni, Priyanka Bharadwaj, Shamsuz Zaman, MD, Suparno Chakrabarti, MD MD FRCPath

Blood (2017) 130 (Supplement 1): 4468.

https://doi.org/10.1182/blood.V130.Suppl_1.4468.4468

Published: 2017

Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Blood (2017) 130 (Supplement 1): 212.

https://doi.org/10.1182/blood.V130.Suppl_1.212.212

Published: 2017

Journal Articles

Phase I Clinical Trial Evaluating Abatacept in Patient with Steroid-Refractory Chronic Graft Versus Host Disease

Blood (2016) 128 (22): 387.

https://doi.org/10.1182/blood.V128.22.387.387

Published: 2016

Journal Articles

Thrombopoietin-Receptor Agonist in Systemic Lupus Erythematosus Associated Immune Thrombocytopenia: Results of the 16 Patients from the French Cohort

Louis Terriou, MD, Zelie Guitton, MD, Miguel Hie, MD, Zahir Amoura, MD MSc, James B. Bussel, MD, Mohamed Hamidou, MD PhD, Eric Rosenthal, MD, jean-Christophe Lega, MD, Raphaele nove-Josserand, MD, Bertrand Lioger, MD, Axel Chaminade, MD, Nadine magy-Bertrand, MD PhD, Sylvain Audia, MD PhD, Matthieu Mahevas, MD PhD, Bertrand Godeau, MD PhD

Blood (2016) 128 (22): 2542.

https://doi.org/10.1182/blood.V128.22.2542.2542

Published: 2016

Journal Articles

Preclinical Study for the Use of Abatacept to Prevent Rejection of Allogeneic CD34+ Cells in a Xenograft Model

Annie L. Oh, MD, Dolores Mahmud, PhD, Vitalyi Senyuk, PhD, Elisa Bonetti, PhD, Nadim Mahmud, MD PhD, Pritesh R. Patel, MB, ChB, Damiano Rondelli, MD

Blood (2015) 126 (23): 4271.

https://doi.org/10.1182/blood.V126.23.4271.4271

Published: 2015

Journal Articles

Pure Red Cell Aplasia - a New Manifestation of CTLA4 Mutation

Ingunn Dybedal, MDPhD, Anna Mari Lone, PhD, Hanne Sørmo Sorte, MSc, Lorant Farkas, MD PhD, Jürgen Rolke, MD, Robert Brudevold, MD, Asbjørg Stray-Pedersen, MD PhD, Kjetil Tasken, MD PhD

Blood (2015) 126 (23): 2225.

https://doi.org/10.1182/blood.V126.23.2225.2225

Published: 2015

Journal Articles

Impact of STAT3 Mutations on Clinical Features and Treatment Outcomes in Large Granular Lymphocyte Leukemia

Srinivasa Reddy Sanikommu, MD, Michael Clemente, MS, Peter Chomczynski, Swapna Thota, MD, Bhumika J. Patel, Aziz Nazha, MD, Bartlomiej Przychodzen, MSc, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2015) 126 (23): 2216.

https://doi.org/10.1182/blood.V126.23.2216.2216

Published: 2015

NARROW

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Acute Leukemia in Children

Abatacept Is Effective for Gvhd Prophylaxis after Unrelated Donor Stem Cell Transplantation (URD SCT) for Severe Sickle Cell Disease (SCD)

Haploidentical Stem Cell Transplantation with TCR Alpha/Beta and CD19 Depletion in Adult Patients with Hematological Malignancies

Itolizumab As a Potential Therapeutic for the Prevention and Treatment of Graft Vs Host Disease

Flow Cytometry-Based Pre-Transplant Minimal Residual Disease Detection Strongly Impacts on the Outcome of Haploidentical Transplantation with Αβ T Cell Depletion in Pediatric Acute Lymphoblastic Leukemia

Management of Cytopenias in CTLA4 Haploinsufficiency Using Abatacept and Sirolimus

Targeting Immune Dysregulation in Childhood Evans Syndrome

CD28 Induces Metabolic Fitness in Multiple Myeloma for ROS-Dependent Survival

Replacement of Polyclonal Anti-Thymocyte Globulin By Targeted Immunomodulation Is Associated with Improved Outcome of Alfa\Beta T Cell-Depleted Hematopoietic Stem Cells Transplantation in Children with Acute Leukemia

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Pediatric Leukemia

Phase 1 clinical trial evaluating abatacept in patients with steroid-refractory chronic graft-versus-host disease

CTLA4Ig Primed Donor Lymphocyte Infusions (DLI): A Novel Approach to Natural Killer Cell Immunotherapy Following Haploidentical PBSC Transplantation for Advanced Hematological Malignancies

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Phase I Clinical Trial Evaluating Abatacept in Patient with Steroid-Refractory Chronic Graft Versus Host Disease

Thrombopoietin-Receptor Agonist in Systemic Lupus Erythematosus Associated Immune Thrombocytopenia: Results of the 16 Patients from the French Cohort

Preclinical Study for the Use of Abatacept to Prevent Rejection of Allogeneic CD34+ Cells in a Xenograft Model

Pure Red Cell Aplasia - a New Manifestation of CTLA4 Mutation

Impact of STAT3 Mutations on Clinical Features and Treatment Outcomes in Large Granular Lymphocyte Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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