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Larisa Shelikhova
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Journal Articles

Donor-Derived CAR-T Cells in Children with B-Lineage Acute Lymphoblastic Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation: Report of 20 Cases

Larisa Shelikhova, Olga Molostova, Maria Klimentova, Rimma Khismatullina, Evelina Lyudovskikh, Svetlana Kozlovskaya, Yulia Abugova, Dmitriy Pershin, Victoria Vedmedskaya, Maria Fadeeva, Ekaterina Malakhova, Lili Khachatryan, Yakov Muzalevskii, Alexey Kazachenok, Alexander Popov, Ekaterina Mikhailova, Dmitriy Litvinov, Galina Novichkova, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2024) 144 (Supplement 1): 7218.
https://doi.org/10.1182/blood-2024-205696
Published: 2024
Journal Articles

Post-Transplant Cyclophosphamide, Abatacept, and Vedolizumab to Prevent Graft-Versus-Host Disease after Hematopoietic Stem Cells Transplantation from Haploidentical Donors in Children with Acute Leukemia: Results of a Prospective Trial

Larisa Shelikhova, Margarita Perminova, Olga Molostova, Maria Ilushina, Rimma Khismatullina, Dmitriy Balashov, Natalia Miakova, Julia Skvortsova, Maria Dunaikina, Svetlana Radygina, Galina Novichkova, Svetlana Kozlovskaya, Sergei Blagov, Elena Kurnikova, Anna Livshits, Dmitriy Pershin, Dmitriy Litvinov, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3555.
https://doi.org/10.1182/blood-2023-182895
Published: 2023
Journal Articles

Allogeneic Donor-Derived Myeloid Antigen Directed CAR-T Cells - for Relapsed/Refractory Acute Myeloid Leukemia in Children after Allogeneic Hematopoietic Stem Cell Transplantation: Report of Three Cases

Larisa Shelikhova, Arina Rakhteenko, Olga Molostova, Elena Kurnikova, V. Ukrainskaya, Yakov Muzalevsky, Dmitry Pershin, Alexander Popov, Elena Kulakovskaya, Dina Baidildina, Alexey Stepanov, Elena Osipova, Galina Novichkova, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2022) 140 (Supplement 1): 4600–4601.
https://doi.org/10.1182/blood-2022-168891
Published: 2022
Journal Articles

Tcrαβ+/CD19+-Depletion in Hematopoietic Stem Cells Transplantation from Matched Unrelated and Haploidentical Donors in Pediatric Acute Lymphoblastic Leukemia Patients in Complete Remission

Larisa Shelikhova, Rimma Khismatullina, Dmitriy Balashov, Alexey Kazachenok, Yakov Muzalevsky, Julia Abugova, Julia Skvortsova, Alexander Popov, Dmitry Pershin, Daria Kobyzeva, Alexey Nechesnyuk, Yulia Olshanskaya, Svetlana Kozlovskaya, Sergey Blagov, Natalia Miakova, Galina Novichkova, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2022) 140 (Supplement 1): 2113–2114.
https://doi.org/10.1182/blood-2022-168605
Published: 2022
Journal Articles

CD19 CAR-T Cell Therapy in Children with Relapsed and Refractory B-ALL

Olga Molostova, Larisa Shelikhova, Yakov Muzalevsky, Alexey Kazachenok, Rimma Khismatullina, Julia Abugova, Elena Kurnikova, Pavel Trakhtman, Dmitry Pershin, Viktoria Zubachenko, Maria Fadeeva, Alexander M Popov, Olga Illarionova, Natalia Miakova, Dmitry Litvinov, Galina Novichkova, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1737.
https://doi.org/10.1182/blood-2021-153414
Published: 2021
Journal Articles

Haploidentical Donor-Derived CAR-T Cells Are Safely and Effectively Co-Infused with the Haploidentical Graft, Depleted of Ab T Cells: Report of Case Series

Larisa Shelikhova, Olga Molostova, Arina Rakhteenko, Rimma Khismatullina, Julia Abugova, Elena Kurnikova, Yakov Muzalevsky, Alexey Kazachenok, Dmitry Pershin, Maria Fadeeva, Alexander M Popov, Olga Illarionova, Natalia Miakova, Dmitry Litvinov, Galina Novichkova, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1736.
https://doi.org/10.1182/blood-2021-153343
Published: 2021
Journal Articles

Results of Hematopoietic Stem Cells Transplantation with Tcrαβ and CD19-Depletion from Matched Related Donors and Infusions of CD45RA Depleted Donor Lymphocytes in Pediatric Severe Aplastic Anemia

Larisa Shelikhova, Anna Bogoyavlenskaya, Maria Ilushina, Tatiana Salimova, Kristina Antonova, Julia Skvortsova, Daria Shasheleva, Svetlana Radygina, Elvira Sultanova, Svetlana Glushkova, Ruslan Nikolaev, Elena Kurnikova, Dmitry Pershin, Yakov Muzalevsky, Alexey Kazachenok, Elena Osipova, Dmitriy Balashov, Galina Novichkova, Alexey Maschan, Michael Maschan
Journal: Blood
Blood (2021) 138 (Supplement 1): 558.
https://doi.org/10.1182/blood-2021-152769
Published: 2021
Journal Articles

Total Body Irradiation Among Recipients of Tcrαβ /CD19- Depleted Grafts in a Cohort of Children with Hematologic Malignances: Single Center Experience

Daria Kobyzeva, MD, Larisa Shelikhova, PhD, Zhanna Shekhovtsova, MD, Rimma Khismatullina, MD, Maria Ilushina, MD, Anna Loginova, Alexey Nechesnuyk, PhD, Michael Maschan, PhDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 2.
https://doi.org/10.1182/blood-2020-139282
Published: 2020
Journal Articles

Mismatched related vs matched unrelated donors in TCRαβ/CD19-depleted HSCT for primary immunodeficiencies

Alexandra Laberko, Elvira Sultanova, Elena Gutovskaya, Irina Shipitsina, Larisa Shelikhova, Elena Kurnikova, Yakov Muzalevskii, Alexei Kazachenok, Dmitriy Pershin, Kirill Voronin, Anna Shcherbina, Michael Maschan, Alexey Maschan, Dmitry Balashov
Journal: Blood
Blood (2019) 134 (20): 1755–1763.
https://doi.org/10.1182/blood.2019001757
Published: 2019
Includes: Supplemental data
Journal Articles

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Acute Leukemia in Children

Larisa Shelikhova, MD, Rimma Khismatullina, MD, Michael Maschan, MD MSc, Alexey A. Maschan, MD, Irina Kalinina, MD, Elena Kurnikova, Yakov Muzalevsky, Alexey Kazachenok, Dmitriy Pershin, Alexander Popov, MD PhD, Galina Novichkova, MD PhD, Dmitriy Balashov, MD PhD, Daria Shasheleva, MD, Svetlana Kashpor, Evgeny Gluhanyuk
Journal: Blood
Blood (2019) 134 (Supplement_1): 150.
https://doi.org/10.1182/blood-2019-129765
Published: 2019
Journal Articles

Local Manufacture of CD19 CAR-T Cells Using an Automated Closed-System: Robust Manufacturing and High Clinical Efficacy with Low Toxicities

Olga Molostova, MD, Larisa Shelikhova, MD, Dina Schneider, PhD, Rimma Khismatullina, MD, Yakov Muzalevsky, Alexey Kazachenok, Liane Preussner, Georg Rauser, Julia Abugova, Elena Kurnikova, Dmitriy Pershin, Viktoria Zubachenko, Alexander Popov, MD PhD, Olga Illarionova, MD, Natalia Miakova, MD PhD, Dmitry Litvinov, MD, Galina Novichkova, MD PhD, Alexey A. Maschan, MD, Rimas Orentas, PhD, Boro Dropulic, PhD, Michael Maschan, MDMSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2625.
https://doi.org/10.1182/blood-2019-130370
Published: 2019
Journal Articles

Flow Cytometry-Based Pre-Transplant Minimal Residual Disease Detection Strongly Impacts on the Outcome of Haploidentical Transplantation with Αβ T Cell Depletion in Pediatric Acute Lymphoblastic Leukemia

Larisa Shelikhova, MD, Maria Ilushina, MD, Alexander Popov, MD PhD, Zhanna Shekhovtsova, MD, Dmitriy Balashov, MD PhD, Alexey Kazachenok, Yakov Muzalevsky, Irina Shipitsina, MD, Daria Shasheleva, MD, Rimma Khismatullina, MD, Elena Kurnikova, Sergey Blagov, MD, Julia Abugova, Anna Bogoyavlenskaya, MD, Daria Kobyzeva, Dmitriy Pershin, Yulia Olshanskaya, MD PhD, Alexey Nechesnyuk, Ekaterina Mikhailova, Maria Fadeeva, Natalia Miakova, MD PhD, Dmitry Litvinov, MD, Galina Novichkova, Alexey A. Maschan, MD, Michael Maschan, MDMSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 4618.
https://doi.org/10.1182/blood-2019-129792
Published: 2019
Journal Articles

Title Point-of-Care Production of CD19 CAR-T Cells in an Automated Closed-System: Report of First Clinical Experience

Olga Molostova, MD, Larisa Shelikhova, MD, Yakov Muzalevsky, Alexey Kazachenok, Dmitriy Pershin, Elena Kurnikova, Alexander Popov, MD PhD, Boro Dropulic, PhD, Dina Shneider, Rimas Orentas, PhD, Regina Alex, Mike Essl, Natalia Miakova, MD PhD, Dmitry Litvinov, MD PhD, Alexander Karachunskiy, MD PhD, Galina Novichkova, MD PhD, Alexey A. Maschan, MD, Michael Maschan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5202.
https://doi.org/10.1182/blood-2018-99-118282
Published: 2018
Journal Articles

Replacement of Polyclonal Anti-Thymocyte Globulin By Targeted Immunomodulation Is Associated with Improved Outcome of Alfa\Beta T Cell-Depleted Hematopoietic Stem Cells Transplantation in Children with Acute Leukemia

Larisa Shelikhova, MD, Maria Ilushina, MD, Dmitriy Balashov, MDPhD, Zhanna Shekhovtsova, MD, Irina Shipitsina, MD, Daria Shasheleva, MD, Rimma Khismatullina, MD, Elena Gutovskaya, MD, Anna Bogoyavlenskaya, MD, Sergey Blagov, MD, Svetlana Kozlovskaya, MD, Elena Kurnikova, Yakov Muzalevsky, Alexey Kazachenok, Dmitriy Pershin, Maria Fadeeva, Yulia Olshanskaya, MD PhD, Alexey Nechesnyuk, Irina Kalinina, MD, Natalia Miakova, MD PhD, Dmitry Litvinov, MD PhD, Galina Novichkova, MDPhD, Alexey A. Maschan, MD, Michael Maschan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 481.
https://doi.org/10.1182/blood-2018-99-116007
Published: 2018
Journal Articles

Targeting Bcl-2 and CD38 As Part of Personalized HSCT Conditioning Regimen in Chemorefractory Pediatric Leukemia

Maria Alyabeva, MD, Larisa Shelikhova, MD, Larisa Shelikhova, Daria Shasheleva, MD, Rimma Khismatullina, MD, Svetlana Radygina, MD, Anna Bogoyavlenskaya, MD, Sergey Blagov, MD, Olga Molostova, MD, Svetlana Kozlovskaya, MD, Irina Kalinina, MD, Elena Kurnikova, Yakov Muzalevsky, Dmitriy Pershin, Alexander Popov, MD PhD, Olga Illarionova, MD, Yulia Olshanskaya, MD PhD, Natalia Miakova, MD PhD, Dmitry Litvinov, MD PhD, Galina Novichkova, MD PhD, Alexey A. Maschan, MD, Michael Maschan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2084.
https://doi.org/10.1182/blood-2018-99-116355
Published: 2018
Journal Articles

Alpha/Beta T Cell Depleted Haploidentical Transplantation Results in High Survival in Pediatric Patients with Acute Myeloid Leukemia

Larisa Shelikhova, Maria Ilushina, Zhanna Shekhovtsova, MD, Elena Kurnikova, Galina Novichkova, Alexey A Maschan, MD PhD Professor, Michael Maschan, MDMSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 4580.
https://doi.org/10.1182/blood.V130.Suppl_1.4580.4580
Published: 2017
Journal Articles

T Cell Repertoire after Alpha/Beta-T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients

Ivan Zvyagin, PhD, Olga Tatarinova, Ilgar Mamedov, PhD, Ekaterina Komech, Alexey Maschan, MD PhD, Larisa Shelikhova, MD, Elena Kurnikova, MD, Elena Boyakova, MD, Yuri Lebedev, PhD DSc, Michael Maschan, MD PhD, Dmitry Chudakov, PhD DSc
Journal: Blood
Blood (2016) 128 (22): 4582.
https://doi.org/10.1182/blood.V128.22.4582.4582
Published: 2016
Journal Articles

Tcrαβ+/CD19+-Depletion in Hematopoietic Stem Cells Transplantation from Matched Unrelated and Haploidentical Donors Following Treosulfan or TBI-Based Conditioning in Pediatric Acute Lymphoblastic Leukemia Patients

Larisa Shelikhova, MD, Zhanna Shekhovtsova, MD, Dmitry Balashov, Elena Boyakova, Iakov Muzalevskyi, Elena Gutovskaya, Irina Shipitsina, Daria Shasheleva, Rimma Khismatullina, Sergey Blagov, Natalia Myakova, Andrey Abrosimov, Galina Novichkova, MD, Alexey Maschan, MD PhD, Michael Maschan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4672.
https://doi.org/10.1182/blood.V128.22.4672.4672
Published: 2016
Journal Articles

Transplantation from Matched Unrelated and Haploidentical Donor in Pediatric Severe Aplastic Anemia: Experience with TCR Alpha/Beta and CD19 Depletion As Graft Processing Method

Daria Shasheleva, Larisa Shelikhova, MD, Zhanna Shekhovtsova, MD, Dmitriy Balashov, Pavel Trakhtman, Elena Boyakova, MD, Elena Raykina, Elena Kurnikova, MD, Alexey Kazachenok, Varvara Briliantova, Anna Bogoyavlenskaya, Maria Ilyushina, Svetlana Kozlovskaya, Galina Novichkova, MD, Michael Maschan, MD PhD, Alexey Maschan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2294.
https://doi.org/10.1182/blood.V128.22.2294.2294
Published: 2016
Journal Articles

Improved Control of GvHD with Rabbit ATG, Rituximab and Bortezomib Among Pediatric Leukemia Patients after Tcrαβ/CD19-Depletion of Transplant from Matched Unrelated and Haploidentical Family Donors: A Single-Center Retrospective Analysis of Two Gvhd-Prophylaxis Regimens

Zhanna Shekhovtsova, MD, Larisa Shelikhova, MD, Dmitry Balashov, Elena Kurnikova, MD, Iakov Muzalevskyi, Alexey Kazachenok, Yuliya Skvortsova, Maria Ilyushina, Daria Shasheleva, Rimma Khismatullina, Sergey Blagov, Dmitry Litvinov, MD PhD, Galina Novichkova, MD, Alexey Maschan, MD PhD, Julia Starichkova, Michael Maschan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3427.
https://doi.org/10.1182/blood.V128.22.3427.3427
Published: 2016