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Journal Articles

TGF-β Pathway Inhibition Improves Hematopoietic Deficiency and Immune Imbalance By Repairing Endothelial Progenitor Cell Function in Aplastic Anemia

Xinyan Zhang, Li-Ping Guo, Jin-Song Jia, Ya-Zhe Wang, Mi Liang, Mengzhu Shen, Zhenkun Wang, Chen-Yuan Li, Zhong-Shi Lyu, Tong Xing, Zhi-Wei Zhang, Yuan-Yuan Zhang, Xiao-Jun Huang, Yuan Kong

Blood (2024) 144 (Supplement 1): 4074.

https://doi.org/10.1182/blood-2024-201438

Published: 2024

Journal Articles

Inhibition of TGF-β in Bone Marrow Endothelial Progenitor Cells Promotes Hematopoietic Recovery in Acute Myeloid Leukemia after Chemotherapy

Zhenkun Wang, Zhi-Wei Zhang, Zhong-Shi Lyu, Tong Xing, Mi Liang, Mengzhu Shen, Chen-Yuan Li, Xin-Yan Zhang, Dan-Dan Chen, Ya-Zhe Wang, Li-Juan Hu, Hao Jiang, Qian Jiang, Yuan Kong, Xiao-Jun Huang

Blood (2024) 144 (Supplement 1): 2684.

https://doi.org/10.1182/blood-2024-201354

Published: 2024

Journal Articles

Successful Toxicity Reduction in Ma-Spore ALL 2010 in Standard/Intermediate Risk Childhood ALL: Replacing Cytarabine/Doxorubicin with More Vincristine and L-Asparaginase during Consolidation and Delayed Intensification

Bernice Oh, MBBS, MRCP, Shawn Lee, MD, Zelia Seeto, Germaine Liew, Bsc, Edwynn Chiew, MBBS, Zhi Wei Chen, Bsc, Yiong Huak Chan, PhD, Jing Jia Eng, Bsc, Koon Mian Foo, Bsc, Ching Mei Joyce Lam, MD, Ah Moy Tan, MD, Allen Eng Juh Yeoh, MD

Blood (2019) 134 (Supplement_1): 1307.

https://doi.org/10.1182/blood-2019-122098

Published: 2019

Journal Articles

Distinct gene-expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection

Haitao Hu, Martin Nau, Phil Ehrenberg, Agnes-Laurence Chenine, Camila Macedo, Yu Zhou, Z. John Daye, Zhi Wei, Maryanne Vahey, Nelson L. Michael, Jerome H. Kim, Mary Marovich, Silvia Ratto-Kim

Blood (2013) 121 (7): 1136–1144.

https://doi.org/10.1182/blood-2012-07-446278

Published: 2013

Includes: Supplemental data

Journal Articles

Lycorine Modulates the Expression of p21 Via a p53-Independent Pathway in HL-60 Cells

Jing Liu, Shu-Ling Wang, Lin Fang, Mao Ye, Zhi-Wei Sun, Lv Li, Zi Wang, Hui-Wen Yan, Sai-Qun Luo, Hui-Yong Chen, Xiuli An, MD, PhD, Wei-Xin Hu

Blood (2011) 118 (21): 4297.

https://doi.org/10.1182/blood.V118.21.4297.4297

Published: 2011

Journal Articles

Anti-Myeloma and Anti-Angiogenic Effects of the Novel Anthracycline Derivative INNO-206

Eric Sanchez, Mingjie Li, Cathy Wang, Alex de Castro Abeger, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2010) 116 (21): 4065.

https://doi.org/10.1182/blood.V116.21.4065.4065

Published: 2010

Journal Articles

Efficacy and Tolerability of CEP-18770 In Combination with Dexamethasone and Lenalidomide Using a SCID-Hu Model of Multiple Myeloma (MM)

Eric Sanchez, Mingjie Li, Cathy Wang, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2010) 116 (21): 4066.

https://doi.org/10.1182/blood.V116.21.4066.4066

Published: 2010

Journal Articles

Multiple Myeloma (MM) Highly Expresses CGEN-928 and the Anti-CGEN-928 TM21 Antibody Markedly Inhibits the Growth of MM Cells and Enhances the Anti-Myeloma Effects of Dexamethasone, Melphalan and Bortezomib

Haiming Chen, MD, PhD, Mingjie Li, Cathy Wang, Jessica Wang, Eric Sanchez, Zhi-Wei Li, PhD, Benjamin Bonavida, PhD, Ofer Levy, Liat Dassa, Gady Cojocaru, MD, James R. Berenson, MD, Zurit Levine, PhD

Blood (2010) 116 (21): 4067.

https://doi.org/10.1182/blood.V116.21.4067.4067

Published: 2010

Journal Articles

Blockage of TRAF6 by Dominant Negative Peptides to Inhibit Multiple Myeloma (MM) Cell Proliferation and Osteoclast Formation through NF-κB, JNK and AKT Signal Transduction Pathways

Mingjie Li, Eric Sanchez, Cathy Wang, Megan Schultz, Jessica Wang, Emily Wong, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, Benjamin Bonavida, PhD, Eddie E Chou, James R. Berenson, MD

Blood (2010) 116 (21): 4068.

https://doi.org/10.1182/blood.V116.21.4068.4068

Published: 2010

Journal Articles

Lack of Binding of Monoclonal Protein Produced by Multiple Myeloma (MM) Cells to FcγRIIb Reduces Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Signaling and Provides the Rationale for a Novel Therapeutic Approach to MM

Jennifer Li, Mingjie Li, Cathy Wang, Jessica Wang, Eric Sanchez, Zhi-Wei Li, PhD, Benjamin Bonavida, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2010) 116 (21): 455.

https://doi.org/10.1182/blood.V116.21.455.455

Published: 2010

Journal Articles

Using SCID-Hu Models to Evaluate the Sequencing of Bortezomib Therapy for Multiple Myeloma (MM)

Eric Sanchez, PhD, Mingjie Li, PhD, Cathy Wang, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, Jacqueline Hilger, MS, Barbara Hibner, PhD, James R. Berenson, MD

Blood (2010) 116 (21): 5012.

https://doi.org/10.1182/blood.V116.21.5012.5012

Published: 2010

Journal Articles

Synergistic Anti-Myeloma Effects of the Lyn Kinase Inhibitor INNO-406 In Combination with Doxorubicin, Melphalan and Bortezomib

Zhi-Wei Li, PhD, Eric Sanchez, Cathy Wang, Mingjie Li, David Ramirez, Cydney Nichols, Jennifer Li, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2010) 116 (21): 5015.

https://doi.org/10.1182/blood.V116.21.5015.5015

Published: 2010

Journal Articles

An evolutionarily conserved PTEN-C/EBPα-CTNNA1 axis controls myeloid development and transformation

Blood (2010) 115 (23): 4715–4724.

https://doi.org/10.1182/blood-2009-11-255778

Published: 2010

Includes: Supplemental data

Journal Articles

Multiple Myeloma-Specific Targeted Therapy: Use of the Tumor Specific Immunoglobulin Gene Sequence to Activate Drugs Only within Tumor Cells.

Zhi-Wei Li, PhD, Dror Shalitin, PhD, Jennifer Finefield, Crystal Leung, Mengyin Hu, Jing Shen, Mingjie Li, Cathy S Wang, Jeffrey A Steinberg, Eric Sanchez, Haiming Chen, MD, PhD, Robert M Williams, PhD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2009) 114 (22): 1851.

https://doi.org/10.1182/blood.V114.22.1851.1851

Published: 2009

Journal Articles

Oral Dosing of the Novel Proteasome Inhibitor CEP-18770 Shows Marked Anti-Myeloma Effects in SCID-Hu Models of Multiple Myeloma.

Eric Sanchez, Mingjie Li, Jeffrey A Steinberg, Cathy S Wang, Jing Shen, Benjamin Bonavida, PhD, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2009) 114 (22): 1840.

https://doi.org/10.1182/blood.V114.22.1840.1840

Published: 2009

Journal Articles

Alpha Lipoic Acid (ALA) Inhibits the Anti-Myeloma Effects of Bortezomib.

Jeffrey A Steinberg, Jing Shen, Eric Sanchez, Haiming Chen, MD, PhD, Zhi-Wei Li, PhD, Jacqueline Hilger, MS, James R. Berenson, MD

Blood (2009) 114 (22): 3832.

https://doi.org/10.1182/blood.V114.22.3832.3832

Published: 2009

Journal Articles

Largazole, a Novel Cyclic Peptide Histone Deacetylase Inhibitor, Demonstrates Anti-MM Effects Alone and Increases the Anti-MM Effects of Bortezomib.

Zhi-Wei Li, PhD, Mengyin Hu, Crystal Leung, Jeffrey A Steinberg, Jing Shen, Mingjie Li, Cathy S Wang, Eric Sanchez, Albert Bowers, Thomas Greshock, Kenneth Miller, Tenaya Newkirk, Nathan West, James E. Bradner, MD, Robert M Williams, PhD, Benjamin Bonavida, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD

Blood (2009) 114 (22): 4925.

https://doi.org/10.1182/blood.V114.22.4925.4925

Published: 2009

Journal Articles

CC102528: A Novel Histone Deacetylase Inhibitor in the Hydroxamate Family Demonstrates Potent Anti-Myeloma Activity.

Zhi-Wei Li, PhD, Crystal Leung, Mengyin Hu, Jinbao Xiang, Chao Jiang, Jeffrey A Steinberg, Jing Shen, Mingjie Li, Cathy S Wang, Eric Sanchez, Benjamin Bonavida, PhD, Haiming Chen, MD, PhD, Xu Bai, James R. Berenson, MD

Blood (2009) 114 (22): 4927.

https://doi.org/10.1182/blood.V114.22.4927.4927

Published: 2009

Journal Articles

TRAF6-Dominant Negative Peptides Show Potent Inhibitory Effects On Multiple Myeloma, Osteoclast Formation and Bone Resorption.

Mingjie Li, Eric Sanchez, Jennifer Li, Cathy S Wang, Jing Shen, Mengyin Hu, Crystal Leung, Jessica Wang, Emily Wong, Anoushka Adler, Zhi-Wei Li, PhD, Haiming Chen, MD, PhD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2009) 114 (22): 611.

https://doi.org/10.1182/blood.V114.22.611.611

Published: 2009

Journal Articles

Pterostilbene: A Novel Histone Deacetylase 1 Inhibitor (HDACi1) Demonstrating Efficacy in Multiple Myeloma.

Haiming Chen, MD, PhD, Rui Hao, PhD, Eric Sanchez, Jing Shen, Mingjie Li, Jessica Wang, Emily Wong, Anoushka Adler, Mengyin Hu, Crystal Leung, Cathy S Wang, Zhi-Wei Li, PhD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2009) 114 (22): 3844.

https://doi.org/10.1182/blood.V114.22.3844.3844

Published: 2009

NARROW

TGF-β Pathway Inhibition Improves Hematopoietic Deficiency and Immune Imbalance By Repairing Endothelial Progenitor Cell Function in Aplastic Anemia

Inhibition of TGF-β in Bone Marrow Endothelial Progenitor Cells Promotes Hematopoietic Recovery in Acute Myeloid Leukemia after Chemotherapy

Successful Toxicity Reduction in Ma-Spore ALL 2010 in Standard/Intermediate Risk Childhood ALL: Replacing Cytarabine/Doxorubicin with More Vincristine and L-Asparaginase during Consolidation and Delayed Intensification

Distinct gene-expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection

Lycorine Modulates the Expression of p21 Via a p53-Independent Pathway in HL-60 Cells

Anti-Myeloma and Anti-Angiogenic Effects of the Novel Anthracycline Derivative INNO-206

Efficacy and Tolerability of CEP-18770 In Combination with Dexamethasone and Lenalidomide Using a SCID-Hu Model of Multiple Myeloma (MM)

Multiple Myeloma (MM) Highly Expresses CGEN-928 and the Anti-CGEN-928 TM21 Antibody Markedly Inhibits the Growth of MM Cells and Enhances the Anti-Myeloma Effects of Dexamethasone, Melphalan and Bortezomib

Blockage of TRAF6 by Dominant Negative Peptides to Inhibit Multiple Myeloma (MM) Cell Proliferation and Osteoclast Formation through NF-κB, JNK and AKT Signal Transduction Pathways

Lack of Binding of Monoclonal Protein Produced by Multiple Myeloma (MM) Cells to FcγRIIb Reduces Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Signaling and Provides the Rationale for a Novel Therapeutic Approach to MM

Using SCID-Hu Models to Evaluate the Sequencing of Bortezomib Therapy for Multiple Myeloma (MM)

Synergistic Anti-Myeloma Effects of the Lyn Kinase Inhibitor INNO-406 In Combination with Doxorubicin, Melphalan and Bortezomib

An evolutionarily conserved PTEN-C/EBPα-CTNNA1 axis controls myeloid development and transformation

Multiple Myeloma-Specific Targeted Therapy: Use of the Tumor Specific Immunoglobulin Gene Sequence to Activate Drugs Only within Tumor Cells.

Oral Dosing of the Novel Proteasome Inhibitor CEP-18770 Shows Marked Anti-Myeloma Effects in SCID-Hu Models of Multiple Myeloma.

Alpha Lipoic Acid (ALA) Inhibits the Anti-Myeloma Effects of Bortezomib.

Largazole, a Novel Cyclic Peptide Histone Deacetylase Inhibitor, Demonstrates Anti-MM Effects Alone and Increases the Anti-MM Effects of Bortezomib.

CC102528: A Novel Histone Deacetylase Inhibitor in the Hydroxamate Family Demonstrates Potent Anti-Myeloma Activity.

TRAF6-Dominant Negative Peptides Show Potent Inhibitory Effects On Multiple Myeloma, Osteoclast Formation and Bone Resorption.

Pterostilbene: A Novel Histone Deacetylase 1 Inhibitor (HDACi1) Demonstrating Efficacy in Multiple Myeloma.

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American Society of Hematology

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American Society of Hematology

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