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Z. Ioav Cabantchik
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Journal Articles

Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation

Or Kakhlon, Hila Manning, William Breuer, Naomi Melamed-Book, Chunye Lu, Gino Cortopassi, Arnold Munnich, Z. Ioav Cabantchik
Journal: Blood
Blood (2008) 112 (13): 5219–5227.
https://doi.org/10.1182/blood-2008-06-161919
Published: 2008
Includes: Supplemental data
Journal Articles

Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications

Yang-Sung Sohn, William Breuer, Arnold Munnich, Z. Ioav Cabantchik
Journal: Blood
Blood (2008) 111 (3): 1690–1699.
https://doi.org/10.1182/blood-2007-07-102335
Published: 2008
Journal Articles

Selective iron chelation in Friedreich ataxia: biologic and clinical implications

Nathalie Boddaert, Kim Hanh Le Quan Sang, Agnès Rötig, Anne Leroy-Willig, Serge Gallet, Francis Brunelle, Daniel Sidi, Jean-Christophe Thalabard, Arnold Munnich, Z. Ioav Cabantchik
Journal: Blood
Blood (2007) 110 (1): 401–408.
https://doi.org/10.1182/blood-2006-12-065433
Published: 2007
Journal Articles

Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

Sara Gardenghi, Maria F. Marongiu, Pedro Ramos, Ella Guy, Laura Breda, Amy Chadburn, YiFang Liu, Ninette Amariglio, Gideon Rechavi, Eliezer A. Rachmilewitz, William Breuer, Z. Ioav Cabantchik, Diedra M. Wrighting, Nancy C. Andrews, Maria de Sousa, Patricia J. Giardina, Robert W. Grady, Stefano Rivella
Journal: Blood
Blood (2007) 109 (11): 5027–5035.
https://doi.org/10.1182/blood-2006-09-048868
Published: 2007
Includes: Supplemental data
Journal Articles

Action of chelators in iron-loaded cardiac cells: accessibility to intracellular labile iron and functional consequences

Hava Glickstein, Rinat Ben El, Gabi Link, William Breuer, Abraham M. Konijn, Chaim Hershko, Hanspeter Nick, Z. Ioav Cabantchik
Journal: Blood
Blood (2006) 108 (9): 3195–3203.
https://doi.org/10.1182/blood-2006-05-020867
Published: 2006
Journal Articles

Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells

Hava Glickstein, Rinat Ben El, Maya Shvartsman, Z. Ioav Cabantchik
Journal: Blood
Blood (2005) 106 (9): 3242–3250.
https://doi.org/10.1182/blood-2005-02-0460
Published: 2005
Journal Articles

Redox active plasma iron in C282Y/C282Y hemochromatosis

Clinical Trials & Observations
Caroline Le Lan, Olivier Loréal, Tally Cohen, Martine Ropert, Hava Glickstein, Fabrice Lainé, Michel Pouchard, Yves Deugnier, André Le Treut, William Breuer, Z. Ioav Cabantchik, Pierre Brissot
Journal: Blood
Blood (2005) 105 (11): 4527–4531.
https://doi.org/10.1182/blood-2004-09-3468
Published: 2005
Journal Articles

Labile plasma iron (LPI) as an indicator of chelatable plasma redox activity in iron-overloaded β-thalassemia/HbE patients treated with an oral chelator

Clinical Trials & Observations
Pensri Pootrakul, William Breuer, Matias Sametband, Pornpan Sirankapracha, Chaim Hershko, Z. Ioav Cabantchik
Journal: Blood
Blood (2004) 104 (5): 1504–1510.
https://doi.org/10.1182/blood-2004-02-0630
Published: 2004
Journal Articles

Labile plasma iron in iron overload: redox activity and susceptibility to chelation

Breno P. Esposito, William Breuer, Pornpan Sirankapracha, Pensri Pootrakul, Chaim Hershko, Z. Ioav Cabantchik
Journal: Blood
Blood (2003) 102 (7): 2670–2677.
https://doi.org/10.1182/blood-2003-03-0807
Published: 2003
Journal Articles

Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells

Gabriela Link, Prem Ponka, Abraham M. Konijn, William Breuer, Z. Ioav Cabantchik, Chaim Hershko
Journal: Blood
Blood (2003) 101 (10): 4172–4179.
https://doi.org/10.1182/blood-2002-08-2382
Published: 2003
Journal Articles

Desferrioxamine-chelatable iron, a component of serum non–transferrin-bound iron, used for assessing chelation therapy: Presented in preliminary form at the 10th International Conference on Oral Chelators symposium on iron chelators held in Limassol, Cyprus, March 2000 ( Transfusion Science , in press).

William Breuer, Marieke J. J. Ermers, Pensri Pootrakul, Ayala Abramov, Chaim Hershko, Z. Ioav Cabantchik
Journal: Blood
Blood (2001) 97 (3): 792–798.
https://doi.org/10.1182/blood.V97.3.792
Published: 2001
Journal Articles

The assessment of serum nontransferrin-bound iron in chelation therapy and iron supplementation

William Breuer, Aharon Ronson, Itzchak N. Slotki, Ayala Abramov, Chaim Hershko, Z. Ioav Cabantchik
Journal: Blood
Blood (2000) 95 (9): 2975–2982.
https://doi.org/10.1182/blood.V95.9.2975.009k03_2975_2982
Published: 2000
Journal Articles

H-Ferritin Subunit Overexpression in Erythroid Cells Reduces the Oxidative Stress Response and Induces Multidrug Resistance Properties

Silvina Epsztejn, Hava Glickstein, Virginie Picard, Itzchak N. Slotki, William Breuer, Carole Beaumont, Z. Ioav Cabantchik
Journal: Blood
Blood (1999) 94 (10): 3593–3603.
https://doi.org/10.1182/blood.V94.10.3593.422k26_3593_3603
Published: 1999
Journal Articles

The Cellular Labile Iron Pool and Intracellular Ferritin in K562 Cells

Abraham M. Konijn, Hava Glickstein, Boris Vaisman, Esther G. Meyron-Holtz, Itzchak N. Slotki, Z. Ioav Cabantchik
Journal: Blood
Blood (1999) 94 (6): 2128–2134.
https://doi.org/10.1182/blood.V94.6.2128
Published: 1999