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Yunzhu Dong
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Journal Articles

Global Crosstalk between Two Histone Modifications That Control Transcriptional Elongation in MLL Leukemia

Jiachen Bu, Aili Chen, PhD, Xiaomei Yan, Fuhong He, PhD, Yunzhu Dong, Yile Zhou, Jianlin He, Yoshihiro Hayashi, Di Zhan, Yanling Sun, Yue Zhang, Zhijian Xiao, Lee Grimes, Qianfei Wang, PhD, Gang Huang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2495.
https://doi.org/10.1182/blood.V130.Suppl_1.2495.2495
Published: 2017
Journal Articles

Downregulation of SETD2-H3K36me3 Tumor Suppression Axis Promotes MLL Leukemia through Activation of DOT1L-H3K79me2 Axis

Jiachen Bu, Aili Chen, PhD, Yunzhu Dong, PhD, Fuhong He, PhD, Xiaomei Yan, MD PhD, Yile Zhou, Di Zhan, Yoshihiro Hayashi, MD PhD, Qianfei Wang, PhD, Gang Huang, PhD
Journal: Blood
Blood (2016) 128 (22): 435.
https://doi.org/10.1182/blood.V128.22.435.435
Published: 2016
Journal Articles

SETD2, a H3K36 Lysine Methyltransferase, Is Essential for Adult Normal Hematopoiesis and Leukemia Stem Cells

Yile Zhou, Yunzhu Dong, Jiachen Bu, Xiaomei Yan, MD PhD, Yoshihiro Hayashi, MD PhD, Qianfei Wang, PhD, Jie Jin, MD PhD, Gang Huang, PhD
Journal: Blood
Blood (2016) 128 (22): 1055.
https://doi.org/10.1182/blood.V128.22.1055.1055
Published: 2016
Journal Articles

Two Novel Knock-in and Knock-out of Setd2 Alleles Cooperate with Mll-Af9 Knock-in Allele to Accelerate Leukemia Development

Yunzhu Dong, Yoshihiro Hayashi, MD PhD, Xiaomei Yan, MD PhD, Feng Xue, PhD, Wei Chen, PhD, Gang Huang, PhD
Journal: Blood
Blood (2015) 126 (23): 555.
https://doi.org/10.1182/blood.V126.23.555.555
Published: 2015
Journal Articles

HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development

Yoshihiro Hayashi, MD PhD, Yue Zhang, MD, Xiaomei Yan, MD PhD, Kwangmin Choi, PhD, Goro Sashida, MD PhD, Yunzhu Dong, Zefeng Xu, MD, Lingyun Wu, MD PhD, Aili Chen, PhD, Xiujuan Sun, MD, Andre Olsson, PhD, Hironori Harada, MD PhD, Lee-Yung Shih, MD, William Tse, MD FACP, James Bridges, PhD, David P Witte, MD, Qianfei Wang, Michael A. Caligiuri, MD, H. Leighton Grimes, PhD, Stephen D. Nimer, MD, Zhijian Xiao, MD, Gang Huang, PhD
Journal: Blood
Blood (2015) 126 (23): 303.
https://doi.org/10.1182/blood.V126.23.303.303
Published: 2015
Journal Articles

RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development

Xiaomei Yan, MD PhD, Yoshihiro Hayashi, MD PhD, Xinghui Zhao, PhD, Aili Chen, PhD, Yue Zhang, MD, Fuhong He, Yunzhu Dong, Yalan Rao, PhD, Bo Li, Rajeana Conway, Alba Maiques-Díaz, Nuomin Huang, Shannon E Elf, Johannes Zuber, MD, Zhijian Xiao, MD, William Tse, Daniel G. Tenen, MD, Qianfei Wang, Wei Chen, James C. Mulloy, PhD, Stephen D Nimer, MD, Gang Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 2187.
https://doi.org/10.1182/blood.V124.21.2187.2187
Published: 2014
Journal Articles

Novel Myelodysplastic Syndromes-like Mouse Models By Cooperating Genetic/Epigenetic Mutations Reveal the Critical Role of HIF-1α for Disease Development

Yoshihiro Hayashi, MD PhD, Yue Zhang, MD, Xiaomei Yan, MD PhD, Goro Sashida, MD PhD, Zefeng Xu, MD, Yunzhu Dong, Hironori Harada, MD PhD, Zhijian Xiao, MD, Gang Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 362.
https://doi.org/10.1182/blood.V124.21.362.362
Published: 2014
Journal Articles

Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal

Xinghui Zhao, Aili Chen, Xiaomei Yan, Yue Zhang, Fuhong He, Yoshihiro Hayashi, Yunzhu Dong, Yalan Rao, Bo Li, Rajeana M. Conway, Alba Maiques-Diaz, Shannon E. Elf, Nuomin Huang, Johannes Zuber, Zhijian Xiao, William Tse, Daniel G. Tenen, Qianfei Wang, Wei Chen, James C. Mulloy, Stephen D. Nimer, Gang Huang
Journal: Blood
Blood (2014) 123 (11): 1729–1738.
https://doi.org/10.1182/blood-2013-03-489575
Published: 2014
Includes: Supplemental data