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Journal Articles

Proteomic Profiling of HTLV-1 Carriers and ATL Patients Reveal TNFR2 As a Novel Diagnostic and Chemosensitivity Biomarker for ATL

Carmina Louise Hugo Guerrero, MS, Yoshiko Yamashita, PhD, Megumi Kuba-Miyara, PhD, Naoki Imaizumi, PhD, Shugo Sakihama, PhD, Masaki Hayashi, MD, Takashi Miyagi, MD PhD, Satoko Morishima, MD PhD, Kennosuke Karube, MD PhD, Yuetsu Tanaka, PhD, Hiroaki Masuzaki, MD PhD, Takuya Fukushima, MD PhD

Blood (2019) 134 (Supplement_1): 660.

https://doi.org/10.1182/blood-2019-129817

Published: 2019

Journal Articles

Novel Cellular Immunotherapy Using Allogeneic Vγ9/δ2-T Cells Gene-Modified to Express HTLV-1 P40Tax-Specific TCR for the Treatment of Adult T Cell Leukemia

Hiroshi Fujiwara, MD PhD, Satoshi Okumura, Yoshihiro Miyahara, Linan Wan, Isao Tawara, MD PhD, Tatsuro Jo, MD PhD, Yuetsu Tanaka, PhD, Yoshimasa Tanaka, PhD, Hiroaki Ikeda, Hiroshi Shiku

Blood (2019) 134 (Supplement_1): 3216.

https://doi.org/10.1182/blood-2019-122412

Published: 2019

Journal Articles

Cyclin-dependent kinase 9 is a novel specific molecular target in adult T-cell leukemia/lymphoma

Blood (2017) 130 (9): 1114–1124.

https://doi.org/10.1182/blood-2016-09-741983

Published: 2017

Includes: Supplemental data

Journal Articles

Polycomb-dependent epigenetic landscape in adult T-cell leukemia

Dai Fujikawa, Shota Nakagawa, Makoto Hori, Naoya Kurokawa, Ai Soejima, Kazumi Nakano, Tadanori Yamochi, Makoto Nakashima, Seiichiro Kobayashi, Yuetsu Tanaka, Masako Iwanaga, Atae Utsunomiya, Kaoru Uchimaru, Makoto Yamagishi, Toshiki Watanabe

Blood (2016) 127 (14): 1790–1802.

https://doi.org/10.1182/blood-2015-08-662593

Published: 2016

Includes: Supplemental data

Journal Articles

Polycomb-Dependent Epigenetic Landscape in Adult T Cell Leukemia (ATL); Providing Proof of Concept for Targeting EZH1/2 to Selectively Eliminate the HTLV-1 Infected Population

Makoto Yamagishi, PhD, Dai Fujikawa, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Shota Nakagawa, Makoto Hori, Naoya Kurokawa, Ai Soejima, Kazumi Nakano, PhD, Tadanori Yamochi, PhD, Makoto Nakashima, Seiichiro Kobayashi, MD, PhD, Yuetsu Tanaka, MD, PhD, Masako Iwanaga, MD, PhD, Atae Utsunomiya, MD, PhD, Kaoru Uchimaru, MD, PhD, Kunihiro Tsukasaki, MD, PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD

Blood (2015) 126 (23): 572.

https://doi.org/10.1182/blood.V126.23.572.572

Published: 2015

Journal Articles

HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with USP10

Masahiko Takahashi, Masaya Higuchi, Grace Naswa Makokha, Hideaki Matsuki, Manami Yoshita, Yuetsu Tanaka, Masahiro Fujii

Blood (2013) 122 (5): 715–725.

https://doi.org/10.1182/blood-2013-03-493718

Published: 2013

Includes: Supplemental data

Journal Articles

Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes

Gildas Belrose, Antoine Gross, Stéphane Olindo, Agnès Lézin, Maryvonne Dueymes, Isabelle Komla-Soukha, Didier Smadja, Yuetsu Tanaka, Luc Willems, Jean-Michel Mesnard, Jean-Marie Peloponese, Jr, Raymond Césaire

Blood (2011) 118 (9): 2483–2491.

https://doi.org/10.1182/blood-2010-11-321364

Published: 2011

Journal Articles

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs

Francesca Rende, Ilaria Cavallari, Alberto Corradin, Micol Silic-Benussi, Frederic Toulza, Gianna M. Toffolo, Yuetsu Tanaka, Steven Jacobson, Graham P. Taylor, Donna M. D'Agostino, Charles R. M. Bangham, Vincenzo Ciminale

Blood (2011) 117 (18): 4855–4859.

https://doi.org/10.1182/blood-2010-11-316463

Published: 2011

Includes: Supplemental data

Journal Articles

Inhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I–associated neurologic disease

Unsong Oh, Matthew J. McCormick, Dibyadeep Datta, Richard V. Turner, Kathryn Bobb, Dileep D. Monie, D. Robert Sliskovic, Yuetsu Tanaka, Jie Zhang, Jeffrey Meshulam, Steven Jacobson

Blood (2011) 117 (12): 3363–3369.

https://doi.org/10.1182/blood-2010-10-306571

Published: 2011

Journal Articles

Overexpression of caveolin-1 in adult T-cell leukemia

Shigeki Sawada, Chie Ishikawa, Hiroe Tanji, Sawako Nakachi, Masachika Senba, Taeko Okudaira, Jun-Nosuke Uchihara, Naoya Taira, Kazuiku Ohshiro, Yasuaki Yamada, Yuetsu Tanaka, Hiroshi Uezato, Koichi Ohshima, Ken Sasai, Boudewijn M. T. Burgering, Madeleine Duc Dodon, Masahiro Fujii, Hajime Sunakawa, Naoki Mori

Blood (2010) 115 (11): 2220–2230.

https://doi.org/10.1182/blood-2009-08-240044

Published: 2010

Journal Articles

HTLV-1–Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse

Mohamed Nejmeddine, Veera S. Negi, Sohini Mukherjee, Yuetsu Tanaka, Kim Orth, Graham P. Taylor, Charles R. M. Bangham

Blood (2009) 114 (5): 1016–1025.

https://doi.org/10.1182/blood-2008-03-136770

Published: 2009

Includes: Supplemental data

Journal Articles

High frequency of CD4 + FoxP3 + cells in HTLV-1 infection: inverse correlation with HTLV-1–specific CTL response

Frederic Toulza, Adrian Heaps, Yuetsu Tanaka, Graham P. Taylor, Charles R. M. Bangham

Blood (2008) 111 (10): 5047–5053.

https://doi.org/10.1182/blood-2007-10-118539

Published: 2008

Includes: Supplemental data

Journal Articles

Histone deacetylase inhibitors increase virus gene expression but decrease CD8 + cell antiviral function in HTLV-1 infection

Angelina Jane Mosley, Kiran N. Meekings, Corinna McCarthy, Dawn Shepherd, Vincenzo Cerundolo, Ralph Mazitschek, Yuetsu Tanaka, Graham P. Taylor, Charles R. Bangham

Blood (2006) 108 (12): 3801–3807.

https://doi.org/10.1182/blood-2006-03-013235

Published: 2006

Includes: Supplemental data

Journal Articles

Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1–infected lymphocytes

Amanda L. Barnard, Tadahiko Igakura, Yuetsu Tanaka, Graham P. Taylor, Charles R.M. Bangham

Blood (2005) 106 (3): 988–995.

https://doi.org/10.1182/blood-2004-07-2850

Published: 2005

Journal Articles

Low frequency of CD94/NKG2A + T lymphocytes in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers

Mineki Saito, Veronique M. Braud, Peter Goon, Emmanuel Hanon, Graham P. Taylor, Akiko Saito, Nobutaka Eiraku, Yuetsu Tanaka, Koichiro Usuku, Jonathan N. Weber, Mitsuhiro Osame, Charles R. M. Bangham

Blood (2003) 102 (2): 577–584.

https://doi.org/10.1182/blood-2002-09-2855

Published: 2003

Journal Articles

Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element

Nozomu Hiraiwa, Tomonori Yabuta, Keijiro Yoritomi, Miki Hiraiwa, Yuetsu Tanaka, Takeshi Suzuki, Mitsuaki Yoshida, Reiji Kannagi

Blood (2003) 101 (9): 3615–3621.

https://doi.org/10.1182/blood-2002-07-2301

Published: 2003

Journal Articles

Bay 11-7082 inhibits transcription factor NF-κB and induces apoptosis of HTLV-I–infected T-cell lines and primary adult T-cell leukemia cells

Naoki Mori, Yasuaki Yamada, Shuichi Ikeda, Yoshihiro Yamasaki, Kunihiro Tsukasaki, Yuetsu Tanaka, Masao Tomonaga, Naoki Yamamoto, Masahiro Fujii

Blood (2002) 100 (5): 1828–1834.

https://doi.org/10.1182/blood-2002-01-0151

Published: 2002

Journal Articles

High frequencies of Th1-type CD4 + T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis

Peter K. C. Goon, Emmanuel Hanon, Tadahiko Igakura, Yuetsu Tanaka, Jonathan N. Weber, Graham P. Taylor, Charles R. M. Bangham

Blood (2002) 99 (9): 3335–3341.

https://doi.org/10.1182/blood.V99.9.3335

Published: 2002

Journal Articles

High production of interferon γ but not interleukin-2 by human T-lymphotropic virus type I–infected peripheral blood mononuclear cells

Emmanuel Hanon, Peter Goon, Graham P. Taylor, Hitoshi Hasegawa, Yuetsu Tanaka, Jonathan N. Weber, Charles R. M. Bangham

Blood (2001) 98 (3): 721–726.

https://doi.org/10.1182/blood.V98.3.721

Published: 2001

Journal Articles

Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor β signaling through interaction with CREB-binding protein/p300

Naoki Mori, Mariko Morishita, Tomoo Tsukazaki, Chou-Zen Giam, Atsushi Kumatori, Yuetsu Tanaka, Naoki Yamamoto

Blood (2001) 97 (7): 2137–2144.

https://doi.org/10.1182/blood.V97.7.2137

Published: 2001

NARROW

Proteomic Profiling of HTLV-1 Carriers and ATL Patients Reveal TNFR2 As a Novel Diagnostic and Chemosensitivity Biomarker for ATL

Novel Cellular Immunotherapy Using Allogeneic Vγ9/δ2-T Cells Gene-Modified to Express HTLV-1 P40Tax-Specific TCR for the Treatment of Adult T Cell Leukemia

Cyclin-dependent kinase 9 is a novel specific molecular target in adult T-cell leukemia/lymphoma

Polycomb-dependent epigenetic landscape in adult T-cell leukemia

Polycomb-Dependent Epigenetic Landscape in Adult T Cell Leukemia (ATL); Providing Proof of Concept for Targeting EZH1/2 to Selectively Eliminate the HTLV-1 Infected Population

HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with USP10

Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs

Inhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I–associated neurologic disease

Overexpression of caveolin-1 in adult T-cell leukemia

HTLV-1–Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse

High frequency of CD4 + FoxP3 + cells in HTLV-1 infection: inverse correlation with HTLV-1–specific CTL response

Histone deacetylase inhibitors increase virus gene expression but decrease CD8 + cell antiviral function in HTLV-1 infection

Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1–infected lymphocytes

Low frequency of CD94/NKG2A + T lymphocytes in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers

Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element

Bay 11-7082 inhibits transcription factor NF-κB and induces apoptosis of HTLV-I–infected T-cell lines and primary adult T-cell leukemia cells

High frequencies of Th1-type CD4 + T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis

High production of interferon γ but not interleukin-2 by human T-lymphotropic virus type I–infected peripheral blood mononuclear cells

Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor β signaling through interaction with CREB-binding protein/p300

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American Society of Hematology

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American Society of Hematology

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