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Journal Articles

Regulation of Heterochromatin Landscape in T-Cell Acute Lymphoblastic Leukemia

Yali Ding, Bing He, Jonathon Payne, Dhimant Desai, Arati Sharma, Daniel Bogush, Elanora Dovat, Joseph Schramm, Melanie Ehudin, Diwakar Bastihalli Tukaramrao, Chandrika Gowda, Sinisa Dovat
Journal: Blood
Blood (2021) 138 (Supplement 1): 2217.
https://doi.org/10.1182/blood-2021-154388
Published: 2021
Journal Articles

IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia

Chunhua Song, Zheng Ge, Yali Ding, Bi-Hua Tan, Dhimant Desai, Krishne Gowda, Shantu Amin, Raghavendra Gowda, Gavin P. Robertson, Feng Yue, Suming Huang, Vladimir Spiegelman, Jonathon L. Payne, Mark E. Reeves, Zafer Gurel, Soumya Iyer, Pavan Kumar Dhanyamraju, Meixian Xiang, Yuka Imamura Kawasawa, Nathalia M. Cury, José Andrés Yunes, Mary McGrath, Joe Schramm, Ruijun Su, Yiping Yang, Zhijun Zhao, Xiaoguang Lyu, Markus Muschen, Kimberly J. Payne, Chandrika Gowda, Sinisa Dovat
Journal: Blood
Blood (2020) 136 (13): 1520–1534.
https://doi.org/10.1182/blood.2019002655
Published: 2020
Includes: Supplemental data
Journal Articles

CK2 Inhibitor CX4945 Shows Strong In Vivo Synergistic Anti-Leukemia Activity with Rapamycin in B-ALL Due to Enhanced Ikaros Mediated Repression of mTOR Pathway

Chandrika Gowda, MBBS, Chunhua Song, MD, Yali Ding, PhD, Pavan kumar Dhanyamraju, PhD, Soumya Iyer, PhD, Jonathon Payne, Yevgeniya Bamme, MD, Arati Sharma, PhD, Kimberly J. Payne, PhD, Sinisa Dovat, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2634.
https://doi.org/10.1182/blood-2019-131790
Published: 2019
Journal Articles

CK2 Inhibitor CX4945 Shows Strong In Vivo Anti Leukemia Effect in AML Via Augmented Ikaros-Mediated Regulation of Global Epigenetic Landscape

Chandrika Gowda, MBBS, Chunhua Song, MD, Sadie Steffens, PhD, Yali Ding, PhD, Bo Zhang, Feng Yue, PhD, Soumya Iyer, PhD, Pavan kumar Dhanyamraju, PhD, Jonathon Payne, Morgann Reed, BS, Kimberly J. Payne, PhD, Sinisa Dovat, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2522.
https://doi.org/10.1182/blood-2019-131200
Published: 2019
Journal Articles

Transcriptional Repression of the LMO2 Oncogene By Ikaros in T-Cell Acute Lymphoblastic Leukemia

Yali Ding, PhD, Chunhua Song, PhD, Chandrika S. Gowda, MD, Malika Kapadia, Kimberly Payne, PhD, Sinisa Dovat, MDPhD
Journal: Blood
Blood (2016) 128 (22): 439.
https://doi.org/10.1182/blood.V128.22.439.439
Published: 2016
Journal Articles

Targeting Casein Kinase II Exerts a Therapeutic Effect in Pediatric High Risk Leukemia Via Inhibition of Cell Cycle Progression and the PI3K Pathway

Chandrika S. Gowda, MD, Chunhua Song, PhD, Yali Ding, PhD, Sunil Muthusami, MD, Kimberly Payne, PhD, Zheng Ge, Sinisa Dovat, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4800.
https://doi.org/10.1182/blood.V126.23.4800.4800
Published: 2015
Journal Articles

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

Chunhua Song, Chandrika Gowda, Xiaokang Pan, Yali Ding, Yongqing Tong, Bi-Hua Tan, Haijun Wang, Sunil Muthusami, Zheng Ge, Mansi Sachdev, Shantu G. Amin, Dhimant Desai, Krishne Gowda, Raghavendra Gowda, Gavin P. Robertson, Hilde Schjerven, Markus Muschen, Kimberly J. Payne, Sinisa Dovat
Journal: Blood
Blood (2015) 126 (15): 1813–1822.
https://doi.org/10.1182/blood-2015-06-651505
Published: 2015
Includes: Supplemental data
Journal Articles

Restoring Ikaros Function in Leukemia : Casein Kinase II ( CK2) Inhibition Restores Ikaros Tumor Supressor Function and Shows Theraputic Efficacy in Preclinical Models of High Risk Pediatric Leukemia

Chandrika S. Gowda, MD, Chunhua Song, MD, PhD, Sunil Muthusami, MD, Yali Ding, PhD, Mansi Sachdev, MD, Kimberly Payne, PhD, Sinisa Dovat, MDPhD
Journal: Blood
Blood (2014) 124 (21): 3712.
https://doi.org/10.1182/blood.V124.21.3712.3712
Published: 2014
Journal Articles

Chromatin State Shaping the Gene Expression Profiling in the Inducible Differentiation of Promyelocytic Leukemia Cells

Chunhua Song, MD, PhD, Lisa Chung, PhD, Xiaokang Pan, Ph. D., Li Zhanjun, PhD, Yali Ding, PhD, Mansi Sachdev, MD, Sunil Muthusami, MD, Chandrika S. Gowda, MD, Zheng Ge, MD, PhD, Sadie Steffens, Bi-Hua Tan, MD, PhD, Christina Kendziorski, PhD, Michael Newton, PhD, Sinisa Dovat, MD,PhD
Journal: Blood
Blood (2014) 124 (21): 5188.
https://doi.org/10.1182/blood.V124.21.5188.5188
Published: 2014
Journal Articles

Epigenetic Control Of Cell Cycle-Promoting Genes By Ikaros and Casein Kinase II In B-Cell Acute Lymphoblastic Leukemia

Sinisa Dovat, MD, PhD, Chunhua Song, M.D., Ph.D, Xiaokang Pan, Ph. D., Yali Ding, Ph. D., Chandrika S. Gowda, MD, Marie S Bulathsinghala, Mansi Sachdev, M.D., Haijun Wang, Kimberly J Payne, PhD
Journal: Blood
Blood (2013) 122 (21): 3734.
https://doi.org/10.1182/blood.V122.21.3734.3734
Published: 2013