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Journal Articles

Perforin Is Important For Both CD4+ and CD8+ T Cell-Mediated Graft-Versus-Tumor Effect But Plays Differential Roles In CD4+ and CD8+ T Cell Expansion After Allogeneic Transplantation

Nicholas Leigh, Guanglin Bian, PhD, Wei Du, George L. Chen, MD, Hong Liu, MD, PhD, Philip L. McCarthy, Jr., MD, Xuefang Cao, PhD
Journal: Blood
Blood (2013) 122 (21): 3255.
https://doi.org/10.1182/blood.V122.21.3255.3255
Published: 2013
Journal Articles

Housing Mice At Sub-Thermoneutral Temperatures Influences Severity Of Gvhd In Mouse Models

Kathleen M Kokolus, MS, Nicholas D Leigh, BS, George Chen, MD, Philip L. McCarthy, Jr., MD, Xuefang Cao, PhD, Elizabeth A Repasky, PhD
Journal: Blood
Blood (2013) 122 (21): 5422.
https://doi.org/10.1182/blood.V122.21.5422.5422
Published: 2013
Journal Articles

Granzyme B is not required for regulatory T cell–mediated suppression of graft-versus-host disease

Sheng F. Cai, Xuefang Cao, Anjum Hassan, Todd A. Fehniger, Timothy J. Ley
Journal: Blood
Blood (2010) 115 (9): 1669–1677.
https://doi.org/10.1182/blood-2009-07-233676
Published: 2010
Includes: Supplemental data
Journal Articles

IL-12 Enhances Tumor Immunity Via Differential Effects On Regulatory T Cells and Cytotoxic Lymphocytes.

Xuefang Cao, PhD, Karen Leonard, BS
Journal: Blood
Blood (2009) 114 (22): 1656.
https://doi.org/10.1182/blood.V114.22.1656.1656
Published: 2009
Journal Articles

IL-12 Stimulates Interferon-Gamma Mediated Inhibition of Tumor-Induced Regulatory T Cell Proliferation and Enhances Tumor Clearance

Xuefang Cao, PhD, Lynne I. Collins, Sheng F. Cai, Joshua C. Mayer, Michael J. Walter, MD, David Piwnica-Worms, MD, PhD, Robert D. Schreiber, PhD, Timothy J. Ley, MD
Journal: Blood
Blood (2008) 112 (11): 2558.
https://doi.org/10.1182/blood.V112.11.2558.2558
Published: 2008
Journal Articles

Differential Regulation of Granzyme B and C Expression in Murine Cytotoxic T and NK Cells.

Sheng F. Cai, BS, Todd A. Fehniger, MD/PhD, Xuezhi Dai, PhD, Xuefang Cao, PhD, Timothy J. Ley, MD
Journal: Blood
Blood (2007) 110 (11): 2291.
https://doi.org/10.1182/blood.V110.11.2291.2291
Published: 2007
Journal Articles

Granzyme B Is Important for Treg-Mediated Suppression of NK-Dependent Tumor Clearance In Vivo .

Xuefang Cao, PhD, Sheng F. Cai, BS, Todd A. Fehniger, MD/PhD, Jiling Song, BS, David Piwnica-Worms, MD/PhD, Timothy James Ley, MD
Journal: Blood
Blood (2006) 108 (11): 133.
https://doi.org/10.1182/blood.V108.11.133.133
Published: 2006
Journal Articles

Murine NK Cells Require Activation-Dependent Expression of Granzyme B and Perforin To Become Potent Cytotoxic Effectors.

Todd A. Fehniger, MD, PhD, Sheng F. Cai, BS, Xuefang Cao, PhD, Andrew J. Bredemeyer, BS, Rachel M. Presti, MD/PhD, Anthony R. French, MD/PhD, Timothy James Ley, MD
Journal: Blood
Blood (2006) 108 (11): 920.
https://doi.org/10.1182/blood.V108.11.920.920
Published: 2006
Journal Articles

Orphan Granzymes Downstream from Granzyme B Are Important for Tumor Clearance In Vivo and in Vitro .

Xuefang Cao, PhD, Paula A. Revell, PhD, William J. Grossman, MD, PhD, Dori A. Thomas, PhD, Zhi Hong Lu, PhD, Timothy J. Ley, MD
Journal: Blood
Blood (2004) 104 (11): 2653.
https://doi.org/10.1182/blood.V104.11.2653.2653
Published: 2004
Journal Articles

Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax

Xuefang Cao, Xingming Deng, W. Stratford May
Journal: Blood
Blood (2003) 102 (7): 2605–2614.
https://doi.org/10.1182/blood-2003-01-0211
Published: 2003