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Journal Articles

Small Molecule Bda-366 As a Bcl2-BH4 Antagonist for Multiple Myeloma Therapy

Jiusheng Deng, PhD, Dongkyoo Park, PhD, Mengchang Wang, Qiaoya Deng, Shannon Matulis, PhD, Lawrence H. Boise, PhD, Xingming Deng, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2049.
https://doi.org/10.1182/blood.V126.23.2049.2049
Published: 2015
Journal Articles

Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding

Xingming Deng, Fengqin Gao, W. Stratford May
Journal: Blood
Blood (2009) 113 (2): 422–428.
https://doi.org/10.1182/blood-2008-06-165134
Published: 2009
Journal Articles

Protein Phosphatase 2A Inactivates Bcl2’s Antiapoptotic Function by Dephosphorylation and Up-Regulation of Bcl2-p53 Binding.

Xingming Deng, MD, Fengqin Gao, Tammy Flagg, W. Stratford May, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 1436.
https://doi.org/10.1182/blood.V108.11.1436.1436
Published: 2006
Journal Articles

Bcl2 Flexible Loop Domain Positively and Negatively Regulates Survival Function through Direct Interaction with p53.

Xingming Deng, MD, Fengqin Gao, Tammy Flagg, Jessica Anderson, W. Stratford May, MD, Ph.D
Journal: Blood
Blood (2005) 106 (11): 2623.
https://doi.org/10.1182/blood.V106.11.2623.2623
Published: 2005
Journal Articles

Mechanisms of Apoptosis Induction by BH3 Inhibitor ABT-737 in AML.

Michael Andreeff, MD, PhD, Rooha Contractor, Peter P. Ruvolo, PhD, Xingming Deng, MD, PhD, Ismael Samudio, PhD, Yue-Xi Shi, Teresa McQueen, BS, Rui-Yu Wang, MD, PhD, Wendy Schober, Xiaoyang Ling, PhD, Frank C. Marini, PhD, David Harris, Zeev Estrov, MD, James McCubrey, PhD, W. Stratford May, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 244.
https://doi.org/10.1182/blood.V106.11.244.244
Published: 2005
Journal Articles

Inhibition of Bcl-2 Signaling at Nanomolar Concentrations by Small Molecule BH3 Inhibitor, ABT-737 as a Novel Therapeutic Strategy in Acute Myeloid Leukemia (AML).

Rooha Contractor, Marina Konopleva, M.D., Ph.D., Xingming Deng, M.D., Ph.D., David Harris, Peter Ruvolo, Ph.D., Zeev Estrov, M.D., W. Stratford May, M.D., Ph.D., Saul H. Rosenberg, Ph.D., Michael Andreeff, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 760.
https://doi.org/10.1182/blood.V104.11.760.760
Published: 2004
Journal Articles

Bcl2 retards G1/S cell cycle transition by regulating intracellular ROS

Xingming Deng, Fengqin Gao, W. Stratford May, Jr.
Journal: Blood
Blood (2003) 102 (9): 3179–3185.
https://doi.org/10.1182/blood-2003-04-1027
Published: 2003
Journal Articles

Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax

Xuefang Cao, Xingming Deng, W. Stratford May
Journal: Blood
Blood (2003) 102 (7): 2605–2614.
https://doi.org/10.1182/blood-2003-01-0211
Published: 2003