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Journal Articles

DNMT3A Mutations Enhance T-ALL Survival, Which Is Reversed By JAK/STAT Inhibition

Wangisa M.B. Dunuwille, William Casey Wilson, Nancy Issa, Won Kyun Koh, Wentao Han, Grant A Challen
Journal: Blood
Blood (2022) 140 (Supplement 1): 8756–8757.
https://doi.org/10.1182/blood-2022-167136
Published: 2022
Journal Articles

The Histone Demethylase KDM6B Is a Genetic Dependency of NOTCH1-Driven T-ALL

Nancy Issa, Hamza Celik, Hassan Bjeije, Wangisa M.B. Dunuwille, Won Kyun Koh, Tyler Parsons, Christine R Zhang, Wentao Han, Grant A. Challen
Journal: Blood
Blood (2021) 138 (Supplement 1): 782.
https://doi.org/10.1182/blood-2021-150790
Published: 2021
Journal Articles

DNMT3A Regulates Hematopoietic Stem Cell Function Via DNA Methylation-Independent Functions

Won Kyun Koh, Hamza Celik, Jacob Tao, Jake Fairchild, Ostap Kukhar, Christine R Zhang, Paul Gontarz, Grant A. Challen
Journal: Blood
Blood (2021) 138 (Supplement 1): 24.
https://doi.org/10.1182/blood-2021-153759
Published: 2021
Journal Articles

Txnip enhances Fitness of Dnmt3a -Mutant Hematopoietic Stem Cells Via p21

Christine R Zhang, Elizabeth Leigh Ostrander, Jiameng Sun, Cates Mallaney, Hamza Celik, Won Kyun Koh, Katherine Y. King, Paul Gontarz, Grant A. Challen
Journal: Blood
Blood (2021) 138 (Supplement 1): 600.
https://doi.org/10.1182/blood-2021-146667
Published: 2021
Journal Articles

A Novel Humanized Animal Model Reveals Clonal Architecture and Therapeutic Vulnerabilities in Myelofibrosis

Hamza Celik, PhD, Ethan Krug, Hassan Bjeije, PhD, Nancy Issa, MD, Wentao Han, Won Kyun Koh, Ruochao CZ Zhang, PhD, Maggie J. Allen, Terrence N Wong, MD PhD, Daniel AC Fisher, PhD, Tiandao Li, Stephen T. Oh, MD PhD, Grant A. Challen, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-143034
Published: 2020
Journal Articles

Jarid2 Restricts Long-Term Repopulating Stem Cell Capacity in Multipotent Progenitors and Acts As Tumor Suppressor in Chronic Myeloid Neoplasms

Hamza Celik, PhD, Won Kyun Koh, MS, Elizabeth Leigh Ostrander, BS, Ashley C. Kramer, BS, William C Wilson, PhD, Greg Fishberger, BS, Cates Mallaney, MS, BS, Alok Kothari, MD, Grant Anthony Challen, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 488.
https://doi.org/10.1182/blood.V130.Suppl_1.488.488
Published: 2017