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Winifred Keeble
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Journal Articles

Alda-1 Constrains TLR-Induced Cytokine Overproduction By Fanconi Anemia Macrophages By Enhancing ALDH1A1 Activity

Michael Garbati, PhD BS, Winifred Keeble, BS, Wenjin Yang, PhD, Grover C. Bagby, Jr., MD MACP
Journal: Blood
Blood (2015) 126 (23): 1000.
https://doi.org/10.1182/blood.V126.23.1000.1000
Published: 2015
Journal Articles

Placental Growth Factor Enhances Toll-like Receptor-Induced Inflammatory Cytokine Gene Expression Transcriptionally in Human Mononuclear Phagocytes

Laura F Newell, MD, Shernan G. Holtan, MD, Jason Rosenzweig, PhD, Jane Yates, Michael Garbati, PhD BS, R. K. Rathbun, Winifred Keeble, BS, Jeffrey W. Tyner, PhD, Irina Burd, MD PhD, Grover C. Bagby, MD
Journal: Blood
Blood (2015) 126 (23): 1006.
https://doi.org/10.1182/blood.V126.23.1006.1006
Published: 2015
Journal Articles

FANCA and FANCC modulate TLR and p38 MAPK–dependent expression of IL-1β in macrophages

Michael R. Garbati, Laura E. Hays, Winifred Keeble, Jane E. Yates, R. Keaney Rathbun, Grover C. Bagby
Journal: Blood
Blood (2013) 122 (18): 3197–3205.
https://doi.org/10.1182/blood-2013-02-484816
Published: 2013
Includes: Supplemental data
Journal Articles

p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes

Praveen Anur, Jane Yates, Michael R. Garbati, Scott Vanderwerf, Winifred Keeble, Keaney Rathbun, Laura E. Hays, Jeffrey W. Tyner, Johanna Svahn, Enrico Cappelli, Carlo Dufour, Grover C. Bagby
Journal: Blood
Blood (2012) 119 (9): 1992–2002.
https://doi.org/10.1182/blood-2011-06-354647
Published: 2012
Journal Articles

TLR8-dependent TNF-α overexpression in Fanconi anemia group C cells

Scott M. Vanderwerf, Johanna Svahn, Susan Olson, R. Keaney Rathbun, Christina Harrington, Jane Yates, Winifred Keeble, David C. Anderson, Praveen Anur, Noemi F. Pereira, Daniela V. Pilonetto, Ricardo Pasquini, Grover C. Bagby
Journal: Blood
Blood (2009) 114 (26): 5290–5298.
https://doi.org/10.1182/blood-2009-05-222414
Published: 2009
Includes: Supplemental data
Journal Articles

A High Throughput Small Molecule Screening Method for Fanconi Anemia.

Anur Praveen, MD, Jeffrey W Tyner, PhD, Scott Vanderwerff, Ph.D, Winifred Keeble, Grover C. Bagby, Jr., MD
Journal: Blood
Blood (2009) 114 (22): 3191.
https://doi.org/10.1182/blood.V114.22.3191.3191
Published: 2009
Journal Articles

Oxidative Stress Induces Binding of FANCD2 to STAT5 and Facilitates STAT5-Dependent Survival Signals.

Grover Bagby, MD, Winifred Keeble, MS, Tara Koretsky, Dylan Zodrow, Richard Jove, PhD, Laura Hays, PhD, Hanqian Carlson, PhD
Journal: Blood
Blood (2004) 104 (11): 33.
https://doi.org/10.1182/blood.V104.11.33.33
Published: 2004
Journal Articles

The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality

Qishen Pang, Tracy A. Christianson, Winifred Keeble, Jane Diaz, Gregory R. Faulkner, Carol Reifsteck, Susan Olson, Grover C. Bagby
Journal: Blood
Blood (2001) 98 (5): 1392–1401.
https://doi.org/10.1182/blood.V98.5.1392
Published: 2001
Journal Articles

Functional correction of FA-C cells with FANCC suppresses the expression of interferon γ–inducible genes

Sara R. Fagerlie, Jane Diaz, Tracy A. Christianson, Kelli McCartan, Winifred Keeble, Gregory R. Faulkner, Grover C. Bagby
Journal: Blood
Blood (2001) 97 (10): 3017–3024.
https://doi.org/10.1182/blood.V97.10.3017
Published: 2001
Journal Articles

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon γ, tumor necrosis factor-α, and double-stranded RNA

Qishen Pang, Winifred Keeble, Jane Diaz, Tracy A. Christianson, Sara Fagerlie, Keaney Rathbun, Gregory R. Faulkner, Michael O'Dwyer, Grover C. Bagby, Jr
Journal: Blood
Blood (2001) 97 (6): 1644–1652.
https://doi.org/10.1182/blood.V97.6.1644
Published: 2001
Journal Articles

Interferon-γ–induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8–dependent activation of caspase 3 family members

R. Keaney Rathbun, Tracy A. Christianson, Gregory R. Faulkner, Gary Jones, Winifred Keeble, Michael O'Dwyer, Grover C. Bagby
Journal: Blood
Blood (2000) 96 (13): 4204–4211.
https://doi.org/10.1182/blood.V96.13.4204
Published: 2000
Journal Articles

Inactivation of the Fanconi Anemia Group C Gene Augments Interferon-γ–Induced Apoptotic Responses in Hematopoietic Cells

R. Keaney Rathbun, Gregory R. Faulkner, Marika H. Ostroski, Tracy A. Christianson, Grant Hughes, Gary Jones, Robert Cahn, Richard Maziarz, Gordon Royle, Winifred Keeble, Michael C. Heinrich, Markus Grompe, Paula A. Tower, Grover C. Bagby
Journal: Blood
Blood (1997) 90 (3): 974–985.
https://doi.org/10.1182/blood.V90.3.974
Published: 1997