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William G. Kaelin, Jr
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Journal Articles

Transformation by Mutant IDH and ( R )-2HG Is Reversible.

Julie-Aurore Losman, MD, PhD, Ryan E. Looper, PhD, William G. Kaelin, Jr., MD
Journal: Blood
Blood (2012) 120 (21): 2413.
https://doi.org/10.1182/blood.V120.21.2413.2413
Published: 2012
Journal Articles

Mutation Selective IDH Inhibitors Mediate Histone and DNA Methylation Changes

Katharine Yen, Fang Wang, Stefanie Schalm, Erica Hansen, Kimberly Straley, BS, Andrew Kernytsky, Sung Choe, Wei Liu, Janeta Popovici-Muller, Jeremy Travins, Hua Yang, Lee Silverman, Julie Losman Aurore, William G. Kaelin, Jr., MD, Stefan Gross, Lenny Dang, Frank Salituro, Jeffrey Saunders, Marion Dorsch, Samuel Agresta, MD, David P. Schenkein, MD, Michael Su, Scott Biller
Journal: Blood
Blood (2012) 120 (21): 3509.
https://doi.org/10.1182/blood.V120.21.3509.3509
Published: 2012
Journal Articles

Treatment of erythropoietin deficiency in mice with systemically administered siRNA

William Querbes, Roman L. Bogorad, Javid Moslehi, Jamie Wong, Amy Y. Chan, Elena Bulgakova, Satya Kuchimanchi, Akin Akinc, Kevin Fitzgerald, Victor Koteliansky, William G. Kaelin, Jr
Journal: Blood
Blood (2012) 120 (9): 1916–1922.
https://doi.org/10.1182/blood-2012-04-423715
Published: 2012
Includes: Supplemental data
Journal Articles

Enantiomer-Specific Transformation by 2HG Is Linked to Opposing Effects on α-Ketoglutarate-Dependent Dioxygenases

Julie-Aurore Losman, MD, PhD, Sungwoo Lee, PhD, Peppi Koivunen, MD, PhD, Ryan E. Looper, PhD, William G. Kaelin, Jr., MD
Journal: Blood
Blood (2011) 118 (21): LBA-4.
https://doi.org/10.1182/blood.V118.21.LBA-4.LBA-4
Published: 2011
Journal Articles

Liver Specific Delivery of siRNA Targeting EGLN Prolyl Hydroxylases Activates Hepatic Erythropoietin Production and Stimulates Erythropoiesis,

William Querbes, PhD, Roman Bogorad, PhD, Javid Moslehi, MD, Akin Akinc, PhD, Jamie Wong, PhD, Chris Zurenko, June Qin, Julia Hettinger, Satya Kuchimanchi, PhD, Klaus Charisse, PhD, Dinah WY Sah, PhD, Kevin Fitzgerald, PhD, Victor Kotelianski, MD, PhD, William G. Kaelin, Jr., MD
Journal: Blood
Blood (2011) 118 (21): 3161.
https://doi.org/10.1182/blood.V118.21.3161.3161
Published: 2011
Journal Articles

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

Yoji Andrew Minamishima, Javid Moslehi, Nabeel Bardeesy, Darragh Cullen, Roderick T. Bronson, William G. Kaelin, Jr
Journal: Blood
Blood (2008) 111 (6): 3236–3244.
https://doi.org/10.1182/blood-2007-10-117812
Published: 2008
Includes: Supplemental data