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Journal Articles

A key role for platelet GPVI in neutrophil recruitment, migration, and NETosis in the early stages of acute lung injury

Philipp Burkard, Charlotte Schonhart, Timo Vögtle, David Köhler, Linyan Tang, Denise Johnson, Katherina Hemmen, Katrin G. Heinze, Alexander Zarbock, Heike M. Hermanns, Peter Rosenberger, Bernhard Nieswandt
Journal: Blood
Blood (2023) 142 (17): 1463–1477.
https://doi.org/10.1182/blood.2023019940
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Zoltan Nagy, Timo Vögtle, Mitchell J. Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G. Neel, Guillaume E. Desanti, Alexandra Mazharian, Yotis A. Senis
Journal: Blood
Blood (2019) 133 (4): 331–343.
https://doi.org/10.1182/blood-2018-09-877787
Published: 2019
Includes: Supplemental data
Journal Articles

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

Mitchell J. Geer, Johanna P. van Geffen, Piraveen Gopalasingam, Timo Vögtle, Christopher W. Smith, Silke Heising, Marijke J. E. Kuijpers, Bibian M. E. Tullemans, Gavin E. Jarvis, Johannes A. Eble, Mark Jeeves, Michael Overduin, Johan W. M. Heemskerk, Alexandra Mazharian, Yotis A. Senis
Journal: Blood
Blood (2018) 132 (13): 1413–1425.
https://doi.org/10.1182/blood-2017-10-802975
Published: 2018
Includes: Supplemental data
Journal Articles

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

Inga Hofmann, Mitchell J. Geer, Timo Vögtle, Andrew Crispin, Dean R. Campagna, Alastair Barr, Monica L. Calicchio, Silke Heising, Johanna P. van Geffen, Marijke J. E. Kuijpers, Johan W. M. Heemskerk, Johannes A. Eble, Klaus Schmitz-Abe, Esther A. Obeng, Michael Douglas, Kathleen Freson, Corinne Pondarré, Rémi Favier, Gavin E. Jarvis, Kyriacos Markianos, Ernest Turro, Willem H. Ouwehand, Alexandra Mazharian, Mark D. Fleming, Yotis A. Senis
Journal: Blood
Blood (2018) 132 (13): 1399–1412.
https://doi.org/10.1182/blood-2017-08-802769
Published: 2018
Includes: Supplemental data
Journal Articles

Twinfilin 2a regulates platelet reactivity and turnover in mice

Simon Stritt, Sarah Beck, Isabelle C. Becker, Timo Vögtle, Markku Hakala, Katrin G. Heinze, Xiaoping Du, Markus Bender, Attila Braun, Pekka Lappalainen, Bernhard Nieswandt
Journal: Blood
Blood (2017) 130 (15): 1746–1756.
https://doi.org/10.1182/blood-2017-02-770768
Published: 2017
Includes: Multimedia, Supplemental data
Journal Articles

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

Viola Lorenz, David Stegner, Simon Stritt, Timo Vögtle, Friedemann Kiefer, Walter Witke, Jürgen Schymeinsky, Steve P. Watson, Barbara Walzog, Bernhard Nieswandt
Journal: Blood
Blood (2015) 125 (26): 4069–4077.
https://doi.org/10.1182/blood-2014-11-611905
Published: 2015
Includes: Supplemental data
Journal Articles

Rap1-GTP–interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice

Brief Report
Simon Stritt, Karen Wolf, Viola Lorenz, Timo Vögtle, Shuchi Gupta, Michael R. Bösl, Bernhard Nieswandt
Journal: Blood
Blood (2015) 125 (2): 219–222.
https://doi.org/10.1182/blood-2014-08-597542
Published: 2015
Includes: Supplemental data
Journal Articles

Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice

Martina Morowski, Timo Vögtle, Peter Kraft, Christoph Kleinschnitz, Guido Stoll, Bernhard Nieswandt
Journal: Blood
Blood (2013) 121 (24): 4938–4947.
https://doi.org/10.1182/blood-2012-10-461459
Published: 2013
Includes: Supplemental data
Journal Articles

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

Frauke May, Ina Hagedorn, Irina Pleines, Markus Bender, Timo Vögtle, Johannes Eble, Margitta Elvers, Bernhard Nieswandt
Journal: Blood
Blood (2009) 114 (16): 3464–3472.
https://doi.org/10.1182/blood-2009-05-222273
Published: 2009
Includes: Multimedia, Supplemental data
Journal Articles

STIM1 is essential for Fcγ receptor activation and autoimmune inflammation

Attila Braun, J. Engelbert Gessner, David Varga-Szabo, Shahzad N. Syed, Stephanie Konrad, David Stegner, Timo Vögtle, Reinhold E. Schmidt, Bernhard Nieswandt
Journal: Blood
Blood (2009) 113 (5): 1097–1104.
https://doi.org/10.1182/blood-2008-05-158477
Published: 2009
Includes: Supplemental data