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Journal Articles

Loss of Alpha Globin Genes in Human Subjects Is Associated with Improved Nitric Oxide-Mediated Vascular Perfusion

Christopher C Denton, MD, Payal Shah, MS, Silvie Suriany, MS, Honglei Liu, MS, Wanwara Thuptimdang, MS, John Sunwoo, PhD, Patjanaporn Chalacheva, PhD, Saranya Veluswamy, MD, Roberta Miyeko Kato, MD, John C Wood, MD PhD, Jon A Detterich, MD, Michael C.K. Khoo, PhD, Thomas D. Coates, MD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-136745

Published: 2020

Journal Articles

Sustained Reductions in Red Blood Cell (RBC) Transfusion Burden and Events in β-Thalassemia with Luspatercept: Longitudinal Results of the Believe Trial

Ali T. Taher, Vip Viprakasit, Olivier Hermine, John B. Porter, MA, MD, FRCP, FRCPath, Antonio Piga, MD, Kevin H.M. Kuo, MDMSc,FRCPC, Thomas D. Coates, MD, Ersi Voskaridou, Abderrahim Khelif, Antonis Kattamis, Jeevan K. Shetty, George Zhang, Yu (Olivia) Tian, Dimana Miteva, Tatiana Zinger, Derek Tang, Jay T. Backstrom, Maria Domenica Cappellini

Blood (2020) 136 (Supplement 1): 45–46.

https://doi.org/10.1182/blood-2020-140310

Published: 2020

Journal Articles

Longitudinal Effect of Luspatercept Treatment on Iron Overload and Iron Chelation Therapy (ICT) in Adult Patients (Pts) with β-Thalassemia in the Believe Trial

Olivier Hermine, Maria Domenica Cappellini, Ali T. Taher, Thomas D. Coates, MD, Vip Viprakasit, Ersi Voskaridou, Ashutosh Lal, MD, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Jeevan K. Shetty, George Zhang, Yu (Olivia) Tian, Dimana Miteva, Tatiana Zinger, Derek Tang, Jay T. Backstrom, John B. Porter, MA, MD, FRCP, FRCPath

Blood (2020) 136 (Supplement 1): 47–48.

https://doi.org/10.1182/blood-2020-136517

Published: 2020

Journal Articles

Middle Cerebral Artery Velocities Are Inversely Related to Hemoglobin Levels and Acutely Drop in Response to RBC Transfusion: Implications for Stroke Screening in SCD

Ajay Perumbeti, MD, Obdulio Carreras, BS, Jon A Detterich, MD, Payal Shah, MS, John Sunwoo, MS, Michael Khoo, PhD, John C Wood, MD PhD, Thomas D. Coates, MD

Blood (2018) 132 (Supplement 1): 2374.

https://doi.org/10.1182/blood-2018-99-115485

Published: 2018

Journal Articles

Hemolysis and Tricuspid Regurgitation Jet Velocity Predict Mortality in Patients with Sickle Cell Disease

Payal Shah, MS, Adam Bush, PhD, Silvie Suriany, MS, Honglei Liu, MS, Henry J Forman, PhD, Patjanaporn Chalacheva, PhD, Wanwara Thuptimdang, MS, John Sunwoo, MS, Saranya Veluswamy, MD, Christopher Clement Denton, MD, Maha Khaleel, MD, Roberta Miyeko Kato, MD, Ajay Perumbeti, MD, Richard Sposto, PhD, Michael Khoo, PhD, Thomas D. Coates, MD, John C Wood, MD PhD, Jon A Detterich, MD

Blood (2018) 132 (Supplement 1): 1086.

https://doi.org/10.1182/blood-2018-99-119587

Published: 2018

Journal Articles

Sickle Cell Subjects Have a Stronger and Faster Neurally Mediated Vasoconstriction Response to Cold Pain That Correlates with Anxiety Scores

Saranya Veluswamy, MD, Payal Shah, MS, Maha Khaleel, MD, Mammen Puliyel, MD MBBS, Wanwara Thuptimdang, MS, Patjanaporn Chalacheva, PhD, John Sunwoo, MS, Christopher Clement Denton, MD, Roberta Miyeko Kato, MD, Jon A Detterich, MD, John C Wood, MD PhD, Richard Sposto, PhD, Michael Khoo, PhD, Lonnie Zeltzer, MD, Thomas D. Coates, MD

Blood (2018) 132 (Supplement 1): 854.

https://doi.org/10.1182/blood-2018-99-113655

Published: 2018

Journal Articles

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Blood (2018) 132 (Supplement 1): 163.

https://doi.org/10.1182/blood-2018-163

Published: 2018

Journal Articles

Cold Pain Causes the Greatest Drop in Microvascular Blood Flow in Sickle Cell Disease Subjects and Normal Controls Exposed to Graded Thermal Stimuli

Saranya Veluswamy, MD, Payal Shah, MS, Maha Khaleel, MD, Mammen Puliyel, MD, Wanwara Thuptimdang, MS, Patjanaporn Chalacheva, PhD, John Sunwoo, MS, Roberta Miyeko Kato, MD, Jon A Detterich, MD, John C Wood, MD PhD, Jennie Tsao, PhD, Lonnie Zeltzer, MD, Richard Sposto, PhD, Michael Khoo, PhD, Thomas D. Coates, MD

Blood (2017) 130 (Supplement 1): 4773.

https://doi.org/10.1182/blood.V130.Suppl_1.4773.4773

Published: 2017

Journal Articles

Blunted Cardiac Response to Head-up Tilt Occurs in Sickle Cell Disease but Not Healthy Controls

Patjanaporn Chalacheva, PhD, Roberta Miyeko Kato, MD, Payal Shah, MS, Saranya Veluswamy, MD, Jon A Detterich, MD, Thomas D. Coates, MD, Michael Khoo, PhD

Blood (2017) 130 (Supplement 1): 3538.

https://doi.org/10.1182/blood.V130.Suppl_1.3538.3538

Published: 2017

Journal Articles

Outcomes of Immunosuppressive Therapy for Pediatric Aplastic Anemia: A North American Pediatric Aplastic Anemia Consortium (NAPAAC) Study

Blood (2017) 130 (Supplement 1): 1168.

https://doi.org/10.1182/blood.V130.Suppl_1.1168.1168

Published: 2017

Journal Articles

Chronic Anemia Is Associated with Lower Cerebral and Peripheral Arterio-Venous Oxygen Gradients

Chau Vu, BS, Adam Bush, PhD, Soyoung Choi, BA, Xin Miao, BS, Thomas D. Coates, MD, John C Wood, MD PhD

Blood (2017) 130 (Supplement 1): 3542.

https://doi.org/10.1182/blood.V130.Suppl_1.3542.3542

Published: 2017

Journal Articles

Attention to Pain Modulates the Vasoconstriction Response to Thermal Pain in Sickle Cell Disease Subjects but Not in Controls

Saranya Veluswamy, MD, Payal Shah, MS, Patjanaporn Chalacheva, PhD, Maha Khaleel, MD, Mammen Puliyel, MD, Wanwara Thuptimdang, MS, Roberta Miyeko Kato, MD, John Sunwoo, MS, Jon A Detterich, MD, Jennie Tsao, PhD, Richard Sposto, PhD, John C Wood, MD PhD, Lonnie Zeltzer, MD, Michael Khoo, PhD, Thomas D. Coates, MD

Blood (2017) 130 (Supplement 1): 3523.

https://doi.org/10.1182/blood.V130.Suppl_1.3523.3523

Published: 2017

Journal Articles

Autonomic and Vascular Dysregulation Enhance Pain-Induced Peripheral Vasoconstriction in Sickle Cell Disease

Patjanaporn Chalacheva, PhD, Maha Khaleel, MD, John Sunwoo, MS, Jon A Detterich, MD, Payal Shah, MS, Roberta Miyeko Kato, MD, Wanwara Thuptimdang, MS, Herbert J Meiselman, ScD, Richard Sposto, PhD, Jennie Tsao, PhD, John C Wood, MD PhD, Lonnie Zeltzer, MD, Thomas D. Coates, MD, Michael C.K. Khoo, PhD

Blood (2016) 128 (22): 126.

https://doi.org/10.1182/blood.V128.22.126.126

Published: 2016

Journal Articles

Shear-Mediated Erythrocyte Nitric Oxide Production Is Differentially Regulated in Patients with Sickle Cell Disease

Jon A Detterich, MD, Iris Xu, BS, Silvie Suriany, MS, Derek Ponce, Adam M Bush, MS, John C Wood, MD PhD, Herbert J Meiselman, ScD, Henry Jay Forman, PhD, Thomas D. Coates, MD

Blood (2016) 128 (22): 1301.

https://doi.org/10.1182/blood.V128.22.1301.1301

Published: 2016

Journal Articles

Regional Susceptibility to Chronic Anemia in WM Microstructure Using Diffusion Tensor Imaging

Soyoung Choi, BA, Adam M Bush, MS, Matt Borzage, PhD, Anand Joshi, PhD, Thomas D. Coates, MD, Richard Leahy, PhD, John C Wood, MD PhD

Blood (2016) 128 (22): 3640.

https://doi.org/10.1182/blood.V128.22.3640.3640

Published: 2016

Journal Articles

Hemoglobin Level and Platelet Size Predicts Grey and White Matter Volume Loss Measured By Tensor Based Morphology in Sickle Cell Disease

Soyoung Choi, BA, Adam M Bush, MS, Matt Borzage, PhD, Anand Joshi, PhD, Thomas D. Coates, MD, Richard Leahy, PhD, John C Wood, MD PhD

Blood (2016) 128 (22): 2481.

https://doi.org/10.1182/blood.V128.22.2481.2481

Published: 2016

Journal Articles

Hemoglobin S Exhibits Distinct MRI Oximetry Calibration in Vitro

Adam M Bush, MS, Thomas D. Coates, MD, John C Wood, MD PhD

Blood (2016) 128 (22): 4842.

https://doi.org/10.1182/blood.V128.22.4842.4842

Published: 2016

Journal Articles

Peripheral Blood Flow Responses to Pain Following a Hypnosis Intervention in Sickle Cell Disease

Ravi Bhatt, B.S., Subhadra Evans, PhD, Lonnie Zeltzer, MD, Thomas D. Coates, MD, Jennie Tsao, PhD

Blood (2016) 128 (22): 4853.

https://doi.org/10.1182/blood.V128.22.4853.4853

Published: 2016

Journal Articles

Chronic Transfusion Therapy in Sickle Cell Disease - Effect on Macrovascular Function, Microvascular Function, and Tissue Oxygenation Decreases the Potential for Ischemia

Jon A Detterich, MD, Roberta Miyeko Kato, MD, Madushka Yohan DeZoysa, MD, Herbert J Meiselman, ScD, Thomas D. Coates, MD, John C Wood, MD PhD

Blood (2016) 128 (22): 3671.

https://doi.org/10.1182/blood.V128.22.3671.3671

Published: 2016

Journal Articles

Changes in Brain Oxygenation in Response to Inhaled 100% Oxygen Are Different in Sickle Cell Disease Patients

Shayan Farzad, BS, MS, Julie Coloigner, PhD, Adam M Bush, MS, Matt Borzage, PhD, Thomas D. Coates, MD, John C Wood, MD PhD

Blood (2016) 128 (22): 3667.

https://doi.org/10.1182/blood.V128.22.3667.3667

Published: 2016

NARROW

Loss of Alpha Globin Genes in Human Subjects Is Associated with Improved Nitric Oxide-Mediated Vascular Perfusion

Sustained Reductions in Red Blood Cell (RBC) Transfusion Burden and Events in β-Thalassemia with Luspatercept: Longitudinal Results of the Believe Trial

Longitudinal Effect of Luspatercept Treatment on Iron Overload and Iron Chelation Therapy (ICT) in Adult Patients (Pts) with β-Thalassemia in the Believe Trial

Middle Cerebral Artery Velocities Are Inversely Related to Hemoglobin Levels and Acutely Drop in Response to RBC Transfusion: Implications for Stroke Screening in SCD

Hemolysis and Tricuspid Regurgitation Jet Velocity Predict Mortality in Patients with Sickle Cell Disease

Sickle Cell Subjects Have a Stronger and Faster Neurally Mediated Vasoconstriction Response to Cold Pain That Correlates with Anxiety Scores

The Believe Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept in Adult Beta-Thalassemia Patients Who Require Regular Red Blood Cell (RBC) Transfusions

Cold Pain Causes the Greatest Drop in Microvascular Blood Flow in Sickle Cell Disease Subjects and Normal Controls Exposed to Graded Thermal Stimuli

Blunted Cardiac Response to Head-up Tilt Occurs in Sickle Cell Disease but Not Healthy Controls

Outcomes of Immunosuppressive Therapy for Pediatric Aplastic Anemia: A North American Pediatric Aplastic Anemia Consortium (NAPAAC) Study

Chronic Anemia Is Associated with Lower Cerebral and Peripheral Arterio-Venous Oxygen Gradients

Attention to Pain Modulates the Vasoconstriction Response to Thermal Pain in Sickle Cell Disease Subjects but Not in Controls

Autonomic and Vascular Dysregulation Enhance Pain-Induced Peripheral Vasoconstriction in Sickle Cell Disease

Shear-Mediated Erythrocyte Nitric Oxide Production Is Differentially Regulated in Patients with Sickle Cell Disease

Regional Susceptibility to Chronic Anemia in WM Microstructure Using Diffusion Tensor Imaging

Hemoglobin Level and Platelet Size Predicts Grey and White Matter Volume Loss Measured By Tensor Based Morphology in Sickle Cell Disease

Hemoglobin S Exhibits Distinct MRI Oximetry Calibration in Vitro

Peripheral Blood Flow Responses to Pain Following a Hypnosis Intervention in Sickle Cell Disease

Chronic Transfusion Therapy in Sickle Cell Disease - Effect on Macrovascular Function, Microvascular Function, and Tissue Oxygenation Decreases the Potential for Ischemia

Changes in Brain Oxygenation in Response to Inhaled 100% Oxygen Are Different in Sickle Cell Disease Patients

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American Society of Hematology

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ASH Publications

American Society of Hematology

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