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Journal Articles

Taking AIM

Thomas A. J. McKinnon

Blood (2024) 143 (19): 1887–1888.

https://doi.org/10.1182/blood.2024024034

Published: 2024

Journal Articles

2B or not 2B: art thou autoinhibitory?

Thomas A. J. McKinnon

Blood (2023) 141 (10): 1102–1103.

https://doi.org/10.1182/blood.2022019577

Published: 2023

Journal Articles

Getting under the skin: a new route for factor VIII?

Thomas A. J. McKinnon

Blood (2021) 137 (8): 1007–1008.

https://doi.org/10.1182/blood.2020008909

Published: 2021

Journal Articles

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

Jun Ishihara, Ako Ishihara, Richard D. Starke, Claire R. Peghaire, Koval E. Smith, Thomas A. J. McKinnon, Yoji Tabata, Koichi Sasaki, Michael J. V. White, Kazuto Fukunaga, Mike A. Laffan, Matthias P. Lutolf, Anna M. Randi, Jeffrey A. Hubbell

Blood (2019) 133 (24): 2559–2569.

https://doi.org/10.1182/blood.2019000510

Published: 2019

Journal Articles

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Alain Chion, Jamie M. O’Sullivan, Clive Drakeford, Gudmundur Bergsson, Niall Dalton, Sonia Aguila, Soracha Ward, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Lauren Brady, Orla Sheils, Michael Laffan, Thomas A. J. McKinnon, James S. O’Donnell

Blood (2016) 128 (15): 1959–1968.

https://doi.org/10.1182/blood-2016-04-709436

Published: 2016

Includes: Supplemental data

Journal Articles

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells

Richard D. Starke, Koralia E. Paschalaki, Clare E. F. Dyer, Kimberly J. Harrison-Lavoie, Jacqueline A. Cutler, Thomas A. J. McKinnon, Carolyn M. Millar, Daniel F. Cutler, Mike A. Laffan, Anna M. Randi

Blood (2013) 121 (14): 2773–2784.

https://doi.org/10.1182/blood-2012-06-435727

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S

Josefin Ahnström, Helena M. Andersson, Verity Hockey, Yiran Meng, Thomas A. J. McKinnon, Tsutomu Hamuro, James T. B. Crawley, David A. Lane

Blood (2012) 120 (25): 5059–5062.

https://doi.org/10.1182/blood-2012-05-432005

Published: 2012

Includes: Supplemental data

Journal Articles

The Effect of Unpaired Cysteine Residues and the C Domains On the Expression of Von Willebrand Factor

Thomas A J Mckinnon, PhD, Susie Shaperio, MBBS, Agata Anna Nowak, MSc, PhD, M. Laffan, DM, FRCP, FRCPath

Blood (2012) 120 (21): 1078.

https://doi.org/10.1182/blood.V120.21.1078.1078

Published: 2012

Journal Articles

The Role of Sialic Acid in Von Willebrand Function Under Shear Stress

Agata Anna Nowak, MSc, PhD, Michael Laffan, MD, Thomas A J McKinnon, PhD

Blood (2012) 120 (21): 1079.

https://doi.org/10.1182/blood.V120.21.1079.1079

Published: 2012

Journal Articles

O -linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions

Agata A. Nowak, Kevin Canis, Anne Riddell, Michael A. Laffan, Thomas A. J. McKinnon

Blood (2012) 120 (1): 214–222.

https://doi.org/10.1182/blood-2012-02-410050

Published: 2012

Includes: Supplemental data

Journal Articles

The Von Willebrand Factor D'D3 Domains Modulate the Interacton of Platelet Receptor Glycoprotein Ib with the VWF-A1 Domain Under Conditions of Shear Stress

Agata Anna Nowak, MSc, PhD, Amar Shah, BSc(HONS), Michael Laffan, Thomas A J McKinnon, BSc, PhD

Blood (2011) 118 (21): 2212.

https://doi.org/10.1182/blood.V118.21.2212.2212

Published: 2011

Journal Articles

Flow Analysis of Von Willebrand Factor Collagen Binding Mutants

Thomas A J McKinnon, BSc, PhD, Agata Anna Nowak, MSc, PhD, Alina Hua, BSc, Carolyn Millar, MD, PhD, Michael Laffan

Blood (2011) 118 (21): 2213.

https://doi.org/10.1182/blood.V118.21.2213.2213

Published: 2011

Journal Articles

Von Willebrand Factor (VWF) Regulates Angiogenesis: Studies in Blood-Derived Endothelial Progenitor Cells From Von Willebrand's Disease Patients and VWF-Deficient Mice

Richard D Starke, PhD, Koralia Paschalaki, MD, Francesco Ferraro, PhD, Thomas A J McKinnon, PhD, Nicola H Dryden, Elspeth Payne, MBChB, Dorian O Haskard, MD PhD, Alun D Hughes, MD PhD, Daniel Cutler, PhD, Michael Laffan, MD, Anna Maria Randi, MD PhD

Blood (2011) 118 (21): 5311.

https://doi.org/10.1182/blood.V118.21.5311.5311

Published: 2011

Journal Articles

Von Willebrand Factor Binds to the Endothelial Growth Factor Angiopoietin-2 Both within Endothelial Cells and Upon Release From Weibel Palade Bodies

Thomas A J Mckinnon, BSc(HONS), PhD, Richard D Starke, PhD, Kushani Ediriwickrema, BSc(HONS), Anna Maria Randi, MD PhD, Michael Laffan, MD

Blood (2011) 118 (21): 698.

https://doi.org/10.1182/blood.V118.21.698.698

Published: 2011

Journal Articles

Endothelial von Willebrand factor regulates angiogenesis

Richard D. Starke, Francesco Ferraro, Koralia E. Paschalaki, Nicola H. Dryden, Thomas A. J. McKinnon, Rachel E. Sutton, Elspeth M. Payne, Dorian O. Haskard, Alun D. Hughes, Daniel F. Cutler, Mike A. Laffan, Anna M. Randi

Blood (2011) 117 (3): 1071–1080.

https://doi.org/10.1182/blood-2010-01-264507

Published: 2011

Includes: Supplemental data

Journal Articles

Specific N-linked glycosylation sites modulate synthesis and secretion of von Willebrand factor

Thomas A. J. McKinnon, Elizabeth C. Goode, Graeme M. Birdsey, Agata A. Nowak, Alain C. K. Chan, David A. Lane, Michael A. Laffan

Blood (2010) 116 (4): 640–648.

https://doi.org/10.1182/blood-2010-02-267450

Published: 2010

Journal Articles

Expression of terminal α2-6–linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13

Rachel T. McGrath, Thomas A. J. McKinnon, Barry Byrne, Richard O'Kennedy, Virginie Terraube, Emily McRae, Roger J. S. Preston, Mike A. Laffan, James S. O'Donnell

Blood (2010) 115 (13): 2666–2673.

https://doi.org/10.1182/blood-2009-09-241547

Published: 2010

Journal Articles

Terminal α2-6 Linked Sialic Acid Expression On VWF Specifically Enhances Proteolysis by ADAMTS13.

Rachel Therese McGrath, Thomas A J McKinnon, Barry Byrne, Richard O'Kennedy, Michael Laffan, Emily McRae, Roger JS Preston, PhD, James S O'Donnell, MD, PhD

Blood (2009) 114 (22): 30.

https://doi.org/10.1182/blood.V114.22.30.30

Published: 2009

Journal Articles

Characterization of W1745C and S1783A: 2 novel mutations causing defective collagen binding in the A3 domain of von Willebrand factor

Anne F. Riddell, Keith Gomez, Carolyn M. Millar, Gillian Mellars, Saher Gill, Simon A. Brown, Megan Sutherland, Mike A. Laffan, Thomas A. J. McKinnon

Blood (2009) 114 (16): 3489–3496.

https://doi.org/10.1182/blood-2008-10-184317

Published: 2009

Journal Articles

A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF

Sara Zanardelli, Alain C. K. Chion, Evelyn Groot, Peter J. Lenting, Thomas A. J. McKinnon, Mike A. Laffan, Michelle Tseng, David A. Lane

Blood (2009) 114 (13): 2819–2828.

https://doi.org/10.1182/blood-2009-05-224915

Published: 2009

NARROW

Taking AIM

2B or not 2B: art thou autoinhibitory?

Getting under the skin: a new route for factor VIII?

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S

The Effect of Unpaired Cysteine Residues and the C Domains On the Expression of Von Willebrand Factor

The Role of Sialic Acid in Von Willebrand Function Under Shear Stress

O -linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions

The Von Willebrand Factor D'D3 Domains Modulate the Interacton of Platelet Receptor Glycoprotein Ib with the VWF-A1 Domain Under Conditions of Shear Stress

Flow Analysis of Von Willebrand Factor Collagen Binding Mutants

Von Willebrand Factor (VWF) Regulates Angiogenesis: Studies in Blood-Derived Endothelial Progenitor Cells From Von Willebrand's Disease Patients and VWF-Deficient Mice

Von Willebrand Factor Binds to the Endothelial Growth Factor Angiopoietin-2 Both within Endothelial Cells and Upon Release From Weibel Palade Bodies

Endothelial von Willebrand factor regulates angiogenesis

Specific N-linked glycosylation sites modulate synthesis and secretion of von Willebrand factor

Expression of terminal α2-6–linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13

Terminal α2-6 Linked Sialic Acid Expression On VWF Specifically Enhances Proteolysis by ADAMTS13.

Characterization of W1745C and S1783A: 2 novel mutations causing defective collagen binding in the A3 domain of von Willebrand factor

A novel binding site for ADAMTS13 constitutively exposed on the surface of globular VWF

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American Society of Hematology

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