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Journal Articles

Proteomics in Pediatric Acute Myeloid and T-Cell Lymphoblastic Leukemia: Shared Individual Protein Expression Patterns Co-Cluster into Overall Distinct Combinations

Fieke W Hoff, BSc, Anneke D. van Dijk, MD, Yihua Qiu, Eveline S. de Bont, MD PhD, Steven M. Kornblau, MD, Terzah M Horton, MD PhD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-138522

Published: 2020

Journal Articles

Loss of H3K27 Methylation Identifies Poor Outcome in Adult-Onset Acute Myeloid Leukemia

Anneke D. van Dijk, MD, Fieke W Hoff, BSc, Yihua Qiu, Eveline S. de Bont, MD PhD, Sophia W.M. Bruggeman, PhD, Terzah M Horton, MD PhD, Steven M. Kornblau, MD

Blood (2020) 136 (Supplement 1): 24.

https://doi.org/10.1182/blood-2020-139387

Published: 2020

Journal Articles

Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231

Blood (2020) 136 (Supplement 1): 11–12.

https://doi.org/10.1182/blood-2020-134730

Published: 2020

Journal Articles

Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor

Natalia Baran, PhDMD, Alessia Lodi, PhD, Yogesh Dhungana, PhD, Shannon RENEE Sweeney, PhD, Pandey Renu, PhD, Shelley Herbrich, PhD, Fieke W Hoff, BSc, Anna Skwarska, PhD, Mecit Kaplan, MS, Vinitha Mary Kuruvilla, MSc, Antonio Cavazos, MSc, Marc Warmoes, PhD, Shanti Rojas-Sutterlin, PhD, Andre Haman, PhD, Diogo Troggian Veiga, PhD, Ken Furudate, DDM, PhD, Helen Ma, MS, Karine Harutyunyan, PhD, Wentao Yang, Mihai Gagea, MDPhD, Di Du, PhD, May Daher, Luciana Melo Garcia, MD, Sujan Piya, PhD, Vivian Ruvolo, MS, Sriram Shanmugavelandy, Ningping Feng, PhD, Jason P Gay, MS, Ondrej Havranek, MDPhD, Jared Henderson, MS, Katarzyna Tomczak, PhD, Marcin Kaminski, PhD, Daniel Herranz, PharmD, Adolfo Ferrando, MD, PhD, Elias Jabbour, MD, Maria E Di Francesco, PhD, David T. Teachey, MD, Terzah M. Horton, MD PhD, Katayoun Rezvani, MD PhD, Jun J. Yang, PhD, Steven M. Kornblau, MD, Eric Davis, MD, Koichi Takahashi, MD PhD, Michael Andreeff, MD PhD, Joseph R Marszalek, PhD, Philip Lorenzi, PhD, Jiyang Yu, PhD, Stefano Tiziani, PhD, Trang Hoang, PhD, Marina Konopleva, MD PhD

Blood (2020) 136 (Supplement 1): 18–20.

https://doi.org/10.1182/blood-2020-136801

Published: 2020

Journal Articles

Increased Tumor Specific Cytotoxic T Cell Responses and Reversion to a Favorable Cytokine Profile after Treatment in Patients with Newly Diagnosed High Risk Hodgkin Lymphoma Treated on Children's Oncology Group Trial-AHOD1331

Hema Dave, Mimi Mai, Anushree Datar, Gaye Jenkins, BS, Qinglin Pei, PhD, Yue Wu, MS, Frank G. Keller, MD, Sharon M. Castellino, MD MSc, Terzah M Horton, MD PhD, Catherine M. Bollard, MD MBChB

Blood (2020) 136 (Supplement 1): 41–42.

https://doi.org/10.1182/blood-2020-136376

Published: 2020

Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Blood (2019) 134 (Supplement_1): 729.

https://doi.org/10.1182/blood-2019-122784

Published: 2019

Journal Articles

Leukemic Stress Targets the mTOR Pathway to Suppress Residual HSC in the BM Microenvironment

John T Butler, MLS(ASCP), Sherif Abdelhamed, PhD, Lina Gao, PhD, Jeong Lim, PhD, Terzah M Horton, MD PhD, Peter Kurre, MD

Blood (2019) 134 (Supplement_1): 3730.

https://doi.org/10.1182/blood-2019-125682

Published: 2019

Journal Articles

Prognostic Significance of FOXO3 in Pediatric Acute Myeloid Leukemia (AML) Patients Treated with Bortezomib Addition to Standard Therapy: Results from a Children's Oncology Group Phase 3 Clinical Trial

Anneke D. van Dijk, BS, Peter P. Ruvolo, PhD, Fieke W Hoff, BSc, Yihua Qiu, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Anders E. Kolb, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Eveline S. de Bont, MD PhD, Sophia W.M. Bruggeman, PhD, Terzah M Horton, MD PhD, Steven M. Kornblau, MD

Blood (2019) 134 (Supplement_1): 2676.

https://doi.org/10.1182/blood-2019-128579

Published: 2019

Journal Articles

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Jennifer Agrusa, MD, Elmoataz A Abdel Fattah, MBBCh, Howard Lin, BS, Rikhia Chakraborty, PhD, Brooks Scull, MS, Harshal Abhyankar, MS, Nmazuo Wudo Ozuah, MBBS, Olive S. Eckstein, MD, Terzah M Horton, MD PhD, Kala Kamdar, MD, Kenneth L. McClain, MD PhD, Chris Tsz-Kwong Man, PhD, Carl E. Allen, MD PhD

Blood (2019) 134 (Supplement_1): 2773.

https://doi.org/10.1182/blood-2019-125982

Published: 2019

Journal Articles

Proteomic Landscape of Acute Leukemia: A Comparison between ALL and AML in Adults

Fieke W Hoff, BSc, Yihua Qiu, Wendy Hu, PhD, Amina A Qutub, PhD, Eveline S. de Bont, MD PhD, Terzah M Horton, MD PhD, Steven M. Kornblau, MD

Blood (2019) 134 (Supplement_1): 1461.

https://doi.org/10.1182/blood-2019-123470

Published: 2019

Journal Articles

Signatures of Histone Modification Marks and Proteins in Pediatric Acute Myeloid Leukemia: A Comparison to Adults

Anneke D. Van Dijk, Fieke W Hoff, Eveline S. de Bont, MD PhD, YIHUA QIU, Chenyue W. Hu, Amina A Qutub, PhD, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD

Blood (2018) 132 (Supplement 1): 2761.

https://doi.org/10.1182/blood-2018-99-110475

Published: 2018

Journal Articles

AraC-Daunorubicin-Etoposide (ADE) Response Prediction in Pediatric AML Patients Using a Computational Biology Modeling (CBM) Based Precision Medicine Workflow

Christopher R. Cogle, MD, Taher Abbasi, MS, MBA, Neeraj Kumar Singh, B.Tech, Mohammed Sauban, B.E, Rahul K Raman, M.Sc., Robinson Vidva, B.Tech, Anuj Tyagi, M.Sc., Anay Ashok Talawdekar, M.Tech, Arko Das, M.Sc., Steven M. Kornblau, MD, Fieke W Hoff, BSc, Terzah M. Horton, MD PhD, Shireen Vali, PhD

Blood (2018) 132 (Supplement 1): 4034.

https://doi.org/10.1182/blood-2018-99-115775

Published: 2018

Journal Articles

Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia

Lauren K. Meyer, Benjamin Huang, MD, Ritu Roy, PhD, Aaron Hechmer, PhD, Anica Wandler, PhD, Cristina Delgado-Martin, PhD, Adam B. Olshen, PhD, Terzah M. Horton, MD PhD, David T Teachey, MD, Kevin M. Shannon, MD, Michelle L. Hermiston, MD PhD

Blood (2018) 132 (Supplement 1): 913.

https://doi.org/10.1182/blood-2018-99-119930

Published: 2018

Journal Articles

AXL Expression in Pediatric AML Is Associated with Putative LSC and Correlates with a Distinct Set of Proteins Associated with Cell Metabolism, Cell Cycle, and Unfolded Protein Response

Fieke W Hoff, BSc, Peter P. Ruvolo, PhD, Yihua Qiu, Michael Andreeff, MD PhD, Eveline S. de Bont, MD, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD

Blood (2018) 132 (Supplement 1): 2686.

https://doi.org/10.1182/blood-2018-99-112555

Published: 2018

Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML

Sara Mirali, Botham Aaron, Veronique Voisin, PhD, Yihua Qiu, Fieke W Hoff, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Yulia Jitkova, PhD, G. Wei Xu, Neil MacLean, Xiaoming Wang, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD, Steven M Chan, MD PhD, Gary D Bader, Aaron Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): 1335.

https://doi.org/10.1182/blood-2018-99-110869

Published: 2018

Journal Articles

RPPA-Profiling Identifies Patients with Low Phosphorylation Levels of HSF1 at Serine 326 As Potential Candidate for Bortezomib Treatment in Addition to Standard Therapy in Pediatric Acute Myeloid Leukemia

Fieke W Hoff, BSc, Wendy Hu, PhD, Yihua Qiu, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, E. Anders Kolb, MD, Todd A Alonzo, PhD, Amina A Qutub, PhD, Eveline S. de Bont, MD, Sophia W.M. Bruggeman, PhD, Steven M. Kornblau, MD, Terzah M. Horton, MD PhD

Blood (2018) 132 (Supplement 1): 293.

https://doi.org/10.1182/blood-2018-99-110730

Published: 2018

Journal Articles

Proteomic Landscape of De Novo Pediatric Acute Myeloid Leukemia

Fieke W Hoff, BSc, Yihua Qiu, Wendy Hu, PhD, Amina A Qutub, PhD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, E. Anders Kolb, MD, Todd A Alonzo, PhD, Eveline S. de Bont, MD, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD

Blood (2018) 132 (Supplement 1): 294.

https://doi.org/10.1182/blood-2018-99-110796

Published: 2018

Journal Articles

Select Peripheral Blood Cytokine Levels Are Associated with Survival in Pediatric Acute Myeloid Leukemia

Alexandra McLean Stevens, MD, Terzah M. Horton, MD PhD, Michele Redell, MD PhD

Blood (2017) 130 (Supplement 1): 2690.

https://doi.org/10.1182/blood.V130.Suppl_1.2690.2690

Published: 2017

Journal Articles

Targetting CD38 in T Cell Acute Lymphoblastic Leukemia

Karen L. Bride, MD PhD, Tiffaney L. Vincent, Soo-Yeon Im, David M. Barrett, Michelle L. Hermiston, MD PhD, Terzah M. Horton, MD PhD, Mignon L. Loh, MD, Shannon L Maude, MD PhD, Stephan A Grupp, MD PhD, Brent Wood, MDPhD, David T Teachey, MD

Blood (2017) 130 (Supplement 1): 3888.

https://doi.org/10.1182/blood.V130.Suppl_1.3888.3888

Published: 2017

Journal Articles

Atovaquone Demonstrates Single Agent Activity and an Additive Effect in Combination with Cytotoxic Chemotherapy (Cytarabine and Daunorubicin) in AML

Alexandra McLean Stevens, MD, Jaime Omar Munoz, Michael Krueger, Terzah M. Horton, MD PhD, Michele Redell, MD PhD

Blood (2017) 130 (Supplement 1): 3899.

https://doi.org/10.1182/blood.V130.Suppl_1.3899.3899

Published: 2017

NARROW

Proteomics in Pediatric Acute Myeloid and T-Cell Lymphoblastic Leukemia: Shared Individual Protein Expression Patterns Co-Cluster into Overall Distinct Combinations

Loss of H3K27 Methylation Identifies Poor Outcome in Adult-Onset Acute Myeloid Leukemia

Cranial Radiation Can be Eliminated in Most Children with T-Cell Acute Lymphoblastic Leukemia (T-ALL) and Bortezomib Potentially Improves Survival in Children with T-Cell Lymphoblastic Lymphoma (T-LL): Results of Children's Oncology Group (COG) Trial AALL1231

Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor

Increased Tumor Specific Cytotoxic T Cell Responses and Reversion to a Favorable Cytokine Profile after Treatment in Patients with Newly Diagnosed High Risk Hodgkin Lymphoma Treated on Children's Oncology Group Trial-AHOD1331

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Leukemic Stress Targets the mTOR Pathway to Suppress Residual HSC in the BM Microenvironment

Prognostic Significance of FOXO3 in Pediatric Acute Myeloid Leukemia (AML) Patients Treated with Bortezomib Addition to Standard Therapy: Results from a Children's Oncology Group Phase 3 Clinical Trial

Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort

Proteomic Landscape of Acute Leukemia: A Comparison between ALL and AML in Adults

Signatures of Histone Modification Marks and Proteins in Pediatric Acute Myeloid Leukemia: A Comparison to Adults

AraC-Daunorubicin-Etoposide (ADE) Response Prediction in Pediatric AML Patients Using a Computational Biology Modeling (CBM) Based Precision Medicine Workflow

Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia

AXL Expression in Pediatric AML Is Associated with Putative LSC and Correlates with a Distinct Set of Proteins Associated with Cell Metabolism, Cell Cycle, and Unfolded Protein Response

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML

RPPA-Profiling Identifies Patients with Low Phosphorylation Levels of HSF1 at Serine 326 As Potential Candidate for Bortezomib Treatment in Addition to Standard Therapy in Pediatric Acute Myeloid Leukemia

Proteomic Landscape of De Novo Pediatric Acute Myeloid Leukemia

Select Peripheral Blood Cytokine Levels Are Associated with Survival in Pediatric Acute Myeloid Leukemia

Targetting CD38 in T Cell Acute Lymphoblastic Leukemia

Atovaquone Demonstrates Single Agent Activity and an Additive Effect in Combination with Cytotoxic Chemotherapy (Cytarabine and Daunorubicin) in AML

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American Society of Hematology

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American Society of Hematology

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