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Journal Articles

Investigating the Therapeutic Potential of the Novel CBP/p300 Protein Degrader CBPD409 in Multiple Myeloma

Stefan Corradini, Saeideh Arsalani, Mina Maksimos, Ebubechukwu Nwarunma, Glen Watt, Richard Soutar, Mathew Powell, Ross Henderson, Zhixiang Chen, Monica L Guzman, Shaomeng Wang, Abdel K Azab, Mark T Williams

Blood (2024) 144 (Supplement 1): 5828.

https://doi.org/10.1182/blood-2024-209620

Published: 2024

Journal Articles

M2-like Macrophages Transfer Mitochondria to Acute Myeloid Leukaemia Cells Via Tunnelling Nanotubes Promoting Therapy Resistance

Blood (2024) 144 (Supplement 1): 2761.

https://doi.org/10.1182/blood-2024-200028

Published: 2024

Journal Articles

Monotherapy Activity with the First CD20-Targeted Immunotoxin, MT-3724, in Subjects with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Paul A. Hamlin, MD, Vasile Musteata, MD PhD, Mamia Zodelava, MD, Steven I Park, MD, Christine Burnett, Kristina Dabovic, PharmD, Eric T Williams, PhD, Jack P Higgins, PhD, Daniel O. Persky, MD

Blood (2019) 134 (Supplement_1): 4098.

https://doi.org/10.1182/blood-2019-129243

Published: 2019

Journal Articles

Pharmacological Increase of Hb-O 2 Affinity with a Voxelotor Analog Does Not Decrease Brain Tissue pO 2 or Limit O 2 Extraction in Brain Tissues of Sickle Cell Mice

Kobina Dufu, PhD, Alfredo Lucas, MS, Cynthia Rodrigues Muller, PhD, Alexander T Williams, MS, Xinchun Zhang, MS, Peter Rademacher, PhD, Carsten Alt, MSc, PhD, Donna Oksenberg, PhD, Pedro Cabrales, PhD

Blood (2019) 134 (Supplement_1): 3564.

https://doi.org/10.1182/blood-2019-129282

Published: 2019

Journal Articles

Fc Receptor Targeting Reduces Bone Disease in a Pre-Clinical Model of Multiple Myeloma

Mark T Williams, BSc Hons, PhD, Katya Thümmler, PhD, Susan Kitson, Bsc Hons, Richard Soutar, MD PhD, Carl S Goodyear, BSc Hons, PhD

Blood (2015) 126 (23): 3011.

https://doi.org/10.1182/blood.V126.23.3011.3011

Published: 2015

Journal Articles

Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia

Brian Koss, Jeffrey Morrison, Rhonda M. Perciavalle, Harpreet Singh, Jerold E. Rehg, Richard T. Williams, Joseph T. Opferman

Blood (2013) 122 (9): 1587–1598.

https://doi.org/10.1182/blood-2012-06-440230

Published: 2013

Includes: Supplemental data

Journal Articles

Host Thiopurine Methyltransferase Status Affects Mercaptopurine Antileukemic Effectiveness

Laura B. Ramsey, PhD, Laura Janke, DVM, PhD, Mathew Edick, PhD, Cheng Cheng, PhD, Richard T Williams, MBBS, PhD, Charles J. Sherr, MD, PhD, William E. Evans, PharmD, Mary V. Relling, PharmD

Blood (2012) 120 (21): 3560.

https://doi.org/10.1182/blood.V120.21.3560.3560

Published: 2012

Journal Articles

Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome–positive acute lymphoblastic leukemia

Nidal Boulos, Heather L. Mulder, Christopher R. Calabrese, Jeffrey B. Morrison, Jerold E. Rehg, Mary V. Relling, Charles J. Sherr, Richard T. Williams

Blood (2011) 117 (13): 3585–3595.

https://doi.org/10.1182/blood-2010-08-301267

Published: 2011

Includes: Supplemental data

Journal Articles

Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia.

Blood (2009) 114 (22): 182.

https://doi.org/10.1182/blood.V114.22.182.182

Published: 2009

Journal Articles

Developmentally Restricted Protection From Notch1-Induced T Cell Acute Lymphoblastic Leukemia by the Arf Tumor Suppressor.

Emmanuel Volanakis, MD, Richard T Williams, MD, PhD, Charles J. Sherr, MD, PhD

Blood (2009) 114 (22): 143.

https://doi.org/10.1182/blood.V114.22.143.143

Published: 2009

Journal Articles

Stage-specific Arf tumor suppression in Notch1 -induced T-cell acute lymphoblastic leukemia

Emmanuel J. Volanakis, Richard T. Williams, Charles J. Sherr

Blood (2009) 114 (20): 4451–4459.

https://doi.org/10.1182/blood-2009-07-233346

Published: 2009

Includes: Supplemental data

Journal Articles

Acquired Bcr-Abl Kinase Domain Mutations Are Not Responsible for Persistence of Dasatinib-Refractory Disease in Murine Ph+ ALL

Nidal Boulos, PhD, Charles J. Sherr, MD, PhD, Richard T Williams, MD, PhD

Blood (2008) 112 (11): 2924.

https://doi.org/10.1182/blood.V112.11.2924.2924

Published: 2008

Journal Articles

Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia

ChristoPher B Miller, BS, Charles G Mullighan, MBBS(Hons), MSc, MD, Xiaoping Su, PhD, Jing Ma, PhD, Michael Wang, PhD, Jinghui Zhang, Ph.D., Richard T Williams, MD, PhD, James R. Downing, MD

Blood (2008) 112 (11): 293.

https://doi.org/10.1182/blood.V112.11.293.293

Published: 2008

Journal Articles

Haploinsufficiency of Ebf1 Collaborates with BCR-ABL1 to Decrease the Latency of Acute Lymphoblastic Leukemia.

Salil Goorha, MD, Noel T. Lenny, PhD, Christopher B Miller, BS, S. Scott Perry, PhD, Xiaoping Su, PhD, Richard T Williams, MD, PhD, Charles G Mullighan, MBBS(Hons), MSc, MD, James R. Downing, MD

Blood (2008) 112 (11): 3363.

https://doi.org/10.1182/blood.V112.11.3363.3363

Published: 2008

Journal Articles

Ultra-High Resolution Analysis of Genomic Alterations in High-Risk Acute Lymphoblastic Leukemia.

Charles G Mullighan, MBBS(Hons), MSc, MD, Letha A. Phillips, BS, Lesli A. Kiedrowski, Jing Ma, PhD, Richard T. Williams, MD, PhD, Sheila A. Shurtleff, Charles J. Sherr, MD, PhD, James R. Downing, MD

Blood (2008) 112 (11): 2053.

https://doi.org/10.1182/blood.V112.11.2053.2053

Published: 2008

Journal Articles

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1

Daniel Trageser, Cihangir Duy, Lars Klemm, Tanja Gruber, Rahul Nahar, Eugene Park, Yong-mi Kim, John Groffen, Nora Heisterkamp, Wolf-Karsten Hofmann, MD, Giovanni Martinelli, Richard T Williams, MD, PhD, Hassan Jumaa, Markus Muschen

Blood (2008) 112 (11): 15.

https://doi.org/10.1182/blood.V112.11.15.15

Published: 2008

Journal Articles

Cytokine-Dependent Imatinib Resistance in Mouse Bcr-Abl(+), Arf -Null Lymphoblastic Leukemia.

Richard T. Williams, MD, PhD, Willem den Besten, PhD, Nidal Boulos, PhD, Charles J. Sherr, MD, PhD

Blood (2007) 110 (11): 2632.

https://doi.org/10.1182/blood.V110.11.2632.2632

Published: 2007

Journal Articles

Inactivation of the Arf Tumor Suppressor in Mouse BCR-ABL(+) B Cells Greatly Increases the Frequency of Leukemia-Initiating Cells and Confers Imatinib Resistance In Vivo .

Richard T. Williams, MD, PhD, Charles J. Sherr, MD PhD

Blood (2006) 108 (11): 385.

https://doi.org/10.1182/blood.V108.11.385.385

Published: 2006

Journal Articles

A Novel Cytokine, FPT025, Regulates Myeloid Growth and Differentiation Via the M-CSF Receptor.

Blood (2006) 108 (11): 634.

https://doi.org/10.1182/blood.V108.11.634.634

Published: 2006

Journal Articles

Photosensitivity and acute liver injury in myeloproliferative disorder secondary to late-onset protoporphyria caused by deletion of a ferrochelatase gene in hematopoietic cells

Richard G. Goodwin, W. Jonathan Kell, Peter Laidler, C. Colin Long, Sharon D. Whatley, Mark McKinley, Michael N. Badminton, Alan K. Burnett, Geraint T. Williams, George H. Elder

Blood (2006) 107 (1): 60–62.

https://doi.org/10.1182/blood-2004-12-4939

Published: 2006

NARROW

Investigating the Therapeutic Potential of the Novel CBP/p300 Protein Degrader CBPD409 in Multiple Myeloma

M2-like Macrophages Transfer Mitochondria to Acute Myeloid Leukaemia Cells Via Tunnelling Nanotubes Promoting Therapy Resistance

Monotherapy Activity with the First CD20-Targeted Immunotoxin, MT-3724, in Subjects with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Pharmacological Increase of Hb-O 2 Affinity with a Voxelotor Analog Does Not Decrease Brain Tissue pO 2 or Limit O 2 Extraction in Brain Tissues of Sickle Cell Mice

Fc Receptor Targeting Reduces Bone Disease in a Pre-Clinical Model of Multiple Myeloma

Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia

Host Thiopurine Methyltransferase Status Affects Mercaptopurine Antileukemic Effectiveness

Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome–positive acute lymphoblastic leukemia

Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia.

Developmentally Restricted Protection From Notch1-Induced T Cell Acute Lymphoblastic Leukemia by the Arf Tumor Suppressor.

Stage-specific Arf tumor suppression in Notch1 -induced T-cell acute lymphoblastic leukemia

Acquired Bcr-Abl Kinase Domain Mutations Are Not Responsible for Persistence of Dasatinib-Refractory Disease in Murine Ph+ ALL

Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia

Haploinsufficiency of Ebf1 Collaborates with BCR-ABL1 to Decrease the Latency of Acute Lymphoblastic Leukemia.

Ultra-High Resolution Analysis of Genomic Alterations in High-Risk Acute Lymphoblastic Leukemia.

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1

Cytokine-Dependent Imatinib Resistance in Mouse Bcr-Abl(+), Arf -Null Lymphoblastic Leukemia.

Inactivation of the Arf Tumor Suppressor in Mouse BCR-ABL(+) B Cells Greatly Increases the Frequency of Leukemia-Initiating Cells and Confers Imatinib Resistance In Vivo .

A Novel Cytokine, FPT025, Regulates Myeloid Growth and Differentiation Via the M-CSF Receptor.

Photosensitivity and acute liver injury in myeloproliferative disorder secondary to late-onset protoporphyria caused by deletion of a ferrochelatase gene in hematopoietic cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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