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Richard T. Williams
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Journal Articles

Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia

Brian Koss, Jeffrey Morrison, Rhonda M. Perciavalle, Harpreet Singh, Jerold E. Rehg, Richard T. Williams, Joseph T. Opferman
Journal: Blood
Blood (2013) 122 (9): 1587–1598.
https://doi.org/10.1182/blood-2012-06-440230
Published: 2013
Includes: Supplemental data
Journal Articles

Host Thiopurine Methyltransferase Status Affects Mercaptopurine Antileukemic Effectiveness

Laura B. Ramsey, PhD, Laura Janke, DVM, PhD, Mathew Edick, PhD, Cheng Cheng, PhD, Richard T Williams, MBBS, PhD, Charles J. Sherr, MD, PhD, William E. Evans, PharmD, Mary V. Relling, PharmD
Journal: Blood
Blood (2012) 120 (21): 3560.
https://doi.org/10.1182/blood.V120.21.3560.3560
Published: 2012
Journal Articles

Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome–positive acute lymphoblastic leukemia

Nidal Boulos, Heather L. Mulder, Christopher R. Calabrese, Jeffrey B. Morrison, Jerold E. Rehg, Mary V. Relling, Charles J. Sherr, Richard T. Williams
Journal: Blood
Blood (2011) 117 (13): 3585–3595.
https://doi.org/10.1182/blood-2010-08-301267
Published: 2011
Includes: Supplemental data
Journal Articles

Rearrangement of CRLF2 in B-Progenitor and Down Syndrome Associated Acute Lymphoblastic Leukemia.

Charles G. Mullighan, MBBS(Hons), MSc, MD, J. Racquel Collins-Underwood, PhD, Letha A Phillips, BS, Michael G. Loudin, Wei Liu, Jinghui Zhang, Ph.D., Jing Ma, PhD, Elaine Coustan-Smith, MS, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Jinjun Cheng, MB, MS, Fady M. Mikhail, MD, PhD, Julia Meyer, Richard T Williams, MD, PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Giuseppe Basso, MD, Andrea Pession, Ching-Hon Pui, MD, Susana C. Raimondi, PhD, Stephen P Hunger, MD, James R. Downing, MD, William L. Carroll, MD, Karen R. Rabin, MD
Journal: Blood
Blood (2009) 114 (22): 182.
https://doi.org/10.1182/blood.V114.22.182.182
Published: 2009
Journal Articles

Developmentally Restricted Protection From Notch1-Induced T Cell Acute Lymphoblastic Leukemia by the Arf Tumor Suppressor.

Emmanuel Volanakis, MD, Richard T Williams, MD, PhD, Charles J. Sherr, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 143.
https://doi.org/10.1182/blood.V114.22.143.143
Published: 2009
Journal Articles

Stage-specific Arf tumor suppression in Notch1 -induced T-cell acute lymphoblastic leukemia

Emmanuel J. Volanakis, Richard T. Williams, Charles J. Sherr
Journal: Blood
Blood (2009) 114 (20): 4451–4459.
https://doi.org/10.1182/blood-2009-07-233346
Published: 2009
Includes: Supplemental data
Journal Articles

Acquired Bcr-Abl Kinase Domain Mutations Are Not Responsible for Persistence of Dasatinib-Refractory Disease in Murine Ph+ ALL

Nidal Boulos, PhD, Charles J. Sherr, MD, PhD, Richard T Williams, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2924.
https://doi.org/10.1182/blood.V112.11.2924.2924
Published: 2008
Journal Articles

Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia

ChristoPher B Miller, BS, Charles G Mullighan, MBBS(Hons), MSc, MD, Xiaoping Su, PhD, Jing Ma, PhD, Michael Wang, PhD, Jinghui Zhang, Ph.D., Richard T Williams, MD, PhD, James R. Downing, MD
Journal: Blood
Blood (2008) 112 (11): 293.
https://doi.org/10.1182/blood.V112.11.293.293
Published: 2008
Journal Articles

Haploinsufficiency of Ebf1 Collaborates with BCR-ABL1 to Decrease the Latency of Acute Lymphoblastic Leukemia.

Salil Goorha, MD, Noel T. Lenny, PhD, Christopher B Miller, BS, S. Scott Perry, PhD, Xiaoping Su, PhD, Richard T Williams, MD, PhD, Charles G Mullighan, MBBS(Hons), MSc, MD, James R. Downing, MD
Journal: Blood
Blood (2008) 112 (11): 3363.
https://doi.org/10.1182/blood.V112.11.3363.3363
Published: 2008
Journal Articles

Ultra-High Resolution Analysis of Genomic Alterations in High-Risk Acute Lymphoblastic Leukemia.

Charles G Mullighan, MBBS(Hons), MSc, MD, Letha A. Phillips, BS, Lesli A. Kiedrowski, Jing Ma, PhD, Richard T. Williams, MD, PhD, Sheila A. Shurtleff, Charles J. Sherr, MD, PhD, James R. Downing, MD
Journal: Blood
Blood (2008) 112 (11): 2053.
https://doi.org/10.1182/blood.V112.11.2053.2053
Published: 2008
Journal Articles

Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1

Daniel Trageser, Cihangir Duy, Lars Klemm, Tanja Gruber, Rahul Nahar, Eugene Park, Yong-mi Kim, John Groffen, Nora Heisterkamp, Wolf-Karsten Hofmann, MD, Giovanni Martinelli, Richard T Williams, MD, PhD, Hassan Jumaa, Markus Muschen
Journal: Blood
Blood (2008) 112 (11): 15.
https://doi.org/10.1182/blood.V112.11.15.15
Published: 2008
Journal Articles

Cytokine-Dependent Imatinib Resistance in Mouse Bcr-Abl(+), Arf -Null Lymphoblastic Leukemia.

Richard T. Williams, MD, PhD, Willem den Besten, PhD, Nidal Boulos, PhD, Charles J. Sherr, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2632.
https://doi.org/10.1182/blood.V110.11.2632.2632
Published: 2007
Journal Articles

Inactivation of the Arf Tumor Suppressor in Mouse BCR-ABL(+) B Cells Greatly Increases the Frequency of Leukemia-Initiating Cells and Confers Imatinib Resistance In Vivo .

Richard T. Williams, MD, PhD, Charles J. Sherr, MD PhD
Journal: Blood
Blood (2006) 108 (11): 385.
https://doi.org/10.1182/blood.V108.11.385.385
Published: 2006
Journal Articles

Genetic Interaction of the BCR-ABL Oncogene and the ARF Tumor Suppressor in Ph+ Lymphoid Leukemia.

Richard T. Williams, MD, PhD, Martine F. Roussel, PhD, Charles J. Sherr, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 240.
https://doi.org/10.1182/blood.V106.11.240.240
Published: 2005