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Journal Articles

Hottip -Mediated R-Loops Regulate CTCF TAD Boundary to Control WNT/b-Catenin Pathway in AML Genome

Huacheng Luo, PhD, Ganqian Zhu, PhD, Xiaoyan Ma, MD PhD, David F. Claxton, MD, Yi Qiu, PhD, Mingjiang Xu, MDPhD, Suming Huang, PhD

Blood (2020) 136 (Supplement 1): 44–45.

https://doi.org/10.1182/blood-2020-137816

Published: 2020

Journal Articles

Functional Complementation between β-Catenin and Hoxa9 Sustains HSC Self-Renewal in a Prmt1-Dependent Manner

Jennifer Lynch, PhD, Clemence Virely, PhD, Priscilla Lau, PhD, Huacheng Luo, PhD, Suming Huang, PhD, Eric Chi Wai So, PhD

Blood (2019) 134 (Supplement_1): 449.

https://doi.org/10.1182/blood-2019-131052

Published: 2019

Journal Articles

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Mark Sellin, Ryan Mack, Matthew C. Rhodes, Lei Zhang, PhD, Wei Wei, Peter Breslin, PhD, Stephanie Berg, DO, Suming Huang, PhD, Richard Taylor, PhD, Jiwang Zhang, MD

Blood (2019) 134 (Supplement_1): 2666.

https://doi.org/10.1182/blood-2019-132030

Published: 2019

Journal Articles

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Huacheng Luo, Ganqian Zhu, PhD, Tsz Kan Fung, Yi Qiu, PhD, Mingjiang Xu, MD PhD, Chi Wai Eric So, Suming Huang, PhD

Blood (2019) 134 (Supplement_1): 277.

https://doi.org/10.1182/blood-2019-127323

Published: 2019

Journal Articles

Ripk3 Signaling Regulates Hematopoietic Stem Cell Number and Function during Stress

Lei Zhang, PhD, Huacheng Luo, PhD, Jing Li, Hong-Min Ni, Mark Sellin, Feng Zhang, Jun Zhang, Peter Breslin, PhD, Wei Wei, William Small, Jr., Wen-Xin Ding, Suming Huang, PhD, Jiwang Zhang, MD

Blood (2019) 134 (Supplement_1): 3714.

https://doi.org/10.1182/blood-2019-131332

Published: 2019

Journal Articles

Residual TP53 Mutation Contributes to Chemoresistance through Clonal Expansion in Acute Myeloid Leukemia

Bowen Yan, PhD, Qinwei Chen, MS, Jianfeng Xu, PhD, Wei Li, PhD, Bing Xu, Suming Huang, PhD, Yi Qiu, PhD

Blood (2019) 134 (Supplement_1): 2731.

https://doi.org/10.1182/blood-2019-127511

Published: 2019

Journal Articles

Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34 -/Lo MLL-Rearranged Leukemia

Tsz Kan Fung, Bernd Zeisig, Magdalena Zarowiecki, Huacheng Luo, Chiou Tsun Tsai, Boban Stanojevic, Claire Lynn, Anskar Y.-H. Leung, MD PhD, Jan Zuna, Marketa Zaliova, MD PhD, Martin Bornhaeuser, MD, Malte Von Bonin, Boris Lenhard, Suming Huang, PhD, Ghulam J. Mufti, Chi Wai Eric So

Blood (2019) 134 (Supplement_1): 3203.

https://doi.org/10.1182/blood-2019-125078

Published: 2019

Journal Articles

GATA-1 Deacetylation and Interaction with HDAC1 Is Critical for GATA-1 Mediated Gene Transcription

Bowen Yan, Ph. D, Suming Huang, PhD, Yi Qiu, PhD

Blood (2017) 130 (Supplement 1): 945.

https://doi.org/10.1182/blood.V130.Suppl_1.945.945

Published: 2017

Journal Articles

Disruption of CTCF Boundary Remodels Chromatin Domain and Reprograms HOX Gene Transcription in Acute Myeloid Leukemia

Huacheng Luo, PhD, Fei Wang, MDPhD, Haoli Li, PhD, Qinghua Du, MD, Bowen Yan, Ph. D, Shi Chen, Baoan Chen, MDPhD, Yi Qiu, PhD, Mingjiang Xu, MDPhD, Suming Huang, PhD

Blood (2017) 130 (Supplement 1): 244.

https://doi.org/10.1182/blood.V130.Suppl_1.244.244

Published: 2017

Journal Articles

Epigenetic Drugs Selectively Target a Population of AML Cells Which Are Positive for CD123 Cell Surface Marker and Are Chemoresistant

Bowen Yan, Ph. D, Suming Huang, PhD, Yi Qiu, PhD

Blood (2017) 130 (Supplement 1): 3929.

https://doi.org/10.1182/blood.V130.Suppl_1.3929.3929

Published: 2017

Journal Articles

Disregulation of CTCF Boundary at the HOX Locus Enhances Sensitity to Multiple Drug Treatment in Myeloid Malignancies

Jie Zha, MD, Huacheng Luo, PhD, Yi Qiu, PhD, Suming Huang, PhD

Blood (2017) 130 (Supplement 1): 3816.

https://doi.org/10.1182/blood.V130.Suppl_1.3816.3816

Published: 2017

Journal Articles

Hematologic Malignancies and Carbapenem Resistance: A Multicentre Retrospective Study from Chinese People

Bing Xu, MD PhD, Suming Huang, PhD, Lingli He, Guoshu Chen, Zhifeng Li, Pengcheng Shi, Xutao Guo, Zhihong Fang, Yan Wang, Jie Li, Yong Zhou

Blood (2017) 130 (Supplement 1): 4826.

https://doi.org/10.1182/blood.V130.Suppl_1.4826.4826

Published: 2017

Journal Articles

The TAL1 Short Isoform Generated By PRMT1-Mediated Alternative RNA Splicing Promotes Erythroid Differentiation

Shuiling Jin, MD, Ngoc-Tung Tran, PhD, Hairui Su, BS, Suming Huang, PhD, Xinyang Zhao, PhD, Yanyan Liu, MDand PhD

Blood (2016) 128 (22): 1249.

https://doi.org/10.1182/blood.V128.22.1249.1249

Published: 2016

Journal Articles

Persistent Clonal Expansion of Vδ3 and Vδ4 T Cells in T-ALL Case with Minimal Residual Disease after HSCT

Ling Xu, Jianyu Weng, PhD, Xin Huang, Shaohua Chen, Suxia Geng, Lijian Yang, Suijing Wu, PhD, Suming Huang, PhD, Du Xin, PhD, Yangqiu Li, MD

Blood (2014) 124 (21): 5885.

https://doi.org/10.1182/blood.V124.21.5885.5885

Published: 2014

Journal Articles

Lincrna Hotset Regulates Hox Gene Transcription and Promotes Early Hematopoietic Fates

Changwang Deng, Ying Li, PhD, Besabeh Tusi, PhD, Wei Jian, Bhavita Patel, PhD, Yangqiu Li, MD, Jorg Bungert, Lei Zhou, PhD, Yi Qiu, PhD, Suming Huang, PhD

Blood (2014) 124 (21): 1573.

https://doi.org/10.1182/blood.V124.21.1573.1573

Published: 2014

Journal Articles

HDAC1 Can Deacetylate GATA-1 and Regulates Its Activity through a FOG-1 Independent Manner

Bowen Yan, PhD, Tao Yang, Suming Huang, PhD, Yi Qiu, PhD

Blood (2014) 124 (21): 5125.

https://doi.org/10.1182/blood.V124.21.5125.5125

Published: 2014

Journal Articles

A T-Cell Specific Element Activates the TAL1 Oncogene Via an Interchromosomal Interaction During Leukemogenesis

Yuanyuan Kang, Bhavita Patel, BS, MS, Kairong Cui, Keji Zhao, Yi Qiu, Suming Huang, PhD

Blood (2012) 120 (21): 3507.

https://doi.org/10.1182/blood.V120.21.3507.3507

Published: 2012

Journal Articles

CTCF Mediated Enhancer and Promoter Interaction Regulates Differential Expression of TAL1 Oncogene in Normal and Malignant Hematopoiesis

Bhavita Patel, BS, MS, Changwang Deng, Michael Litt, Mariana St. Just Riberio, Kairong Cui, Yuanyuan Kang, Yi Qiu, Keji Zhao, Suming Huang, PhD

Blood (2012) 120 (21): 281.

https://doi.org/10.1182/blood.V120.21.281.281

Published: 2012

Journal Articles

Role of hSET1 Complex in Epigenetic Controls of HoxB4 Expression and Development of Hematopoietic Stem Cells

Changwang Deng, Ying Li, Shermi Liang, Tal Salz, Yi Qiu, Robert Roeder, PhD, Keji Zhao, Jorg Bungert, Suming Huang, PhD

Blood (2011) 118 (21): 212.

https://doi.org/10.1182/blood.V118.21.212.212

Published: 2011

Journal Articles

Essential Role for the MAML1 Co-Activator In T-ALL

Chunxia Cao, Ph.D., Liang Tian, Jian-Liang Li, Ph.D., James D. Griffin, MD, Suming Huang, PhD, Lizi Wu, PhD

Blood (2010) 116 (21): 2501.

https://doi.org/10.1182/blood.V116.21.2501.2501

Published: 2010

NARROW

Hottip -Mediated R-Loops Regulate CTCF TAD Boundary to Control WNT/b-Catenin Pathway in AML Genome

Functional Complementation between β-Catenin and Hoxa9 Sustains HSC Self-Renewal in a Prmt1-Dependent Manner

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Ripk3 Signaling Regulates Hematopoietic Stem Cell Number and Function during Stress

Residual TP53 Mutation Contributes to Chemoresistance through Clonal Expansion in Acute Myeloid Leukemia

Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34 -/Lo MLL-Rearranged Leukemia

GATA-1 Deacetylation and Interaction with HDAC1 Is Critical for GATA-1 Mediated Gene Transcription

Disruption of CTCF Boundary Remodels Chromatin Domain and Reprograms HOX Gene Transcription in Acute Myeloid Leukemia

Epigenetic Drugs Selectively Target a Population of AML Cells Which Are Positive for CD123 Cell Surface Marker and Are Chemoresistant

Disregulation of CTCF Boundary at the HOX Locus Enhances Sensitity to Multiple Drug Treatment in Myeloid Malignancies

Hematologic Malignancies and Carbapenem Resistance: A Multicentre Retrospective Study from Chinese People

The TAL1 Short Isoform Generated By PRMT1-Mediated Alternative RNA Splicing Promotes Erythroid Differentiation

Persistent Clonal Expansion of Vδ3 and Vδ4 T Cells in T-ALL Case with Minimal Residual Disease after HSCT

Lincrna Hotset Regulates Hox Gene Transcription and Promotes Early Hematopoietic Fates

HDAC1 Can Deacetylate GATA-1 and Regulates Its Activity through a FOG-1 Independent Manner

A T-Cell Specific Element Activates the TAL1 Oncogene Via an Interchromosomal Interaction During Leukemogenesis

CTCF Mediated Enhancer and Promoter Interaction Regulates Differential Expression of TAL1 Oncogene in Normal and Malignant Hematopoiesis

Role of hSET1 Complex in Epigenetic Controls of HoxB4 Expression and Development of Hematopoietic Stem Cells

Essential Role for the MAML1 Co-Activator In T-ALL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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