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Sudha Janaki-Raman
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Journal Articles

α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia

Scott Evan Millman, Almudena Chaves-Perez, Sudha Janaki-Raman, Yu-Jui Ho, John P Morris IV, Varun Narendra, Chi-Chao Chen, Benjamin T Jackson, Jossie J Yashinskie, Riccardo Mezzadra, Tessa I Devine, Valentin J. A. Barthet, Michelle Saoi, Timour Baslan, Sha Tian, Zohar Sachs, Lydia WS Finley, Justin R Cross, Scott W Lowe
Journal: Blood
Blood blood.2024025245.
https://doi.org/10.1182/blood.2024025245
Published: 2024
Includes: Supplemental data
Journal Articles

Fructose Treatment Targets Myeloid Leukemogenesis in IDH2 Mutants By Exhausting Alpha-Ketoglutarate Pools

Angela Maria Savino, Briana Turner, Sangmoo Jeong, Tanya Schild, Xuejing Yang, Hanzhi Luo, Rachel Chirayil, Quinlan Cullen, Mandy Chan, Grace Han, Kathryn Chang, Sudha Janaki Raman, Justin R Cross, Kayvan Keshari, Michael G Kharas
Journal: Blood
Blood (2022) 140 (Supplement 1): 2966–2967.
https://doi.org/10.1182/blood-2022-164626
Published: 2022
Journal Articles

Ogdh Is a Genetic Vulnerability and Therapeutic Target in Acute Myeloid Leukemia

Scott E Millman, Almudena Chaves-Perez, John P Morris, IV, Chi-Chao Chen, Yu-Jui Ho, Sudha Janaki Raman, Jossie J Yashinskie, Riccardo Mezzadra, Varun Narendra, Sha Tian, Alexandra Wuest, Wei Luan, Justin R Cross, Lydia WS Finley, Scott W Lowe
Journal: Blood
Blood (2022) 140 (Supplement 1): 5846–5847.
https://doi.org/10.1182/blood-2022-166414
Published: 2022