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Journal Articles

Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

Ryan H. Moy, Austin P. Huffman, Lee P. Richman, Lisa Crisalli, Ximi K. Wang, James A. Hoxie, Rosemarie Mick, Stephen G. Emerson, Yi Zhang, Robert H. Vonderheide, David L. Porter, Ran Reshef

Blood (2017) 129 (7): 906–916.

https://doi.org/10.1182/blood-2016-08-735076

Published: 2017

Includes: Supplemental data

Journal Articles

The Orphan Nuclear Receptor Nr4a1 Specifies Long-Term, Myeloid-Biased HSCs and Responds To PGE2

Ruben Land, BS, Anna Rayne, BS, Ashley Vanderbeck, BS, Trevor Barlowe, BS, Sophie Eiger, Undergraduate, Shwetha Manjunath, Matthew Gross, B.S., Nicole Cunningham, B.S., Stephen G. Emerson, MD, PhD, Jenni A. Punt, VMD, PhD

Blood (2013) 122 (21): 3675.

https://doi.org/10.1182/blood.V122.21.3675.3675

Published: 2013

Journal Articles

NF-Y is necessary for hematopoietic stem cell proliferation and survival

Gerd Bungartz, Hannah Land, David T. Scadden, Stephen G. Emerson

Blood (2012) 119 (6): 1380–1389.

https://doi.org/10.1182/blood-2011-06-359406

Published: 2012

Includes: Supplemental data

Journal Articles

A Phase 1 Dose Escalation Study of Infusion of Ex Vivo CD3/CD28 Costimulated Umbilical Cord Blood-Derived T Cells in Adults Undergoing Transplantation for Advanced Hematologic Malignancies

Elizabeth Hexner, MD, Selina M. Luger, MD, James K. Mangan, MD, PhD, Noelle V. Frey, MD, Grace R Jeschke, Dale Frank, MD, Ran Reshef, MD, Alison W. Loren, MD, Steven C. Goldstein, MD, Misha Rosenbach, M.D., Christopher Nowaczyk, Mindy Schuster, M.D., Edward A. Stadtmauer, MD, Bruce L Levine, PhD, Carl H. June, MD, Stephen G. Emerson, MD, PhD, David L. Porter, MD

Blood (2011) 118 (21): 3032.

https://doi.org/10.1182/blood.V118.21.3032.3032

Published: 2011

Journal Articles

A Novel Nr4a1 GFP Reporter System Reveals That Nr4a1 Expression Identifies Long-Term Hematopoietic Stem Cells

Ruben Land, Undergraduate, Trevor Barlowe, Undergraduate, Shwetha Manjunath, B.S., Sophie Eiger, Undergraduate, Matthew Gross, B.S., Russell Garrett, PhD, Nicole Cunningham, B.S., Stephen G. Emerson, MD, PhD, Jenni A. Punt, VMD, PhD

Blood (2011) 118 (21): 2339.

https://doi.org/10.1182/blood.V118.21.2339.2339

Published: 2011

Journal Articles

IFNs Upregulate Sca-1 and Block Proliferation in Murine Hematopoietic Stem and Progenitor Cells,

Kaitlyn Shank, Yusup Shin, B.S., Carson Wills, Nicole Cunningham, B.S., Alevtina Domashenko, PhD, Russell Garrett, PhD, Jenni A. Punt, VMD, PhD, Stephen G. Emerson, MD, PhD

Blood (2011) 118 (21): 3394.

https://doi.org/10.1182/blood.V118.21.3394.3394

Published: 2011

Journal Articles

Inhibition of Lymphocyte Trafficking Using a CCR5 Antagonist – Final Results of a Phase I/II Study

Ran Reshef, MD, Selina M. Luger, MD, Elizabeth O. Hexner, MD, Alison W. Loren, MD, Noelle V. Frey, MD, Steven C. Goldstein, MD, Sunita D. Nasta, MD, Edward A. Stadtmauer, MD, Jacqueline Smith, CRNP, Rosemarie Mick, MS, Daniel F. Heitjan, PhD, James A. Hoxie, MD, Stephen G. Emerson, MD, PhD, Robert H. Vonderheide, MD, PhD, David L. Porter, MD

Blood (2011) 118 (21): 1011.

https://doi.org/10.1182/blood.V118.21.1011.1011

Published: 2011

Journal Articles

Notch signaling is a critical regulator of allogeneic CD4 + T-cell responses mediating graft-versus-host disease

Yi Zhang, Ashley R. Sandy, Jina Wang, Vedran Radojcic, Gloria T. Shan, Ivy T. Tran, Ann Friedman, Koji Kato, Shan He, Shuaiying Cui, Elizabeth Hexner, Dale M. Frank, Stephen G. Emerson, Warren S. Pear, Ivan Maillard

Blood (2011) 117 (1): 299–308.

https://doi.org/10.1182/blood-2010-03-271940

Published: 2011

Includes: Supplemental data

Journal Articles

Prevention of Graft-Versus-Host Disease by Inhibition of Lymphocyte Trafficking Using a CCR5 Antagonist

Ran Reshef, MD, Selina M. Luger, MD, Alison W. Loren, MD, Noelle V. Frey, MD, Steven C. Goldstein, MD, Elizabeth O. Hexner, MD, Edward A. Stadtmauer, MD, Jacqueline Smith, CRNP, Rosemarie Mick, MS, Daniel F. Heitjan, PhD, Susan E. Shetzline, PhD, Gwenn-ael H. Danet-Desnoyers, PhD, Stephen G. Emerson, MD, PhD, James A. Hoxie, MD, Robert H. Vonderheide, MD, PhD, David L. Porter, MD

Blood (2010) 116 (21): 673.

https://doi.org/10.1182/blood.V116.21.673.673

Published: 2010

Journal Articles

Differential Regulation of Expression of the Anti-Leukemogenic Orphan Nuclear Receptor Nur77 (nr4a1) In HSCs, CLPs, and CMPs

Yusup Shin, Shwetha Manjunath, Matthew Gross, Ruben Land, Russell Garrett, PhD, Stephen G. Emerson, MD, PhD, Jenni A. Punt, VMD, PhD

Blood (2010) 116 (21): 4782.

https://doi.org/10.1182/blood.V116.21.4782.4782

Published: 2010

Journal Articles

TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells

Alevtina D. Domashenko, Gwenn Danet-Desnoyers, Alissa Aron, Martin P. Carroll, Stephen G. Emerson

Blood (2010) 116 (15): 2676–2683.

https://doi.org/10.1182/blood-2010-03-273441

Published: 2010

Journal Articles

Alloreactive CD8 + Effector T Cells Proliferate and Persist Upon Chronic Exposure to Alloantigens through Reactivation of Stem Cell Transcriptional Programs.

Koji Kato, MD, Shuaiying Cui, Rork Kuick, Shin Mineishi, MD, Elizabeth Hexner, MD, James LM Ferrara, MD, DSc, Victor E Marquez, PhD, Stephen G. Emerson, MD, PhD, Yi Zhang, MD, PhD

Blood (2009) 114 (22): 2444.

https://doi.org/10.1182/blood.V114.22.2444.2444

Published: 2009

Journal Articles

Poly I:C Stimulates Sca-1 Expression in Murine Bone Marrow and Increases the Number of Phenotypic Hematopoietic Stem Cells.

Russell Garrett, Ph.D., Gerd Bungartz, Alevtina Domashenko, Stephen G. Emerson, MD, PhD

Blood (2009) 114 (22): 2504.

https://doi.org/10.1182/blood.V114.22.2504.2504

Published: 2009

Journal Articles

Notch Signaling Is a Critical Regulator of Allogeneic T Cell Responses Mediating Graft-Versus-Host Disease.

Yi Zhang, MD, PhD, Ashley R Sandy, BS, Jina Wang, Koji Kato, MD, Shan He, Ivy Tran, Gloria Tran Shan, Ann Friedman, Elizabeth Hexner, MD, Stephen G. Emerson, MD, PhD, Warren S. Pear, MD, PhD, Ivan Maillard, MD, PhD

Blood (2009) 114 (22): 230.

https://doi.org/10.1182/blood.V114.22.230.230

Published: 2009

Journal Articles

Osteoblast-Stem Cell Contact Is Required for B-Lymphopoietic Proliferation, Not Differentiation.

Asia Gobourne, Heidi Bretscher, Alevtina Domashenko, Ph.D., Gerd Bungartz, Ph.D., Russell Garrett, Ph.D., Stephen G. Emerson, MD, PhD

Blood (2009) 114 (22): 3635.

https://doi.org/10.1182/blood.V114.22.3635.3635

Published: 2009

Journal Articles

NF-Ya Is Essential for Hematopoieic Stem Cell Proliferation.

Gerd Bungartz, Russell Garrett, Ph.D., Stephen G. Emerson, MD, PhD

Blood (2009) 114 (22): 1507.

https://doi.org/10.1182/blood.V114.22.1507.1507

Published: 2009

Journal Articles

Transduction of Human CD34+ Cells with Recombinant TAT-NF-YA Protein Enhances Their Ex Vivo Expansion and Repopulating Potential in NOD/SCID Mice

Alevtina Domashenko, Gwenn Danet-Desnoyers, Russell Sundby, Stephen G. Emerson

Blood (2008) 112 (11): 3528.

https://doi.org/10.1182/blood.V112.11.3528.3528

Published: 2008

Journal Articles

Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders

Elizabeth O. Hexner, Cynthia Serdikoff, Mahfuza Jan, Cezary R. Swider, Candy Robinson, Shi Yang, Thelma Angeles, Stephen G. Emerson, Martin Carroll, Bruce Ruggeri, Pawel Dobrzanski

Blood (2008) 111 (12): 5663–5671.

https://doi.org/10.1182/blood-2007-04-083402

Published: 2008

Includes: Supplemental data

Journal Articles

Down Regulation of CXC Chemokine Receptor 3 Impedes the Ability of Anti-CXCR3 Antibody To Block Graft-Versus-Host Disease.

Shan He, MA, Qi Cao, MA, Min Jin, BA, Stephen G. Emerson, MD, PhD, Yi Zhang, MD, PhD, Yanyun Zhang, MD, PhD

Blood (2007) 110 (11): 3235.

https://doi.org/10.1182/blood.V110.11.3235.3235

Published: 2007

Journal Articles

Determination of the Role and Mechanism of the Transcription Factor NF-Y in Murine Hematopoietic Stem Cell Biology.

Gerd Bungartz, PhD, Stephen G. Emerson, M.D., Ph.D.

Blood (2007) 110 (11): 2234.

https://doi.org/10.1182/blood.V110.11.2234.2234

Published: 2007

NARROW

Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis

The Orphan Nuclear Receptor Nr4a1 Specifies Long-Term, Myeloid-Biased HSCs and Responds To PGE2

NF-Y is necessary for hematopoietic stem cell proliferation and survival

A Phase 1 Dose Escalation Study of Infusion of Ex Vivo CD3/CD28 Costimulated Umbilical Cord Blood-Derived T Cells in Adults Undergoing Transplantation for Advanced Hematologic Malignancies

A Novel Nr4a1 GFP Reporter System Reveals That Nr4a1 Expression Identifies Long-Term Hematopoietic Stem Cells

IFNs Upregulate Sca-1 and Block Proliferation in Murine Hematopoietic Stem and Progenitor Cells,

Inhibition of Lymphocyte Trafficking Using a CCR5 Antagonist – Final Results of a Phase I/II Study

Notch signaling is a critical regulator of allogeneic CD4 + T-cell responses mediating graft-versus-host disease

Prevention of Graft-Versus-Host Disease by Inhibition of Lymphocyte Trafficking Using a CCR5 Antagonist

Differential Regulation of Expression of the Anti-Leukemogenic Orphan Nuclear Receptor Nur77 (nr4a1) In HSCs, CLPs, and CMPs

TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells

Alloreactive CD8 + Effector T Cells Proliferate and Persist Upon Chronic Exposure to Alloantigens through Reactivation of Stem Cell Transcriptional Programs.

Poly I:C Stimulates Sca-1 Expression in Murine Bone Marrow and Increases the Number of Phenotypic Hematopoietic Stem Cells.

Notch Signaling Is a Critical Regulator of Allogeneic T Cell Responses Mediating Graft-Versus-Host Disease.

Osteoblast-Stem Cell Contact Is Required for B-Lymphopoietic Proliferation, Not Differentiation.

NF-Ya Is Essential for Hematopoieic Stem Cell Proliferation.

Transduction of Human CD34+ Cells with Recombinant TAT-NF-YA Protein Enhances Their Ex Vivo Expansion and Repopulating Potential in NOD/SCID Mice

Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders

Down Regulation of CXC Chemokine Receptor 3 Impedes the Ability of Anti-CXCR3 Antibody To Block Graft-Versus-Host Disease.

Determination of the Role and Mechanism of the Transcription Factor NF-Y in Murine Hematopoietic Stem Cell Biology.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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