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Shinpei Harada
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Journal Articles

Early Initiation of Calcineurin Inhibitor Induces CD8 + Transitory Exhausted-like and CD4 + Cytotoxic T Cells, Maintaining Responsiveness to PD-1 Blockade and Contributing to the Development of Chronic Gvhd after Post-Transplant Cyclophosphamide

Hajime Senjo, Daigo Hashimoto, Shihori Tsukamoto, Keisuke Kojima, Shimpei I Kubota, Ayumu Ito, Tomoe Ichiki, Satomi Okada, Yumika Saito, Toru Miyajima, Shinpei Harada, Wenyu Li, Zixuan Zhang, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Yoshinori Hasegawa, Yoshihiro Inamoto, Masaaki Murakami, Takahiro Fukuda, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 903.
https://doi.org/10.1182/blood-2024-197873
Published: 2024
Journal Articles

Ropeginterferon Alfa-2b Induces Apoptosis and Differentiation of Leukemia Stem Cells and Separates GVL Effects from Gvhd after Allogeneic Hematopoietic Cell Transplantation

Yumika Saito, Daigo Hashimoto, Keisuke Kojima, Shihori Tsukamoto, Tomoe Ichiki, Toru Miyajima, Wenyu Li, Shinpei Harada, Zixuan Zhang, Hajime Senjo, Yuta Hasegawa, Takahide Ara, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 902.
https://doi.org/10.1182/blood-2024-201237
Published: 2024
Journal Articles

Gvhd-Induced Inflammatory Memory in Intestinal Stem Cells Enhances IFN-γ-Induced Antigen Presentation and Apoptosis of Intestinal Epithelial Cells

Toru Miyajima, Daigo Hashimoto, Keisuke Kojima, Shihori Tsukamoto, Tomoe Ichiki, Yumika Saito, Wenyu Li, Zixuan Zhang, Shinpei Harada, Hajime Senjo, Yuki Yokoi, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Kiminori Nakamura, Koji Taniguchi, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 260.
https://doi.org/10.1182/blood-2024-202926
Published: 2024
Journal Articles

Reduced FDG Uptake in the Brain on Baseline 18FDG PET/CT Predicts Worse Prognosis of Newly Diagnosed Intravascular Large B-Cell Lymphoma and Advanced-Stage Diffuse Large B-Cell Lymphoma

Hajime Senjo, Shinpei Harada, Koh Izumiyama, Hideki Goto, Shiro Watanabe, Keito Suto, Masayo Yamamoto, Kazuya Sato, Yasutaka Kakinoki, Tomoyuki Saga, Akio Shigematsu, Hiroto Horiguchi, Mutsumi Takahata, Reiki Ogasawara, Satoshi Yamamoto, Keisuke Yamaguchi, Kentaro Wakasa, Tetsuyuki Igarashi, Yoshihito Haseyama, Shinichi Ito, Katsuya Fujimoto, Junichi Hashiguchi, Junichi Sugita, Masao Nakagawa, Kenji Hirata, Takuto Miyagishima, Daigo Hashimoto, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 3096.
https://doi.org/10.1182/blood-2024-204976
Published: 2024
Journal Articles

Addition of High-Dose Methotrexate to Initial Chemotherapy Improved Treatment Outcome of Patients with Newly Diagnosed Intravascular Large B-Cell Lymphoma: A Multicenter, Retrospective Study

Shinpei Harada, Hideki Goto, Hajime Senjo, Keito Suto, Koh Izumiyama, Masayo Yamamoto, Kazuya Sato, Yasutaka Kakinoki, Tomoyuki Saga, Akio Shigematsu, Hiroto Horiguchi, Mutsumi Takahata, Reiki Ogasawara, Satoshi Yamamoto, Keisuke Yamaguchi, Kentaro Wakasa, Tetsuyuki Igarashi, Yoshihito Haseyama, Shinichi Ito, Katsuya Fujimoto, Junichi Hashiguchi, Masao Nakagawa, Daigo Hashimoto, Takanori Teshima
Journal: Blood
Blood (2023) 142 (Supplement 1): 440.
https://doi.org/10.1182/blood-2023-181183
Published: 2023
Journal Articles

Delayed Initiation of Calcineurin Inhibitor Is Critical for Tolerance Induction By Posttransplant Cyclophosphamide

Hajime Senjo, Daigo Hashimoto, Satomi Okada, Shimpei I Kubota, Ayumu Ito, Takashi Tanaka, Yumika Saito, Toru Miyajima, Wenyu Li, Zixuan Zhang, Shinpei Harada, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Yoshinori Hasegawa, Yoshihiro Inamoto, Masaaki Murakami, Takahiro Fukuda, Takanori Teshima
Journal: Blood
Blood (2023) 142 (Supplement 1): 2041.
https://doi.org/10.1182/blood-2023-181560
Published: 2023
Journal Articles

Baseline 18 f-Fluorodeoxyglucose PET/CT Radiomics Predicts Outcome in Newly Diagnosed Intravascular Large B-Cell Lymphoma

Shinpei Harada, Hideki Goto, Hajime Senjo, Keito Suto, Shiro Watanabe, Koh Izumiyama, Masayo Yamamoto, Kazuya Sato, Yasutaka Kakinoki, Tomoyuki Saga, Akio Shigematsu, Hiroto Horiguchi, Mutsumi Takahata, Reiki Ogasawara, Satoshi Yamamoto, Keisuke Yamaguchi, Kentaro Wakasa, Tetsuyuki Igarashi, Yoshihito Haseyama, Shinichi Ito, Katsuya Fujimoto, Junichi Hashiguchi, Masao Nakagawa, Daigo Hashimoto, Takanori Teshima
Journal: Blood
Blood (2023) 142 (Supplement 1): 6321.
https://doi.org/10.1182/blood-2023-188507
Published: 2023
Journal Articles

Ferroptosis Inhibition Generates TCF-1 + CAR-T Cells with Enhanced Persistence and Cytotoxicity

Shinpei Harada, Daigo Hashimoto, Yumika Saito, Toru Miyajima, Wenyu Li, Hajime Senjo, Zixuan Zhang, Ryo Kikuchi, Masahiro Chiba, Hiroyuki Ohigashi, Takahide Ara, Masao Nakagawa, Takanori Teshima
Journal: Blood
Blood (2023) 142 (Supplement 1): 97.
https://doi.org/10.1182/blood-2023-179444
Published: 2023
Journal Articles

Calcineurin inhibitor inhibits tolerance induction by suppressing terminal exhaustion of donor T cells after allo-HCT

Hajime Senjo, Shinpei Harada, Shimpei I. Kubota, Yuki Tanaka, Takahiro Tateno, Zixuan Zhang, Satomi Okada, Xuanzhong Chen, Ryo Kikuchi, Naoki Miyashita, Masahiro Onozawa, Hideki Goto, Tomoyuki Endo, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Yoshinori Hasegawa, Masaaki Murakami, Takanori Teshima, Daigo Hashimoto
Journal: Blood
Blood (2023) 142 (5): 477–492.
https://doi.org/10.1182/blood.2023019875
Published: 2023
Includes: Supplemental data
Journal Articles

Incidentally Detected Complex Karyotypic Abnormalities in the Bone Marrow Provide a Clue to Diagnosing Intravascular Large B-Cell Lymphoma

Shinpei Harada, Hideki Goto, Hajime Senjo, Keito Suto, Koh Izumiyama, Masayo Yamamoto, Kazuya Sato, Yasutaka Kakinoki, Tomoyuki Saga, Akio Shigematsu, Hiroto Horiguchi, Mutsumi Takahata, Reiki Ogasawara, Satoshi Yamamoto, Keisuke Yamaguchi, Kentaro Wakasa, Tetsuyuki Igarashi, Yoshihito Haseyama, Shinichi Ito, Katsuya Fujimoto, Junichi Hashiguchi, Masao Nakagawa, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 790–791.
https://doi.org/10.1182/blood-2022-169519
Published: 2022
Journal Articles

Novel Simple Prognostic Index (NJHSG-PI) Can Effectively Predict Prognosis in Patients with Newly Diagnosed DLBCL : A Real World Analysis across 14 Cancer Centers in Japan

Koh Izumiyama, Shinpei Harada, Hajime Senjo, Reiki Ogasawara, Tomoyuki Saga, Tetsuyuki Igarashi, Kentaro Wakasa, Ikumi Kasahara, Yukari Takeda, Keisuke Yamaguchi, Akio Shigematsu, Mutsumi Takahata, Katsuya Fujimoto, Yoshihito Haseyama, Takahiro Nagashima, Hajime Sakai, Yasutaka Kakinoki, Mitsutoshi Kurosawa, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 782–784.
https://doi.org/10.1182/blood-2022-165038
Published: 2022
Journal Articles

Calcineurin Inhibitors Inhibit Tolerance Induction By Suppressing Terminal Differentiation of Donor Exhausted T Cells after Allogeneic SCT

Hajime Senjo, Daigo Hashimoto, Shinpei Kubota, Yuki Tanaka, Shinpei Harada, Kazuki Yoneda, Zixuan Zhang, Xuanzhong Chen, Ryo Kikuchi, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Yoshinori Hasegawa, Masaaki Murakami, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 1159–1160.
https://doi.org/10.1182/blood-2022-158842
Published: 2022
Journal Articles

Elevated FDG Uptake in the Lung Is a Characteristic Finding of Intravascular Large B-Cell Lymphoma

Shinpei Harada, Hideki Goto, Hajime Senjo, Keito Suto, Shiro Watanabe, Yuko Uchiyama, Koh Izumiyama, Masayo Yamamoto, Kazuya Sato, Yasutaka Kakinoki, Tomoyuki Saga, Akio Shigematsu, Hiroto Horiguchi, Mutsumi Takahata, Reiki Ogasawara, Satoshi Yamamoto, Keisuke Yamaguchi, Kentaro Wakasa, Tetsuyuki Igarashi, Yoshihito Haseyama, Shinichi Ito, Katsuya Fujimoto, Junichi Hashiguchi, Masao Nakagawa, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 6713–6714.
https://doi.org/10.1182/blood-2022-169208
Published: 2022
Journal Articles

Intercellular Mitochondrial Transfer Enhances Metabolic Fitness and Anti-Tumor Effects of CAR T Cells

Shinpei Harada, Daigo Hashimoto, Hajime Senjo, Kazuki Yoneda, Zixuan Zhang, Xuanzhong Chen, Ryo Kikuchi, Masahiro Chiba, Hiroyuki Ohigashi, Takahide Ara, Masao Nakagawa, Masashi Suganuma, Rick C. Tsai, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 2356–2357.
https://doi.org/10.1182/blood-2022-162535
Published: 2022
Journal Articles

Dynamic Change of Peripheral Blood WT1-mRNA within Three Cycles of Azacitidine Therapy Predicts Treatment Response in High-Risk Myelodysplastic Syndrome

Shinpei Harada, Masahiro Onozawa, Daisuke Hidaka, MD, Shota Yokoyama, Hajime Senjo, MD, Shogo Takahashi, MD, Reiki Ogasawara, MDPhD, Akio Mori, Shuichi Ota, Takeshi Kondo, MD PhD, Takanori Teshima, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-138377
Published: 2020