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Journal Articles

The Potent Dihydroorotate Dehydrogenase Inhibitor, Hosu-53, Exhibits Compelling Monotherapy Efficacy in Multiple Myeloma and Augments CD47 Targeted Therapy

Gerard Hilinski, Blaise Stearns, Sandip Vibhute, Tiffany Hughes, Susheela Tridandapani, Megan E. Johnstone, Thomas E. Goodwin, Jeffrey Patrick, Chad E. Bennett, Don Benson, John C. Byrd, Ola A. Elgamal, Erin K. Hertlein

Blood (2023) 142 (Supplement 1): 4692.

https://doi.org/10.1182/blood-2023-189238

Published: 2023

Journal Articles

Hosu-53, a Novel Potent Dihydroorotate Dehydrogenase Inhibitor Accentuates CD47 Blockade Therapy Resulting in Long Term Survival in Acute Myeloid Leukemia

Ola A Elgamal, Sandip Vibhute, Blaise Stearns, Susheela Tridandapani, Thomas E Goodwin, Gerard Hilinski, Chad Bennett, Jeffrey Patrick, Erin Hertlein, John C. Byrd

Blood (2022) 140 (Supplement 1): 3322–3323.

https://doi.org/10.1182/blood-2022-165611

Published: 2022

Journal Articles

Preclinical Development of Hosu-53, a Novel Potent Dihydroorotate Dehydrogenase Inhibitor with Impressive Single Agent Efficacy and Combination Approaches in Hematological Malignancy

Erin Hertlein, Chad Bennett, Ola A Elgamal, Sandip Vibhute, Sharyn Baker, Thomas E Goodwin, Don M. Benson, Jr., Christopher Coss, Jeffrey Patrick, Gerald Hilinski, John C. Byrd

Blood (2022) 140 (Supplement 1): 10695–10696.

https://doi.org/10.1182/blood-2022-167671

Published: 2022