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Samantha J. Busfield
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Journal Articles

First-in Man, Phase 1 Study of CSL362 (Anti-IL3Rα / Anti-CD123 Monoclonal Antibody) in Patients with CD123+ Acute Myeloid Leukemia (AML) in CR at High Risk for Early Relapse

B. Douglas Smith, MD, Gail J. Roboz, MD, Roland B. Walter, MD PhD, Jessica K. Altman, MD, Anna Ferguson, BSN, RN, Tania J. Curcio, R.N, Kaysey F. Orlowski, Linda Garrett, RN, Samantha J Busfield, PhD, Megan Barnden, PhD, Brad Sedgmen, PhD, Souravi Ghosh, PhD, Sarah Hosback, PhD, Roslyn Davis, MSc, Allison Dyson, BSc, Sue Dasen, MS, Mark DeWitte, VMD, Debra M. Bensen-Kennedy, MD, Andrew W. Roberts, MBBS, PhD
Journal: Blood
Blood (2014) 124 (21): 120.
https://doi.org/10.1182/blood.V124.21.120.120
Published: 2014
Journal Articles

High Plasma Levels of TGF-α and IL-6 at Diagnosis Predict Early Molecular Response Failure and Transformation in CML

Eva Nievergall, PhD, John Reynolds, PhD, Chung H Kok, PhD, Dale Watkins, PhD, Mark Biondo, PhD, Samantha J Busfield, PhD, Gino Vairo, PhD, David T Yeung, BSc, MBBS, FRACP, FRCPA, Angel Lopez, PhD, Devendra K Hiwase, MBBS, MD PhD FRACP, FRCPA, Deborah L White, PhD FFSc (RCPA), Timothy P Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2014) 124 (21): 1788.
https://doi.org/10.1182/blood.V124.21.1788.1788
Published: 2014
Journal Articles

Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells

Eva Nievergall, Hayley S. Ramshaw, Agnes S. M. Yong, Mark Biondo, Samantha J. Busfield, Gino Vairo, Angel F. Lopez, Timothy P. Hughes, Deborah L. White, Devendra K. Hiwase
Journal: Blood
Blood (2014) 123 (8): 1218–1228.
https://doi.org/10.1182/blood-2012-12-475194
Published: 2014
Includes: Supplemental data
Journal Articles

Effective Elimination of CML Progenitor and Stem Cells Through Combination of α-CD123 Antibody-Dependent Cell-Mediated Cytotoxicity and Tyrosine Kinase Inhibitor Treatment

Eva Nievergall, PhD, Deborah L. White, PhD, FFSc(RCPA), Agnes S.M. Yong, MD, PhD, Hayley S. Ramshaw, PhD, Samantha J. Busfield, PhD, Gino Vairo, PhD, Angel F. Lopez, MBBS, PhD, Timothy P. Hughes, MD, MBBS, Devendra K. Hiwase, MBBS, MD, PhD, FRACP, FRCPA
Journal: Blood
Blood (2012) 120 (21): 32.
https://doi.org/10.1182/blood.V120.21.32.32
Published: 2012
Journal Articles

CSL362: A Monoclonal Antibody to Human Interleukin-3 Receptor (CD123), Optimized for NK Cell-Mediated Cytotoxicity of AML Stem Cells

Samantha J. Busfield, PhD, Mark Biondo, PhD, Mae Wong, PhD, Hayley S. Ramshaw, PhD, Erwin M Lee, PhD, Kirstee Martin, PhD, Souravi Ghosh, PhD, Hal Braley, Vesna Tomasetig, Con Panousis, PhD, Gino Vairo, PhD, Andrew W. Roberts, MBBS, PhD, Simon Z. He, MBBS, Naomi Sprigg, Daniel Thomas, MBBS, PhD, Mark DeWitte, VMD, Richard B. Lock, PhD, Angel F. Lopez, MBBS, PhD, Andrew Nash, PhD
Journal: Blood
Blood (2012) 120 (21): 3598.
https://doi.org/10.1182/blood.V120.21.3598.3598
Published: 2012
Journal Articles

A Neutralizing Antibody (CSL362) Against the Interleukin-3 Receptor α-Chain Augments the Efficacy of a Cytarabine/Daunorubicin Induction-Type Therapy in Preclinical Xenograft Models of Acute Myelogenous Leukemia

Erwin M Lee, PhD, Dean Yee, PhD, Samantha J Busfield, PhD, Gino Vairo, PhD, Richard B. Lock, PhD
Journal: Blood
Blood (2012) 120 (21): 3599.
https://doi.org/10.1182/blood.V120.21.3599.3599
Published: 2012
Journal Articles

A Phase 1 and Correlative Biological Study of CSL360 (anti-CD123 mAb) in AML

Andrew W. Roberts, MBBS, PhD, Simon He, MBBS, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Mark S Hertzberg, MBBS, FRACP, FRCP, PhD, Simon T S Durrant, MRCS, MBBS, MRCP, FRCP, David Ritchie, MBChB, FRACP, FRCPA, PhD, Ian D. Lewis, MBBS, PhD, FRACP, FRCPA, Paula Marlton, MBBS, FRACP, FRCPA, Andrew J McLachlan, PhD, Trina M Yeadon, PhD, Samantha J Busfield, PhD, Megan J Barnden, PhD, Roslyn Davis, BSc(Hons), Sarah Hosback, PhD, Danijela Mirosa, PhD, Mark Biondo, PhD, Simone Bamford, MBBS, FRACGP, Mark DeWitte, VMD, Russell Basser, MBBS, MD, FRACP
Journal: Blood
Blood (2008) 112 (11): 2956.
https://doi.org/10.1182/blood.V112.11.2956.2956
Published: 2008