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Journal Articles

Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis

Fernanda Gutierrez-Rodrigues, PhD, Isabel Beerman, PhD, Emma M. Groarke, MD, Bhavisha A Patel, MD, Nina Spitofsky, Diego Quinones Raffo, MSc, Sachiko Kajigaya, PhD, Luigi Ferrucci, MD PhD, Neal S. Young, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-139874

Published: 2020

Journal Articles

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Qingguo Liu, MD PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Fengkui Zhang, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 4997.

https://doi.org/10.1182/blood-2019-123249

Published: 2019

Journal Articles

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Shouguo Gao, PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3706.

https://doi.org/10.1182/blood-2019-123204

Published: 2019

Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3735.

https://doi.org/10.1182/blood-2019-124774

Published: 2019

Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3738.

https://doi.org/10.1182/blood-2019-127359

Published: 2019

Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Fernanda Gutierrez-Rodrigues, PhD, Flávia S Donaires, PhD, André Pinto, Alana Vicente, MD, Laura Dillon, PhD, Diego V Clé, MDPhD, Bárbara Santana, Maria del Pilar Fernandez Ibanez, Danielle M. Townsley, MD MSc, Sachiko Kajigaya, PhD, Christopher S. Hourigan, DPhil FACP FRCP, James N. Cooper, MD, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 539.

https://doi.org/10.1182/blood-2018-99-115430

Published: 2018

Journal Articles

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Shouguo Gao, PhD, Zhijie Wu, MD PhD, Carrie Diamond, MD, Bradley Arnold, BS, Valentina Giudice, MD, Lemlem Alemu, BS, John Barrett, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2404.

https://doi.org/10.1182/blood-2018-99-115166

Published: 2018

Journal Articles

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Fernanda Gutierrez-Rodrigues, PhD, Carrie Diamond, MD, Ruba Shalhoub, André Pinto, Flávia S Donaires, PhD, Diego V Clé, MD PhD, Luiz Guilherme Darrigo, PhD, Luiz Fernando Catto, MD, Xing Fan, MD, Maria del Pilar Fernandez Ibanez, Sachiko Kajigaya, PhD, Cynthia E. Dunbar, MD, Carmem M. S. Bonfim, MD, Danielle M. Townsley, MD MSc, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2587.

https://doi.org/10.1182/blood-2018-99-115026

Published: 2018

Journal Articles

Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS)

Alana Vicente, MD, Fernanda Gutierrez-Rodrigues, PhD, Valentina Giudice, MD, Zhijie Wu, MD PhD, Sachiko Kajigaya, PhD, Maria del Pilar Fernandez Ibanez, Maher Albitar, MD, Barbara Weinstein, RN, Katherine R. Calvo, MD PhD, Danielle M. Townsley, MDMSc, Phillip Scheinberg, MD, Cynthia E. Dunbar, MD, Neal S. Young, MD, Thomas Winkler, MD

Blood (2018) 132 (Supplement 1): 229.

https://doi.org/10.1182/blood-2018-99-119780

Published: 2018

Journal Articles

Crispr/Cas9-Induced DNMT3A Mutations in the K562 Human Leukemic Cell Line As a Model of DNMT3A -Mutated Leukemogenesis

Lauren G. Banaszak, BS, Valentina Giudice, MD, Xin Zhao, MD PhD, Zhijie Wu, MD, Kohei Hosokawa, MD PhD, Keyvan Keyvanfar, BS, Danielle Townsley, MD, Sachiko Kajigaya, PhD, Neal S. Young

Blood (2016) 128 (22): 2704.

https://doi.org/10.1182/blood.V128.22.2704.2704

Published: 2016

Journal Articles

Crispr/Cas9-Mediated ASXL1 knockout in U937 Human Leukemic Cells Perturbs Myeloid Differentiation

Zhijie Wu, MD, Xin Zhao, MD PhD, Lauren G. Banaszak, BS, Keyvan Keyvanfar, BS, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2016) 128 (22): 1529.

https://doi.org/10.1182/blood.V128.22.1529.1529

Published: 2016

Journal Articles

Single-Cell RNA-Seq Reveals the Differentiation Hierarchy of Normal Human Bone Marrow and a Distinct Transcriptome Signature of Monosomy 7 Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Xingmin Feng, PhD, Delong Liu, PhD, Sachiko Kajigaya, PhD, Zhijie Wu, MD, Qingguo Liu, MD, Keyvan Keyvanfar, BS, Marie J. Desierto, BS, Danielle M. Townsley, MD, Xujing Wang, PhD, Neal S. Young, MD

Blood (2016) 128 (22): 574.

https://doi.org/10.1182/blood.V128.22.574.574

Published: 2016

Journal Articles

T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

Kohei Hosokawa, MDPhD, Sachiko Kajigaya, PhD, Keyvan Keyvanfar, BS, Qiao Wangmin, BS, Yanling Xie, MS, Olga Rios, RN, Barbara Weinstein, RN, Maria del Pilar Fernandez Ibanez, BS, Danielle M. Townsley, MD, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2016) 128 (22): 1042.

https://doi.org/10.1182/blood.V128.22.1042.1042

Published: 2016

Journal Articles

Heterozygous RTEL1 variants in Patients with Bone Marrow Failure Associate with Telomere Dysfunction in the Absence of Telomere Shortening

Fernanda Gutierrez-Rodrigues, MSc, PharmD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Maria del Pilar Fernandez Ibanez, MS, Marie J. Desierto, BS, Keyvan Keyvanfar, BS, Zejuan Li, MD PhD, Soma Das, PhD, Rodrigo T. Calado, MD PhD, Danielle M. Townsley, MD, Neal S. Young

Blood (2016) 128 (22): 1044.

https://doi.org/10.1182/blood.V128.22.1044.1044

Published: 2016

Journal Articles

Fluorescent Cell Barcoding As New Flow Cytometric Technique for Multiplexed Phenotyping and Signaling Profiling in Hematologic Patients

Valentina Giudice, MD, Xingmin Feng, PhD, Sachiko Kajigaya, PhD, Angelique Biancotto, PhD, Neal S. Young

Blood (2016) 128 (22): 5033.

https://doi.org/10.1182/blood.V128.22.5033.5033

Published: 2016

Journal Articles

A Plasma microRNA Signature As a Biomarker for Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Marie J. Desierto, BS, Maria del Pilar Fernandez Ibanez, BS, Olga Rios, RN, Barbara Weinstein, RN, Phillip Scheinberg, MD, Danielle M. Townsley, MD, Neal S. Young, MD

Blood (2016) 128 (22): 728.

https://doi.org/10.1182/blood.V128.22.728.728

Published: 2016

Journal Articles

Activity of the Telomerase Inhibitor GRN163L (Imetelstat) on Acute Myeloblastic Leukemia Blasts Is Enhanced By DNA Methyltransferase Inhibitors Irrespective of TERT Promoter Methylation Status

Caroline R Cantilena, BA, Xin Zhao, MD PhD, Sachiko Kajigaya, PhD, Neil Dunavin, MD, Xin Tian, PhD, Stephen A. Strickland, MD, Bipin N. Savani, MD, Sanjay R. Mohan, MD, Katayoun Rezvani, MDPhD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Minoo Battiwalla, MDMS, Sawa Ito, MD, Austin John Barrett, MDFRCP,FRCPath

Blood (2015) 126 (23): 1267.

https://doi.org/10.1182/blood.V126.23.1267.1267

Published: 2015

Journal Articles

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Kohei Hosokawa, MDPhD, Sachiko Kajigaya, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Marie Desierto, Olga Rios, Barbara Weinstein, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2015) 126 (23): 3608.

https://doi.org/10.1182/blood.V126.23.3608.3608

Published: 2015

Journal Articles

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Kohei Hosokawa, MDPhD, Pawel Muranski, MD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Baoying Liu, PhD, Jared Knickelbein, MD, Keyvan Keyvanfar, BS, Bogdan Dumitriu, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Mariana J. Kaplan, MD, Robert B. Nussenblatt, MD, Austin John Barrett, MDFRCP,FRCPath, John O'Shea, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3613.

https://doi.org/10.1182/blood.V126.23.3613.3613

Published: 2015

NARROW

Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome (MDS)

Crispr/Cas9-Induced DNMT3A Mutations in the K562 Human Leukemic Cell Line As a Model of DNMT3A -Mutated Leukemogenesis

Crispr/Cas9-Mediated ASXL1 knockout in U937 Human Leukemic Cells Perturbs Myeloid Differentiation

Single-Cell RNA-Seq Reveals the Differentiation Hierarchy of Normal Human Bone Marrow and a Distinct Transcriptome Signature of Monosomy 7 Cells

T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

Heterozygous RTEL1 variants in Patients with Bone Marrow Failure Associate with Telomere Dysfunction in the Absence of Telomere Shortening

Fluorescent Cell Barcoding As New Flow Cytometric Technique for Multiplexed Phenotyping and Signaling Profiling in Hematologic Patients

A Plasma microRNA Signature As a Biomarker for Acquired Aplastic Anemia

Activity of the Telomerase Inhibitor GRN163L (Imetelstat) on Acute Myeloblastic Leukemia Blasts Is Enhanced By DNA Methyltransferase Inhibitors Irrespective of TERT Promoter Methylation Status

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

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American Society of Hematology

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American Society of Hematology

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