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Journal Articles

Single-Cell Whole-Genome Sequencing after Chemotherapeutic Treatment Reveals Cell Type-Specific Mutational Burdens

Lucca L.M. Derks, Inge Van Der Werf, Laurianne Trabut, Eline Bertrums, Jurrian De Kanter, Axel Rosendahl Huber, Ruben Van Boxtel
Journal: Blood
Blood (2023) 142 (Supplement 1): 4136.
https://doi.org/10.1182/blood-2023-189460
Published: 2023
Journal Articles

Transient Differentiation-State Plasticity during Initiation of Pediatric Acute Lymphoblastic Leukemia

Vera M Poort, Rico Hagelaar, Mark van Roosmalen, Laurianne Trabut, Jessica G.C.A.M. Buijs-Gladdines, Diego Montiel González, Bram van Wijk, Jules P.P. Meijerink, Ruben Van Boxtel
Journal: Blood
Blood (2023) 142 (Supplement 1): 42.
https://doi.org/10.1182/blood-2023-188891
Published: 2023
Journal Articles

Single-Cell Multi-Omics to Infer Hierarchical Ancestry and Organization of Subclones in Acute Lymphoblastic Leukemia

Vera M Poort, Rico Hagelaar, Diego Montiel González, Jessica G.C.A.M. Buijs-Gladdines, Laurianne Trabut, Bram van Wijk, Jules PP Meijerink, Ruben Van Boxtel
Journal: Blood
Blood (2022) 140 (Supplement 1): 5909–5910.
https://doi.org/10.1182/blood-2022-166205
Published: 2022
Journal Articles

Retrospective Lineage Tracing of Pediatric Acute Myeloid Leukemia Using Single-Cell Whole Genome Sequencing

Eline J.M. Bertrums, Sjors Middelkamp, Inge M. van der Werf, Freek Manders, Arianne M. Brandsma, Niels M. Groenen, Mark Verheul, Markus J. van Roosmalen, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink, Bianca F. Goemans, Ruben Van Boxtel
Journal: Blood
Blood (2022) 140 (Supplement 1): 8725–8726.
https://doi.org/10.1182/blood-2022-166051
Published: 2022
Journal Articles

Mutational Consequences of Chemotherapy in Hematopoietic Stem and Progenitor Cells of Pediatric Cancer Patients

Eline J.M. Bertrums, Axel Rosendahl-Huber, Jurrian de Kanter, Anais C.N. van Leeuwen, Flavia Peci, C. Michel Zwaan, Bianca F. Goemans, Ruben Van Boxtel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2154.
https://doi.org/10.1182/blood-2021-148471
Published: 2021
Journal Articles

Deregulation of Splicing in Pediatric Acute Myeloid Stem and Progenitor Cells

Phoebe Mondala, Inge Van Der Werf, Larisa Balaian, Kathleen Steel, Luisa Ladel, Cayla Mason, Raymond Diep, Jacqueline Cloos, Gertjan Kaspers, Markus J van Roosmalen, Ruben Van Boxtel, Warren Chan, Adam Mark, Mary Donohoe, James La Clair, Peggy Wentworth, Kathleen Fisch, Leslie A Crews, Thomas Whisenant, Michael Burkart, Catriona Jamieson
Journal: Blood
Blood (2021) 138 (Supplement 1): 2227.
https://doi.org/10.1182/blood-2021-154120
Published: 2021
Journal Articles

Increased Mutagenesis during Fetal Hematopoietic Development in Down Syndrome

Karlijn Hasaart, MSc, Freek Manders, MSc, Susana Chuva de Sousa Lopes, PhD, Ruben Van Boxtel, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1186.
https://doi.org/10.1182/blood-2019-122855
Published: 2019
Journal Articles

IL-7 Activates a STAT5/PIM1 Axis to Promote T-Cell Acute Lymphoblastic Leukemia Proliferation and Viability in a Bcl-2-Independent Manner

Ribeiro Daniel, PhD, Alice Melão, Msc, Ruben van Boxtel, PhD, Cristina Santos, PhD, Ana Silva, PhD, Milene C Silva, PhD, Bruno António Cardoso, PhD, Paul J. Coffer, PhD Prof, Joao Barata, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 914.
https://doi.org/10.1182/blood-2018-99-113778
Published: 2018
Journal Articles

The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Martine van Keimpema, Leonie J. Grüneberg, Michal Mokry, Ruben van Boxtel, Menno C. van Zelm, Paul Coffer, Steven T. Pals, Marcel Spaargaren
Journal: Blood
Blood (2015) 126 (18): 2098–2109.
https://doi.org/10.1182/blood-2015-02-626176
Published: 2015
Includes: Supplemental data
Journal Articles

FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells

Martine van Keimpema, Leonie J. Grüneberg, Michal Mokry, Ruben van Boxtel, Jan Koster, Paul J. Coffer, Steven T. Pals, Marcel Spaargaren
Journal: Blood
Blood (2014) 124 (23): 3431–3440.
https://doi.org/10.1182/blood-2014-01-553412
Published: 2014
Includes: Supplemental data