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Roberta iacucci Ostini
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Journal Articles

Safety of 20Gy Total Marrow Irradiation Based Conditioning Regimen for Hematopoietic Cell Transplantation with T Cell Adoptive Immunotherapy

Francesco Zorutti, Simonetta Saldi, Loredana Ruggeri, Valerio Viglione, Christian Fulcheri, Rebecca Sembenico, Matteo Caridi, Anna Castaldo, Antonella Mancusi, Claudio Zucchetti, Susanta Hui, Federico Camilli, Tiziana Zei, Roberta Iacucci Ostini, Enrico Karim Jardini, Eni Hoxha, Antonella Monaldi, Anthony S. Stein, Gianluca Ingrosso, Andrea Velardi, Massimo Fabrizio Martelli, Maria Paola Martelli, Cynthia Aristei, Alessandra Carotti, Antonio Pierini
Journal: Blood
Blood (2024) 144 (Supplement 1): 269.
https://doi.org/10.1182/blood-2024-203492
Published: 2024
Journal Articles

Treg Selection from G-CSF Stimulated Donors Improves Outcomes of Immune-Suppression Free HLA-Haploidentical Hematopoietic Cell Transplantation with T Cell Adoptive Immunotherapy

Antonio Pierini, Loredana Ruggeri, Valerio Viglione, Simonetta Saldi, Rebecca Sembenico, Caridi Matteo, Francesco Zorutti, Anna Castaldo, Alessandra Cipiciani, Tiziana Zei, Roberta iacucci Ostini, Antonella Mancusi, Enrico Karim Jardini, Eni Hoxha, Adelmo Terenzi, Valeria Cardinali, Roberta La Starza, Cristina Mecucci, Andrea Velardi, Massimo Fabrizio Martelli, Maria Paola Martelli, Cynthia Aristei, Alessandra Carotti
Journal: Blood
Blood (2024) 144 (Supplement 1): 147.
https://doi.org/10.1182/blood-2024-202474
Published: 2024
Journal Articles

HLA-Matched Treg/Tcon Allogeneic Hematopoietic Cell Transplantation Is Safe and Ensures Remarkable Chronic GvHD/Leukemia Free Survival in High-Risk Leukemia Patients

Antonio Pierini, Loredana Ruggeri, Simonetta Saldi, Sara Tricarico, Francesca Marzuttini, Valerio Viglione, Rebecca Sembenico, Tiziana Zei, Roberta Iacucci Ostini, Antonella Mancusi, Roberto Limongello, Olivia Minelli, Gianluca Ingrosso, Adelmo Terenzi, Maria Paola Martelli, Maurizio Caniglia, Cristina Mecucci, Andrea Velardi, Massimo Fabrizio Martelli, Cynthia Aristei, Alessandra Carotti
Journal: Blood
Blood (2022) 140 (Supplement 1): 2133–2134.
https://doi.org/10.1182/blood-2022-169351
Published: 2022
Journal Articles

Acute GvHD after HLA-Haploidentical Hematopoietic Cell Transplantation with Regulatory and Conventional T Cell Immunotherapy Does Not Adversely Affect Transplantation Outcomes

Samanta Bonato, Rachele Del Sordo, Antonella Mancusi, Adelmo Terenzi, Tiziana Zei, Roberta Iacucci Ostini, Sara Tricarico, Sara Piccinelli, Mario Griselli, Francesca Marzuttini, Valerio Viglione, Eleonora Torti, Rebecca Sembenico, Roberto Limongello, Mara Merluzzi, Eni Hoxha, Sara Ciardelli, Rosaria Sola, Franca Falzetti, Michele Giansanti, Massimo Fabrizio Martelli, Loredana Ruggeri, Alessandra Carotti, Andrea Velardi, Antonio Pierini
Journal: Blood
Blood (2021) 138 (Supplement 1): 2885.
https://doi.org/10.1182/blood-2021-152839
Published: 2021
Journal Articles

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Sara Piccinelli, Antonella Mancusi, PhD, Eni Hoxha, Loredana Ruggeri, MD, Franca Falzetti, MD, Alessandra Carotti, MD, Adelmo Terenzi, MD, Samanta Bonato, MD, Matteo Paradiso, MD, Tiziana Zei, Roberta Iacucci Ostini, Barbara Bigerna, Brunangelo Falini, MD PhD, Mauro Di Ianni, MD PhD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1917.
https://doi.org/10.1182/blood-2019-125715
Published: 2019
Journal Articles

Activation of Regulatory T Cells with IL-2 and TNF-α to Promote Homing to the Gut and to Improve Acute GvHD Prevention

Antonella Mancusi, PhD, Samanta Bonato, MD, Rachele Del Sordo, MD, Sara Piccinelli, Eni Hoxha, Tiziana Zei, Roberta Iacucci Ostini, Franca Falzetti, MD, Alessandra Carotti, MD, Loredana Ruggeri, MD, Michele Giansanti, MD, Robert S. Negrin, MD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4447.
https://doi.org/10.1182/blood-2019-123202
Published: 2019
Journal Articles

How Adoptive Immunotherapy with Conventional T and Regulatory T Cells Exerts a Gvl Effect without GvHD, after Haploidentical Hematopoietic Transplantation

Loredana Ruggeri, Alessandra Carotti, MD, Antonio Pierini, Franca Falzetti, Adelmo Terenzi, MD, Elena Urbani, Amico Lucia, MD PhD, Sara Tricarico, MD, Sara Piccinelli, MD, Maria Speranza Massei, MD, Sara Ciardelli, Mauro Di Ianni, MD PhD, Tiziana Zei, Roberta Iacucci Ostini, Valentina Lancellotta, MD, Simonetta Saldi, MD, Olivia Minelli, MD, Rita Tognellini, Mara Merluzzi, Mauro Marchesi, MD, Maurizio Caniglia, MD, Cynthia Aristei, MD PhD, Brunangelo Falini, MD PhD, Massimo Fabrizio Martelli, MD PhD, Andrea Velardi
Journal: Blood
Blood (2018) 132 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2018-99-112512
Published: 2018
Journal Articles

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

Clinical Trials & Observations
Massimo F. Martelli, Mauro Di Ianni, Loredana Ruggeri, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Antonio Pierini, Maria Speranza Massei, Lucia Amico, Elena Urbani, Beatrice Del Papa, Tiziana Zei, Roberta Iacucci Ostini, Debora Cecchini, Rita Tognellini, Yair Reisner, Franco Aversa, Brunangelo Falini, Andrea Velardi
Journal: Blood
Blood (2014) 124 (4): 638–644.
https://doi.org/10.1182/blood-2014-03-564401
Published: 2014
Journal Articles

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

Clinical Trials & Observations
Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Flora Castellino, Elisabetta Bonifacio, Beatrice Del Papa, Tiziana Zei, Roberta Iacucci Ostini, Debora Cecchini, Teresa Aloisi, Katia Perruccio, Loredana Ruggeri, Chiara Balucani, Antonio Pierini, Paolo Sportoletti, Cynthia Aristei, Brunangelo Falini, Yair Reisner, Andrea Velardi, Franco Aversa, Massimo F. Martelli
Journal: Blood
Blood (2011) 117 (14): 3921–3928.
https://doi.org/10.1182/blood-2010-10-311894
Published: 2011