1-11 of 11
Robert K. Bradley, PhD
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Coordinated Mis-Splicing of Multiple Mitochondrial Iron Metabolism Genes Causes Ring Sideroblast Formation in SF3B1-Mutant MDS

Courtnee Clough, Joseph Pangallo, PhD, Martina Sarchi, MD, Stephanie Busch, B.S., Janis L. Abkowitz, MD, Robert K. Bradley, PhD, Sergei Doulatov, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4.
https://doi.org/10.1182/blood-2020-140817
Published: 2020
Journal Articles

ZRSR2 Mutation Induced Minor Intron Retention Drives MDS and Diverse Cancer Predisposition Via Aberrant Splicing of LZTR1

Daichi Inoue, MDPhD, Jacob T. Polaski, Justin Taylor, MD, Pau Castel, Sisi Chen, Susumu Kobayashi, Simon J. Hogg, PhD BSc, Yasutaka Hayashi, MDPhD, Jose Mario Bello Pineda, Alexander V Penson, PhD, Ettaib El Marabti, Caroline Erickson, Miki Fukumoto, Hiromi Yamazaki, PhD, Chie Fukui, Sydney X. Lu, MD PhD, Benjamin H. Durham, Bo Liu, PhD, Sanjoy Mehta, Daniel Zakheim, Ralph Garippa, PhD, Guo-Liang Chew, Frank McCormick, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-136445
Published: 2020
Journal Articles

Glucocorticoids Regulate the Splicing Factor MBNL1, a Potential Control Point for B-Cell Specification

Miles A. Pufall, PhD, Mimi Fang, Robert K. Bradley, PhD, Chew Guo-Liang, Ross Lanier, Sarah K. Tasian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2478.
https://doi.org/10.1182/blood-2019-131322
Published: 2019
Journal Articles

Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias

Daichi Inoue, MD PhD, Chew Guo-Liang, Bo Liu, PhD, Stanley C Lee, PhD, Brittany C Michel, Joey Pangallo, B.S., Andrew R D'Avino, Khrystyna North, Lillian E Bitner, BSc, Muran Xiao, Susumu Kobayashi, Akihide Yoshimi, MD PhD, Hana Cho, MSc, Sydney X Lu, MD PhD, Justin Taylor, MD, Cigall Kadoch, PhD, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 637.
https://doi.org/10.1182/blood-2019-124616
Published: 2019
Journal Articles

Probing Aberrant Splicing in a Novel Model of SF3B1-Mutant Myelodysplastic Syndromes

Courtnee Clough, Stephanie Busch, B.S., Joey Pangallo, B.S., Robert K. Bradley, PhD, Sergei Doulatov, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1706.
https://doi.org/10.1182/blood-2019-129176
Published: 2019
Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 937.
https://doi.org/10.1182/blood-2018-99-111552
Published: 2018
Journal Articles

A Chemical Modifier Screen in Zebrafish Mutants for the Spliceosomal Component Sf3b1reveals Genotype-Selective Vulnerabilities

Rosannah C. Cameron, PhD, Mia McKinstry, Adriana De La Garza, Sara Nik, Peter G Smith, PhD, Silvia Buonamici, PhD, Robert K. Bradley, PhD, Teresa V. Bowman, PhD
Journal: Blood
Blood (2016) 128 (22): 965.
https://doi.org/10.1182/blood.V128.22.965.965
Published: 2016
Journal Articles

Therapeutic Targeting of Spliceosomal Mutant Myeloid Leukemias through Modulation of Splicing Catalysis

Stanley Chun-Wei Lee, PhD, Heidi Dvinge, Eunhee Kim, PhD, Hana Cho, Young Rock Chung, MS, Jean-Baptiste Micol, MD, Benjamin Durham, MD PhD, Young Joon Kim, Michael Thomas, Camille Lobry, PhD, Silvia Buonamici, PhD, Peter Smith, Robert K. Bradley, PhD, Omar Abdel-Wahab
Journal: Blood
Blood (2015) 126 (23): 4.
https://doi.org/10.1182/blood.V126.23.4.4
Published: 2015
Journal Articles

SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference

Eunhee Kim, PhD, Janine O. Ilagan, PhD, Stanley Lee, PhD, Aravind Ramakrishnan, MD, Young Rock Chung, MS, Jean-Baptiste Micol, MD, Michele E. Murphy, Min-Kyung Kim, BS, Ahmad S. Zebari, Jacob Feala, Silvia Buonamici, PhD, Peter G Smith, PhD, H. Joachim Deeg, MD, Camille Lobry, PhD, Iannis Aifantis, PhD MSC, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 824.
https://doi.org/10.1182/blood.V124.21.824.824
Published: 2014
Journal Articles

Sample Processing Obscures Cancer-Specific Alterations in Leukemic Transcriptomes

Heidi Dvinge, PhD, Rhonda E. Ries, MA, Janine O. Ilagan, PhD, Derek L. Stirewalt, MD, Soheil Meshinchi, MD PhD, Robert K. Bradley, PhD
Journal: Blood
Blood (2014) 124 (21): 2201.
https://doi.org/10.1182/blood.V124.21.2201.2201
Published: 2014
Journal Articles

U2AF1 Mutations Cause Allele-Specific Alterations in 3' Splice Site Recognition in Myeloid Malignancies

Janine O. Ilagan, PhD, Aravind Ramakrishnan, MD, Brian Hayes, PhD, Michele E. Murphy, Ahmad S. Zebari, Philip Bradley, PhD, Robert K. Bradley, PhD
Journal: Blood
Blood (2014) 124 (21): 1889.
https://doi.org/10.1182/blood.V124.21.1889.1889
Published: 2014