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Rachel Courtney
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Journal Articles

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

Clinical Trials & Observations
John P. Leonard, Ann S. LaCasce, Mitchell R. Smith, Ariela Noy, Lucian R. Chirieac, Scott J. Rodig, Jian Q. Yu, Shankar Vallabhajosula, Heiko Schoder, Patricia English, Donna S. Neuberg, Peter Martin, Michael M. Millenson, Scott A. Ely, Rachel Courtney, Naveed Shaik, Keith D. Wilner, Sophia Randolph, Annick D. Van den Abbeele, Selina Y. Chen-Kiang, Jeffrey T. Yap, Geoffrey I. Shapiro
Journal: Blood
Blood (2012) 119 (20): 4597–4607.
https://doi.org/10.1182/blood-2011-10-388298
Published: 2012
Includes: Supplemental data
Journal Articles

PF-04449913 Reverts Multi Drug Resistance (MDR) by a Strong Down-Regulation of ABCA2 and BCL2 on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Cristina Papayannidis, Viviana Guadagnuolo, Ilaria Iacobucci, PhD, Sandra Durante, Carolina Terragna, PhD, Emanuela Ottaviani, Maria Chiara Abbenante, Federica Cattina, MD, Simona Soverini, Barbara Lama, Lucia Toni, Wendy J. Levin, MD, MS, Rachel Courtney, PhD, Carmen Baldazzi, Antonio Curti, MD, Michele Baccarani, MD, Catriona Jamieson, Jorge E. Cortes, Vivian Oehler, MD, Karen McLachlan, Todd Van Arsdale, PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 1429.
https://doi.org/10.1182/blood.V118.21.1429.1429
Published: 2011
Journal Articles

Phase 1 Dose-Escalation Study of PF-04449913, An Oral Hedgehog (Hh) Inhibitor, in Patients with Select Hematologic Malignancies

Catriona Jamieson, Jorge E. Cortes, Vivian Oehler, MD, Michele Baccarani, MD, Hagop M. Kantarjian, Cristina Papayannidis, Kristen N. Rice, MD, Xiaoxi Zhang, Naveed Shaik, Rachel Courtney, PhD, Wendy J. Levin, MD, MS, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 424.
https://doi.org/10.1182/blood.V118.21.424.424
Published: 2011
Journal Articles

Gas1 and Kif27 Genes Are Strongly up-Regulated Biomarkers of Hedgehog Inhibition (PF-04449913) on Leukemia Stem Cells in Phase I Acute Myeloid Leukemia and Chronic Myeloid Leukemia Treated Patients

Viviana Guadagnuolo, Cristina Papayannidis, Ilaria Iacobucci, PhD, Sandra Durante, Carolina Terragna, PhD, Emanuela Ottaviani, Maria Chiara Abbenante, Federica Cattina, MD, Simona Soverini, Barbara Lama, Lucia Toni, Wendy J. Levin, MD, MS, Rachel Courtney, PhD, Carmen Baldazzi, Antonio Curti, MD, Michele Baccarani, MD, Catriona Jamieson, MD, Ph.D., Jorge E. Cortes, Vivian Oehler, MD, Karen McLachlan, Todd Van Arsdale, PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2011) 118 (21): 1535.
https://doi.org/10.1182/blood.V118.21.1535.1535
Published: 2011
Journal Articles

A Phase I Study of PD 0332991: Complete CDK4/6 Inhibition and Tumor Response In Sequential Combination with Bortezomib and Dexamethasone for Relapsed and Refractory Multiple Myeloma

Ruben Niesvizky, MD, Suzanne Lentzsch, MD, PhD, Ashraf Z. Badros, MD, Asher A. Chanan-Khan, MD, Seema B. Singhal, MD, Jeffrey A. Zonder, MD, Ravi Vij, MBBS, MD, Xiangao Huang, PhD, Maurizio DiLiberto, PhD, Rachel Courtney, PhD, M. Naveed Shaik, PhD, Sindy T. Kim, BS, Sophia Randolph, MD, PhD, Scott A Ely, MD, MPH, Selina Chen-Kiang, PhD
Journal: Blood
Blood (2010) 116 (21): 860.
https://doi.org/10.1182/blood.V116.21.860.860
Published: 2010
Journal Articles

A Phase I Trial of PD 0332991, a Novel, Orally-Bioavailable CDK4/6-Specific Inhibitor Administered in Combination with Bortezomib and Dexamethasone to Patients with Relapsed and Refractory Multiple Myeloma.

Ruben Niesvizky, MD, Scott Ely, MD, MPH, David S Jayabalan, Megan C. Manco, Seema Singhal, MD, Mary Crann, Rachel Courtney, Cynthia DuFresne, Keith D. Wilner, PhD, Isan Chen, MD, Tomer Mark, MD, John P. Leonard, MD, Morton Coleman, MD, Maurizio DiLiberto, PhD, Xiangao Huang, PhD, Selina Chen-Kiang, PhD
Journal: Blood
Blood (2009) 114 (22): 1877.
https://doi.org/10.1182/blood.V114.22.1877.1877
Published: 2009