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Journal Articles

Immunomodulatory Microbial Metabolites Protect Against Graft-Vs-Host Disease and Enhance Anti-Leukemia Responses in Mice and Patients Receiving Stem Cell Transplantation

Sascha Göttert, Erik Thiele-Orberg, Kaiji Fan, Paul Heinrich, Daniel Wolff, Daniela Weber, Florian Bassermann, Petra Hoffmann, Matthias Edinger, Natalie Koehler, André Gessner, Wolfgang Herr, Simon M Heidegger, Ernst Holler, Hendrik Poeck

Blood (2024) 144 (Supplement 1): 264.

https://doi.org/10.1182/blood-2024-205921

Published: 2024

Journal Articles

Expansion of Plasmablasts at Day 90 after Allogeneic Stem Cell Transplantation Predict Chronic Gvhd

Katharina M. Habenicht, Anna Bootz, Simon Schäfer, Ingrid Vasova, Matthias Fante, Andrea Schneider, Michael Rehli, Petra Hoffmann, Wolf Roesler, Matthias Edinger, Wolfgang Herr, Andreas Mackensen, Daniel Wolff, Julia Winkler, Thomas H. Winkler

Blood (2022) 140 (Supplement 1): 4776–4777.

https://doi.org/10.1182/blood-2022-165915

Published: 2022

Journal Articles

Stem Cell Transplantation in Advanced Stage Sickle Cell Disease with Haploidentical T-Cell Depleted PBSC Yields Comparable Outcomes to Matched Sibling Donor Bone Marrow: Results of a Pilot Study

Juergen Foell, MD, Johannes Schulte, Anja Troeger, MD, Beatrix Pfirstinger, MD, Daniel Wolff, MD, Matthias Edinger, MD PhD, Ernst Holler, MD, Petra Hoffmann, PhD, Charalampos Aslanidis, PhD, Wolfgang Herr, MD, Angelika Eggert, MD PhD, Selim Corbacioglu, MD

Blood (2018) 132 (Supplement 1): 3455.

https://doi.org/10.1182/blood-2018-99-114695

Published: 2018

Journal Articles

Comparable Outcome of CD3+-/CD19+ Depleted Haploidentical with Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Advanced Stage Sickle Cell Disease: Result of a Pilot Study

Selim Corbacioglu, MD PhD, Juergen Foell, MD, Daniel Wolff, MD, Ernst Holler, MD, Beatrix Pfirstinger, MD, Klaus Thorsten Rehe, MD, Petra Hoffmann, PhD, Matthias Edinger, MD, Anja Troeger, MD, Svatava Srutkova, MD

Blood (2017) 130 (Supplement 1): 4594.

https://doi.org/10.1182/blood.V130.Suppl_1.4594.4594

Published: 2017

Journal Articles

The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations

Christian Schmidl, Leo Hansmann, Timo Lassmann, Piotr J. Balwierz, Hideya Kawaji, Masayoshi Itoh, Jun Kawai, Sayaka Nagao-Sato, Harukazu Suzuki, Reinhard Andreesen, Yoshihide Hayashizaki, Alistair R. R. Forrest, Piero Carninci, Petra Hoffmann, Matthias Edinger, Michael Rehli

Blood (2014) 123 (17): e68–e78.

https://doi.org/10.1182/blood-2013-02-486944

Published: 2014

Includes: Supplemental data

Journal Articles

Transcription and enhancer profiling in human monocyte subsets

Christian Schmidl, Kathrin Renner, Katrin Peter, Ruediger Eder, Timo Lassmann, Piotr J. Balwierz, Masayoshi Itoh, Sayaka Nagao-Sato, Hideya Kawaji, Piero Carninci, Harukazu Suzuki, Yoshihide Hayashizaki, Reinhard Andreesen, David A. Hume, Petra Hoffmann, Alistair R. R. Forrest, Marina P. Kreutz, Matthias Edinger, Michael Rehli

Blood (2014) 123 (17): e90–e99.

https://doi.org/10.1182/blood-2013-02-484188

Published: 2014

Includes: Supplemental data

Journal Articles

Regulatory T Cells Preserve Anti-Viral Immunity While Preventing Lethal Graft-Versus-Host Disease

Thomas H. Winkler, PhD, Martina Seefried, Irena Kroeger, Petra Hoffmann, PhD, Matthias Edinger, Evelyn Ullrich, Michael Mach

Blood (2013) 122 (21): 5432.

https://doi.org/10.1182/blood.V122.21.5432.5432

Published: 2013

Journal Articles

Graft-Versus-Host Disease Impairs Early B Lymphopoiesis in the Bone Marrow

Kristina Doser, PhD, Tina J Boeld, PhD, Martin Heidenreich, Reinhard Andreesen, MD, PhD, Petra Hoffmann, PhD, Matthias Edinger, MD

Blood (2011) 118 (21): 2976.

https://doi.org/10.1182/blood.V118.21.2976.2976

Published: 2011

Journal Articles

Increased Susceptibility to Fungal Infection in Recipients with GVHD Is Not Due to Impaired Pathogen Clearance and Can Be Prevented by Co-Transfer of Donor CD4 + CD25 + Regulatory T Cells

Petra Hoffmann, PhD, Kristina Doser, PhD, Matthias Edinger, MD, Bernd Echtenacher, PhD

Blood (2011) 118 (21): 822.

https://doi.org/10.1182/blood.V118.21.822.822

Published: 2011

Journal Articles

Efficient Treatment of Murine Acute Graft-Versus-Host Disease with In Vitro Expanded CD4 + CD25 + Regulatory T Cells

Tina J Boeld, PhD, Kristina Doser, PhD, Corinna Lang-Schwarz, MD, Elisabeth Huber, MD, Reinhard Andreesen, MD, PhD, Petra Hoffmann, PhD, Matthias Edinger, MD

Blood (2011) 118 (21): 2987.

https://doi.org/10.1182/blood.V118.21.2987.2987

Published: 2011

Journal Articles

Lymphocyte Subsets In Chronic Gvhd – a Key Role for B Cells?

Inken Hilgendorf, Brigitte Mueller-Hilke, Guenther Kundt, Ernst Holler, Petra Hoffmann, Mathias Edinger, Mathias Freund, Daniel Wolff

Blood (2010) 116 (21): 2311.

https://doi.org/10.1182/blood.V116.21.2311.2311

Published: 2010

Journal Articles

Delayed Onset of T Cell-Mediated Xenogeneic Disease in Rag2 −/− γ c −/− mice after Co- Transplantation of in Vitro Expanded Human CD4 + CD25 high CD45RA + Regulatory T Cells

Tina J Boeld, Ellen Obermann, Reinhard Andreesen, Petra Hoffmann, Matthias Edinger, MD

Blood (2008) 112 (11): 4609.

https://doi.org/10.1182/blood.V112.11.4609.4609

Published: 2008

Journal Articles

Only MHC-Identical Donor CD4 + CD25 + Regulatory T Cells Convey Full Protection from Lethal Graft-Versus-Host Disease

Julia Albrecht, Kristina Doser, Reinhard Andreesen, Joerg Ermann, Matthias Edinger, Petra Hoffmann

Blood (2008) 112 (11): 3516.

https://doi.org/10.1182/blood.V112.11.3516.3516

Published: 2008

Journal Articles

Loss of FOXP3 Expression and Emergence of Cytokine-Producing Cells after In Vitro Expansion of Human CD4+CD25+CD127 - Regulatory T Cells.

Petra Hoffmann, PhD, Ruediger Eder, Tina J. Boeld, Jochen Huehn, PhD, Stefan Floess, PhD, Georg Wieczorek, PhD, Udo Baron, PhD, Sven Olek, PhD, Reinhard Andreesen, MD, Matthias Edinger, MD

Blood (2007) 110 (11): 63.

https://doi.org/10.1182/blood.V110.11.63.63

Published: 2007

Journal Articles

Inhibitory effect of tumor cell–derived lactic acid on human T cells

Karin Fischer, Petra Hoffmann, Simon Voelkl, Norbert Meidenbauer, Julia Ammer, Matthias Edinger, Eva Gottfried, Sabine Schwarz, Gregor Rothe, Sabine Hoves, Kathrin Renner, Birgit Timischl, Andreas Mackensen, Leoni Kunz-Schughart, Reinhard Andreesen, Stefan W. Krause, Marina Kreutz

Blood (2007) 109 (9): 3812–3819.

https://doi.org/10.1182/blood-2006-07-035972

Published: 2007

Includes: Supplemental data

Journal Articles

Only the CD45RA + subpopulation of CD4 + CD25 high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

Petra Hoffmann, Ruediger Eder, Tina J. Boeld, Kristina Doser, Biserka Piseshka, Reinhard Andreesen, Matthias Edinger

Blood (2006) 108 (13): 4260–4267.

https://doi.org/10.1182/blood-2006-06-027409

Published: 2006

Journal Articles

Low-Dose Cyclosporin A Does Not Abrogate the Suppressive Function of In Vitro Expanded Human CD4 + CD25 + Regulatory T Cells.

Biserka Piseshka, Ruediger Eder, Tina J. Boeld, Reinhard Andreesen, MD, Ernst Holler, MD, Petra Hoffmann, PhD, Matthias Edinger, MD

Blood (2006) 108 (11): 5170.

https://doi.org/10.1182/blood.V108.11.5170.5170

Published: 2006

Journal Articles

Only Naive CD45RA + CD4 + CD25 high T Cells from Human Peripheral Blood Give Rise to Homogeneous Regulatory T Cell Lines.

Petra Hoffmann, PhD, Ruediger Eder, Tina J. Boeld, Kristina Doser, Biserka Piseshka, Reinhard Andreesen, MD, Matthias Edinger, MD

Blood (2006) 108 (11): 3163.

https://doi.org/10.1182/blood.V108.11.3163.3163

Published: 2006

Journal Articles

Only the CD62L + subpopulation of CD4 + CD25 + regulatory T cells protects from lethal acute GVHD

Joerg Ermann, Petra Hoffmann, Matthias Edinger, Suparna Dutt, Francis G. Blankenberg, John P. Higgins, Robert S. Negrin, C. Garrison Fathman, Samuel Strober

Blood (2005) 105 (5): 2220–2226.

https://doi.org/10.1182/blood-2004-05-2044

Published: 2005

Journal Articles

Isolation of Human CD4 + CD25 + T Cells with Regulatory Capacity for Clinical Trials.

Petra Hoffmann, PhD, Ruediger Eder, Biserka Piseshka, Andrea Havasi, Evelyn Orso, MD, Ashraf Dada, MD, Reinhard Andreesen, MD, Ernst Holler, MD, Matthias Edinger, MD

Blood (2004) 104 (11): 2851.

https://doi.org/10.1182/blood.V104.11.2851.2851

Published: 2004

NARROW

Immunomodulatory Microbial Metabolites Protect Against Graft-Vs-Host Disease and Enhance Anti-Leukemia Responses in Mice and Patients Receiving Stem Cell Transplantation

Expansion of Plasmablasts at Day 90 after Allogeneic Stem Cell Transplantation Predict Chronic Gvhd

Stem Cell Transplantation in Advanced Stage Sickle Cell Disease with Haploidentical T-Cell Depleted PBSC Yields Comparable Outcomes to Matched Sibling Donor Bone Marrow: Results of a Pilot Study

Comparable Outcome of CD3+-/CD19+ Depleted Haploidentical with Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Advanced Stage Sickle Cell Disease: Result of a Pilot Study

The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations

Transcription and enhancer profiling in human monocyte subsets

Regulatory T Cells Preserve Anti-Viral Immunity While Preventing Lethal Graft-Versus-Host Disease

Graft-Versus-Host Disease Impairs Early B Lymphopoiesis in the Bone Marrow

Increased Susceptibility to Fungal Infection in Recipients with GVHD Is Not Due to Impaired Pathogen Clearance and Can Be Prevented by Co-Transfer of Donor CD4 + CD25 + Regulatory T Cells

Efficient Treatment of Murine Acute Graft-Versus-Host Disease with In Vitro Expanded CD4 + CD25 + Regulatory T Cells

Lymphocyte Subsets In Chronic Gvhd – a Key Role for B Cells?

Delayed Onset of T Cell-Mediated Xenogeneic Disease in Rag2 −/− γ c −/− mice after Co- Transplantation of in Vitro Expanded Human CD4 + CD25 high CD45RA + Regulatory T Cells

Only MHC-Identical Donor CD4 + CD25 + Regulatory T Cells Convey Full Protection from Lethal Graft-Versus-Host Disease

Loss of FOXP3 Expression and Emergence of Cytokine-Producing Cells after In Vitro Expansion of Human CD4+CD25+CD127 - Regulatory T Cells.

Inhibitory effect of tumor cell–derived lactic acid on human T cells

Only the CD45RA + subpopulation of CD4 + CD25 high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

Low-Dose Cyclosporin A Does Not Abrogate the Suppressive Function of In Vitro Expanded Human CD4 + CD25 + Regulatory T Cells.

Only Naive CD45RA + CD4 + CD25 high T Cells from Human Peripheral Blood Give Rise to Homogeneous Regulatory T Cell Lines.

Only the CD62L + subpopulation of CD4 + CD25 + regulatory T cells protects from lethal acute GVHD

Isolation of Human CD4 + CD25 + T Cells with Regulatory Capacity for Clinical Trials.

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American Society of Hematology

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American Society of Hematology

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