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Journal Articles

The Novel Tyrosine Kinase Inhibitor (TKI) Exel-0862 Potently Induces Apoptosis in Human FIP1L1-PDGFR-α-Expressing Cells through Caspase-Dependent Cleavage of MCL-1.

Jingpan Pan, MD, PhD, Alfonso Quintas-Cardama, M.D., Hagop Kantarjian, M.D., Peter Lamb, Ayalew Tefferi, Jorge Cortes, M.D., Francis Giles, M.D., Srdan Verstovsek, M.D.;PhD

Blood (2006) 108 (11): 4882.

https://doi.org/10.1182/blood.V108.11.4882.4882

Published: 2006

Journal Articles

EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation

Jingxuan Pan, Alfonso Quintás-Cardama, Hagop M. Kantarjian, Cem Akin, Taghi Manshouri, Peter Lamb, Jorge E. Cortes, Ayalew Tefferi, Francis J. Giles, Srdan Verstovsek

Blood (2006) 109 (1): 315–322.

https://doi.org/10.1182/blood-2006-04-013805

Published: 2006

Journal Articles

Species Specificity and Receptor Domain Interaction of a Small Molecule TPO Receptor Agonist.

Connie L. Erickson-Miller, PhD, Evelyn Delorme, PHD, Maya Iskander, Leslie Giampa, Christpher B. Hopson, Juan Luengo, PhD, Kevin Duffy, PhD, Susan B. Dillon, PhD, Jon Rosen, PhD, Stephen Miller, PhD, Peter Lamb, PhD, Shin-Shay Tian, PhD

Blood (2004) 104 (11): 2909.

https://doi.org/10.1182/blood.V104.11.2909.2909

Published: 2004

Journal Articles

Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia.

Juan I. Luengo, Kevin J. Duffy, Anthony N. Shaw, Evelyne Delorme, Kenneth J. Wiggall, Leslie Giampa, Nannan Liu, Heather Smith, Shin-Shay Tian, Stephen G. Miller, Richard M. Keenan, Jon Rosen, Susan B. Dillon, Peter Lamb, Connie L. Erickson-Miller

Blood (2004) 104 (11): 2910.

https://doi.org/10.1182/blood.V104.11.2910.2910

Published: 2004

Journal Articles

Biological Activity and Selectivity for Tpo Receptor of the Orally Bioavailable, Small Molecule Tpo Receptor Agonist, SB-497115.

Connie Erickson-Miller, Evelyn Delorme, Leslie Giampa, Christopher Hopson, Elizabeth Valoret, Shin-Shay Tian, Stephen G. Miller, Richard Keenan, Jon Rosen, Susan Dillon, Kevin Duffy, Peter Lamb, Juan Luengo

Blood (2004) 104 (11): 2912.

https://doi.org/10.1182/blood.V104.11.2912.2912

Published: 2004

NARROW

The Novel Tyrosine Kinase Inhibitor (TKI) Exel-0862 Potently Induces Apoptosis in Human FIP1L1-PDGFR-α-Expressing Cells through Caspase-Dependent Cleavage of MCL-1.

EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation

Species Specificity and Receptor Domain Interaction of a Small Molecule TPO Receptor Agonist.

Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia.

Biological Activity and Selectivity for Tpo Receptor of the Orally Bioavailable, Small Molecule Tpo Receptor Agonist, SB-497115.

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ASH Publications

American Society of Hematology

The Novel Tyrosine Kinase Inhibitor (TKI) Exel-0862 Potently Induces Apoptosis in Human FIP1L1-PDGFR-α-Expressing Cells through Caspase-Dependent Cleavage of MCL-1.

EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation

Species Specificity and Receptor Domain Interaction of a Small Molecule TPO Receptor Agonist.

Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia.

Biological Activity and Selectivity for Tpo Receptor of the Orally Bioavailable, Small Molecule Tpo Receptor Agonist, SB-497115.

Email alerts

ASH Publications

American Society of Hematology

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