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Journal Articles

Effect of the Neddylation Inhibitor Pevonedistat on Normal Hematopoietic Stem Cell Subsets and Immune Cell Composition

Fatemeh Majidi, Oumaima Stambouli, Ron-Patrick Cadeddu, Simon Kai Brille, Jasmin Ewert, Ulrich Germing, Robert Zeiser, Bernd Giebel, Norbert Gattermann

Blood (2021) 138 (Supplement 1): 4787.

https://doi.org/10.1182/blood-2021-150095

Published: 2021

Journal Articles

Impaired Formation of Neutrophil Extracellular Traps (NETs) in Patients with Myelodysplastic Syndrome (MDS)

Carolin Brings, Ron-Patrick Cadeddu, PhD, Julia Fröbel, PhD, Hubert Schelzig, MD, Rainer Haas, MD, Norbert Gattermann, MD

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-138409

Published: 2020

Journal Articles

Altered Expression of Neddylation Pathway Proteins in Myelodysplastic Syndromes

Fatemeh Majidi, MD, Judith Neukirchen, MD, Simon Brille, Iris Fey, BSc., Frank Neumann, MDPhD, Allison Berger, PhD, Ron-Patrick Cadeddu, PhD, Martina Rudelius, MD, Ulrich Germing, MD, Rainer Haas, MD, Norbert Gattermann, MD

Blood (2017) 130 (Supplement 1): 5298.

https://doi.org/10.1182/blood.V130.Suppl_1.5298.5298

Published: 2017

Journal Articles

Concordant Underexpression of Fanconi Anemia/BRCA1 Pathway Proteins in a Major Proportion of Myelodysplastic Syndromes

Fatemeh Majidi, MD, Judith Neukirchen, MD, Ulrich Germing, M. D., Ron-Patrick Cadeddu, Stefan Braunstein, MD, Rainer Haas, MD, Norbert Gattermann, MD

Blood (2016) 128 (22): 4311.

https://doi.org/10.1182/blood.V128.22.4311.4311

Published: 2016

Journal Articles

Functional Inhibition of Mesenchymal Stem and Progenitor Cells (MSPC) Significantly Contributes to Hematopoietic Insufficiency with Acute Myeloid Leukemia (AML)

Stefanie Geyh, Manuel Rodríguez-Paredes, Cyrus Khandanpour, MD, Ron-Patrick Cadeddu, Paul Jäger, Christoph Zilkens, Ulrich Dührsen, MD, C. Matthias Wilk, Roland Fenk, MD, Norbert Gattermann, MD PhD, Ulrich Germing, Guido Kobbe, MD, Frank Lyko, PhD, Rainer Haas, MD, Thomas Schroeder, MD

Blood (2014) 124 (21): 3492.

https://doi.org/10.1182/blood.V124.21.3492.3492

Published: 2014

Journal Articles

Salvage Therapy with Azacitidine Increases Regulatory T Cells in Patients with AML or MDS and Early Relapse After Allogeneic Blood Stem Cell Transplantation

Thomas Schroeder, MD, Julia Fröbel, Ron Patrick Cadeddu, Akos G. Czibere, MD, Ariane Dienst, Esther Zipperer, MD, Uwe Platzbecker, MD, Gesine Bug, Lutz Uharek, MD, Roland Fenk, MD, Ulrich Germing, Nicolaus Kröger, Rainer Haas, MD, Guido Kobbe, MD

Blood (2012) 120 (21): 1964.

https://doi.org/10.1182/blood.V120.21.1964.1964

Published: 2012

Journal Articles

Multiple myeloma–related deregulation of bone marrow–derived CD34 + hematopoietic stem and progenitor cells

Blood (2012) 120 (13): 2620–2630.

https://doi.org/10.1182/blood-2011-04-347484

Published: 2012

Includes: Supplemental data

Journal Articles

Analysis of Mesenchymal Stromal Cells (MSC) and Their Interactions with CD34 Stem and Progenitor Cells in Patients with Myelodysplastic Syndromes (MDS)

Stefanie Geyh, Ron Patrick Cadeddu, Julia Fröbel, Ingmar Bruns, MD, Fabian Zohren, Ali-Nuri Hünerlitürkoglu, Guido Kobbe, MD, Norbert Gattermann, MD, Ulrich Germing, MD, Rainer Haas, Thomas Schroeder, MD

Blood (2011) 118 (21): 2393.

https://doi.org/10.1182/blood.V118.21.2393.2393

Published: 2011

Journal Articles

The Disease-Related Bone Marrow Microenvironment Alters Hematopoietic Stem and Progenitor Function in Multiple Myeloma Patients

Ingmar Bruns, MD, Ron-Patrick Cadeddu, Ines Brückmann, Sebastian Buest, Julia Fröbel, Thomas Schroeder, Stefanie Geyh, Ali-Nuri Hünerlitürkoglu, Guido Kobbe, MD, Roland Fenk, Andreas Trumpp, Akos Czibere, MD, PhD, Rainer Haas

Blood (2011) 118 (21): 2898.

https://doi.org/10.1182/blood.V118.21.2898.2898

Published: 2011

Journal Articles

Natalizumab Increases Circulating CD34+ Cells with An Impaired Functional Potential In Patients with Multiple Sclerosis without Affecting the Bone Marrow.

Christian Saure, MD, Fabian Zohren, MD, Thomas Schroeder, MD, Ingmar Bruns, MD, Ron Patrick Cadeddu, Ute Fischer, MD, Guido Kobbe, MD, Hans Peter Hartung, Bernd C Kieseier, Rainer Haas

Blood (2010) 116 (21): 2620.

https://doi.org/10.1182/blood.V116.21.2620.2620

Published: 2010

Journal Articles

TIMP–1 Plays a Functional Role in CD34. + Hematopoietic Stem and Progenitor Cells.

C. Matthias Wilk, Akos G. Czibere, MD, PhD, Ron-Patrick Cadeddu, Sebastian Buest, Frank A. Schildberg, Marcel A. Lauterbach, Volker Westphal, PhD, Stefan W. Hell, Prof., Rainer Haas, Prof., Ingmar Bruns, MD, PhD

Blood (2009) 114 (22): 1487.

https://doi.org/10.1182/blood.V114.22.1487.1487

Published: 2009

Journal Articles

Malignant Myeloma Cells Impair Phenotype and Function of stem and Progenitor Cells.

Ingmar Bruns, MD, PhD, Sebastian Büst, Akos G. Czibere, MD, Ron-Patrick Cadeddu, Ines Brückmann, Manoj Bhasin, Johannes C Fischer, Roland Fenk, Guido Kobbe, MD, Andreas Trumpp, Rainer Haas

Blood (2009) 114 (22): 1799.

https://doi.org/10.1182/blood.V114.22.1799.1799

Published: 2009

Journal Articles

Neuropeptides Orexin A and B Are Funktionally Aktive in CD34+ Hematopoietic Stem and Progenitor Cells.

Ron-Patrick Cadeddu, Akos G. Czibere, MD, Sebastian Büst, Johannes C Fischer, Ulrich Steidl, MD, PhD, Ralf Kronenwett, Guido Kobbe, MD, Rainer Haas, Ingmar Bruns, MD, PhD

Blood (2009) 114 (22): 4593.

https://doi.org/10.1182/blood.V114.22.4593.4593

Published: 2009

Journal Articles

Platelets Derived From Patients with Myelodysplastic Syndromes (MDS) Show Defective Platelet Aggregation and Integrin aIIbβ3 Receptor (GPIIb/IIIa) Signaling Caused by a Reduced Expression of Proteins Required for Inside-out Signaling.

Akos G. Czibere, MD, Julia Fröbel, Sonja Hartwig, Ron-Patrick Cadeddu, Matthias Wilk, Ingmar Bruns, MD, PhD, Sebastian Büst, Guido Kobbe, MD, Andrea Kündgen, Jürgen Eckel, Stefan Lehr, Rainer Haas

Blood (2009) 114 (22): 598.

https://doi.org/10.1182/blood.V114.22.598.598

Published: 2009

Journal Articles

The Neuropeptides Orexin a and B Have An Impact on Functional Properties of Human CD34+ Stem and Progenitor Cells.

Ingmar Bruns, MD, PhD, Patrick Cadeddu, Sebastian Büst, Boris Goerg, Johannes C Fischer, Oliver Selbach, Ulrich Steidl, MD, PhD, Ralf Kronenwett, Rainer Haas, Guido Kobbe, Akos Czibere, MD, PhD

Blood (2008) 112 (11): 1393.

https://doi.org/10.1182/blood.V112.11.1393.1393

Published: 2008

Journal Articles

Hematopoiesis in Chronic Phase CML emerges from Hematopoietic Stem Cells with a Transcriptional Phenotype Resembling Normal Myeloid Progenitor Cells.

Ingmar Bruns, MD, PhD, Akos Czibere, MD, PhD, Patrick Cadeddu, Frederik Roels, Johannes C Fischer, Sebastian Büst, Daniela Brünnert, Ulrich Steidl, MD, PhD, Benedict Brors, Norbert Gattermann, MD, Ralf Kronenwett, Rainer Haas

Blood (2008) 112 (11): 3365.

https://doi.org/10.1182/blood.V112.11.3365.3365

Published: 2008

Journal Articles

Molecular Signature of Distinct CD34+ Hematopoietic Stem and Progenitor Cell Subsets of Patients with CML in Chronic Phase.

Ingmar Bruns, MD, Akos G. Czibere, MD, Johannes C. Fischer, MD, Ulrich Steidl, MD, PhD, Sabrina Pechtel, Annemarie Koch, Daniela Brünnert, Sebastian Büst, Ron-Patrick Cadeddu, Ralf Kronenwett, MD, Rainer Haas, MD

Blood (2007) 110 (11): 3170.

https://doi.org/10.1182/blood.V110.11.3170.3170

Published: 2007

NARROW

Effect of the Neddylation Inhibitor Pevonedistat on Normal Hematopoietic Stem Cell Subsets and Immune Cell Composition

Impaired Formation of Neutrophil Extracellular Traps (NETs) in Patients with Myelodysplastic Syndrome (MDS)

Altered Expression of Neddylation Pathway Proteins in Myelodysplastic Syndromes

Concordant Underexpression of Fanconi Anemia/BRCA1 Pathway Proteins in a Major Proportion of Myelodysplastic Syndromes

Functional Inhibition of Mesenchymal Stem and Progenitor Cells (MSPC) Significantly Contributes to Hematopoietic Insufficiency with Acute Myeloid Leukemia (AML)

Salvage Therapy with Azacitidine Increases Regulatory T Cells in Patients with AML or MDS and Early Relapse After Allogeneic Blood Stem Cell Transplantation

Multiple myeloma–related deregulation of bone marrow–derived CD34 + hematopoietic stem and progenitor cells

Analysis of Mesenchymal Stromal Cells (MSC) and Their Interactions with CD34 Stem and Progenitor Cells in Patients with Myelodysplastic Syndromes (MDS)

The Disease-Related Bone Marrow Microenvironment Alters Hematopoietic Stem and Progenitor Function in Multiple Myeloma Patients

Natalizumab Increases Circulating CD34+ Cells with An Impaired Functional Potential In Patients with Multiple Sclerosis without Affecting the Bone Marrow.

TIMP–1 Plays a Functional Role in CD34. + Hematopoietic Stem and Progenitor Cells.

Malignant Myeloma Cells Impair Phenotype and Function of stem and Progenitor Cells.

Neuropeptides Orexin A and B Are Funktionally Aktive in CD34+ Hematopoietic Stem and Progenitor Cells.

Platelets Derived From Patients with Myelodysplastic Syndromes (MDS) Show Defective Platelet Aggregation and Integrin aIIbβ3 Receptor (GPIIb/IIIa) Signaling Caused by a Reduced Expression of Proteins Required for Inside-out Signaling.

The Neuropeptides Orexin a and B Have An Impact on Functional Properties of Human CD34+ Stem and Progenitor Cells.

Hematopoiesis in Chronic Phase CML emerges from Hematopoietic Stem Cells with a Transcriptional Phenotype Resembling Normal Myeloid Progenitor Cells.

Molecular Signature of Distinct CD34+ Hematopoietic Stem and Progenitor Cell Subsets of Patients with CML in Chronic Phase.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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