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Journal Articles

Gasdermin D drives focal Crystalline Thrombotic Microangiopathy by accelerating Immunothrombosis and Necroinflammation

Kanako Watanabe-Kusunoki, Chenyu Li, Tâmisa Seeko Bandeira Honda, Danyang Zhao, Yoshihiro Kusunoki, John Ku, Hao Long, Martin Klaus, Chao Han, Attila Braun, Elmina Mammadova-Bach, Andreas Linkermann, Kristof Van Avondt, Mathis Richter, Oliver Soehnlein, Monika I. Linder, Christoph Klein, Stefanie Steiger, Hans-Joachim Anders
Journal: Blood
Blood blood.2023021949.
https://doi.org/10.1182/blood.2023021949
Published: 2024
Includes: Supplemental data
Journal Articles

CRISPR/Cas9 Strategy for Correcting ELANE Mutations and Restoring Neutrophil Differentiation in Severe Congenital Neutropenia: Insights from Patient-Derived iPSCs

Zuzanna Rydzynska, Dawid Grzela, Monika I Linder, Weronika Dobrewa, Zuzanna Urbanska, Bartlomiej Pawlik, Damian Krzyzanowski, Maciej Mazurek, Szymon Janczar, Joanna Madzio, Wojciech Mlynarski
Journal: Blood
Blood (2023) 142 (Supplement 1): 4100.
https://doi.org/10.1182/blood-2023-188759
Published: 2023
Journal Articles

Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes

Monika I. Linder, Yoko Mizoguchi, Sebastian Hesse, Gergely Csaba, Megumi Tatematsu, Marcin Łyszkiewicz, Natalia Ziȩtara, Tim Jeske, Maximilian Hastreiter, Meino Rohlfs, Yanshan Liu, Piotr Grabowski, Kaarin Ahomaa, Daniela Maier-Begandt, Marko Schwestka, Vahid Pazhakh, Abdulsalam I. Isiaku, Brenda Briones Miranda, Piers Blombery, Megumu K. Saito, Ejona Rusha, Zahra Alizadeh, Zahra Pourpak, Masao Kobayashi, Nima Rezaei, Ekrem Unal, Fabian Hauck, Micha Drukker, Barbara Walzog, Juri Rappsilber, Ralf Zimmer, Graham J. Lieschke, Christoph Klein
Journal: Blood
Blood (2023) 141 (6): 645–658.
https://doi.org/10.1182/blood.2022016783
Published: 2023
Includes: Supplemental data
Journal Articles

Induced Pluripotent Stem Cell-Derived Neutrophil Granulocytes - Flow Cytometry Analysis Reveals Distinct Subpopulations

Stephanie Frenz, Raffaele Conca, Sebastian Hesse, Monika I. Linder, Christoph Klein
Journal: Blood
Blood (2021) 138 (Supplement 1): 3126.
https://doi.org/10.1182/blood-2021-150495
Published: 2021
Journal Articles

Mammalian VPS45 orchestrates trafficking through the endosomal system

Laura Frey, Natalia Ziętara, Marcin Łyszkiewicz, Benjamin Marquardt, Yoko Mizoguchi, Monika I. Linder, Yanshan Liu, Florian Giesert, Wolfgang Wurst, Maik Dahlhoff, Marlon R. Schneider, Eckhard Wolf, Raz Somech, Christoph Klein
Journal: Blood
Blood (2021) 137 (14): 1932–1944.
https://doi.org/10.1182/blood.2020006871
Published: 2021
Includes: Multimedia, Supplemental data