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Journal Articles

Differential Response to ATR/Chk1 Inhibition in Preleukemia and Transformed Leukemia in an MLL-ENL Model of Leukemogenesis Reflects Enrichment for Myc-Transcriptional Program

Pavla Chaloupkova, Lubos Janotka, Jan Gursky, Nikola Niederlova, Monika Horvathova, Zuzana Jurtik Korbasova, Pavla Koralkova, Jiri Bartek, Vladimir Divoky

Blood (2024) 144 (Supplement 1): 5725.

https://doi.org/10.1182/blood-2024-207132

Published: 2024

Journal Articles

uRADAR: European Patients Referral Frame to Improve Access to New Drugs and Therapies in Ultra-Rare Anemia Disorders and Severe Hereditary Spherocytosis

Blood (2024) 144 (Supplement 1): 794.

https://doi.org/10.1182/blood-2024-201501

Published: 2024

Journal Articles

Metabolomic Profiling Confirms the Key Role of Oxidative Stress in the Pathophysiology of Diamond-Blackfan Anemia

Ondrej Jahoda, Dana Dobesova, Katarina Hlusickova Kapralova, Simona Kurekova, Dagmar Pospisilova, Vladimir Divoky, David Friedecky, Monika Horvathova

Blood (2023) 142 (Supplement 1): 2734.

https://doi.org/10.1182/blood-2023-174840

Published: 2023

Journal Articles

Aging-Related Changes in Erythropoietic Activity and Iron Metabolism in a Mouse Model of Congenital Erythrocytosis with Human Gain-of-Function Erythropoietin Receptor

Barbora Kralova, Ondrej Jahoda, Jihyun Song, Katarina Hlusickova Kapralova, Lucie Sochorcova, Josef T. Prchal, Vladimir Divoky, Monika Horvathova

Blood (2021) 138 (Supplement 1): 938.

https://doi.org/10.1182/blood-2021-146747

Published: 2021

Journal Articles

Normal Hemoglobin Concentrations in Obstructive Sleep Apnea and Associated Neocytolysis-Mediated Hemolysis and Inflammation Mediated Suppression of Expected Elevated Hemoglobin

Jihyun Song, PhD, Krishna M Sundar, MD, Monika Horvathova, MSc, PhD, Tsewang Tashi, MD, Carsten Lundby, PhD, Tomas Ganz, MD PhD, Josef T. Prchal, MD

Blood (2019) 134 (Supplement_1): 3507.

https://doi.org/10.1182/blood-2019-131269

Published: 2019

Journal Articles

Malignancies and MDS in Patients with Diamond-Blackfan Anemia (DBA) from the Czech National DBA Registry

Dagmar Pospisilova, Prof MD PhD, Jaroslav Cermak, Monika Belickova, PhD, Monika Horvathova, MSc, PhD, Jana Volejnikova, MD

Blood (2019) 134 (Supplement_1): 5017.

https://doi.org/10.1182/blood-2019-126187

Published: 2019

Journal Articles

Pathophysiology of Obstructive Sleep Apnea (OSA) - Blood Cells’ Reactive Oxygen Species and Inflammation Prevent Polycythemia

Jihyun Song, PhD, Krishna M Sundar, MD, Christensen Robert, MD, Monika Horvathova, MSc, PhD, Barbora Kralova, MSc, Vladimir Divoky, PhD, Tomas Ganz, MD PhD, Josef T. Prchal, MD

Blood (2018) 132 (Supplement 1): 1028.

https://doi.org/10.1182/blood-2018-99-116658

Published: 2018

Journal Articles

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model

Daniel Garcia-Santos, Amel Hamdi, Zuzana Saxova, Carine Fillebeen, Kostas Pantopoulos, Monika Horvathova, Prem Ponka

Blood (2018) 131 (2): 236–246.

https://doi.org/10.1182/blood-2017-07-798728

Published: 2018

Includes: Supplemental data

Journal Articles

Large Deletions and Novel Mutations in Genes Coding for Ribosomal Proteins ( RPL11 , RPL35A , RPS19 ) in the Czech National Registry of Diamond-Blackfan Anemia (DBA)

Jana Volejnikova, MD, Petr Vojta, MSc, Zuzana Maceckova, MSc, Pavla Koralkova, MSc, Helena Urbankova, MSc, PhD, Monika Horvathova, MSc, PhD, Barbora Ludikova, MD PhD, Martina Sukova, MD, Pavel Timr, MD, Marian Hajduch, MD PhD, Dagmar Pospisilova, Prof. MD PhD

Blood (2017) 130 (Supplement 1): 3485.

https://doi.org/10.1182/blood.V130.Suppl_1.3485.3485

Published: 2017

Journal Articles

Inflammatory Signature, Oxidative Stress, and DNA Damage Response in DBA Pathogenesis

Katarina Kapralova, MSc, Zuzana Saxova, PhD, Barbora Kralova, MSc, Lucie Lanikova, PhD, Dagmar Pospisilova, Prof. MD PhD, Vladimir Divoky, PhD, Monika Horvathova, MSc, PhD

Blood (2017) 130 (Supplement 1): 2452.

https://doi.org/10.1182/blood.V130.Suppl_1.2452.2452

Published: 2017

Journal Articles

Characterization of Iron Metabolism in Mouse Model of Congenital Polycythemia with Human Gain-of-Function Erythropoietin Receptor

Barbora Kralova, MSc, Jihyun Song, PhD, Vladimir Divoky, PhD, Josef T. Prchal, MD, Monika Horvathova, MSc, PhD

Blood (2017) 130 (Supplement 1): 170.

https://doi.org/10.1182/blood.V130.Suppl_1.170.170

Published: 2017

Journal Articles

Two Novel Mutations in Ribosomal Proteins in the Czech National Diamond-Blackfan Anemia Registry

Zuzana Maceckova, MSc, Pavla Koralkova, MSc, Jana Volejnikova, MD PhD, Petr Vojta, MSc, Alexandra Jungova, MD, Zuzana Saxova, MSc, Renata Mojzikova, MSc, PhD, Marie Jarosova, MSc PhD, Ivana Hadacova, MD, Marian Hajduch, MD PhD, Monika Horvathova, MSc, PhD, Dagmar Pospisilova, MD PhD

Blood (2016) 128 (22): 3903.

https://doi.org/10.1182/blood.V128.22.3903.3903

Published: 2016

Journal Articles

Heme Oxygenase 1 Inhibition Reverses Anemia in β-Thalassemia Mice

Daniel Garcia-Santos, PhD, Amel Hamdi, PhD, Zuzana Zidova, MSc, Monika Horvathova, PhD, Prem Ponka, MD PhD FCMA

Blood (2016) 128 (22): 2462.

https://doi.org/10.1182/blood.V128.22.2462.2462

Published: 2016

Journal Articles

Cooperation of germ line JAK2 mutations E846D and R1063H in hereditary erythrocytosis with megakaryocytic atypia

Katarina Kapralova, Monika Horvathova, Christian Pecquet, Jana Fialova Kucerova, Dagmar Pospisilova, Emilie Leroy, Barbora Kralova, Jelena D. Milosevic Feenstra, Fiorella Schischlik, Robert Kralovics, Stefan N. Constantinescu, Vladimir Divoky

Blood (2016) 128 (10): 1418–1423.

https://doi.org/10.1182/blood-2016-02-698951

Published: 2016

Includes: Supplemental data

Journal Articles

Pathophysiology and Treatment of Beta-Thalassemia: Investigations of Heme Oxygenase 1 and Its Inhibitors

Daniel Garcia dos Santos, PhD, Zuzana Zidova, MSc, Marc Mikhael, PhD, Amel Hamdi, PhD, Monika Horvathova, PhD, Prem Ponka, MD PhD FCMA

Blood (2015) 126 (23): 3373.

https://doi.org/10.1182/blood.V126.23.3373.3373

Published: 2015

Journal Articles

Polycythemia of Mice with Human Gain-of-Function EPOR (mtH EPOR ) Is Transiently Corrected in Perinatal Life in Association with Low Epo and Increased Erythrocyte Phosphatidylserine Exposure

Jihyun Song, MS, Barbora Kralova, Monika Horvathova, PhD, Donghoon Yoon, PhD, Josef T. Prchal, MD, Vladimir Divoky, PhD

Blood (2015) 126 (23): 3335.

https://doi.org/10.1182/blood.V126.23.3335.3335

Published: 2015

Journal Articles

Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency

Zuzana Zidova, MSc, Daniel Garcia-Santos, PhD, Katarina Kapralova, MSc, Pavla Koralkova, MSc, Renata Mojzikova, PhD, Dalibor Dolezal, DVM, Prem Ponka, MD PhD FCMA, Vladimir Divoky, PhD, Monika Horvathova, PhD

Blood (2014) 124 (21): 4027.

https://doi.org/10.1182/blood.V124.21.4027.4027

Published: 2014

Journal Articles

JAK2 E846D Germline Mutation Associated with Erythrocytosis Causes Increased and Prolonged Epo-Induced Activation of STAT5

Katarina Kapralova, MSc, Monika Horvathova, PhD, Jana Kucerova, PhD, Dagmar Pospisilova, MD PhD, Emilie Leroy, Stefan N. Constantinescu, MD PhD, Vladimir Divoky, PhD

Blood (2014) 124 (21): 4008.

https://doi.org/10.1182/blood.V124.21.4008.4008

Published: 2014

Journal Articles

Uncovering the Role of Heme Oxygenase 1 in the Pathophysiology of β-Thalassemia

Daniel Garcia-Santos, PhD, Marc Mikhael, PhD, Monika Horvathova, PhD, Prem Ponka, MD PhD

Blood (2014) 124 (21): 1364.

https://doi.org/10.1182/blood.V124.21.1364.1364

Published: 2014

Journal Articles

Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme

Daniel Garcia-Santos, Matthias Schranzhofer, Monika Horvathova, Mehrad Mojtahed Jaberi, Jose Artur Bogo Chies, Alex D. Sheftel, Prem Ponka

Blood (2014) 123 (14): 2269–2277.

https://doi.org/10.1182/blood-2013-04-496760

Published: 2014

Includes: Supplemental data

NARROW

Differential Response to ATR/Chk1 Inhibition in Preleukemia and Transformed Leukemia in an MLL-ENL Model of Leukemogenesis Reflects Enrichment for Myc-Transcriptional Program

uRADAR: European Patients Referral Frame to Improve Access to New Drugs and Therapies in Ultra-Rare Anemia Disorders and Severe Hereditary Spherocytosis

Metabolomic Profiling Confirms the Key Role of Oxidative Stress in the Pathophysiology of Diamond-Blackfan Anemia

Aging-Related Changes in Erythropoietic Activity and Iron Metabolism in a Mouse Model of Congenital Erythrocytosis with Human Gain-of-Function Erythropoietin Receptor

Normal Hemoglobin Concentrations in Obstructive Sleep Apnea and Associated Neocytolysis-Mediated Hemolysis and Inflammation Mediated Suppression of Expected Elevated Hemoglobin

Malignancies and MDS in Patients with Diamond-Blackfan Anemia (DBA) from the Czech National DBA Registry

Pathophysiology of Obstructive Sleep Apnea (OSA) - Blood Cells’ Reactive Oxygen Species and Inflammation Prevent Polycythemia

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model

Large Deletions and Novel Mutations in Genes Coding for Ribosomal Proteins ( RPL11 , RPL35A , RPS19 ) in the Czech National Registry of Diamond-Blackfan Anemia (DBA)

Inflammatory Signature, Oxidative Stress, and DNA Damage Response in DBA Pathogenesis

Characterization of Iron Metabolism in Mouse Model of Congenital Polycythemia with Human Gain-of-Function Erythropoietin Receptor

Two Novel Mutations in Ribosomal Proteins in the Czech National Diamond-Blackfan Anemia Registry

Heme Oxygenase 1 Inhibition Reverses Anemia in β-Thalassemia Mice

Cooperation of germ line JAK2 mutations E846D and R1063H in hereditary erythrocytosis with megakaryocytic atypia

Pathophysiology and Treatment of Beta-Thalassemia: Investigations of Heme Oxygenase 1 and Its Inhibitors

Polycythemia of Mice with Human Gain-of-Function EPOR (mtH EPOR ) Is Transiently Corrected in Perinatal Life in Association with Low Epo and Increased Erythrocyte Phosphatidylserine Exposure

Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency

JAK2 E846D Germline Mutation Associated with Erythrocytosis Causes Increased and Prolonged Epo-Induced Activation of STAT5

Uncovering the Role of Heme Oxygenase 1 in the Pathophysiology of β-Thalassemia

Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme

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