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Mitch Raponi
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Journal Articles

Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia

Clinical Trials & Observations
Judith E. Karp, Tatiana I. Vener, Mitch Raponi, Ellen K. Ritchie, B. Douglas Smith, Steven D. Gore, Lawrence E. Morris, Eric J. Feldman, Jacqueline M. Greer, Sami Malek, Hetty E. Carraway, Valerie Ironside, Steven Galkin, Mark J. Levis, Michael A. McDevitt, Gail R. Roboz, Christopher D. Gocke, Carlo Derecho, John Palma, Yixin Wang, Scott H. Kaufmann, John J. Wright, Elizabeth Garret-Mayer
Journal: Blood
Blood (2012) 119 (1): 55–63.
https://doi.org/10.1182/blood-2011-08-370825
Published: 2012
Includes: Supplemental data
Journal Articles

RASGRP1:APTX Gene Expression Ratio Enriches for Responders to the Combination of Tipifarnib and Etoposide in Elderly Newly Diagnosed AML.

Mitch Raponi, PhD, Tatiana Vener, PhD, Carlo Derecho, MSc, Jacqueline Greer, RN, BSN, Sami Malek, MD, John Palma, PhD, Judith E Karp, MD
Journal: Blood
Blood (2009) 114 (22): 4154.
https://doi.org/10.1182/blood.V114.22.4154.4154
Published: 2009
Journal Articles

Farnesyltransferase Inhibitor Tipifarnib (Zarnestra) in Refractory Mantle Cell Lymphoma (MCL): A Therapeutic Target Only for Specific Patients Categorized by the 2-Gene Classifier for Predictive Response to Tipifarnib.

Delphine Rolland, Vincent Ribrag, Corinne Haioun, Herve Ghesquieres, MD, Fabrice Jardin, Reda Bouabdallah, Patricia Franchi, Josette Briere, Eric De Kerviler, Catherine Chassagne-Clement, Mitch Raponi, PhD, Remi Houlgatte, Jean-Philippe Jais, Catherine Thieblemont
Journal: Blood
Blood (2008) 112 (11): 1561.
https://doi.org/10.1182/blood.V112.11.1561.1561
Published: 2008
Journal Articles

A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia

Clinical Trials & Observations
Mitch Raponi, Jeffrey E. Lancet, Hongtao Fan, Lesley Dossey, Grace Lee, Ivana Gojo, Eric J. Feldman, Jason Gotlib, Lawrence E. Morris, Peter L. Greenberg, John J. Wright, Jean-Luc Harousseau, Bob Löwenberg, Richard M. Stone, Peter De Porre, Yixin Wang, Judith E. Karp
Journal: Blood
Blood (2008) 111 (5): 2589–2596.
https://doi.org/10.1182/blood-2007-09-112730
Published: 2008
Includes: Supplemental data
Journal Articles

A Two-Gene Classifier for Predicting Response to the Farnesyltransferase Inhibitor Tipifarnib in Acute Myeloid Leukemia.

Mitch Raponi, PhD, Jeffrey E. Lancet, MD, Hongtao Fan, PhD, Lesley Dossey, PhD, Grace Lee, MSc, Ivana Gojo, MD, Eric J. Feldman, MD, Jason Gotlib, MD, Lawrence E. Morris, MD, Peter L. Greenberg, MD, John J. Wright, MD, Jean-Luc Harousseau, MD, Bob Lowenberg, MD, Richard M. Stone, MD, Peter De Porre, MD, Yixin Wang, PhD, Judith E. Karp, MD
Journal: Blood
Blood (2007) 110 (11): 1445.
https://doi.org/10.1182/blood.V110.11.1445.1445
Published: 2007
Journal Articles

Gene Expression Profiling Predictive of Tipifarnib (ZARNESTRA ® , R115777) Response in Patients with Newly Diagnosed Acute Myeloid Leukemia.

Mitch Raponi, MD, Yi Zhang, PhD, Tim Jatkoe, MD, Jack Yu, PhD, Grace Lee, MD, Jeffrey E. Lancet, MD, Judith E. Karp, MD, Alain Thibault, MD, Yixin Wang
Journal: Blood
Blood (2005) 106 (11): 2785.
https://doi.org/10.1182/blood.V106.11.2785.2785
Published: 2005
Journal Articles

Identification of Molecular Predictors of Response to ZARNESTRA™ (Tipifarnib, R115777) in Relapsed and Refractory Acute Myeloid Leukemia.

Mitch Raponi, Bob Lowenberg, Jeffrey E. Lancet, Jean-Luc Harousseau, Richard Stone, Wayne Rackoff, Alain Thibault, Yi Zhang, David Atkins, Yixin Wang
Journal: Blood
Blood (2004) 104 (11): 861.
https://doi.org/10.1182/blood.V104.11.861.861
Published: 2004
Journal Articles

Tipifarnib (ZARNESTRA TM in Previously Untreated Poor-Risk AML of the Elderly: Updated Results of a Multicenter Phase 2 Trial.

Jeffrey E. Lancet, MD, Jason Gotlib, MD, Ivana Gojo, MD, Eric J. Feldman, MD, Lawrence Morris, MD, Alain Thibault, MD, Jane L. Liesveld, MD, Jacqueline Greer, RN, Kathleen Dugan, RN, Mitch Raponi, PhD, John J. Wright, MD, PhD, Peter L. Greenberg, MD, Judith E. Karp, MD
Journal: Blood
Blood (2004) 104 (11): 874.
https://doi.org/10.1182/blood.V104.11.874.874
Published: 2004